TY  - JOUR
AU  - Csende, F
AU  - Hetényi, Anasztázia
AU  - Stájer, Géza
AU  - Fülöp, Ferenc
TI  - Synthesis and structure of cycloalkane- and norbornane-condensed 6-aryl-1,2,4,5-tetrahydropyridazinones
JF  - JOURNAL OF HETEROCYCLIC CHEMISTRY
J2  - J HETEROCYCLIC CHEM
VL  - 41
PY  - 2004
IS  - 2
SP  - 259
EP  - 261
PG  - 3
SN  - 0022-152X
DO  - 10.1002/jhet.5570410217
UR  - https://m2.mtmt.hu/api/publication/1013242
ID  - 1013242
AB  - The Cdouble bondN double bond of certain cis- or trans-cycloalkane and
diexo- or diendo-norbornane-condensed pyridazinones was reduced with
NaBH3CN. The cis- or trans nature of the starting cycloalkane
derivatives was always retained in the saturated products, with a high
degree of diastereoselectivity: the hydrogen on the new stereocenter
and the annelational hydrogen next to the carbonyl always exhibited the
same steric orientation. The stereostructures were determined by means
of nmr measurements and confirmed by molecular modelling.
LA  - English
DB  - MTMT
ER  -