@article{MTMT:1463458,
	title = {Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity},
	url = {https://m2.mtmt.hu/api/publication/1463458},
	author = {Horváth, Iván and Németh, Ádám and Lenkey, Zsófia and Alessandri, N and Tufano, F and Kis, P and Gaszner, Balázs and Cziráki, Attila},
	doi = {10.1097/HJH.0b013e32833c8a1a},
	journal-iso = {J HYPERTENSION},
	journal = {JOURNAL OF HYPERTENSION},
	volume = {28},
	unique-id = {1463458},
	issn = {0263-6352},
	abstract = {Background The importance of measuring aortic pulse wave 
		velocity (PWVao), aortic augmentation index (Aix) and central 
		systolic blood pressure (SBPao) has been shown under different 
		clinical conditions; however, information on these parameters is 
		hard to obtain. The aim of this study was to evaluate the 
		accuracy of a new, easily applicable oscillometric device 
		(Arteriograph), determining these parameters simultaneously, 
		against invasive measurements. Methods Aortic Aix, SBPao and 
		PWVao were measured invasively during cardiac catheterization in 
		16, 55 and 22 cases, respectively, and compared with the values 
		measured by the Arteriograph. Results We found strong 
		correlation between the invasively measured aortic Aix and the 
		oscillometrically measured brachial Aix on either beat-to-beat 
		or mean value per patient basis (r=0.9, P<0.001; r=0.94, 
		P<0.001), which allowed the noninvasive calculation of the 
		aortic Aix without using generalized transfer function. 
		Similarly strong correlation (r=0.95, P<0.001) was found between 
		the invasively measured and the noninvasively calculated central 
		SBPao; furthermore, the BHS assessment of the paired differences 
		fulfilled the 'B' grading. The PWVao values measured invasively 
		and by Arteriograph were 9.41 +/- 1.8 m/s and 9.46 +/- 1.8 m/s, 
		respectively (mean +/- SD); furthermore, the Pearson's 
		correlation was 0.91 (P<0.001). The limits of agreement were 
		11.4% for aortic Aix and 1.59 m/s for PWVao. Conclusion Aix, 
		SBPao and PWVao, measured oscillometrically, showed strong 
		correlation with the invasively obtained values. The observed 
		limits of agreement are encouragingly low for accepting the 
		method for clinical use. Our results suggest that the PWVao 
		values, measured by Arteriograph, are close to the true aortic 
		PWV, determined invasively. J Hypertens 28: 2068-2075 (C) 2010 
		Wolters Kluwer Health vertical bar Lippincott Williams & 
		Wilkins.},
	keywords = {VALIDATION; CORONARY-ARTERY-DISEASE; MORTALITY; HYPERTENSION; EVENTS; Travel; Reflection; COMPLIOR; SPHYGMOCOR; STIFFNESS; STAGE RENAL-DISEASE; pulse wave velocity; oscillometric method; invasive measurement; augmentation index; Arteriograph; arterial stiffness},
	year = {2010},
	eissn = {1473-5598},
	pages = {2068-2075}
}

@article{MTMT:1052901,
	title = {Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus},
	url = {https://m2.mtmt.hu/api/publication/1052901},
	author = {Fülesdi, Béla and Limburg, M and Oláh, László and Bereczki, Dániel and Csiba, László and Kollár, József},
	doi = {10.1007/s005920170006},
	journal-iso = {ACTA DIABETOL},
	journal = {ACTA DIABETOLOGICA},
	volume = {38},
	unique-id = {1052901},
	issn = {0940-5429},
	abstract = {The aim of the present work was to investigate the impact of gender on resting cerebral blood flow velocity and cerebrovascular reserve capacity among diabetic patients. Middle cerebral artery mean blood flow velocity (MCAV) was measured in 72 patients suffering from type 1 diabetes mellitus at rest and 5, 10, 15 and 20 min after intravenous administration of 1 g acetazolamide. Cerebrovascular reserve was calculated as the maximal percent increase in MCAV after acetazolamide. Resting MCAV and cerebrovascular reserve capacity were compared between males and females. Resting cerebral blood flow velocity was higher in diabetic females than in males (men, 55.0+/-17.0 cm/s; women, 64.4+/-12.6 cm/s, p=0.0094). Cerebrovascular reserve capacity was similar in diabetic women and men (men, 44.0%+/-18.6%; women, 52.6%+/-32.9%, p=0.17). Comparing MCAV and cerebrovascular reserve capacity among the diabetic subgroups with disease duration < or = 10 years and >10 years, we did not detect any differences between women and men. Duration of diabetes was an important factor in determining cerebrovascular reserve capacity in both sexes: long-term diabetic women and men showed lower CRC values than diabetics with < or = 10 years disease duration. Cerebrovascular reserve capacity is similar in diabetic women and men. Taking into consideration that cerebrovascular reserve is normally higher among women, our finding indicates a relatively more serious worsening of cerebral vasodilatory responses in women suffering from type 1 diabetes.},
	year = {2001},
	eissn = {1432-5233},
	pages = {107-112},
	orcid-numbers = {Bereczki, Dániel/0000-0002-8374-0500}
}

