TY - JOUR AU - Honti, Viktor AU - Cinege, Gyöngyi Ilona AU - Csordás, Gábor AU - Kurucz, Judit Éva AU - Zsámboki, János AU - Evans, CJ AU - Banerjee, U AU - Andó, István TI - Variation of NimC1 expression in Drosophila stocks and transgenic strains. JF - FLY J2 - FLY VL - 7 PY - 2013 IS - 4 SP - 263 EP - 266 PG - 4 SN - 1933-6934 DO - 10.4161/fly.25654 UR - https://m2.mtmt.hu/api/publication/2372552 ID - 2372552 AB - The NimC1 molecule has been described as a phagocytosis receptor, and is being used as a marker for professional phagocytes, the plasmatocytes, in Drosophila melanogaster. In studies including tumor-biology, developmental biology, and cell mediated immunity, monoclonal antibodies (P1a and P1b) to the NimC1 antigen are used. As we observed that these antibodies did not react with plasmatocytes of several strains and genetic combinations, a molecular analysis was performed on the structure of the nimC1 gene. We found 2 deletions and an insertion within the nimC1 gene, which may result in the production of a truncated NimC1 protein. The NimC1 positivity was regained by recombining the mutation with a wild-type allele or by using nimC1 mutant lines under heterozygous conditions. By means of these procedures or gaining access to the recombined stock, NimC1 can be used as a marker for phagocytic cells in the majority of the possible genetic backgrounds. LA - English DB - MTMT ER - TY - JOUR AU - Zsámboki, János AU - Csordás, Gábor AU - Honti, Viktor AU - Pintér, Lajos AU - Bajusz, Izabella AU - Galgóczi, László Norbert AU - Andó, István AU - Kurucz, Judit Éva TI - Drosophila Nimrod proteins bind bacteria JF - CENTRAL EUROPEAN JOURNAL OF BIOLOGY J2 - CENT EUR J BIOL VL - 8 PY - 2013 IS - 7 SP - 633 EP - 645 PG - 13 SN - 1895-104X DO - 10.2478/s11535-013-0183-4 UR - https://m2.mtmt.hu/api/publication/2326115 ID - 2326115 N1 - Institute of Genetics, Biological Research Centre of the Hungarian Academy of Sciences, H-6726 Szeged, Hungary Department of Microbiology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary Cited By :14 Export Date: 19 January 2022 Correspondence Address: Kurucz, É.; Institute of Genetics, , H-6726 Szeged, Hungary; email: kurucz.eva@brc.mta.hu AB - Engulfment of foreign particles by phagocytes is initiated by the engagement of phagocytic receptors. We have previously reported that NimC1 is involved in the phagocytosis of bacteria in Drosophila melanogaster. We have identified a family of genes, the Nimrod gene superfamily, encoding characteristic NIM domain containing structural homologues of NimC1. In this work we studied the bacterium-binding properties of the Nimrod proteins by using a novel immunofluorescencebased flow cytometric assay. This method proved to be highly reproducible and suitable for investigations of the bacteriumbinding capacities of putative phagocytosis receptors. We found that NimC1, NimA, NimB1 and NimB2 bind bacteria significantly but differently. In this respect they are similar to other NIM domain containing receptors Eater and Draper. LA - English DB - MTMT ER - TY - JOUR AU - Honti, Viktor AU - Csordás, Gábor AU - Márkus, Róbert AU - Kurucz, Judit Éva AU - Jankovics, Ferenc AU - Andó, István TI - Cell lineage tracing reveals the plasticity of the hemocyte lineages and of the hematopoietic compartments in drosophila melanogaster JF - MOLECULAR IMMUNOLOGY J2 - MOL IMMUNOL VL - 47 PY - 2010 IS - 11-12 SP - 1997 EP - 2004 PG - 8 SN - 0161-5890 DO - 10.1016/j.molimm.2010.04.017 UR - https://m2.mtmt.hu/api/publication/1921048 ID - 1921048 N1 - Cited By :83 Export Date: 19 January 2022 CODEN: IMCHA Correspondence Address: Andó, I.; Institute of Genetics, Temesvári krt. 62, 6726 Szeged, Csongrád, Hungary; email: ando@brc.hu LA - English DB - MTMT ER - TY - JOUR AU - Honti, Viktor AU - Kurucz, Judit Éva AU - Csordás, Gábor AU - Laurinyecz, Barbara AU - Márkus, Róbert AU - Andó, István TI - In vivo detection of lamellocytes in Drosophila melanogaster JF - IMMUNOLOGY LETTERS J2 - IMMUNOL LETT VL - 126 PY - 2009 IS - 1-2 SP - 83 EP - 84 PG - 2 SN - 0165-2478 DO - 10.1016/j.imlet.2009.08.004 UR - https://m2.mtmt.hu/api/publication/1920812 ID - 1920812 N1 - Cited By :27 Export Date: 30 June 2022 CODEN: IMLED LA - English DB - MTMT ER - TY - JOUR AU - Márkus, Róbert AU - Laurinyecz, Barbara AU - Kurucz, Judit Éva AU - Honti, Viktor AU - Bajusz, Izabella AU - Sipos, Botond AU - Somogyi, Kálmán AU - Kronhamn, J AU - Hultmark, D AU - Andó, István TI - Sessile hemocytes as a hematopoietic compartment in drosophila melanogaster JF - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA J2 - P NATL ACAD SCI USA VL - 106 PY - 2009 IS - 12 SP - 4805 EP - 4809 PG - 5 SN - 0027-8424 DO - 10.1073/pnas.0801766106 UR - https://m2.mtmt.hu/api/publication/1920757 ID - 1920757 N1 - Cited By :174 Export Date: 30 June 2022 CODEN: PNASA LA - English DB - MTMT ER - TY - JOUR AU - Vilmos, Péter AU - Jankovics, Ferenc AU - Szathmári, Margit AU - Lukacsovich, Tamás AU - Henn, László AU - Erdélyi, Miklós TI - Live imaging reveals that the Drosophila actin-binding ERM protein, moesin, co-localizes with the mitotic spindle JF - EUROPEAN JOURNAL OF CELL BIOLOGY J2 - EUR J CELL BIOL VL - 88 PY - 2009 IS - 10 SP - 609 EP - 619 PG - 11 SN - 0171-9335 DO - 10.1016/j.ejcb.2009.05.006 UR - https://m2.mtmt.hu/api/publication/1920806 ID - 1920806 N1 - Megjegyzés-22176398 DI: 10.1016/j.ejcb.2009.05.006 LA - English DB - MTMT ER - TY - JOUR AU - Kurucz, Judit Éva AU - Váczi, Balázs AU - Márkus, Róbert AU - Laurinyecz, Barbara AU - Vilmos, Péter AU - Zsámboki, János AU - Csorba, Kinga AU - Gateff, E AU - Hultmark, D AU - Andó, István TI - Definition of Drosophila hemocyte subsets by cell-type specific antigens JF - ACTA BIOLOGICA HUNGARICA (1983-2018) J2 - ACTA BIOL HUNG VL - 58 PY - 2007 IS - Suppl. 1 SP - 95 EP - 111 PG - 17 SN - 0236-5383 DO - 10.1556/ABiol.58.2007.Suppl.8 UR - https://m2.mtmt.hu/api/publication/1915261 ID - 1915261 AB - We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. Oil the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmalocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged ill four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocyles. LA - English DB - MTMT ER - TY - JOUR AU - Kurucz, Judit Éva AU - Márkus, Róbert AU - Zsámboki, János AU - Medzihradszky F., Katalin AU - Darula, Zsuzsanna AU - Vilmos, Péter AU - Udvardy, Andor AU - Krausz, Ildikó AU - Lukacsovich, Tamás AU - Gateff, E AU - Zettervall, CJ AU - Hultmark, D AU - Andó, István TI - Nimrod, a Putative Phagocytosis Receptor With Egf Repeats in Drosophila Plasmatocytes JF - CURRENT BIOLOGY J2 - CURR BIOL VL - 17 PY - 2007 IS - 7 SP - 649 EP - 654 PG - 6 SN - 0960-9822 DO - 10.1016/j.cub.2007.02.041 UR - https://m2.mtmt.hu/api/publication/1915010 ID - 1915010 N1 - Megjegyzés-22232309 Z9: 60 DI: 10.1016/j.cub.2007.02.041 LA - English DB - MTMT ER - TY - JOUR AU - Jankovics, Ferenc AU - Brunner, D TI - Transiently reorganized microtubules are essential for zippering during dorsal closure in Drosophila melanogaster JF - DEVELOPMENTAL CELL J2 - DEV CELL VL - 11 PY - 2006 SP - 375 EP - 385 PG - 11 SN - 1534-5807 UR - https://m2.mtmt.hu/api/publication/1914902 ID - 1914902 LA - English DB - MTMT ER - TY - JOUR AU - Zettervall, CJ AU - Anderl, I AU - Williams, MJ AU - Palmer, R AU - Kurucz, Judit Éva AU - Andó, István AU - Hultmark, D TI - A directed screen for genes involved in Drosophila blood cell activation JF - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA J2 - P NATL ACAD SCI USA VL - 101 PY - 2004 IS - 39 SP - 14192 EP - 14197 PG - 6 SN - 0027-8424 DO - 10.1073/pnas.0403789101 UR - https://m2.mtmt.hu/api/publication/1913536 ID - 1913536 LA - English DB - MTMT ER - TY - JOUR AU - Kurucz, Judit Éva AU - Zettervall, CJ AU - Sinka, Rita AU - Vilmos, Péter AU - Pivarcsi, A AU - Ekengren, S AU - Hegedűs, Zoltán AU - Andó, István AU - Hultmark, D TI - Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila JF - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA J2 - P NATL ACAD SCI USA VL - 100 PY - 2003 IS - 5 SP - 2622 EP - 2627 PG - 6 SN - 0027-8424 DO - 10.1073/pnas.0436940100 UR - https://m2.mtmt.hu/api/publication/1912851 ID - 1912851 LA - English DB - MTMT ER -