@article{MTMT:1921481,
	title = {A conserved gene cluster as a putative functional unit in insect innate immunity},
	url = {https://m2.mtmt.hu/api/publication/1921481},
	author = {Somogyi, Kálmán and Sipos, Botond and Pénzes, Zsolt and Andó, István},
	doi = {10.1016/j.febslet.2010.10.014},
	journal-iso = {FEBS LETT},
	journal = {FEBS LETTERS},
	volume = {584},
	unique-id = {1921481},
	issn = {0014-5793},
	abstract = {The Nimrod gene superfamily is an important component of the innate immune response. The majority of its member genes are located in close proximity within the Drosophila melanogaster genome and they lie in a larger conserved cluster ("Nimrod cluster"), made up of non-related groups (families, superfamilies) of genes. This cluster has been a part of the Arthropod genomes for about 300-350 million years. The available data suggest that the Nimrod cluster is a functional module of the insect innate immune response. (C) 2010 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.},
	year = {2010},
	eissn = {1873-3468},
	pages = {4375-4378},
	orcid-numbers = {Pénzes, Zsolt/0000-0003-0447-5997; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1920812,
	title = {In vivo detection of lamellocytes in Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/1920812},
	author = {Honti, Viktor and Kurucz, Judit Éva and Csordás, Gábor and Laurinyecz, Barbara and Márkus, Róbert and Andó, István},
	doi = {10.1016/j.imlet.2009.08.004},
	journal-iso = {IMMUNOL LETT},
	journal = {IMMUNOLOGY LETTERS},
	volume = {126},
	unique-id = {1920812},
	issn = {0165-2478},
	keywords = {Animals; Cell Differentiation; Mutagenesis, Insertional; Fluorescent Antibody Technique, Indirect; Green Fluorescent Proteins/genetics/metabolism; DNA Transposable Elements/genetics; Larva/genetics/metabolism; Hemocytes/cytology/*metabolism; Drosophila melanogaster/*genetics/metabolism; Drosophila Proteins/*genetics},
	year = {2009},
	eissn = {1879-0542},
	pages = {83-84},
	orcid-numbers = {Csordás, Gábor/0000-0001-6871-6839; Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1918046,
	title = {Evolution of Genes and Repeats in the Nimrod Superfamily},
	url = {https://m2.mtmt.hu/api/publication/1918046},
	author = {Somogyi, Kálmán and Sipos, Botond and Pénzes, Zsolt and Kurucz, Judit Éva and Zsámboki, János and Hultmark, D and Andó, István},
	doi = {10.1093/molbev/msn180},
	journal-iso = {MOL BIOL EVOL},
	journal = {MOLECULAR BIOLOGY AND EVOLUTION},
	volume = {25},
	unique-id = {1918046},
	issn = {0737-4038},
	abstract = {The recently identified Nimrod superfamily is characterized by the presence of a special type of EGF repeat, the NIM repeat, located right after a typical CCXGY/W amino acid motif. On the basis of structural features, nimrod genes can be divided into three types. The proteins encoded by Draper-type genes have an EMI domain at the N-terminal part and only one copy of the NIM motif, followed by a variable number of EGF-like repeats. The products of Nimrod B-type and Nimrod C-type genes (including the eater gene) have different kinds of N-terminal domains, and lack EGF-like repeats but contain a variable number of NIM repeats. Draper and Nimrod C-type (but not Nimrod B-type) proteins carry a transmembrane domain. Several members of the superfamily were claimed to function as receptors in phagocytosis and/or binding of bacteria, which indicates an important role in the cellular immunity and the elimination of apoptotic cells. In this paper, the evolution of the Nimrod superfamily is studied with various methods on the level of genes and repeats. A hypothesis is presented in which the NIM repeat, along with the EMI domain, emerged by structural reorganizations at the end of an EGF-like repeat chain, suggesting a mechanism for the formation of novel types of repeats. The analyses revealed diverse evolutionary patterns in the sequences containing multiple NIM repeats. Although in the Nimrod B and Nimrod C proteins show characteristics of independent evolution, many internal NIM repeats in Eater sequences seem to have undergone concerted evolution. An analysis of the nimrod genes has been performed using phylogenetic and other methods and an evolutionary scenario of the origin and diversification of the Nimrod superfamily is proposed. Our study presents an intriguing example how the evolution of multigene families may contribute to the complexity of the innate immune response.},
	year = {2008},
	eissn = {1537-1719},
	pages = {2337-2347},
	orcid-numbers = {Pénzes, Zsolt/0000-0003-0447-5997; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1915261,
	title = {Definition of Drosophila hemocyte subsets by cell-type specific antigens},
	url = {https://m2.mtmt.hu/api/publication/1915261},
	author = {Kurucz, Judit Éva and Váczi, Balázs and Márkus, Róbert and Laurinyecz, Barbara and Vilmos, Péter and Zsámboki, János and Csorba, Kinga and Gateff, E and Hultmark, D and Andó, István},
	doi = {10.1556/ABiol.58.2007.Suppl.8},
	journal-iso = {ACTA BIOL HUNG},
	journal = {ACTA BIOLOGICA HUNGARICA (1983-2018)},
	volume = {58},
	unique-id = {1915261},
	issn = {0236-5383},
	abstract = {We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. Oil the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmalocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged ill four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocyles.},
	year = {2007},
	eissn = {1588-256X},
	pages = {95-111},
	orcid-numbers = {Laurinyecz, Barbara/0000-0003-0620-2239; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1915010,
	title = {Nimrod, a Putative Phagocytosis Receptor With Egf Repeats in Drosophila Plasmatocytes},
	url = {https://m2.mtmt.hu/api/publication/1915010},
	author = {Kurucz, Judit Éva and Márkus, Róbert and Zsámboki, János and Medzihradszky F., Katalin and Darula, Zsuzsanna and Vilmos, Péter and Udvardy, Andor and Krausz, Ildikó and Lukacsovich, Tamás and Gateff, E and Zettervall, CJ and Hultmark, D and Andó, István},
	doi = {10.1016/j.cub.2007.02.041},
	journal-iso = {CURR BIOL},
	journal = {CURRENT BIOLOGY},
	volume = {17},
	unique-id = {1915010},
	issn = {0960-9822},
	year = {2007},
	eissn = {1879-0445},
	pages = {649-654},
	orcid-numbers = {Andó, István/0000-0002-4648-9396}
}

@article{MTMT:1912851,
	title = {Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila},
	url = {https://m2.mtmt.hu/api/publication/1912851},
	author = {Kurucz, Judit Éva and Zettervall, CJ and Sinka, Rita and Vilmos, Péter and Pivarcsi, A and Ekengren, S and Hegedűs, Zoltán and Andó, István and Hultmark, D},
	doi = {10.1073/pnas.0436940100},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {100},
	unique-id = {1912851},
	issn = {0027-8424},
	year = {2003},
	eissn = {1091-6490},
	pages = {2622-2627},
	orcid-numbers = {Sinka, Rita/0000-0003-4040-4184; Andó, István/0000-0002-4648-9396}
}