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Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity
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Background The importance of measuring aortic pulse wave
velocity (PWVao), aortic augmentation index (Aix) and central
systolic blood pressure (SBPao) has been shown under different
clinical conditions; however, information on these parameters is
hard to obtain. The aim of this study was to evaluate the
accuracy of a new, easily applicable oscillometric device
(Arteriograph), determining these parameters simultaneously,
against invasive measurements. Methods Aortic Aix, SBPao and
PWVao were measured invasively during cardiac catheterization in
16, 55 and 22 cases, respectively, and compared with the values
measured by the Arteriograph. Results We found strong
correlation between the invasively measured aortic Aix and the
oscillometrically measured brachial Aix on either beat-to-beat
or mean value per patient basis (r=0.9, P<0.001; r=0.94,
P<0.001), which allowed the noninvasive calculation of the
aortic Aix without using generalized transfer function.
Similarly strong correlation (r=0.95, P<0.001) was found between
the invasively measured and the noninvasively calculated central
SBPao; furthermore, the BHS assessment of the paired differences
fulfilled the 'B' grading. The PWVao values measured invasively
and by Arteriograph were 9.41 +/- 1.8 m/s and 9.46 +/- 1.8 m/s,
respectively (mean +/- SD); furthermore, the Pearson's
correlation was 0.91 (P<0.001). The limits of agreement were
11.4% for aortic Aix and 1.59 m/s for PWVao. Conclusion Aix,
SBPao and PWVao, measured oscillometrically, showed strong
correlation with the invasively obtained values. The observed
limits of agreement are encouragingly low for accepting the
method for clinical use. Our results suggest that the PWVao
values, measured by Arteriograph, are close to the true aortic
PWV, determined invasively. J Hypertens 28: 2068-2075 (C) 2010
Wolters Kluwer Health vertical bar Lippincott Williams &
Wilkins.
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10014594"> <a href="/gui2/?type=authors&mode=browse&sel=10014594" target="_blank">Horvath, IG</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10023258"> <a href="/gui2/?type=authors&mode=browse&sel=10023258" target="_blank">Nemeth, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10021105"> <a href="/gui2/?type=authors&mode=browse&sel=10021105" target="_blank">Lenkey, Z</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Alessandri, N </span> <span class="author-type"> </span> ; <span class="author-name" > Tufano, F </span> <span class="author-type"> </span> ; <span class="author-name" > Kis, P </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016869"> <a href="/gui2/?type=authors&mode=browse&sel=10016869" target="_blank">Gaszner, B</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10016439"> <a href="/gui2/?type=authors&mode=browse&sel=10016439" target="_blank">Cziraki, A ✉</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1463458" mtid="1463458" target="_blank">Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF HYPERTENSION</span> <span class="journal-volume">28</span> : <span class="journal-issue">10</span> <span class="page"> pp. 2068-2075. , 8 p. </span> <span class="year">(2010)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1097/HJH.0b013e32833c8a1a" target="_blank" href="https://doi.org/10.1097/HJH.0b013e32833c8a1a"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000281867400015" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000281867400015"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="77957284980" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-77957284980"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="20651604" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=20651604&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:1463458 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 324</span> | Független: 304 | Függő: 20 | Nem jelölt: 0 | WoS jelölt: 302 | Scopus jelölt: 306 | WoS/Scopus jelölt: 316 | DOI jelölt: 303 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10014594"><a href="/gui2/?type=authors&mode=browse&sel=10014594" target="_blank">Horvath IG (<span class="authorship-author-name">Horváth Iván</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Szívgyógyászati Klinika</span> ; <span class="author-name" mtid="10023258"><a href="/gui2/?type=authors&mode=browse&sel=10023258" target="_blank">Nemeth