@article{MTMT:34729015,
	title = {Új minimálinvazív kezelési lehetőségek jó- és rosszindulatú fül-orr-gégészeti betegségekben nanoszerkezetű hatóanyag-leadó rendszerek alkalmazásával = New minimally invasive treatment options in benign and malignant otorhinolaryngological diseases using nanostructured drug delivery systems},
	url = {https://m2.mtmt.hu/api/publication/34729015},
	author = {Szabó, Diána and Janovák, László and Abdelghafour, Mohamed M. and Takács, Tamás and Csanády, Miklós ifj. and Spengler, Gabriella and Szakács, László and Csanády, Miklós and Rovó, László},
	doi = {10.1556/650.2024.32978},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {165},
	unique-id = {34729015},
	issn = {0030-6002},
	year = {2024},
	eissn = {1788-6120},
	pages = {370-378},
	orcid-numbers = {Janovák, László/0000-0002-2066-319X; Abdelghafour, Mohamed M./0000-0002-7895-4555; Spengler, Gabriella/0000-0001-8085-0950; Rovó, László/0000-0003-1782-1756}
}

@article{MTMT:34154074,
	title = {Mitomycin loaded self-assembled colloidal prodrug nanoparticles for magnetic drug targeting},
	url = {https://m2.mtmt.hu/api/publication/34154074},
	author = {Amin, Keristina and Abdelghafour, Mohamed M. and Varga, Viktória and Kiss, Tamás and Szabó, Diána and Rovó, László and Janovák, László},
	doi = {10.1016/j.jddst.2023.104948},
	journal-iso = {J DRUG DELIV SCI TEC},
	journal = {JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY},
	volume = {88},
	unique-id = {34154074},
	issn = {1773-2247},
	year = {2023},
	eissn = {2588-8943},
	orcid-numbers = {Abdelghafour, Mohamed M./0000-0002-7895-4555; Varga, Viktória/0000-0001-9933-7604; Rovó, László/0000-0003-1782-1756; Janovák, László/0000-0002-2066-319X}
}

@article{MTMT:33293402,
	title = {Self-Assembling Injectable Hydrogel for Controlled Drug Delivery of Antimuscular Atrophy Drug Tilorone},
	url = {https://m2.mtmt.hu/api/publication/33293402},
	author = {Abdelghafour, Mohamed M. and Imre-Deák, Ágota and Kiss, Tamás and Budai-Szűcs, Mária and Katona, Gábor and Ambrus, Rita and Lőrinczi, Bálint and Keller-Pintér, Anikó and Szatmári, István and Szabó, Diána and Rovó, László and Janovák, László},
	doi = {10.3390/pharmaceutics14122723},
	journal-iso = {PHARMACEUTICS},
	journal = {PHARMACEUTICS},
	volume = {14},
	unique-id = {33293402},
	issn = {1999-4923},
	abstract = {A two-component injectable hydrogel was suitably prepared for the encapsulation and prolonged release of tilorone which is an antimuscular atrophy drug. The rapid (7–45 s, depending on the polymer concentration) in situ solidifications of the hydrogel were evoked by the evolving Schiff-base bonds between the aldehyde groups of modified PVA (4-formyl benzoate PVA, PVA-CHO, 5.9 mol% functionalization degree) and the amino groups of 3-mercaptopropionate chitosan (CHIT-SH). The successful modification of the initial polymers was confirmed by both FTIR and NMR measurements; moreover, a new peak appeared in the FTIR spectrum of the 10% w/v PVA-CHO/CHIT-SH hydrogel at 1647 cm−1, indicating the formation of a Schiff base (–CH=N–) and confirming the interaction between the NH2 groups of CHIT–SH and the CHO groups of PVA-CHO for the formation of the dynamic hydrogel. The reaction between the NH2 and CHO groups of the modified biopolymers resulted in a significant increase in the hydrogel’s viscosity which was more than one thousand times greater (9800 mPa·s) than that of the used polymer solutions, which have a viscosity of only 4.6 and 5.8 mPa·s, respectively. Furthermore, the initial chitosan was modified with mercaptopropionic acid (thiol content = 201.85 ± 12 µmol/g) to increase the mucoadhesive properties of the hydrogel. The thiolated chitosan showed a significant increase (~600 mN/mm) in adhesion to the pig intestinal membrane compared to the initial one (~300 mN/mm). The in vitro release of tilorone from the hydrogel was controlled with the crosslinking density/concentration of the hydrogel; the 10% w/v PVA-CHO/CHIT-SH hydrogel had the slowest releasing (21.7 h−1/2) rate, while the 2% w/v PVA-CHO/CHIT-SH hydrogel had the fastest releasing rate (34.6 h−1/2). Due to the characteristics of these hydrogels, their future uses include tissue regeneration scaffolds, wound dressings for skin injuries, and injectable or in situ forming drug delivery systems. Eventually, we hope that the developed hydrogel will be useful in the local treatment of muscle atrophy, such as laryngotracheal atrophy.},
	year = {2022},
	eissn = {1999-4923},
	orcid-numbers = {Abdelghafour, Mohamed M./0000-0002-7895-4555; Imre-Deák, Ágota/0000-0002-6781-1727; Kiss, Tamás/0000-0003-0011-0501; Budai-Szűcs, Mária/0000-0001-5187-5702; Katona, Gábor/0000-0003-1564-4813; Ambrus, Rita/0000-0001-5496-1710; Lőrinczi, Bálint/0000-0001-7773-0034; Keller-Pintér, Anikó/0000-0002-4105-8458; Szatmári, István/0000-0002-8571-5229; Rovó, László/0000-0003-1782-1756; Janovák, László/0000-0002-2066-319X}
}

