@article{MTMT:2326115,
	title = {Drosophila Nimrod proteins bind bacteria},
	url = {https://m2.mtmt.hu/api/publication/2326115},
	author = {Zsámboki, János and Csordás, Gábor and Honti, Viktor and Pintér, Lajos and Bajusz, Izabella and Galgóczi, László Norbert and Andó, István and Kurucz, Judit Éva},
	doi = {10.2478/s11535-013-0183-4},
	journal-iso = {CENT EUR J BIOL},
	journal = {CENTRAL EUROPEAN JOURNAL OF BIOLOGY},
	volume = {8},
	unique-id = {2326115},
	issn = {1895-104X},
	abstract = {Engulfment of foreign particles by phagocytes is initiated by the engagement of phagocytic receptors. We have previously reported that NimC1 is involved in the phagocytosis of bacteria in Drosophila melanogaster. We have identified a family of genes, the Nimrod gene superfamily, encoding characteristic NIM domain containing structural homologues of NimC1. In this work we studied the bacterium-binding properties of the Nimrod proteins by using a novel immunofluorescencebased flow cytometric assay. This method proved to be highly reproducible and suitable for investigations of the bacteriumbinding capacities of putative phagocytosis receptors. We found that NimC1, NimA, NimB1 and NimB2 bind bacteria significantly but differently. In this respect they are similar to other NIM domain containing receptors Eater and Draper.},
	year = {2013},
	eissn = {1644-3632},
	pages = {633-645},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839; Galgóczi, László Norbert/0000-0002-6976-8910; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1921818,
	title = {Integrin beta nu-mediated Phagocytosis of Apoptotic Cells in Drosophila Embryos},
	url = {https://m2.mtmt.hu/api/publication/1921818},
	author = {Nagaosa, K and Okada, R and Nonaka, S and Takeuchi, K and Fujita, Y and Miyasaka, T and Manaka, J and Andó, István and Nakanishi, Y},
	doi = {10.1074/jbc.M110.204503},
	journal-iso = {J BIOL CHEM},
	journal = {JOURNAL OF BIOLOGICAL CHEMISTRY},
	volume = {286},
	unique-id = {1921818},
	issn = {0021-9258},
	abstract = {To identify molecules that play roles in the clearance of apoptotic cells by Drosophila phagocytes, we examined a series of monoclonal antibodies raised against larval hemocytes for effects on phagocytosis in vitro. One antibody that inhibited phagocytosis recognized terribly reduced optic lobes (Trol), a core protein of the perlecan-type proteoglycan, and the level of phagocytosis in embryos of a Trol-lacking fly line was lower than in a control line. The treatment of a hemocyte cell line with a recombinant Trol protein containing the amino acid sequence RGD augmented the phosphorylation of focal adhesion kinase, a hallmark of integrin activation. A loss of integrin beta nu, one of the two beta subunits of Drosophila integrin, brought about a reduction in the level of apoptotic cell clearance in embryos. The presence of integrin beta nu at the surface of embryonic hemocytes was confirmed, and forced expression of integrin beta nu in hemocytes of an integrin beta nu-lacking fly line recovered the defective phenotype of phagocytosis. Finally, the level of phagocytosis in a fly line that lacks both integrin beta nu and Draper, another receptor required for the phagocytosis of apoptotic cells, was lower than that in a fly line lacking either protein. We suggest that integrin beta nu serves as a phagocytosis receptor responsible for the clearance of apoptotic cells in Drosophila, independent of Draper.},
	year = {2011},
	eissn = {1083-351X},
	pages = {25770-25777},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1921048,
	title = {Cell lineage tracing reveals the plasticity of the hemocyte lineages and of the hematopoietic compartments in drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/1921048},
	author = {Honti, Viktor and Csordás, Gábor and Márkus, Róbert and Kurucz, Judit Éva and Jankovics, Ferenc and Andó, István},
	doi = {10.1016/j.molimm.2010.04.017},
	journal-iso = {MOL IMMUNOL},
	journal = {MOLECULAR IMMUNOLOGY},
	volume = {47},
	unique-id = {1921048},
	issn = {0161-5890},
	keywords = {Animals; Immunity, Innate; Immunity, Cellular; Receptors, Scavenger/genetics; Hemocytes/cytology/*physiology; *Hematopoiesis; Drosophila melanogaster/embryology/*immunology; Drosophila Proteins/genetics; *Cell Lineage},
	year = {2010},
	eissn = {1872-9142},
	pages = {1997-2004},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1920812,
	title = {In vivo detection of lamellocytes in Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/1920812},
	author = {Honti, Viktor and Kurucz, Judit Éva and Csordás, Gábor and Laurinyecz, Barbara and Márkus, Róbert and Andó, István},
	doi = {10.1016/j.imlet.2009.08.004},
