TY - JOUR AU - Halász, Péter TI - K-complex, a reactive EEG graphoelement of NREM sleep: an old chap in a new garment. JF - SLEEP MEDICINE REVIEWS J2 - SLEEP MED REV VL - 9 PY - 2005 IS - 5 SP - 391 EP - 412 PG - 22 SN - 1087-0792 DO - 10.1016/j.smrv.2005.04.003 UR - https://m2.mtmt.hu/api/publication/2318569 ID - 2318569 AB - This review summarises data gathered on the KC phenomenon over the past 70 yr. The following issues are discussed: definitions, morphology and topography of KC, the regular participation in NREM sleep, elicitability features of evoked KC, autonomic and motor concomitants, relationship of KC with information processing during NREM sleep, relationship of KC and deltas of NREM sleep, and relationship of KC with sleep cyclicity. KC is a complex multifunctional phenomenon of the sleeping brain involved in information processing and defence against the arousal effect of sensory stimuli. To put the old chap in a new garment, the relationship of KC with synchronisation-type and desynchronisation-type micro-arousals, and the 'cyclic alternating pattern', will be discussed, with an emphasis on the sleep-protecting role of KC and synchronisation-type answers in sleep regulation executed by phasic events. Lastly, the role of KC providing gating functions in idiopathic generalized epilepsies and other, different, sleep disorders are characterised. A 'theoretical epilogue' is appended to show some system theoretical and regulational aspects. LA - English DB - MTMT ER - TY - JOUR AU - Ulbert, István AU - Halgren, E AU - Heit, G AU - Karmos, György TI - Multiple microelectrode-recording system for human intracortical applications. JF - JOURNAL OF NEUROSCIENCE METHODS J2 - J NEUROSCI METH VL - 106 PY - 2001 IS - 1 SP - 69 EP - 79 PG - 11 SN - 0165-0270 DO - 10.1016/S0165-0270(01)00330-2 UR - https://m2.mtmt.hu/api/publication/1121140 ID - 1121140 AB - The human brain is dominated by the neocortex, a large folded surface, whose cellular and synaptic elements are arranged in layers. Since cortical structure is relatively constant across its surface, local information processing can be inferred from multiple laminar recordings of its electrical activity along a line perpendicular to its surface. Such recordings need to be spaced at least as close together as the cortical layers, and need to be wideband in order to sample both low frequency synaptic currents as well as high-frequency action potentials. Finally, any device used in the human brain must comply with strict safety standards. The current paper presents details of a system meeting these criteria, together with sample results obtained from epileptic subjects undergoing acute or chronic intracranial monitoring for definition of the epileptogenic region. LA - English DB - MTMT ER -