@article{MTMT:32893726,
	title = {Use of Self-Assembled Colloidal Prodrug Nanoparticles for Controlled Drug Delivery of Anticancer, Antifibrotic and Antibacterial Mitomycin},
	url = {https://m2.mtmt.hu/api/publication/32893726},
	author = {Abdelghafour, Mohamed M. and Imre-Deák, Ágota and Szabó, Diána and Dékány, Imre and Rovó, László and Janovák, László},
	doi = {10.3390/ijms23126807},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {23},
	unique-id = {32893726},
	issn = {1661-6596},
	year = {2022},
	eissn = {1422-0067},
	orcid-numbers = {Abdelghafour, Mohamed M./0000-0002-7895-4555; Imre-Deák, Ágota/0000-0002-6781-1727; Dékány, Imre/0000-0001-5472-5355; Rovó, László/0000-0003-1782-1756; Janovák, László/0000-0002-2066-319X}
}

@article{MTMT:33003489,
	title = {Functionalized Mesoporous Silica Nanoparticles for Drug-Delivery to Multidrug-Resistant Cancer Cells},
	url = {https://m2.mtmt.hu/api/publication/33003489},
	author = {Igaz, Nóra and Bélteky, Péter and Kovács, Dávid and Papp, Csaba Gergő and Rónavári, Andrea and Szabó, Diána and Gácser, Attila and Kónya, Zoltán and Csontné Kiricsi, Mónika},
	doi = {10.2147/IJN.S363952},
	journal-iso = {INT J NANOMED},
	journal = {INTERNATIONAL JOURNAL OF NANOMEDICINE},
	volume = {17},
	unique-id = {33003489},
	issn = {1176-9114},
	abstract = {Background: Multidrug resistance is a common reason behind the failure of chemotherapy. Even if the therapy is effective, serious adverse effects might develop due to the low specificity and selectivity of antineoplastic agents. Mesoporous silica nanoparticles (MSNs) are promising materials for tumor-targeting and drug-delivery due to their small size, relatively inert nature, and extremely large specific surfaces that can be functionalized by therapeutic and targeting entities. We aimed to create a fluorescently labeled MSN-based drug-delivery system and investigate their internalization and drug-releasing capability in drug-sensitive MCF-7 and P-glycoprotein-overexpressing multidrug-resistant MCF-7 KCR cancer cells.Methods and Results: To track the uptake and subcellular distribution of MSNs, particles with covalently coupled red fluorescent Rhodamine B (RhoB) were produced (RhoB@MSNs). Both MCF-7 and MCF-7 KCR cells accumulated a significant amount of RhoB@MSNs. The intracellular RhoB@MSN concentrations did not differ between sensitive and multidrug-resistant cells and were kept at the same level even after cessation of RhoB@MSN exposure. Although most RhoB@MSNs resided in the cytoplasm, significantly more RhoB@MSNs co-localized with lysosomes in multidrug-resistant cells compared to sensitive counterparts. To examine the drug-delivery capability of these particles, RhoB@Rho123@MSNs were established, where RhoB-functionalized nanoparticles carried green fluorescent Rhodamine 123 (Rho123) -a P-glycoprotein substrate - as cargo within mesopores. Significantly higher Rho123 fluorescence intensity was detected in RhoB@Rho123@MSN-treated multidrug-resistant cells than in free Rho123-exposed counterparts. The exceptional drug-delivery potential of MSNs was further verified using Mitomycin C (MMC)-loaded RhoB@MSNs (RhoB@MMC@MSNs). Exposures to RhoB@MMC@MSNs significantly decreased the viability not only of drug-sensitive but of multidrug-resistant cells and the elimination of MDR cells was significantly more robust than upon free MMC treatments.Conclusion: The efficient delivery of Rho123 and MMC to multidrug-resistant cells via MSNs, the amplified and presumably prolonged intracellular drug concentration, and the consequently enhanced cytotoxic effects envision the enormous potential of MSNs to defeat multidrug-resistant cancer.},
	year = {2022},
	eissn = {1178-2013},
	pages = {3079-3096},
	orcid-numbers = {Igaz, Nóra/0000-0003-1580-4397; Papp, Csaba Gergő/0000-0003-4450-0667; Rónavári, Andrea/0000-0001-7054-0975; Kónya, Zoltán/0000-0002-9406-8596; Csontné Kiricsi, Mónika/0000-0002-8416-2052}
}

