@article{MTMT:1013516, title = {Synthesis and transformation of novel cyclic beta-amino acid derivatives from (+)-3-carene}, url = {https://m2.mtmt.hu/api/publication/1013516}, author = {Gyónfalvi, Szilvia and Szakonyi, Zsolt and Fülöp, Ferenc}, doi = {10.1016/j.tetasy.2003.10.001}, journal-iso = {TETRAHEDRON ASYMMETR}, journal = {TETRAHEDRON-ASYMMETRY}, volume = {14}, unique-id = {1013516}, issn = {0957-4166}, abstract = {The regio- and stereoselective addition of chlorosulfonyl isocyanate to (+)-3-carene 1 resulted in beta-lactam 2, which was converted to N-Boc-beta-amino acid 4, beta-amino ester 7, and carboxamide derivatives 18 and 20 via N-Boc activation and mild ring opening. The corresponding beta-amino ester 7 was transformed to 2-thioxopyrimidin-4-one 11 and 2,4-pyrimidinedione 13. LAH reduction of 5 and 7 resulted in amino alcohols 6 and 8. The reaction of 8 with phenyl isothiocyanate, followed by cyclisation, furnished 1,3-oxazine 15. (C) 2003 Elsevier Ltd. All rights reserved.}, year = {2003}, eissn = {1362-511X}, pages = {3965-3972}, orcid-numbers = {Szakonyi, Zsolt/0000-0003-2432-8409; Fülöp, Ferenc/0000-0003-1066-5287} } @article{MTMT:1014481, title = {Synthesis and transformations of enantiomeric 1,2-disubstituted monoterpene derivatives}, url = {https://m2.mtmt.hu/api/publication/1014481}, author = {Szakonyi, Zsolt and Martinek, Tamás and Hetényi, Anasztázia and Fülöp, Ferenc}, doi = {10.1016/S0957-4166(00)00435-3}, journal-iso = {TETRAHEDRON ASYMMETR}, journal = {TETRAHEDRON-ASYMMETRY}, volume = {11}, unique-id = {1014481}, issn = {0957-4166}, abstract = {Regio- and stereospecific addition of chlorosulfonyl isocyanate to (+)- and (-)-alpha -pinene I resulted in enantiomerically pure beta -lactams 2, which were converted to enantiomeric beta -amino esters 3 and 1,3-amino alcohols 4 and 6 with ee >99%. The resulting 1,3-difunctional compounds 3, 4 and 6 were transformed to fused saturated 1,3-heterocycles such as tetrahydro-1,3- oxazines 7 and 9, 2,4-pyrimidinedione 11 and 2-thioxopyrimidin- 4-one 13 enantiomers. (C) 2000 Elsevier Science Ltd. All rights reserved.}, year = {2000}, eissn = {1362-511X}, pages = {4571-4579}, orcid-numbers = {Szakonyi, Zsolt/0000-0003-2432-8409; Martinek, Tamás/0000-0003-3168-8066; Hetényi, Anasztázia/0000-0001-8080-6992; Fülöp, Ferenc/0000-0003-1066-5287} }