TY - JOUR AU - Christensen, DL AU - Witte, DR AU - Kaduka, L AU - Jorgensen, ME AU - Borch-Johnsen, K AU - Mohan, V AU - Shaw, JE AU - Tabák, Ádám AU - Vistisen, D TI - Moving to an A1C-based diagnosis of diabetes has a different impact on prevalence in different ethnic groups. JF - DIABETES CARE J2 - DIABETES CARE VL - 33 PY - 2010 IS - 3 SP - 580 EP - 582 PG - 3 SN - 0149-5992 DO - 10.2337/dc09-1843 UR - https://m2.mtmt.hu/api/publication/1681007 ID - 1681007 AB - OBJECTIVE To compare screen-detected diabetes prevalence and the degree of diagnostic agreement by ethnicity with the current oral glucose tolerance test (OGTT)-based and newly proposed A1C-based diagnostic criteria. RESEARCH DESIGN AND METHODS Six studies (1999-2009) from Denmark, the U.K., Australia, Greenland, Kenya, and India were tested for the probability of an A1C > or =6.5% among diabetic case subjects based on an OGTT. The difference in probability between centers was analyzed by logistic regression adjusting for relevant confounders. RESULTS Diabetes prevalence was lower with the A1C-based diagnostic criteria in four of six studies. The probability of an A1C > or =6.5% among OGTT-diagnosed case subjects ranged widely (17.0-78.0%) by study center. Differences in diagnostic agreement between ethnic subgroups in the U.K. study were of the same magnitude as between-country comparisons. CONCLUSIONS A shift to an A1C-based diagnosis for diabetes will have substantially different consequences for diabetes prevalence across ethnic groups and populations. LA - English DB - MTMT ER - TY - JOUR AU - Madarasz, E AU - Tamás, Gyula AU - Tabák, Ádám AU - Kerenyi, Z TI - Carbohydrate metabolism and cardiovascular risk factors 4 years after a pregnancy complicated by gestational diabetes. JF - DIABETES RESEARCH AND CLINICAL PRACTICE J2 - DIABETES RES CLIN PR VL - 85 PY - 2009 IS - 2 SP - 197 EP - 202 PG - 6 SN - 0168-8227 DO - 10.1016/j.diabres.2009.05.001 UR - https://m2.mtmt.hu/api/publication/1681015 ID - 1681015 AB - AIMS: The aim of the present study was to determine the prevalence of abnormal glucose tolerance and the metabolic syndrome in a cohort of previously gestational diabetic (GDM) women 4 years after delivery. METHODS: Sixty-eight prior GDM and a control group of 39 women with normal glucose tolerance during pregnancy were invited to participate in a follow-up study. RESULTS: The prevalence of diabetes, impaired glucose tolerance and impaired fasting glucose (IFG) was 21%, 16%, and 6% among prior GDM women and 0%, 15%, and 0% among controls respectively (P=0.0039). Independently of the metabolic syndrome criteria used this status was found more frequently among women with prior GDM (all P<0.05). The prevalence of the metabolic syndrome showed a dose-response relationship with the level of weight categories (P<0.005) as well as with the level of glucose intolerance (P=0.024). CONCLUSION: According to our results a disturbed carbohydrate metabolism and a clustering of cardiovascular risk factors might be observed in previous GDM women 4 years after delivery. LA - English DB - MTMT ER - TY - JOUR AU - Kerenyi, Z AU - Stella, P AU - Nadasdi, A AU - Tabák, Ádám AU - Tamás, Gyula TI - Association between cardiovascular autonomic neuropathy and multimetabolic syndrome in a special cohort of women with prior gestational diabetes mellitus JF - DIABETIC MEDICINE J2 - DIABETIC MED VL - 16 PY - 1999 IS - 9 SP - 794 EP - 795 PG - 2 SN - 0742-3071 UR - https://m2.mtmt.hu/api/publication/1681036 ID - 1681036 LA - English DB - MTMT ER -