@article{MTMT:31794441,
	title = {Reversal of multidrug resistance and antitumor promoting activity of 3-oxo-6β-hydroxy- β-amyrin isolated from Pistacia integerrima},
	url = {https://m2.mtmt.hu/api/publication/31794441},
	author = {ABDUR, RAUF and SAUD, BAWAZEER and MUSLIM, RAZA and EMAN, EL-SHARKAWY and MD., HABIBUR RAHMAN and MOHAMED, A. EL-ESAWI and GHIAS, UDDIN and BINA, S. SIDDIQUI and ANEES, AHMED KHALIL and Molnár, József and Csonka, Ákos and Szabó, Diána and HAROON, KHAN and MOHAMMAD, S. MUBARAK and TAIBI, BEN HADDA and MUDYAWATI, KAMARUDDIN and SEEMA, PATEL},
	doi = {10.32604/biocell.2021.013277},
	journal-iso = {BIOCELL},
	journal = {BIOCELL},
	volume = {45},
	unique-id = {31794441},
	issn = {0327-9545},
	year = {2021},
	eissn = {1667-5746},
	pages = {139-147}
}

@article{MTMT:32470529,
	title = {Isolation of Bioactive Compounds from Pistacia integerrima with Promising Effects on Reverse Cancer Multidrug Resistance},
	url = {https://m2.mtmt.hu/api/publication/32470529},
	author = {Bawazeer, Sami and Rauf, Abdur and Mabkhot, Yahia N. and Al-Showiman, Salim S. and Patel, Seema and Gul, Somia and Raza, Muslim and Molnár, József and Szabó, Diána and Csonka, Ákos and Mujeeb-ur-, Rehman and Mubarak, Mohammad S. and Zengin, Gokhan and Ramadan, Mohamed Fawzy},
	doi = {10.1134/S1068162021050204},
	journal-iso = {RUSS J BIOORG CHEM+},
	journal = {RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY},
	volume = {47},
	unique-id = {32470529},
	issn = {1068-1620},
	year = {2021},
	eissn = {1608-330X},
	pages = {997-1003}
}

@{MTMT:32658681,
	title = {SELF-ASSEMBLED MUCOADHESIVE BIOPOLYMER PARTICLE RELEASE SYSTEM AND PREPARATION METHOD THEREOF},
	url = {https://m2.mtmt.hu/api/publication/32658681},
	author = {Janovák, László and Rovó, László and Szabó, Diána and Dékány, Imre and Abdelghafour, Mohamed M.},
	unique-id = {32658681},
	year = {2021},
	orcid-numbers = {Janovák, László/0000-0002-2066-319X; Rovó, László/0000-0003-1782-1756; Abdelghafour, Mohamed M./0000-0002-7895-4555}
}

