TY - JOUR AU - Schneider, Miklós AU - Borgulya, G AU - Seres, A AU - Nagy, Zoltán Zsolt AU - Németh, János Tibor TI - Central corneal thickness measurements with optical coherence tomography and ultrasound pachymetry in healthy subjects and in patients after photorefractive keratectomy. JF - EUROPEAN JOURNAL OF OPHTHALMOLOGY J2 - EUR J OPHTHALMOL VL - 19 PY - 2009 IS - 2 SP - 180 EP - 187 PG - 8 SN - 1120-6721 UR - https://m2.mtmt.hu/api/publication/1697292 ID - 1697292 AB - PURPOSE: To compare central corneal thickness measurements made using two different methods, optical coherence tomography (OCT) and ultrasound pachymetry, applied both in normal eyes and in eyes on which photorefractive keratectomy (PRK) had been performed. A second objective was to assess the intrasession variability of OCT measurements. METHODS: In this prospective study, central corneal thickness was measured in 20 normal subjects (normal group) and in 20 PRK patients using the StratusOCT instrument model 3000 (Carl Zeiss Meditec), and also with an ultrasound pachymeter. Five OCT measurements were performed using the Fast Macular Thickness protocol. Corneal thickness data were obtained with the Scan Profile analysis protocol. The OCT measurement results were compared with the mean value of three ultrasound pachymetry measurements for the same eye. RESULTS: The pachymetry-OCT correlation coefficients were 0.96 and 0.97 in the normal and PRK groups, respectively (p=0.14). Neither linear regression nor Bland-Altmann analysis revealed any significant systematic measurement error. Intrasession standard deviations in the normal and PRK groups were 4.9 microm and 3.8 microm, respectively. CONCLUSIONS: Noncontact central corneal thickness measurements made using the StratusOCT instrument are accurate and reproducible, both in normal subjects and in post-PRK patients. The instrument system does not need any modifications to correctly detect and measure the center of the cornea. LA - English DB - MTMT ER -