A (<span class="authorship-author-name">Németh Ádám</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Szívgyógyászati Klinika</span> ; <span class="author-name" mtid="10021105"><a href="/gui2/?type=authors&mode=browse&sel=10021105" target="_blank">Lenkey Z (<span class="authorship-author-name">Lenkey Zsófia</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Doktori Iskolák">DI</span>/Klinikai Orvostudományok Doktori Iskola</span> ; <span class="author-name" >Alessandri N </span> ; <span class="author-name" >Tufano F </span> ; <span class="author-name" >Kis P </span> ; <span class="author-name" mtid="10016869"><a href="/gui2/?type=authors&mode=browse&sel=10016869" target="_blank">Gaszner B (<span class="authorship-author-name">Gaszner Balázs</span> <span class="authorAux-mtmt"> Kardiológia, NMR</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Szívgyógyászati Klinika</span> ; <span class="author-name" mtid="10016439"><a href="/gui2/?type=authors&mode=browse&sel=10016439" target="_blank">Cziraki A ✉ (<span class="authorship-author-name">Cziráki Attila</span> <span class="authorAux-mtmt"> Az endotél diszfunkció artériás stiffness és bi...</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Szívgyógyászati Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1463458" target="_blank">Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity</a></div> <div> <span class="journal-title">JOURNAL OF HYPERTENSION</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0263-6352">0263-6352</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1473-5598">1473-5598</a>)</span>: <span class="journal-volume">28</span> <span class="journal-issue">10</span> <span class="page"> pp 2068-2075 </span> <span class="year">(2010)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1097/HJH.0b013e32833c8a1a" target="_blank" href="https://doi.org/10.1097/HJH.0b013e32833c8a1a"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000281867400015" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000281867400015"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="77957284980" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-77957284980"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="20651604" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=20651604&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 324</span> | Független: 304 | Függő: 20 | Nem jelölt: 0 | WoS jelölt: 302 | Scopus jelölt: 306 | WoS/Scopus jelölt: 316 | DOI jelölt: 303 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1463458&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 1463458</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 1463458</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Utolsó módosítás: 2023.08.01. 11:35 Milánkovics Róbert (PTE ÁOK admin 4) </div> </div></div>
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Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus
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The aim of the present work was to investigate the impact of gender on resting cerebral blood flow velocity and cerebrovascular reserve capacity among diabetic patients. Middle cerebral artery mean blood flow velocity (MCAV) was measured in 72 patients suffering from type 1 diabetes mellitus at rest and 5, 10, 15 and 20 min after intravenous administration of 1 g acetazolamide. Cerebrovascular reserve was calculated as the maximal percent increase in MCAV after acetazolamide. Resting MCAV and cerebrovascular reserve capacity were compared between males and females. Resting cerebral blood flow velocity was higher in diabetic females than in males (men, 55.0+/-17.0 cm/s; women, 64.4+/-12.6 cm/s, p=0.0094). Cerebrovascular reserve capacity was similar in diabetic women and men (men, 44.0%+/-18.6%; women, 52.6%+/-32.9%, p=0.17). Comparing MCAV and cerebrovascular reserve capacity among the diabetic subgroups with disease duration < or = 10 years and >10 years, we did not detect any differences between women and men. Duration of diabetes was an important factor in determining cerebrovascular reserve capacity in both sexes: long-term diabetic women and men showed lower CRC values than diabetics with < or = 10 years disease duration. Cerebrovascular reserve capacity is similar in diabetic women and men. Taking into consideration that cerebrovascular reserve is normally higher among women, our finding indicates a relatively more serious worsening of cerebral vasodilatory responses in women suffering from type 1 diabetes.
