https://m2.mtmt.hu/ hun 2026-06-13 20:51 true true 1 1 1 1 100 1 1 DESC publishedYear false ASC firstAuthor true ASC title true JournalArticle 3322273 VALIDATED true Laboratory for Neuron Glia Circuit, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Hirosawa 2-1, Japan Neuronal Networks Group, College of Medical and Dental Sciences, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom Laboratory for Behavioral Genetics, RIKEN Brain Science Institute, Wako, Japan Department of Biochemistry, Kitasato University School of Medicine, Sagamihara, Japan Saitama University Brain Science Institute, Saitama, Japan Export Date: 22 March 2025; Cited By: 74; Correspondence Address: H. Hirase; Laboratory for Neuron Glia Circuit, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Hirosawa 2-1, Japan; email: hirase@brain.riken.jp; CODEN: EJONE 0 2018-01-25T08:43:21.000+0000 false 3322273 2026-05-18T03:41:04.132+0000 2024-12-06T17:46:01.425+0000 2018-01-24T09:06:09.000+0000 true 10009549 Sík Attila /api/author/10009549 Author true 10009549 2025-03-22T15:53:17.657+0000 2025-03-22T15:53:17.657+0000 2024-12-06T17:46:01.598+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Shinohara, Y Hippocampal CA3 and CA2 have distinct bilateral innervation patterns to CA1 in rodents. true true /api/journal/1510 REVIEWED true false 1510 false 1510 true 0953-816X 1460-9568 Journal FOREIGN 35 5 702 710 702 9 2012 Ipsilateral and contralateral hippocampal CA3-CA1 and CA2-CA1 projections were investigated in adult male Long-Evans rats by retrograde tracing. Injection of the retrograde tracer cholera toxin subunit B in the strata oriens and radiatum of dorsal CA1 resulted in labeling of predominantly pyramidal cells in ipsilateral and contralateral CA3 and CA2. The contralateral and ipsilateral anterior-posterior extents of CA3 innervation to CA1 were similar. Fifteen to twenty per cent of the hippocampus proper cells that give rise to CA1 stratum oriens innervation were CA2 pyramidal cells, whereas CA2 cells were a mere 3% for CA1 stratum radiatum innervation. The preferred projection of CA2 pyramidal cells to the CA1 stratum oriens was also manifested in transgenic mice that express GFP under the control of the CACNG5 promoter, in which CA2 cells express high amounts of GFP. The ratios of ipsilateral to contralateral projections were compared. For the CA3-CA1 connection, we found that dorsal CA1 stratum radiatum received more ipsilateral projections whereas CA1 stratum oriens received more contralateral innervation. Interestingly, ipsilateral connections dominated for both CA2-CA1 stratum oriens and CA2-CA1 stratum radiatum. These results demonstrate that the primary intrahippocampal target of CA2 pyramidal cells is the ipsilateral CA1 stratum oriens, in contrast to CA3 cells which project more diversely to bilateral CA1 regions. Such innervation patterns may suggest differential dendritic information processing in apical and basal dendrites of CA1 pyramidal cells. 2018 806982 true true true false false NONE 2026-05-18 false true 10009549 Sík Attila /api/author/10009549 Author true 10009549 78 0 78 75 2 78 78 74 75 78 78 75 75 75 3 0 78 75 78 75 0 3 3 Q1 false false false false 2019-01-31T22:59:00.000+0000 2018-01-24T09:44:47.000+0000 1 20 0 9 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 9753519 /api/authorship/9753519 1 0.11111111 true false Shinohara Y true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 27515054 true PersonAuthorship 9753520 /api/authorship/9753520 2 0.11111111 false false Hosoya A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 27515053 true PersonAuthorship 9753521 /api/authorship/9753521 3 0.11111111 false false Yahagi K true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 27515052 true PersonAuthorship 9753522 /api/authorship/9753522 4 0.11111111 false false Ferecsko AS true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 27515051 true PersonAuthorship 9753523 /api/authorship/9753523 5 0.11111111 false false Yaguchi K true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 27515050 true PersonAuthorship 9753524 /api/authorship/9753524 6 0.11111111 false false Author 10009549 /api/author/10009549 Sík Attila true 10009549 true Sik A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 27515049 true PersonAuthorship 9753525 /api/authorship/9753525 7 0.11111111 false false Itakura M true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 27515048 true PersonAuthorship 9753526 /api/authorship/9753526 8 0.11111111 false false Takahashi M true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 27515047 true PersonAuthorship 9753527 /api/authorship/9753527 9 