@article{MTMT:31604537,
	title = {Surface wetting driven release of antifibrotic Mitomycin-C drug from modified biopolymer thin films},
	url = {https://m2.mtmt.hu/api/publication/31604537},
	author = {Takács, Tamás and Abdelghafour, Mohamed M. and Imre-Deák, Ágota and Szabó, Diána and Sebők, Dániel and Dékány, Imre and Rovó, László and Kukovecz, Ákos and Janovák, László},
	doi = {10.1016/j.eurpolymj.2020.109995},
	journal-iso = {EUR POLYM J},
	journal = {EUROPEAN POLYMER JOURNAL},
	volume = {139},
	unique-id = {31604537},
	issn = {0014-3057},
	year = {2020},
	eissn = {1873-1945},
	orcid-numbers = {Abdelghafour, Mohamed M./0000-0002-7895-4555; Imre-Deák, Ágota/0000-0002-6781-1727; Szabó, Diána/0000-0003-4482-0740; Sebők, Dániel/0000-0001-9769-5598; Dékány, Imre/0000-0001-5472-5355; Rovó, László/0000-0003-1782-1756; Kukovecz, Ákos/0000-0003-0716-9557; Janovák, László/0000-0002-2066-319X}
}

@article{MTMT:30758940,
	title = {Hemipharyngo-Laryngectomy for Treatment of T1-2 Hypopharyngeal Tumours},
	url = {https://m2.mtmt.hu/api/publication/30758940},
	author = {Szabó, Diána and Csanády, Miklós and Rovó, László},
	journal-iso = {Am J Otolaryngol Head Neck Surg},
	journal = {American Journal of Otolaryngology and Head and Neck Surgery},
	volume = {2},
	unique-id = {30758940},
	year = {2019},
	eissn = {2640-6640},
	orcid-numbers = {Rovó, László/0000-0003-1782-1756}
}

@article{MTMT:30405220,
	title = {Antifibrotic effect of mitomycin-C on human vocal cord fibroblasts},
	url = {https://m2.mtmt.hu/api/publication/30405220},
	author = {Szabó, Diána and Kovács, Dávid and Endrész, Valéria and Igaz, Nóra and Jenovai, Kitti and Spengler, Gabriella and Tiszlavicz, László and Molnár, József and Burián, Katalin and Csontné Kiricsi, Mónika and Rovó, László},
	doi = {10.1002/lary.27657},
	journal-iso = {LARYNGOSCOPE},
	journal = {LARYNGOSCOPE},
	volume = {129},
	unique-id = {30405220},
	issn = {0023-852X},
	year = {2019},
	eissn = {1531-4995},
	pages = {E255-E262},
	orcid-numbers = {Endrész, Valéria/0000-0002-9402-3857; Igaz, Nóra/0000-0003-1580-4397; Spengler, Gabriella/0000-0001-8085-0950; Tiszlavicz, László/0000-0003-1134-6587; Burián, Katalin/0000-0003-1300-2374; Csontné Kiricsi, Mónika/0000-0002-8416-2052; Rovó, László/0000-0003-1782-1756}
}

@article{MTMT:30758937,
	title = {A középarc lágy részeinek nasolabialis függesztése: új, minimálinvazív és reverzibilis módszer az arc statikus szimmetrizálására végleges arcidegbénulásban [Nasolabial suspension of the malar fat pad: a new, minimally invasive and reversible technique for facial symmetrization in permanent facial paralysis]},
	url = {https://m2.mtmt.hu/api/publication/30758937},
	author = {Vass, Gábor and Bere, Zsófia and Szabó, Diána and Rovó, László},
	doi = {10.1556/650.2019.31344},
	journal-iso = {ORV HETIL},
	journal = {ORVOSI HETILAP},
	volume = {160},
	unique-id = {30758937},
	issn = {0030-6002},
	year = {2019},
	eissn = {1788-6120},
	pages = {869-872},
	orcid-numbers = {Vass, Gábor/0000-0003-0787-8679; Bere, Zsófia/0000-0002-8342-1059; Rovó, László/0000-0003-1782-1756}
}

