TY - JOUR AU - Ohlendorf, Lars AU - Velandia, John E. Diaz AU - Kónya, Krisztina AU - Ehlers, Peter AU - Villinger, Alexander AU - Langer, Peter TI - Synthesis and properties of 5,7-disubstituted 5,7-dihydropyrido[2,3-b:6,5-b]diindoles JF - ADVANCED SYNTHESIS & CATALYSIS J2 - ADV SYNTH CATAL VL - 359 PY - 2017 IS - 10 SP - 1758 EP - 1769 PG - 12 SN - 1615-4150 DO - 10.1002/adsc.201601390 UR - https://m2.mtmt.hu/api/publication/34113149 ID - 34113149 AB - A new and efficient two-step procedure for the preparation of 5,7-disubstituted 5,7-dihydropyrido[2,3-b:6,5-b]diindoles, containing aryl-, benzyl- as well as alkyl-substituents has been developed. This methodology consists of a chemo-selective double Suzuki-Miyaura cross-coupling reaction followed by a fourfold Buchwald-Hartwig amination reaction. UV/VIS absorption and fluorescence measurements have been carried out for a selected series of compounds. The results are summarized and compared with those of the isomeric 5,7-disubstituted 5-7-dihydropyrido[3,2-b:5,6-b]diindoles. LA - English DB - MTMT ER - TY - JOUR AU - Pajtás, Dávid AU - Kónya, Krisztina AU - Kiss, Attila AU - Džubák, Petr AU - Pethő, Zoltán Dénes AU - Varga, Zoltán AU - Panyi, György AU - Patonay, Tamás TI - Optimization of the Synthesis of Flavone–Amino Acid and Flavone–Dipeptide Hybrids via Buchwald–Hartwig Reaction JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM VL - 82 PY - 2017 IS - 9 SP - 4578 EP - 4587 PG - 10 SN - 0022-3263 DO - 10.1021/acs.joc.7b00124 UR - https://m2.mtmt.hu/api/publication/3245969 ID - 3245969 AB - The article describes the development of Buchwald–Hartwig amination of different bromoflavones with amino acid and peptide derivatives as nitrogen source giving unique structures. The previously observed racemization, which occurred during the synthesis of flavone-amino acid hybrids, was successfully prevented in most cases. The biological assays of these novel structures showed cytotoxic effects on different cancer cell lines. LA - English DB - MTMT ER - TY - JOUR AU - Pajtás, Dávid AU - Patonay, Tamás AU - Kónya, Krisztina TI - Synthesis of 8-Bromoflavone and Its Buchwald–Hartwig Reaction with Amines JF - SYNTHESIS-STUTTGART J2 - SYNTHESIS-STUTTGART VL - 48 PY - 2016 IS - 1 SP - 97 EP - 102 PG - 6 SN - 0039-7881 DO - 10.1055/s-0035-1560325 UR - https://m2.mtmt.hu/api/publication/2988364 ID - 2988364 AB - Simple and convenient synthesis of 8-bromoflavone was achieved, starting from 2-bromophenol through 3′-bromo-2′-hydroxyacetophenone whose preparation was managed to be solved by optimized Fries rearrangement. The Buchwald–Hartwig reaction of 8-bromoflavone with different type of primary and secondary amines was carried out. LA - English DB - MTMT ER - TY - JOUR AU - Balog, József András AU - Riedl, Zsuzsanna AU - Hajós, György AU - Miskolczy, Zsombor AU - Biczók, László TI - Novel fluorescent isoquinoline derivatives obtained via Buchwald-Hartwig coupling of isoquinolin-3-amines. Dedicated to Prof. Ferenc Fülöp on the occasion of his 60th birthday TS - Dedicated to Prof. Ferenc Fülöp on the occasion of his 60th birthday JF - ARKIVOC J2 - ARKIVOC VL - 2012 PY - 2012 IS - 5 SP - 109 EP - 119 PG - 11 SN - 1551-7012 DO - 10.3998/ark.5550190.0013.511 UR - https://m2.mtmt.hu/api/publication/1876884 ID - 1876884 N1 - Megjegyzés-23085715 PN Part 5 LA - English DB - MTMT ER - TY - JOUR AU - Komáromi, A AU - Novák, Zoltán TI - Examination of the aromatic amination catalyzed by palladium on charcoal JF - ADVANCED SYNTHESIS & CATALYSIS J2 - ADV SYNTH CATAL VL - 352 PY - 2010 IS - 9 SP - 1523 EP - 1532 PG - 10 SN - 1615-4150 DO - 10.1002/adsc.201000048 UR - https://m2.mtmt.hu/api/publication/1970995 ID - 1970995 AB - The Buchwald-Hartwig amination of aryl halides with secondary amines and functionalized aromatic amines catalyzed by solid-supported palladium is reported. The choices of ligand, base and solvent are crucial for the successful coupling. The ami-nation of aromatic iodides, bromides and chlorides can be easily achieved with palladium on charcoal in the presence of a biphenylphosphane-type ligand at 80-110 °C. In addition, the palladium on charcoal catalyst is easily separable after the reaction, and reusable several times with only small activity loss. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. LA - English DB - MTMT ER -