@article{MTMT:1412956, title = {Guided wave sensing of polyelectrolyte multilayers}, url = {https://m2.mtmt.hu/api/publication/1412956}, author = {Horváth, Róbert and Pedersen, HC and Cuisinier, FJG}, doi = {10.1063/1.2184756}, journal-iso = {APPL PHYS LETT}, journal = {APPLIED PHYSICS LETTERS}, volume = {88}, unique-id = {1412956}, issn = {0003-6951}, abstract = {A planar optical waveguide configuration is proposed to monitor the buildup of thick polyelectrolyte multilayers on the surface of the waveguide in aqueous solutions. Instead of detecting the layer by the electromagnetic evanescent field the polyelectrolyte layer acts as an additional waveguiding film that is sensed by guided waves instead of evanescent waves. This leads to a considerably improved sensitivity and dynamic range.}, keywords = {FILMS; SENSOR; ADSORPTION; FABRICATION; WAVEGUIDES; EXPONENTIAL-GROWTH; biosensors}, year = {2006}, eissn = {1077-3118}, orcid-numbers = {Horváth, Róbert/0000-0001-8617-2302} } @article{MTMT:1913518, title = {Measurement of film thickness up to several hundreds of nanometers using optical waveguide lightmode spectroscopy}, url = {https://m2.mtmt.hu/api/publication/1913518}, author = {Picart, C and Gergely, Csilla and Arntz, Y and Voegel, JC and Schaaf, P and Cuisinier, Fjg and Senger, B}, doi = {10.1016/j.bios.2004.03.005}, journal-iso = {BIOSENS BIOELECTRON}, journal = {BIOSENSORS & BIOELECTRONICS}, volume = {20}, unique-id = {1913518}, issn = {0956-5663}, year = {2004}, eissn = {1873-4235}, pages = {553-561} } @article{MTMT:1412966, title = {Application of the optical waveguide lightmode spectroscopy to monitor lipid bilayer phase transition}, url = {https://m2.mtmt.hu/api/publication/1412966}, author = {Horváth, Róbert and Fricsovszky, G and Papp, E}, doi = {10.1016/S0956-5663(02)00154-9}, journal-iso = {BIOSENS BIOELECTRON}, journal = {BIOSENSORS & BIOELECTRONICS}, volume = {18}, unique-id = {1412966}, issn = {0956-5663}, abstract = {An instrument for optical waveguide lightmode spectroscopy (OWLS) was designed and developed for measurements at different and controlled temperatures in a range of 15 degreesC around room temperature. The instrument allows to scan the waveguide modes at different wavelengths on the same optical chip using different lasers. This instrument was used to monitor DMPC lipid bilayer main phase transition around the critical temperature. The main problem in these experiments is that the OWLS measurements do not give enough information about an optically anisotropic system like a lipid bilayer. Experimental OWLS data at two different wavelengths can however approximately solve the problem. The temperature dependence of the thickness and the refractive indices (ordinary and extraordinary) for the lipid bilayer around the phase transition is presented. (A theoretical derivation of the extraordinary refractive index is given in Appendix A.) (C) 2002 Elsevier Science B.V. All rights reserved.}, keywords = {MEMBRANES; SENSITIVITY; SURFACE; sensors; lipid bilayer; Anisotropy; MOLECULAR-ORIENTATION; phase transition; DMPC; optical waveguide lightmode spectroscopy}, year = {2003}, eissn = {1873-4235}, pages = {415-428}, orcid-numbers = {Horváth, Róbert/0000-0001-8617-2302} } @article{MTMT:1498591, title = {Optical grating coupler biosensors}, url = {https://m2.mtmt.hu/api/publication/1498591}, author = {Voros, J and Ramsden, JJ and Csúcs, Gábor and Szendro, I and De Paul, SM and Textor, M and Spencer, ND}, doi = {10.1016/S0142-9612(02)00103-5}, journal-iso = {BIOMATERIALS}, journal = {BIOMATERIALS}, volume = {23}, unique-id = {1498591}, issn = {0142-9612}, abstract = {By incorporating a grating in a planar optical waveguide one creates a device with which the spectrum of guided lightmodes can be measured. When the surface of the waveguide is exposed to different solutions, the peaks in the spectrum shift due to molecular interactions with the surface. Optical waveguide lightmode spectroscopy (OWLS) is a highly sensitive technique that is capable of real-time monitoring of these interactions. Since this integrated optical method is based on the measurement of the polarizability density (i.e., refractive index) in the vicinity of the waveguide surface, radioactive, fluorescent or other kinds of labeling are not required. In addition, measurement of at least two guided modes enables the absolute mass of adsorbed Molecules to be determined. In this article, the technique will be described in some detail, and applications from different areas will be discussed. Selected examples will be presented to demonstrate how monitoring the modification of different metal oxides with polymers and the response of the coated oxides to biofluids help in the design of novel biomaterials: how OWLS is useful for accurate bioaffinity sensing. which is a key issue in the development of new drugs; and how the quantitative study of protein-DNA/RNA and cell-surface interactions can enhance the understanding of processes in molecular and cellular biology. (C) 2002 Elsevier Science Ltd. All rights reserved.}, year = {2002}, eissn = {1878-5905}, pages = {3699-3710} } @article{MTMT:154415, title = {The effect of UV irradiation on uracil thin layer measured by optical waveguide lightmode spectroscopy}, url = {https://m2.mtmt.hu/api/publication/154415}, author = {Horváth, Róbert and Kerékgyártó, Tibor and Csúcs, Gábor and Gáspár, Sándor and Illyés, P and Rontó, Györgyi and Pap, E}, doi = {10.1016/S0956-5663(00)00123-8}, journal-iso = {BIOSENS BIOELECTRON}, journal = {BIOSENSORS & BIOELECTRONICS}, volume = {16}, unique-id = {154415}, issn = {0956-5663}, keywords = {SENSITIVITY; RADIATION; URACIL; BIOLOGICAL DOSIMETERS; OWLS; optical parameters; biological UV dosimetry; UV radiation}, year = {2001}, eissn = {1873-4235}, pages = {17-21}, orcid-numbers = {Horváth, Róbert/0000-0001-8617-2302} }