@article{MTMT:1592975,
	title = {A new sample preparation method for determination of acidic drugs in sewage sludge applying microwave assisted solvent extraction followed by gas chromatography-mass spectrometry},
	url = {https://m2.mtmt.hu/api/publication/1592975},
	author = {Dobor, József and Oltiné Varga, Margit and Yao, J and Chen, HL and Palko, G and Záray, Gyula},
	doi = {10.1016/j.microc.2009.08.007},
	journal-iso = {MICROCHEM J},
	journal = {MICROCHEMICAL JOURNAL},
	volume = {94},
	unique-id = {1592975},
	issn = {0026-265X},
	abstract = {This paper presents a new sample preparation procedure for determination of selected acidic pharmaceuticals (ibuprofen, naproxen, ketoprofen, and diclofenac) in sewage sludge using microwave assisted solvent extraction, dispersive matrix extraction (DME) followed by the conventionally applied solid phase extraction (SPE), derivatization. and gas chromatography-mass spectrometry. The recoveries calculated from analytical data of spiked sludge samples changed in the range of 80-105%+/- 15% for the four pharmaceuticals in mixed and activated sludge depending on the efficiency of the clean-up procedure. The measured concentration values of ibuprofen and naproxen were identical in the mixed and the activated sludge samples. However, ketoprofen and diclofenac showed about twice as high concentration in activated sludge than in the mixed one independently of the applied extraction method. The typical concentration ranges of ibuprofen, naproxen, ketoprofen and diclofenac in sewage sludge were 10-30 ng/g, 30-50 ng/g, 50-130 ng/g, and 50-140 ng/g respectively. (C) 2009 Elsevier B.V. All rights reserved.},
	keywords = {personal care products; Gas chromatography; SOLID-PHASE EXTRACTION; WASTE-WATER; Trace-level determination; solid phase extraction; BASIC PHARMACEUTICALS; MUSK FRAGRANCES; COEFFICIENT K-D; Dispersive matrix extraction; Microwave assisted solvent extraction; Sewage sludge; LC-MS/MS; Pharmaceutical residues; RAPID-DETERMINATION; ACIDIC PHARMACEUTICALS},
	year = {2010},
	eissn = {1095-9149},
	pages = {36-41},
	orcid-numbers = {Dobor, József/0000-0003-0191-4261; Oltiné Varga, Margit/0000-0001-5132-0598; Záray, Gyula/0000-0003-2164-1176}
}

@article{MTMT:1592969,
	title = {Investigation of acidic pharmaceuticals in river water and sediment by microwave-assisted extraction and gas chromatography-mass spectrometry},
	url = {https://m2.mtmt.hu/api/publication/1592969},
	author = {Oltiné Varga, Margit and Dobor, József and Helenkar, A and Jurecska, Laura and Yao, J and Záray, Gyula},
	doi = {10.1016/j.microc.2010.02.010},
	journal-iso = {MICROCHEM J},
	journal = {MICROCHEMICAL JOURNAL},
	volume = {95},
	unique-id = {1592969},
	issn = {0026-265X},
	abstract = {Investigations were performed along the Danube river at Budapest (Hungary) by collecting water and sediment samples simultaneously for 1 year in order to clarify the possible hazard of selected acidic pharmaceuticals (ibuprofen, naproxen, ketoprofen, and diclofenac) on the water supply used for the production of drinking water by bank filtration In the case of water samples, the sample preparation procedure included solid phase extraction (SPE). meanwhile, in the case of sediment samples, microwave-assisted extraction (MAE) followed by dispersive matrix extraction (DME) for pre-cleaning as well as SPE for enrichment The quantification was carried out using gas chromatography-mass spectrometry (GC-MS) The calculated recoveries were 97-99% (+/- 7%) for the water and 95-103% (+/- 12%) for the sediment samples In the river water, ketoprofen concentration was always below the limit of quantification (LOQ) level, ibuprofen, naproxen and diclofenac could be quantified in the range of 8-50, 2-30. 7-90 ng/L In sediments, only naproxen and diclofenac were found in the range of 2-20 and 5-38 ng/g, respectively According to the obtained results, the concentration ratios of the two phases linearly depended on the total organic carbon content (TOC) of the sediments at each sampling date The linear regressions were 0 925 and 0 946 for naproxen and diclofenac, respectively (C) 2010 Published by Elsevier B.V},
	keywords = {RESIDUES; QUANTIFICATION; sediment; SLUDGE; SOLID-PHASE EXTRACTION; WASTE-WATER; GC-MS; Trace-level determination; BASIC PHARMACEUTICALS; LC-MS/MS; SEWAGE WATER; AQUEOUS SAMPLES; Microwave assisted extraction; Pharmaceutical residues},
	year = {2010},
	eissn = {1095-9149},
	pages = {353-358},
	orcid-numbers = {Oltiné Varga, Margit/0000-0001-5132-0598; Dobor, József/0000-0003-0191-4261; Záray, Gyula/0000-0003-2164-1176}
}