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10013888"> <a href="/gui2/?type=authors&mode=browse&sel=10013888" target="_blank">Fulesdi, B ✉</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Limburg, M </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10021860"> <a href="/gui2/?type=authors&mode=browse&sel=10021860" target="_blank">Olah, L</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10000800"> <a href="/gui2/?type=authors&mode=browse&sel=10000800" target="_blank">Bereczki, D</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10000492"> <a href="/gui2/?type=authors&mode=browse&sel=10000492" target="_blank">Csiba, L</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10047626"> <a href="/gui2/?type=authors&mode=browse&sel=10047626" target="_blank">Kollar, J</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1052901" mtid="1052901" target="_blank">Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus</a></div> <div class="pub-info"> <span class="journal-title">ACTA DIABETOLOGICA</span> <span class="journal-volume">38</span> : <span class="journal-issue">3</span> <span class="page"> pp. 107-112. , 6 p. </span> <span class="year">(2001)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1007/s005920170006" target="_blank" href="https://doi.org/10.1007/s005920170006"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000173480600001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000173480600001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="0035675420" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0035675420"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="11827430" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11827430&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:1052901 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 6</span> | Független: 6 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 6 | Scopus jelölt: 6 | WoS/Scopus jelölt: 6 | DOI jelölt: 6 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10013888"><a href="/gui2/?type=authors&mode=browse&sel=10013888" target="_blank">Fulesdi B ✉ (<span class="authorship-author-name">Fülesdi Béla</span> <span class="authorAux-mtmt"> Aneszteziológia és intenzív terápia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Aneszteziológiai és Intenzív Terápiás Tanszék</span> ; <span class="author-name" >Limburg M </span> ; <span class="author-name" mtid="10021860"><a href="/gui2/?type=authors&mode=browse&sel=10021860" target="_blank">Olah L (<span class="authorship-author-name">Oláh László</span> <span class="authorAux-mtmt"> Neurológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék</span> ; <span class="author-name" mtid="10000800"><a href="/gui2/?type=authors&mode=browse&sel=10000800" target="_blank">Bereczki D (<span class="authorship-author-name">Bereczki Dániel</span> <span class="authorAux-mtmt"> Stroke</span>) </a> </span> ; <span class="author-name" mtid="10000492"><a href="/gui2/?type=authors&mode=browse&sel=10000492" target="_blank">Csiba L (<span class="authorship-author-name">Csiba László</span> <span class="authorAux-mtmt"> Neurológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék</span> ; <span class="author-name" mtid="10047626"><a href="/gui2/?type=authors&mode=browse&sel=10047626" target="_blank">Kollar J (<span class="authorship-author-name">Kollár József</span> <span class="authorAux-mtmt"> radiológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/<span title="Orvosi Képalkotó Intézet">OKI</span>/Radiológiai nem önálló Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1052901" target="_blank">Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus</a></div> <div> <span class="journal-title">ACTA DIABETOLOGICA</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0940-5429">0940-5429</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1432-5233">1432-5233</a>)</span>: <span class="journal-volume">38</span> <span class="journal-issue">3</span> <span class="page"> pp 107-112 </span> <span class="year">(2001)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1007/s005920170006" target="_blank" href="https://doi.org/10.1007/s005920170006"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000173480600001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000173480600001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="0035675420" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0035675420"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="11827430" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11827430&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 6</span> | Független: 6 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 6 | Scopus jelölt: 6 | WoS/Scopus jelölt: 6 | DOI jelölt: 6 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1052901&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 7 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 1052901</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 1052901</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Utolsó módosítás: 2022.04.11. 12:04 Tichy Rita (SE_KK_Admin5_TR, admin) </div> </div></div>
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The aim of the study was to test the hypothesis that cerebrovascular reserve capacity and cerebrovascular reactivity are impaired in patients suffering from non insulin-dependent diabetes mellitus. We also intended to investigate factors which may influence resting cerebral blood flow velocity and cerebrovascular reserve capacity. A total of 28 patients suffering from type II diabetes mellitus and 20 healthy control subjects were studied. Based on diabetes duration patients were divided into two groups: subjects with > 10 years and those with < or = 10 years disease duration. Middle cerebral artery mean blood flow velocities were measured at rest and after intravenous administration of 1g acetazolamide. Cerebrovascular reactivity and reserve capacity were calculated. Blood glucose, insulin, glycosylated hemoglobin, hemostatic factors (fibrinogen, alpha-2 macroglobulin and von Willebrand factor antigen) were determined. Cerebrovascular reactivity and reserve capacity values were compared between the two diabetic subgroups and controls. Correlations between laboratory parameters and cerebrovascular reserve were investigated by linear regression analysis. Resting cerebral blood flow velocity was similar in controls and in the two diabetic subgroups. Cerebrovascular reactivity was elevated for a shorter time in patients with > 10 years disease duration than in controls and short-term diabetic patients. Cerebrovascular reserve capacity was lower in the long-term diabetes group (means +/- SD: 39.6 +/- 20.7%) than in patients with < or = 10 years disease duration (63.3 +/- 17.4%, p < 0.02 after Bonferroni correction). Cerebrovascular reserve capacity was inversely related to the duration of the disease (R = 0.53, p < 0.003). None of the determined laboratory factors had any relation with resting cerebral blood flow and cerebrovascular reserve capacity. The vasodilatory ability of cerebral arterioles is diminished in long-standing type II diabetes mellitus.
