TY  - JOUR
AU  - Jócsák, Gergely
AU  - Kiss, Dávid Sándor
AU  - Tóth, István
AU  - Goszleth, Gréta
AU  - Bartha, Tibor
AU  - Frenyó V., László
AU  - Horváth, Tamás
AU  - Zsarnovszky, Attila
TI  - Comparison of individual and combined effects of four endocrine disruptors on estrogen receptor beta transcription in cerebellar cell culture: The modulatory role of estradiol and triiodo-thyronine
JF  - INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
J2  - INT J ENV RES PUB HE
VL  - 13
PY  - 2016
IS  - 6
PG  - 14
SN  - 1661-7827
DO  - 10.3390/ijerph13060619
UR  - https://m2.mtmt.hu/api/publication/3089063
ID  - 3089063
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Qu, ZD
AU  - Thacker, M
AU  - Castelucci, P
AU  - Bagyánszki, Mária
AU  - Epstein, ML
AU  - Furness, JB
TI  - Immunohistochemical analysis of neuron types in the mouse small intestine.
JF  - CELL AND TISSUE RESEARCH
J2  - CELL TISSUE RES
VL  - 334
PY  - 2008
IS  - 2
SP  - 147
EP  - 161
PG  - 15
SN  - 0302-766X
DO  - 10.1007/s00441-008-0684-7
UR  - https://m2.mtmt.hu/api/publication/1311676
ID  - 1311676
AB  - The definition of the nerve cell types of the myenteric plexus of the mouse small intestine has become important, as more researchers turn to the use of mice with genetic mutations to analyze roles of specific genes and their products in enteric nervous system function and to investigate animal models of disease. We have used a suite of antibodies to define neurons by their shapes, sizes, and neurochemistry in the myenteric plexus. Anti-Hu antibodies were used to reveal all nerve cells, and the major subpopulations were defined in relation to the Hu-positive neurons. Morphological Type II neurons, revealed by anti-neurofilament and anti-calcitonin gene-related peptide antibodies, represented 26% of neurons. The axons of the Type II neurons projected through the circular muscle and submucosa to the mucosa. The cell bodies were immunoreactive for choline acetyltransferase (ChAT), and their terminals were immunoreactive for vesicular acetylcholine transporter (VAChT). Nitric oxide synthase (NOS) occurred in 29% of nerve cells. Most were also immunoreactive for vasoactive intestinal peptide, but they were not tachykinin (TK)-immunoreactive, and only 10% were ChAT-immunoreactive. Numerous NOS terminals occurred in the circular muscle. We deduced that 90% of NOS neurons were inhibitory motor neurons to the muscle (26% of all neurons) and 10% (3% of all neurons) were interneurons. Calretinin immunoreactivity was found in a high proportion of neurons (52%). Many of these had TK immunoreactivity. Small calretinin neurons were identified as excitatory neurons to the longitudinal muscle (about 20% of neurons, with ChAT/calretinin/+/- TK chemical coding). Excitatory neurons to the circular muscle (about 10% of neurons) had the same coding. Calretinin immunoreactivity also occurred in a proportion of Type II neurons. Thus, over 90% of neurons in the myenteric plexus of the mouse small intestine can be currently identified by their neurochemistry and shape.
LA  - English
DB  - MTMT
ER  -