@article{MTMT:3391890, title = {Two-photon excitation and emission spectra of the green fluorescent protein variants ECFP, EGFP and EYFP}, url = {https://m2.mtmt.hu/api/publication/3391890}, author = {Spiess, E and Bestvater, F and Heckel-Pompey, A and Tóth, Katalin and Hacker, M and Stobrawa, G and Feurer, T and Wotzlaw, C and Berchner-Pfannschmidt, U and Porwol, T and Acker, H}, doi = {10.1111/j.1365-2818.2005.01437.x}, journal-iso = {J MICROSC-OXFORD}, journal = {JOURNAL OF MICROSCOPY-OXFORD}, volume = {217}, unique-id = {3391890}, issn = {0022-2720}, year = {2005}, eissn = {1365-2818}, pages = {200-204} } @article{MTMT:109457, title = {Calcium dynamics of cortical astrocytic networks in vivo}, url = {https://m2.mtmt.hu/api/publication/109457}, author = {Hirase, H and Qian, L and Barthó, Péter and Buzsáki, György}, doi = {10.1371/journal.pbio.0020096}, journal-iso = {PLOS BIOL}, journal = {PLOS BIOLOGY}, volume = {2}, unique-id = {109457}, issn = {1544-9173}, year = {2004}, eissn = {1545-7885}, pages = {494-499} } @article{MTMT:109502, title = {Distance-dependent scaling of calcium transients evoked by backpropagating spikes and synaptic activity in dendrites of hippocampal interneurons}, url = {https://m2.mtmt.hu/api/publication/109502}, author = {Rózsa J., Balázs and Zelles, Tibor and Vizi, E. Szilveszter and Lendvai, Balázs}, doi = {10.1523/JNEUROSCI.3906-03.2004}, journal-iso = {J NEUROSCI}, journal = {JOURNAL OF NEUROSCIENCE}, volume = {24}, unique-id = {109502}, issn = {0270-6474}, year = {2004}, eissn = {1529-2401}, pages = {661-670}, orcid-numbers = {Zelles, Tibor/0000-0002-0357-0469; Vizi, E. Szilveszter/0000-0002-9557-4597} } @article{MTMT:1616468, title = {Impaired regulation of synaptic strength in hippocampal neurons from GluR1-deficient mice}, url = {https://m2.mtmt.hu/api/publication/1616468}, author = {Andrásfalvy, Bertalan and Smith, MA and Borchardt, T and Sprengel, R and Magee, JC}, doi = {10.1113/jphysiol.2003.045575}, journal-iso = {J PHYSIOL-LONDON}, journal = {JOURNAL OF PHYSIOLOGY-LONDON}, volume = {552}, unique-id = {1616468}, issn = {0022-3751}, abstract = {Neurons of the central nervous system (CNS) exhibit a variety of forms of synaptic plasticity, including associative long-term potentiation and depression (LTP/D), homeostatic activity-dependent scaling and distance-dependent scaling. Regulation of synaptic neurotransmitter receptors is currently thought to be a common mechanism amongst many of these forms of plasticity. In fact, glutamate receptor 1 (GluR1 or GluRA) subunits containing L-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors have been shown to be required for several forms of hippocampal LTP and a particular hippocampal-dependent learning task. Because of this importance in associative plasticity, we sought to examine the role of these receptors in other forms of synaptic plasticity in the hippocampus. To do so, we recorded from the apical dendrites of hippocampal CA1 pyramidal neurons in mice lacking the GluR1 subunit (GluR1 -/-). Here we report data from outside-out patches that indicate GluR1-containing receptors are essential to the extrasynaptic population of AMPA receptors, as this pool was nearly empty in the GluR1 -/- mice. Additionally, these receptors appear to be a significant component of the synaptic glutamate receptor pool because the amplitude of spontaneous synaptic currents recorded at the site of input and synaptic AMPA receptor currents evoked by focal glutamate uncaging were both substantially reduced in these mice. Interestingly, the impact on synaptic weight was greatest at distant synapses such that the normal distance-dependent synaptic scaling used by these cells to counter dendritic attenuation was lacking in GluR1 -/- mice. Together the data suggest that the highly regulated movement of GluR1-containing AMPA receptors between extrasynaptic and synaptic receptor pools is critically involved in establishing two functionally diverse forms of synaptic plasticity: LTP and distance-dependent scaling.}, keywords = {Animals; MICE; KINETICS; Hippocampus/cytology/*physiology; Mice, Inbred C57BL; Pyramidal Cells/*physiology; Synapses/*physiology; Patch-Clamp Techniques; Neuronal Plasticity/physiology; Long-Term Potentiation/physiology; Mice, Mutant Strains; Receptors, AMPA/*genetics/*metabolism}, year = {2003}, eissn = {1469-7793}, pages = {35-45} } @article{MTMT:1442913, title = {Calcium microdomains in aspiny dendrites.}, url = {https://m2.mtmt.hu/api/publication/1442913}, author = {Goldberg, JH and Tamás, Gábor and Aronov, D and Yuste, R}, doi = {10.1016/S0896-6273(03)00714-1}, journal-iso = {NEURON}, journal = {NEURON}, volume = {40}, unique-id = {1442913}, issn = {0896-6273}, abstract = {Dendritic spines receive excitatory synapses and serve as calcium compartments, which appear to be necessary for input-specific synaptic plasticity. Dendrites of GABAergic interneurons have few or no spines and thus do not possess a clear morphological basis for synapse-specific compartmentalization. We demonstrate using two-photon calcium imaging that activation of single synapses on aspiny dendrites of neocortical fast spiking (FS) interneurons creates highly localized calcium microdomains, often restricted to less than 1 microm of dendritic space. We confirm using ultrastructural reconstruction of imaged dendrites the absence of any morphological basis for this compartmentalization and show that it is dependent on the fast kinetics of calcium-permeable (CP) AMPA receptors and fast local extrusion via the Na+/Ca2+ exchanger. Because aspiny dendrites throughout the CNS express CP-AMPA receptors, we propose that CP-AMPA receptors mediate a spine-free mechanism of input-specific calcium compartmentalization.}, keywords = {Animals; MICE; Excitatory Postsynaptic Potentials/physiology; Microscopy, Electron; Mice, Inbred C57BL; Interneurons/*physiology/ultrastructure; Action Potentials/physiology; Models, Neurological; Indicators and Reagents; Synaptic Transmission/physiology; Cell Compartmentation/physiology; Calcium Signaling/*physiology; Synaptic Membranes/physiology/ultrastructure; Sodium-Calcium Exchanger/physiology; Receptors, AMPA/*physiology; Neocortex/*physiology/ultrastructure; Fluorescent Dyes/diagnostic use; Calcium/metabolism/physiology; Dendrites/*physiology/ultrastructure}, year = {2003}, eissn = {1097-4199}, pages = {807-821}, orcid-numbers = {Tamás, Gábor/0000-0002-7905-6001} } @article{MTMT:108830, title = {Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo}, url = {https://m2.mtmt.hu/api/publication/108830}, author = {Lendvai, Balázs and Stern, EA and Chen, B and Svoboda, K}, doi = {10.1038/35009107}, journal-iso = {NATURE}, journal = {NATURE}, volume = {404}, unique-id = {108830}, issn = {0028-0836}, year = {2000}, eissn = {1476-4687}, pages = {876-881} }