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10013888"> <a href="/gui2/?type=authors&mode=browse&sel=10013888" target="_blank">Fulesdi, B ✉</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Limburg, M </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10000800"> <a href="/gui2/?type=authors&mode=browse&sel=10000800" target="_blank">Bereczki, D</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10044795"> <a href="/gui2/?type=authors&mode=browse&sel=10044795" target="_blank">Kaplar, M</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10037125"> <a href="/gui2/?type=authors&mode=browse&sel=10037125" target="_blank">Molnar, C</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10001945"> <a href="/gui2/?type=authors&mode=browse&sel=10001945" target="_blank">Kappelmayer, J</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Neuwirth, G </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10000492"> <a href="/gui2/?type=authors&mode=browse&sel=10000492" target="_blank">Csiba, L</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1052918" mtid="1052918" target="_blank">Cerebrovascular reactivity and reserve capacity in type II diabetes mellitus</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF DIABETES AND ITS COMPLICATIONS</span> <span class="journal-volume">13</span> : <span class="journal-issue">4</span> <span class="page"> pp. 191-199. , 9 p. </span> <span class="year">(1999)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1016/S1056-8727(99)00044-6" target="_blank" href="https://doi.org/10.1016/S1056-8727%2899%2900044-6"> DOI </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:blue" title="115747" target="_blank" href="http://hdl.handle.net/2437/115747"> DEA </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000084263600004" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000084263600004"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="0344806271" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0344806271"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10616858" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10616858&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:1052918 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 70</span> | Független: 64 | Függő: 6 | Nem jelölt: 0 | WoS jelölt: 63 | Scopus jelölt: 69 | WoS/Scopus jelölt: 70 | DOI jelölt: 63 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10013888"><a href="/gui2/?type=authors&mode=browse&sel=10013888" target="_blank">Fulesdi B ✉ (<span class="authorship-author-name">Fülesdi Béla</span> <span class="authorAux-mtmt"> Aneszteziológia és intenzív terápia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Aneszteziológiai és Intenzív Terápiás Tanszék</span> ; <span class="author-name" >Limburg M </span> ; <span class="author-name" mtid="10000800"><a href="/gui2/?type=authors&mode=browse&sel=10000800" target="_blank">Bereczki D (<span class="authorship-author-name">Bereczki Dániel</span> <span class="authorAux-mtmt"> Stroke</span>) </a> </span> ; <span class="author-name" mtid="10044795"><a href="/gui2/?type=authors&mode=browse&sel=10044795" target="_blank">Kaplar M (<span class="authorship-author-name">Káplár Miklós</span> <span class="authorAux-mtmt"> Diabetológia</span>) </a> </span> ; <span class="author-name" mtid="10037125"><a href="/gui2/?type=authors&mode=browse&sel=10037125" target="_blank">Molnar C (<span class="authorship-author-name">Molnár Csilla</span> <span class="authorAux-mtmt"> aneszteziológia-intenzív terápia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Aneszteziológiai és Intenzív Terápiás Tanszék</span> ; <span class="author-name" mtid="10001945"><a href="/gui2/?type=authors&mode=browse&sel=10001945" target="_blank">Kappelmayer J (<span class="authorship-author-name">Kappelmayer János</span> <span class="authorAux-mtmt"> Haemostasis, leukemiák</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Laboratóriumi Medicina Intézet</span> ; <span class="author-name" >Neuwirth G </span> ; <span