@article{MTMT:2512463,
	title = {Volatile Glycosides from the Leaves of Morus alba with a Potential Contribution to the Complex Anti-diabetic Activity},
	url = {https://m2.mtmt.hu/api/publication/2512463},
	author = {Hunyadi, Attila and Herke, I and Veres, Katalin and Erdei, Anna and Simon, András and Tóth, Gábor},
	doi = {10.1177/1934578x1400900201},
	journal-iso = {NAT PROD COMMUN},
	journal = {NATURAL PRODUCT COMMUNICATIONS},
	volume = {9},
	unique-id = {2512463},
	issn = {1934-578X},
	abstract = {The leaves and root bark of Morus alba, the white mulberry tree, 
		are well-known traditional medicines for the treatment of type 
		II diabetes. Several different
		types of constituents have been suggested to be responsible for 
		the anti-diabetic activity of mulberry drugs, such as 
		iminosugars, flavonoids and other phenolic
		compounds, glycopeptides and ecdysteroids. Our group recently 
		suggested that a volatile-oil like fraction of the hot water 
		extract of M. alba leaves, containing
		several phenyl-propane derivatives, can increase the glucose 
		consumption of adipocytes. Here we report the isolation of three 
		glycosylated volatile constituents
		from mulberry leaves, two megastigmane derivatives along with 
		the β-D-glucoside of eugenol. Furthermore, a commercially 
		available mixture of probiotic
		bacteria was assessed to study the effect of the intestinal 
		flora on the megastigmane derivatives. Significant amounts of 
		the aglycons of both compounds were
		liberated, suggesting that these compounds can be metabolized in 
		the large intestines and absorbed without the sugar moiety after 
		the consumption of a
		traditional mulberry tea. Based on literature data, both the 
		glycosides and their aglycons have a potential contribution to 
		the beneficial effects of mulberry
		leaves in type 2 diabetes.},
	year = {2014},
	eissn = {1555-9475},
	pages = {145-147},
	orcid-numbers = {Hunyadi, Attila/0000-0003-0074-3472; Veres, Katalin/0000-0001-7108-3622}
}

@article{MTMT:2102858,
	title = {In vitro Anti‐diabetic Activity and Chemical Characterization of an Apolar Fraction of Morus alba Leaf Water Extract},
	url = {https://m2.mtmt.hu/api/publication/2102858},
	author = {Hunyadi, Attila and Veres, Katalin and Dankó, Balázs Ödön and Kele, Zoltán and Wéber, Edit and Hetényi, Anasztázia and Zupkó, István and Hsieh, TJ},
	doi = {10.1002/ptr.4803},
	journal-iso = {PHYTOTHER RES},
	journal = {PHYTOTHERAPY RESEARCH},
	volume = {27},
	unique-id = {2102858},
	issn = {0951-418X},
	abstract = {The tea from the white mulberry (Morus alba L.) leaf is a worldwide known traditional medicine of type II diabetes. Here, we report the investigation of the dichloromethane-soluble fraction obtained in a 0.24% m/m yield from the hot water extract of mulberry leaves. A significant, dose-dependent activity was found by means of the 24-h glucose consumption of fully differentiated adipocytes both in the absence and presence of insulin. The fraction was characterized by HPLC-DAD, GC-MS and GC-FID. The main constituent (40.3% by means of GC-FID) was isolated and identified as loliolide by EIMS, HRESIMS and NMR spectroscopy. In the active fraction benzyl alcohol, ethyl benzoate, t-cinnamic acid, p-hydroxyacetophenone, t-coniferyl alcohol and synapil alcohol were also identified by GC-MS and quantified by GC-FID (0.7, 1.3, 1.5, 2.9, 7.5 and 2.6%, respectively). Copyright (c) 2012 John Wiley & Sons, Ltd.},
	keywords = {Diabetes; BLOOD-GLUCOSE; CONSTITUENTS; Chemistry, Medicinal; Morus alba; mulberry; anti-diabetic; loliolide; loliolide},
	year = {2013},
	eissn = {1099-1573},
	pages = {847-851},
	orcid-numbers = {Hunyadi, Attila/0000-0003-0074-3472; Veres, Katalin/0000-0001-7108-3622; Kele, Zoltán/0000-0002-4401-0302; Wéber, Edit/0000-0002-5904-0619; Hetényi, Anasztázia/0000-0001-8080-6992; Zupkó, István/0000-0003-3243-5300}
}