	journal-iso = {IMMUNOL LETT},
	journal = {IMMUNOLOGY LETTERS},
	volume = {126},
	unique-id = {1920812},
	issn = {0165-2478},
	keywords = {Animals; Cell Differentiation; Mutagenesis, Insertional; Fluorescent Antibody Technique, Indirect; Green Fluorescent Proteins/genetics/metabolism; DNA Transposable Elements/genetics; Larva/genetics/metabolism; Hemocytes/cytology/*metabolism; Drosophila melanogaster/*genetics/metabolism; Drosophila Proteins/*genetics},
	year = {2009},
	eissn = {1879-0542},
	pages = {83-84},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839; Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1920757,
	title = {Sessile hemocytes as a hematopoietic compartment in drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/1920757},
	author = {Márkus, Róbert and Laurinyecz, Barbara and Kurucz, Judit Éva and Honti, Viktor and Bajusz, Izabella and Sipos, Botond and Somogyi, Kálmán and Kronhamn, J and Hultmark, D and Andó, István},
	doi = {10.1073/pnas.0801766106},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {106},
	unique-id = {1920757},
	issn = {0027-8424},
	year = {2009},
	eissn = {1091-6490},
	pages = {4805-4809},
	orcid-numbers = {Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1918046,
	title = {Evolution of Genes and Repeats in the Nimrod Superfamily},
	url = {https://m2.mtmt.hu/api/publication/1918046},
	author = {Somogyi, Kálmán and Sipos, Botond and Pénzes, Zsolt and Kurucz, Judit Éva and Zsámboki, János and Hultmark, D and Andó, István},
	doi = {10.1093/molbev/msn180},
	journal-iso = {MOL BIOL EVOL},
	journal = {MOLECULAR BIOLOGY AND EVOLUTION},
	volume = {25},
	unique-id = {1918046},
	issn = {0737-4038},
	abstract = {The recently identified Nimrod superfamily is characterized by the presence of a special type of EGF repeat, the NIM repeat, located right after a typical CCXGY/W amino acid motif. On the basis of structural features, nimrod genes can be divided into three types. The proteins encoded by Draper-type genes have an EMI domain at the N-terminal part and only one copy of the NIM motif, followed by a variable number of EGF-like repeats. The products of Nimrod B-type and Nimrod C-type genes (including the eater gene) have different kinds of N-terminal domains, and lack EGF-like repeats but contain a variable number of NIM repeats. Draper and Nimrod C-type (but not Nimrod B-type) proteins carry a transmembrane domain. Several members of the superfamily were claimed to function as receptors in phagocytosis and/or binding of bacteria, which indicates an important role in the cellular immunity and the elimination of apoptotic cells. In this paper, the evolution of the Nimrod superfamily is studied with various methods on the level of genes and repeats. A hypothesis is presented in which the NIM repeat, along with the EMI domain, emerged by structural reorganizations at the end of an EGF-like repeat chain, suggesting a mechanism for the formation of novel types of repeats. The analyses revealed diverse evolutionary patterns in the sequences containing multiple NIM repeats. Although in the Nimrod B and Nimrod C proteins show characteristics of independent evolution, many internal NIM repeats in Eater sequences seem to have undergone concerted evolution. An analysis of the nimrod genes has been performed using phylogenetic and other methods and an evolutionary scenario of the origin and diversification of the Nimrod superfamily is proposed. Our study presents an intriguing example how the evolution of multigene families may contribute to the complexity of the innate immune response.},
	year = {2008},
	eissn = {1537-1719},
	pages = {2337-2347},
	orcid-numbers = {Pénzes, Zsolt/0000-0003-0447-5997; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1915261,
	title = {Definition of Drosophila hemocyte subsets by cell-type specific antigens},
	url = {https://m2.mtmt.hu/api/publication/1915261},
	author = {Kurucz, Judit Éva and Váczi, Balázs and Márkus, Róbert and Laurinyecz, Barbara and Vilmos, Péter and Zsámboki, János and Csorba, Kinga and Gateff, E and Hultmark, D and Andó, István},
	doi = {10.1556/ABiol.58.2007.Suppl.8},
	journal-iso = {ACTA BIOL HUNG},
	journal = {ACTA BIOLOGICA HUNGARICA (1983-2018)},
	volume = {58},
	unique-id = {1915261},
	issn = {0236-5383},
	abstract = {We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. Oil the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmalocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged ill four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocyles.},
	year = {2007},
	eissn = {1588-256X},
	pages = {95-111},
	orcid-numbers = {Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1915010,
