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an abundant, promising raw material for fuel ethanol\nproduction. Although it has a high cellulose content, without\npretreatment it resists enzymatic hydrolysis, like most lignocellulosic\nmaterials. Wet oxidation (water, oxygen, mild alkali or acid, elevated\ntemperature and pressure) was investigated to enhance the enzymatic\ndigestibility of corn stover. Six different combinations of reaction\ntemperature, time, and pH were applied. The best conditions (60 g/L of\ncorn stover, 195degreesC, 15 min, 12 bar O-2, 2 g/L of Na2CO) increased\nthe enzymatic conversion of corn stover four times, compared to\nuntreated material. Under these conditions 60% of hemicellulose and 30%\nof lignin were solubilized, whereas 90% of cellulose remained in the\nsolid fraction. After 24-h hydrolysis at 50degreesC using 25 filter\npaper units (FPU)/g of drymatter (DM) biomass, the achieved conversion\nof cellulose to glucose was about 85%. Decreasing the hydrolysis\ntemperature to 40degreesC increased hydrolysis time from 24 to 72 h.\nDecreasing the enzyme loading to 5 FPU/g of DM biomass slightly\ndecreased the enzymatic conversion from 83.4 to 71%. 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