TY  - JOUR
AU  - Dobor, József
AU  - Oltiné Varga, Margit
AU  - Yao, J
AU  - Chen, HL
AU  - Palko, G
AU  - Záray, Gyula
TI  - A new sample preparation method for determination of acidic drugs in sewage sludge applying microwave assisted solvent extraction followed by gas chromatography-mass spectrometry
JF  - MICROCHEMICAL JOURNAL
J2  - MICROCHEM J
VL  - 94
PY  - 2010
IS  - 1
SP  - 36
EP  - 41
PG  - 6
SN  - 0026-265X
DO  - 10.1016/j.microc.2009.08.007
UR  - https://m2.mtmt.hu/api/publication/1592975
ID  - 1592975
AB  - This paper presents a new sample preparation procedure for determination of selected acidic pharmaceuticals (ibuprofen, naproxen, ketoprofen, and diclofenac) in sewage sludge using microwave assisted solvent extraction, dispersive matrix extraction (DME) followed by the conventionally applied solid phase extraction (SPE), derivatization. and gas chromatography-mass spectrometry. The recoveries calculated from analytical data of spiked sludge samples changed in the range of 80-105%+/- 15% for the four pharmaceuticals in mixed and activated sludge depending on the efficiency of the clean-up procedure. The measured concentration values of ibuprofen and naproxen were identical in the mixed and the activated sludge samples. However, ketoprofen and diclofenac showed about twice as high concentration in activated sludge than in the mixed one independently of the applied extraction method. The typical concentration ranges of ibuprofen, naproxen, ketoprofen and diclofenac in sewage sludge were 10-30 ng/g, 30-50 ng/g, 50-130 ng/g, and 50-140 ng/g respectively. (C) 2009 Elsevier B.V. All rights reserved.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Oltiné Varga, Margit
AU  - Dobor, József
AU  - Helenkar, A
AU  - Jurecska, Laura
AU  - Yao, J
AU  - Záray, Gyula
TI  - Investigation of acidic pharmaceuticals in river water and sediment by microwave-assisted extraction and gas chromatography-mass spectrometry
JF  - MICROCHEMICAL JOURNAL
J2  - MICROCHEM J
VL  - 95
PY  - 2010
IS  - 2
SP  - 353
EP  - 358
PG  - 6
SN  - 0026-265X
DO  - 10.1016/j.microc.2010.02.010
UR  - https://m2.mtmt.hu/api/publication/1592969
ID  - 1592969
N1  - Department of Analytical Chemistry, Institute of Chemistry, L. Eötvös University, Pazmany Peter stny. 1/A, H-1117 Budapest, Hungary            
            Cooperative Research Centre of Environmental Sciences, L. Eötvös University, Pazmany Peter stny. 1/A, H-1518 Budapest, Hungary            
            China University of Geosciences, Wuhan, 430074 Hubei Province, China            
            Cited By :44            
            Export Date: 16 September 2019            
            CODEN: MICJA            
            Correspondence Address: Záray, G.; Department of Analytical Chemistry, Institute of Chemistry, L. Eötvös University, Pazmany Peter stny. 1/A, H-1117 Budapest, Hungary; email: zaray@ludens.elte.hu
AB  - Investigations were performed along the Danube river at Budapest (Hungary) by collecting water and sediment samples simultaneously for 1 year in order to clarify the possible hazard of selected acidic pharmaceuticals (ibuprofen, naproxen, ketoprofen, and diclofenac) on the water supply used for the production of drinking water by bank filtration In the case of water samples, the sample preparation procedure included solid phase extraction (SPE). meanwhile, in the case of sediment samples, microwave-assisted extraction (MAE) followed by dispersive matrix extraction (DME) for pre-cleaning as well as SPE for enrichment The quantification was carried out using gas chromatography-mass spectrometry (GC-MS) The calculated recoveries were 97-99% (+/- 7%) for the water and 95-103% (+/- 12%) for the sediment samples In the river water, ketoprofen concentration was always below the limit of quantification (LOQ) level, ibuprofen, naproxen and diclofenac could be quantified in the range of 8-50, 2-30. 7-90 ng/L In sediments, only naproxen and diclofenac were found in the range of 2-20 and 5-38 ng/g, respectively According to the obtained results, the concentration ratios of the two phases linearly depended on the total organic carbon content (TOC) of the sediments at each sampling date The linear regressions were 0 925 and 0 946 for naproxen and diclofenac, respectively (C) 2010 Published by Elsevier B.V
LA  - English
DB  - MTMT
ER  -