TY - JOUR AU - Horváth, Róbert AU - Fricsovszky, G AU - Papp, E TI - Application of the optical waveguide lightmode spectroscopy to monitor lipid bilayer phase transition JF - BIOSENSORS & BIOELECTRONICS J2 - BIOSENS BIOELECTRON VL - 18 PY - 2003 IS - 4 SP - 415 EP - 428 PG - 14 SN - 0956-5663 DO - 10.1016/S0956-5663(02)00154-9 UR - https://m2.mtmt.hu/api/publication/1412966 ID - 1412966 AB - An instrument for optical waveguide lightmode spectroscopy (OWLS) was designed and developed for measurements at different and controlled temperatures in a range of 15 degreesC around room temperature. The instrument allows to scan the waveguide modes at different wavelengths on the same optical chip using different lasers. This instrument was used to monitor DMPC lipid bilayer main phase transition around the critical temperature. The main problem in these experiments is that the OWLS measurements do not give enough information about an optically anisotropic system like a lipid bilayer. Experimental OWLS data at two different wavelengths can however approximately solve the problem. The temperature dependence of the thickness and the refractive indices (ordinary and extraordinary) for the lipid bilayer around the phase transition is presented. (A theoretical derivation of the extraordinary refractive index is given in Appendix A.) (C) 2002 Elsevier Science B.V. All rights reserved. LA - English DB - MTMT ER - TY - JOUR AU - Horváth, Róbert AU - Pedersen, HC AU - Skivesen, N AU - Selmeczi, D AU - Larsen, NB TI - Optical waveguide sensor for on-line monitoring of bacteria JF - OPTICS LETTERS J2 - OPT LETT VL - 28 PY - 2003 IS - 14 SP - 1233 EP - 1235 PG - 3 SN - 0146-9592 DO - 10.1364/OL.28.001233 UR - https://m2.mtmt.hu/api/publication/1412964 ID - 1412964 AB - A grating-coupled planar optical waveguide sensor is presented for sensing of bacteria by evanescent waves. The waveguide design results in increased depth of penetration into the sample volume, which makes it suitable for detecting micrometer-sized biological objects. We tested the sensor's performance by monitoring the adhesion of Escherichia coli K12 cells to the sensor surface. (C) 2003 Optical Society of America. LA - English DB - MTMT ER - TY - JOUR AU - Voros, J AU - Ramsden, JJ AU - Csúcs, Gábor AU - Szendro, I AU - De Paul, SM AU - Textor, M AU - Spencer, ND TI - Optical grating coupler biosensors JF - BIOMATERIALS J2 - BIOMATERIALS VL - 23 PY - 2002 IS - 17 SP - 3699 EP - 3710 PG - 12 SN - 0142-9612 DO - 10.1016/S0142-9612(02)00103-5 UR - https://m2.mtmt.hu/api/publication/1498591 ID - 1498591 N1 - WoS:hiba:000176522600019 2019-03-03 22:14 cikkazonosító nem egyezik AB - By incorporating a grating in a planar optical waveguide one creates a device with which the spectrum of guided lightmodes can be measured. When the surface of the waveguide is exposed to different solutions, the peaks in the spectrum shift due to molecular interactions with the surface. Optical waveguide lightmode spectroscopy (OWLS) is a highly sensitive technique that is capable of real-time monitoring of these interactions. Since this integrated optical method is based on the measurement of the polarizability density (i.e., refractive index) in the vicinity of the waveguide surface, radioactive, fluorescent or other kinds of labeling are not required. In addition, measurement of at least two guided modes enables the absolute mass of adsorbed Molecules to be determined. In this article, the technique will be described in some detail, and applications from different areas will be discussed. Selected examples will be presented to demonstrate how monitoring the modification of different metal oxides with polymers and the response of the coated oxides to biofluids help in the design of novel biomaterials: how OWLS is useful for accurate bioaffinity sensing. which is a key issue in the development of new drugs; and how the quantitative study of protein-DNA/RNA and cell-surface interactions can enhance the understanding of processes in molecular and cellular biology. (C) 2002 Elsevier Science Ltd. All rights reserved. LA - English DB - MTMT ER - TY - JOUR AU - Picart, C AU - Ladam, G AU - Senger, B AU - Voegel, JC AU - Schaaf, P AU - Cuisinier, FJG AU - Gergely, Csilla TI - Determination of structural parameters characterizing thin films by optical methods: A comparison between scanning angle reflectometry and optical waveguide lightmode spectroscopy JF - JOURNAL OF CHEMICAL PHYSICS J2 - J CHEM PHYS VL - 115 PY - 2001 SP - 1086 EP - 1094 PG - 9 SN - 0021-9606 DO - 10.1063/1.1375156 UR - https://m2.mtmt.hu/api/publication/1912095 ID - 1912095 LA - English DB - MTMT ER -