	title = {Nimrod, a Putative Phagocytosis Receptor With Egf Repeats in Drosophila Plasmatocytes},
	url = {https://m2.mtmt.hu/api/publication/1915010},
	author = {Kurucz, Judit Éva and Márkus, Róbert and Zsámboki, János and Medzihradszky F., Katalin and Darula, Zsuzsanna and Vilmos, Péter and Udvardy, Andor and Krausz, Ildikó and Lukacsovich, Tamás and Gateff, E and Zettervall, CJ and Hultmark, D and Andó, István},
	doi = {10.1016/j.cub.2007.02.041},
	journal-iso = {CURR BIOL},
	journal = {CURRENT BIOLOGY},
	volume = {17},
	unique-id = {1915010},
	issn = {0960-9822},
	year = {2007},
	eissn = {1879-0445},
	pages = {649-654},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1786592,
	title = {Expression pattern of Filamin-240 in Drosophila blood cells},
	url = {https://m2.mtmt.hu/api/publication/1786592},
	author = {Rus, Florentina and Kurucz, Judit Éva and Márkus, Róbert and Sinenko, SA and Laurinyecz, Barbara and Pataki, Andrea Csilla and Gausz, János and Hegedűs, Zoltán and Udvardy, Andor and Hultmark, D and Andó, István},
	doi = {10.1016/j.modgep.2006.03.005},
	journal-iso = {GENE EXPR PATTERNS},
	journal = {GENE EXPRESSION PATTERNS},
	volume = {6},
	unique-id = {1786592},
	issn = {1567-133X},
	keywords = {Animals; Female; TISSUE DISTRIBUTION; PHENOTYPE; PROTEIN ISOFORMS; ARTICLE; DROSOPHILA; HEMOCYTES; Cell Differentiation; priority journal; controlled study; nonhuman; animal tissue; animal cell; larva; Protein Binding; immune system; Western blotting; Animals, Genetically Modified; Gene Expression Profiling; PROTEIN FUNCTION; unclassified drug; protein expression; DNA, Complementary; Blood cells; encapsulation; in vivo study; blood cell; protein domain; TRANSGENE; immunofluorescence test; HOMOZYGOSITY; FILAMIN; protein motif; MUTANT; Contractile proteins; Microfilament Proteins; Vespoidea; Leptopilina boulardi; Wasps; larval development; insect development; filamin 240; Lamellocyte; Immune induction; Hemocyte; Blood cell development; Actin network},
	year = {2006},
	eissn = {1872-7298},
	pages = {928-934},
	orcid-numbers = {Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1913892,
	title = {Sterile wounding is a minimal and sufficient trigger for a cellular immune response in Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/1913892},
	author = {Márkus, Róbert and Kurucz, Judit Éva and Rus, Florentina and Andó, István},
	doi = {10.1016/j.imlet.2005.03.021},
	journal-iso = {IMMUNOL LETT},
	journal = {IMMUNOLOGY LETTERS},
	volume = {101},
	unique-id = {1913892},
	issn = {0165-2478},
	year = {2005},
	eissn = {1879-0542},
	pages = {108-111},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1913913,
	title = {Drosophila melanogaster Rac2 is necessary for a proper cellular immune response},
	url = {https://m2.mtmt.hu/api/publication/1913913},
	author = {Williams, MJ and Andó, István and Hultmark, D},
	doi = {10.1111/j.1365-2443.2005.00883.x},
	journal-iso = {GENES CELLS},
	journal = {GENES TO CELLS},
	volume = {10},
	unique-id = {1913913},
	issn = {1356-9597},
	year = {2005},
	eissn = {1365-2443},
	pages = {813-823},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1913536,
	title = {A directed screen for genes involved in Drosophila blood cell activation},
	url = {https://m2.mtmt.hu/api/publication/1913536},
	author = {Zettervall, CJ and Anderl, I and Williams, MJ and Palmer, R and Kurucz, Judit Éva and Andó, István and Hultmark, D},
	doi = {10.1073/pnas.0403789101},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {101},
	unique-id = {1913536},
	issn = {0027-8424},
	year = {2004},
	eissn = {1091-6490},
	pages = {14192-14197},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1912854,
	title = {Analysis of Ras-induced overproliferation in Drosophila hemocytes},
	url = {https://m2.mtmt.hu/api/publication/1912854},
	author = {Asha, H and Nagy, István and Kovacs, G and Stetson, D and Andó, István and Dearolf, CR},
	journal-iso = {GENETICS},
	journal = {GENETICS},
	volume = {163},
	unique-id = {1912854},
	issn = {0016-6731},
	year = {2003},
	eissn = {1943-2631},
	pages = {203-215},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1912851,
	title = {Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila},
	url = {https://m2.mtmt.hu/api/publication/1912851},
	author = {Kurucz, Judit Éva and Zettervall, CJ and Sinka, Rita and Vilmos, Péter and Pivarcsi, A and Ekengren, S and Hegedűs, Zoltán and Andó, István and Hultmark, D},
	doi = {10.1073/pnas.0436940100},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {100},
	unique-id = {1912851},
	issn = {0027-8424},
	year = {2003},
	eissn = {1091-6490},
	pages = {2622-2627},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184; Andó, István/0000-0002-4648-9396}
}