class="author-name" mtid="10000492"><a href="/gui2/?type=authors&mode=browse&sel=10000492" target="_blank">Csiba L (<span class="authorship-author-name">Csiba László</span> <span class="authorAux-mtmt"> Neurológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1052918" target="_blank">Cerebrovascular reactivity and reserve capacity in type II diabetes mellitus</a></div> <div> <span class="journal-title">JOURNAL OF DIABETES AND ITS COMPLICATIONS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1056-8727">1056-8727</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1873-460X">1873-460X</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">4</span> <span class="page"> pp 191-199 </span> <span class="year">(1999)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1016/S1056-8727(99)00044-6" target="_blank" href="https://doi.org/10.1016/S1056-8727%2899%2900044-6"> DOI </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:blue" title="115747" target="_blank" href="http://hdl.handle.net/2437/115747"> DEA </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000084263600004" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000084263600004"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="0344806271" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0344806271"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10616858" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10616858&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 70</span> | Független: 64 | Függő: 6 | Nem jelölt: 0 | WoS jelölt: 63 | Scopus jelölt: 69 | WoS/Scopus jelölt: 70 | DOI jelölt: 63 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1052918&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 1052918</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 1052918</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Utolsó módosítás: 2023.07.23. 21:22 MTMT API (MTMT API user, admin) </div> </div></div>
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Cerebrovascular reactivity in hypertensive patients: A transcranial Doppler study
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PURPOSE: We studied the usefulness of transcranial Doppler sonography for assessing changes in vasoreactivity in patients with hypertension and the hemodynamic consequences of hypertension. METHODS: The study group comprised 25 patients with chronic severe hypertension and 25 age- and sex-matched healthy subjects. Cerebrovascular reserve capacity was assessed by transcranial Doppler recording of the blood flow velocity in both middle cerebral arteries before and 5, 10, 15, and 20 minutes after intravenous injection of 1 g of acetazolamide (Diamox). Blood pressure, blood gases, and other blood parameters were also measured before and after acetazolamide injection. The sizes of the left atrium, left ventricle, and aortic root were measured by echocardiography and correlated with the vasoreactivity after acetazolamide injection. RESULTS: After acetazolamide injection, no significant changes in blood pressure were observed in either group. The mean blood flow velocity in the middle cerebral arteries of hypertensive patients (60.8 +/- 2.6 cm/sec) was not significantly different from that of controls (58.8 +/- 1.9 cm/sec) before acetazolamide injection. Ten minutes after acetazolamide injection, the percentage change in blood flow velocity was significantly lower in the hypertensive group (36.2 +/- 4.5%) than in the controls (52.6 +/- 3.7%). A significant negative correlation (p < 0.05) between decreased vasoreactivity and increased size of the left atrium and aortic root was observed. CONCLUSIONS: Vasoreactivity decreases in hypertensive patients without neurologic deficits or computed tomography abnormalities. Enlargement of the left atrium correlates well with the severity of the impairment in vasoreactivity. Transcranial Doppler sonography can be a sensitive tool in the investigation of vascular impairment caused by hypertension and in the follow-up of hypertensive patients.