@article{MTMT:1052918,
	title = {Cerebrovascular reactivity and reserve capacity in type II diabetes mellitus},
	url = {https://m2.mtmt.hu/api/publication/1052918},
	author = {Fülesdi, Béla and Limburg, M and Bereczki, Dániel and Káplár, Miklós and Molnár, Csilla and Kappelmayer, János and Neuwirth, G and Csiba, László},
	doi = {10.1016/S1056-8727(99)00044-6},
	journal-iso = {J DIABETES COMPLICAT},
	journal = {JOURNAL OF DIABETES AND ITS COMPLICATIONS},
	volume = {13},
	unique-id = {1052918},
	issn = {1056-8727},
	abstract = {The aim of the study was to test the hypothesis that cerebrovascular reserve capacity and cerebrovascular reactivity are impaired in patients suffering from non insulin-dependent diabetes mellitus. We also intended to investigate factors which may influence resting cerebral blood flow velocity and cerebrovascular reserve capacity. A total of 28 patients suffering from type II diabetes mellitus and 20 healthy control subjects were studied. Based on diabetes duration patients were divided into two groups: subjects with > 10 years and those with < or = 10 years disease duration. Middle cerebral artery mean blood flow velocities were measured at rest and after intravenous administration of 1g acetazolamide. Cerebrovascular reactivity and reserve capacity were calculated. Blood glucose, insulin, glycosylated hemoglobin, hemostatic factors (fibrinogen, alpha-2 macroglobulin and von Willebrand factor antigen) were determined. Cerebrovascular reactivity and reserve capacity values were compared between the two diabetic subgroups and controls. Correlations between laboratory parameters and cerebrovascular reserve were investigated by linear regression analysis. Resting cerebral blood flow velocity was similar in controls and in the two diabetic subgroups. Cerebrovascular reactivity was elevated for a shorter time in patients with > 10 years disease duration than in controls and short-term diabetic patients. Cerebrovascular reserve capacity was lower in the long-term diabetes group (means +/- SD: 39.6 +/- 20.7%) than in patients with < or = 10 years disease duration (63.3 +/- 17.4%, p < 0.02 after Bonferroni correction). Cerebrovascular reserve capacity was inversely related to the duration of the disease (R = 0.53, p < 0.003). None of the determined laboratory factors had any relation with resting cerebral blood flow and cerebrovascular reserve capacity. The vasodilatory ability of cerebral arterioles is diminished in long-standing type II diabetes mellitus.},
	year = {1999},
	eissn = {1873-460X},
	pages = {191-199},
	orcid-numbers = {Bereczki, Dániel/0000-0002-8374-0500}
}

@article{MTMT:1052926,
	title = {Cerebrovascular reactivity in hypertensive patients: A transcranial Doppler study},
	url = {https://m2.mtmt.hu/api/publication/1052926},
	author = {Ficzere, Andrea and Valikovics, Attila and Fülesdi, Béla and Juhasz, A and Czuriga, István and Csiba, László},
	doi = {10.1002/(SICI)1097-0096(199709)25:7<383::AID-JCU6>3.0.CO;2-6},
	journal-iso = {J CLIN ULTRASOUND},
	journal = {JOURNAL OF CLINICAL ULTRASOUND},
	volume = {25},
	unique-id = {1052926},
	issn = {0091-2751},
	abstract = {PURPOSE: We studied the usefulness of transcranial Doppler sonography for assessing changes in vasoreactivity in patients with hypertension and the hemodynamic consequences of hypertension. METHODS: The study group comprised 25 patients with chronic severe hypertension and 25 age- and sex-matched healthy subjects. Cerebrovascular reserve capacity was assessed by transcranial Doppler recording of the blood flow velocity in both middle cerebral arteries before and 5, 10, 15, and 20 minutes after intravenous injection of 1 g of acetazolamide (Diamox). Blood pressure, blood gases, and other blood parameters were also measured before and after acetazolamide injection. The sizes of the left atrium, left ventricle, and aortic root were measured by echocardiography and correlated with the vasoreactivity after acetazolamide injection. RESULTS: After acetazolamide injection, no significant changes in blood pressure were observed in either group. The mean blood flow velocity in the middle cerebral arteries of hypertensive patients (60.8 +/- 2.6 cm/sec) was not significantly different from that of controls (58.8 +/- 1.9 cm/sec) before acetazolamide injection. Ten minutes after acetazolamide injection, the percentage change in blood flow velocity was significantly lower in the hypertensive group (36.2 +/- 4.5%) than in the controls (52.6 +/- 3.7%). A significant negative correlation (p < 0.05) between decreased vasoreactivity and increased size of the left atrium and aortic root was observed. CONCLUSIONS: Vasoreactivity decreases in hypertensive patients without neurologic deficits or computed tomography abnormalities. Enlargement of the left atrium correlates well with the severity of the impairment in vasoreactivity. Transcranial Doppler sonography can be a sensitive tool in the investigation of vascular impairment caused by hypertension and in the follow-up of hypertensive patients.},
	year = {1997},
	eissn = {1097-0096},
	pages = {383-389}
}