TY  - JOUR
AU  - Haines, David
AU  - Lekli, István
AU  - Teissier, P
AU  - Bak, István
AU  - Tósaki, Árpád
TI  - Role of haeme oxygenase-1 in resolution of oxidative stress-related pathologies: focus on cardiovascular, lung, neurological and kidney disorders
JF  - ACTA PHYSIOLOGICA
J2  - ACTA PHYSIOL
VL  - 204
PY  - 2012
IS  - 4
SP  - 487
EP  - 501
PG  - 15
SN  - 1748-1708
DO  - 10.1111/j.1748-1716.2011.02387.x
UR  - https://m2.mtmt.hu/api/publication/1823045
ID  - 1823045
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Dóka, Ottó
AU  - Ficzek, Gitta
AU  - Bicanic, D
AU  - Spruijt, R
AU  - Luterotti, S
AU  - Tóth, Magdolna
AU  - Buijnsters, JG
AU  - Végvári, György
TI  - Direct photothermal techniques for rapid quantification of total anthocyanin content in sour cherry cultivars
JF  - TALANTA
J2  - TALANTA
VL  - 84
PY  - 2011
IS  - 2
SP  - 341
EP  - 346
PG  - 6
SN  - 0039-9140
DO  - 10.1016/j.talanta.2011.01.007
UR  - https://m2.mtmt.hu/api/publication/1421726
ID  - 1421726
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Bak, István
AU  - Lekli, István
AU  - Juhász, Béla
AU  - Varga, E
AU  - Varga, Balázs
AU  - Gesztelyi, Rudolf
AU  - Szendrei, L
AU  - Tósaki, Árpád
TI  - Isolation and Analysis of Bioactive Constituents of Sour Cherry (Prunus cerasus) Seed Kernel: An Emerging Functional Food
JF  - JOURNAL OF MEDICINAL FOOD
J2  - J MED FOOD
VL  - 13
PY  - 2010
IS  - 4
SP  - 905
EP  - 910
PG  - 6
SN  - 1096-620X
DO  - 10.1089/jmf.2009.0188
UR  - https://m2.mtmt.hu/api/publication/1348209
ID  - 1348209
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Bak, István
AU  - Lekli, István
AU  - Juhász, Béla
AU  - Nagy, N
AU  - Varga, E
AU  - Váradi, Judit
AU  - Gesztelyi, Rudolf
AU  - Szabo, G
AU  - Szendrei, L
AU  - Bácskay, Ildikó
AU  - Vecsernyés, Miklós
AU  - Antal, Miklós
AU  - Fésüs, László
AU  - Boucher, F
AU  - de Leiris, J
AU  - Tósaki, Árpád
TI  - Cardioprotective mechanisms of Prunus cerasus (sour cherry) seed extract against ischemia-reperfusion-induced damage in isolated rat hearts
JF  - AMERICAN JOURNAL OF PHYSIOLOGY: HEART AND CIRCULATORY PHYSIOLOGY
J2  - AM J PHYSIOL HEART C
VL  - 291
PY  - 2006
IS  - 3
SP  - H1329
EP  - H1336
SN  - 0363-6135
DO  - 10.1152/ajpheart.01243.2005
UR  - https://m2.mtmt.hu/api/publication/1195203
ID  - 1195203
AB  - Cardioprotective mechanisms of Prunus cerasus (sour cherry) seed extract against ischemia-reperfusion-induced damage in isolated rat hearts. Am J Physiol Heart Circ Physiol 291: H1329-H1336, 2006. First published April 14, 2006; doi: 10.1152/ajpheart.01243.2005. The effects of kernel extract obtained from sour cherry (Prunus cerasus) seed on the postischemic cardiac recovery were studied in isolated working rat hearts. Rats were treated with various daily doses of the extract for 14 days, and hearts were then isolated and subjected to 30 min of global ischemia followed by 120 min of reperfusion. The incidence of ventricular fibrillation (VF) and tachycardia (VT) fell from their control values of 92% and 100% to 50% (not significant) and 58% (not significant), 17% (P < 0.05), and 25% (P < 0.05) with the doses of 10 mg/kg and 30 mg/kg of the extract, respectively. Lower concentrations of the extract (1 and 5 mg/kg) failed to significantly reduce the incidence of VF and VT during reperfusion. Sour cherry seed kernel extract (10 and 30 mg/kg) significantly improved the postischemic recovery of cardiac function (coronary flow, aortic flow, and left ventricular developed pressure) during reperfusion. We have also demonstrated that the extract-induced protection in cardiac function significantly reflected in a reduction of infarct size. Immunohistochemistry indicates that a reduction in caspase-3 activity and apoptotic cells by the extract, beside other potential action mechanisms of proanthocyanidin, trans-resveratrol, and flavonoid components of the extract, could be responsible for the cardioprotection in ischemic-reperfused myocardium.
LA  - English
DB  - MTMT
ER  -