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10049398"> <a href="/gui2/?type=authors&mode=browse&sel=10049398" target="_blank">Ficzere, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10044515"> <a href="/gui2/?type=authors&mode=browse&sel=10044515" target="_blank">Valikovics, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10013888"> <a href="/gui2/?type=authors&mode=browse&sel=10013888" target="_blank">Fulesdi, B</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Juhasz, A </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10038694"> <a href="/gui2/?type=authors&mode=browse&sel=10038694" target="_blank">Czuriga, I</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10000492"> <a href="/gui2/?type=authors&mode=browse&sel=10000492" target="_blank">Csiba, L</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1052926" mtid="1052926" target="_blank">Cerebrovascular reactivity in hypertensive patients: A transcranial Doppler study</a></div> <div class="pub-info"> <span class="journal-title">JOURNAL OF CLINICAL ULTRASOUND</span> <span class="journal-volume">25</span> : <span class="journal-issue">7</span> <span class="page"> pp. 383-389. , 7 p. </span> <span class="year">(1997)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="10.1002/(SICI)1097-0096(199709)25:7<383::AID-JCU6>3.0.CO;2-6" target="_blank" href="https://doi.org/10.1002/%28SICI%291097-0096%28199709%2925%3A7%3C383%3A%3AAID-JCU6%3E3.0.CO%3B2-6"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="A1997XR78000006" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/A1997XR78000006"> WoS </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:blue" title="161394" target="_blank" href="http://hdl.handle.net/2437/161394"> DEA </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="0030746718" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0030746718"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="9282804" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9282804&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="deleted-record">Zárolt</span> <span class="short-pub-mtid"> Közlemény:1052926 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core">Forrás Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 67</span> | Független: 50 | Függő: 17 | Nem jelölt: 0 | WoS jelölt: 60 | Scopus jelölt: 55 | WoS/Scopus jelölt: 66 | DOI jelölt: 55 (Nem nyilvános: 1) </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10049398"><a href="/gui2/?type=authors&mode=browse&sel=10049398" target="_blank">Ficzere A (<span class="authorship-author-name">Ficzere Andrea</span> <span class="authorAux-mtmt"> Neurológia, Reumatológia, Neuroszonológia</span>) </a> </span> <span class="author-affil">Uzsoki Utcai Kórház</span> ; <span class="author-name" mtid="10044515"><a href="/gui2/?type=authors&mode=browse&sel=10044515" target="_blank">Valikovics A (<span class="authorship-author-name">Valikovics Attila</span> <span class="authorAux-mtmt"> Neurológia, pszichiátria</span>) </a> </span> ; <span class="author-name" mtid="10013888"><a href="/gui2/?type=authors&mode=browse&sel=10013888" target="_blank">Fulesdi B (<span class="authorship-author-name">Fülesdi Béla</span> <span class="authorAux-mtmt"> Aneszteziológia és intenzív terápia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Aneszteziológiai és Intenzív Terápiás Tanszék</span> ; <span class="author-name" >Juhasz A </span> ; <span class="author-name" mtid="10038694"><a href="/gui2/?type=authors&mode=browse&sel=10038694" target="_blank">Czuriga I (<span class="authorship-author-name">Czuriga István</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> ; <span class="author-name" mtid="10000492"><a href="/gui2/?type=authors&mode=browse&sel=10000492" target="_blank">Csiba L (<span class="authorship-author-name">Csiba László</span> <span class="authorAux-mtmt"> Neurológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1052926" target="_blank">Cerebrovascular reactivity in hypertensive patients: A transcranial Doppler study</a></div> <div> <span class="journal-title">JOURNAL OF CLINICAL ULTRASOUND</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0091-2751">0091-2751</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1097-0096">1097-0096</a>)</span>: <span class="journal-volume">25</span> <span class="journal-issue">7</span> <span class="page"> pp 383-389 </span> <span class="year">(1997)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="10.1002/(SICI)1097-0096(199709)25:7<383::AID-JCU6>3.0.CO;2-6" target="_blank" href="https://doi.org/10.1002/%28SICI%291097-0096%28199709%2925%3A7%3C383%3A%3AAID-JCU6%3E3.0.CO%3B2-6"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="A1997XR78000006" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/A1997XR78000006"> WoS </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:blue" title="161394" target="_blank" href="http://hdl.handle.net/2437/161394"> DEA </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="0030746718" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0030746718"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="9282804" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9282804&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 67</span> | Független: 50 | Függő: 17 | Nem jelölt: 0 | WoS jelölt: 60 | Scopus jelölt: 55 | WoS/Scopus jelölt: 66 | DOI jelölt: 55 (Nem nyilvános: 1) </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1052926&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 1052926</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 1052926</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS</span> </div> <div class="lastModified">Utolsó módosítás: 2020.01.24. 11:03 DE API (DE_API_5, admin) </div> <div class="lockedBy">Ideiglenesen zárolva 2022.02.12. 10:03 MTMT API (MTMT API user, admin) </div> </div></div>