0.111 false true true Hirase H true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 27515046 true PublicationIdentifier 1265649 /api/publicationidentifier/1265649 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true false IDENTICAL 10.1111/j.1460-9568.2012.07993.x https://doi.org/10.1111/j.1460-9568.2012.07993.x false 1705941 true PublicationIdentifier 1265647 /api/publicationidentifier/1265647 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true false IDENTICAL 000301119000007 https://www.webofscience.com/wos/woscc/full-record/000301119000007 false 1706018 true PublicationIdentifier 1265648 /api/publicationidentifier/1265648 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true false IDENTICAL 84857995750 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84857995750 false 1706042 true PublicationIdentifier 1265650 /api/publicationidentifier/1265650 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true false IDENTICAL 22339771 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=22339771&dopt=Abstract false 1705942 true Classification 12125 /api/classification/12125 true true Keyword 12 /api/keyword/12 true 12 true Keyword 62 /api/keyword/62 true 62 true Keyword 629 /api/keyword/629 true 629 true Keyword 1547 /api/keyword/1547 true 1547 true Keyword 3428 /api/keyword/3428 true 3428 true Keyword 3461 /api/keyword/3461 true 3461 true Keyword 3497 /api/keyword/3497 true 3497 true Keyword 7927 /api/keyword/7927 true 7927 true Keyword 21379 /api/keyword/21379 true 21379 true Keyword 1008193 /api/keyword/1008193 true 1008193 true Keyword 1284917 /api/keyword/1284917 true 1284917 true Keyword 1466737 /api/keyword/1466737 true 1466737 true SjrRating 5671842 /api/sjrrating/5671842 22 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2801 /api/classificationexternal/2801 true 2801 true Q1 DIRECT true 5671842 true /api/publication/3322273 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Shinohara Y </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hosoya A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Yahagi K </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ferecsko AS </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Yaguchi K </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10009549"><a href="/gui2/?type=authors&mode=browse&sel=10009549" target="_blank">Sik A (<span class="authorship-author-name">Sík Attila</span> <span class="authorAux-mtmt"> Idegtudomány</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Itakura M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Takahashi M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hirase H ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;3322273" target="_blank">Hippocampal CA3 and CA2 have distinct bilateral innervation patterns to CA1 in rodents.</a></div> <div> <span class="journal-title">EUROPEAN JOURNAL OF NEUROSCIENCE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0953-816X">0953-816X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1460-9568">1460-9568</a>)</span>: <span class="journal-volume">35</span> <span class="journal-issue">5</span> <span class="page"> pp 702-710 </span> <span class="year">(2012)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1111/j.1460-9568.2012.07993.x" target="_blank" href="https://doi.org/10.1111/j.1460-9568.2012.07993.x"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000301119000007" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000301119000007"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84857995750" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84857995750"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="22339771" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=22339771&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Neuroscience (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 78</span> | Független: 75 | Függő: 3 | Nem jelölt: 0 | WoS jelölt: 74 | Scopus jelölt:&nbsp;75 | WoS/Scopus jelölt:&nbsp;78 | DOI jelölt:&nbsp;78 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;3322273&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 3322273</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 3322273</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2024.12.06. 18:46 Milánkovics Róbert (PTE ÁOK admin 4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Laboratory for Neuron Glia Circuit, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Hirosawa 2-1, Japan Neuronal Networks Group, College of Medical and Dental Sciences, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom Laboratory for Behavioral Genetics, RIKEN Brain Science Institute, Wako, J...</pre> </div></div>