@article{MTMT:3341125,
	title = {In Vitro Studies of Anti-Hemolytic and Cytotoxic Activity of Procyanidin-Rich Extract from the Leaves of Actinidia arguta},
	url = {https://m2.mtmt.hu/api/publication/3341125},
	author = {Cyboran-Mikolajczyk, S and Csonka, Ákos and Molnár, József and Szabó, Diána and Oszmianski, J and Kleszczynska, H},
	doi = {10.1515/pjfns-2017-0021},
	journal-iso = {POLISH J FOOD NUTR SCI},
	journal = {POLISH JOURNAL OF FOOD AND NUTRITION SCIENCES},
	volume = {68},
	unique-id = {3341125},
	issn = {1230-0322},
	year = {2018},
	eissn = {2083-6007},
	pages = {171-177}
}

@article{MTMT:3370144,
	title = {Multidrug resistance reversal activity of extract and a rare dimeric naphthoquinone from Diospyros lotus},
	url = {https://m2.mtmt.hu/api/publication/3370144},
	author = {Rauf, A and Shaheen, U and Raza, M and Uddin, G and Hadda, TB and Mabkhot, YN and Jehan, N and Ahmad, B and Raza, S and Molnár, József and Csonka, Ákos and Szabó, Diána},
	journal-iso = {PAK J PHARM SCI},
	journal = {PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES},
	volume = {31},
	unique-id = {3370144},
	issn = {1011-601X},
	abstract = {A dimeric naphthoquinone namely dihydrodyspyrole R (1) was purified once more from Diospyros lotus. Dihydrodyspyrole R and chloroform fractions were evaluated for their effects on the reversion of multidrug resistance (MDR). The compounds (1) and extract exhibited promising MDR reversing effect in a dose-dependent manner against mouse T-lymphoma cell line. Molecular docking of compound 1 revealed the correlation between in-silico with in-vitro results. The molecular docking results showed that compound 1 is bind closely where co-crystal ligand of P-gp is present. But usually, computational investigation predicts that, if a compound gives lesser score then compound will exhibit good activity. Hence, the docking scores of compound 1 are the near to the Rhodamine. It is conclude that there are certain important structural features of compound 1which are responsible for the inhibiting potency of P-gp from mice. The computational Petra/Osiris/Molinspiration (POM) analysis confirms the possibility of use of compound 1 without side effect or less toxicity risks.},
	year = {2018},
	eissn = {1011-601X},
	pages = {821-825}
}

@article{MTMT:31402136,
	title = {Mitomycin-C fibrosisgátló hatása humán primer hangszalag-fibrolastokon - felső légúti hegesedések kezelésének új lehetősége},
	url = {https://m2.mtmt.hu/api/publication/31402136},
	author = {Szabó, Diána and Kovács, Dávid and Endrész, Valéria and Igaz, Nóra and Spengler, Gabriella and Csontné Kiricsi, Mónika and Tiszlavicz, László and Rovó, László},
	journal-iso = {FÜL-ORR-GÉGEGYÓGYÁSZAT},
	journal = {FÜL-ORR-GÉGEGYÓGYÁSZAT},
	volume = {64},
	unique-id = {31402136},
	issn = {0016-237X},
	year = {2018},
	pages = {110-110},
	orcid-numbers = {Endrész, Valéria/0000-0002-9402-3857; Igaz, Nóra/0000-0003-1580-4397; Spengler, Gabriella/0000-0001-8085-0950; Csontné Kiricsi, Mónika/0000-0002-8416-2052; Tiszlavicz, László/0000-0003-1134-6587; Rovó, László/0000-0003-1782-1756}
}

@article{MTMT:3240653,
	title = {Isolation of Chlorogenic Acid from Soil Borne Fungi Screlotium rolfsii, their Reversal of Multidrug Resistance and anti-proliferative in Mouse Lymphoma cells},
	url = {https://m2.mtmt.hu/api/publication/3240653},
	author = {Bashir, Ahmad and Muhammad, Rizwan and Abdur, Rauf and Muslim, Raza and Shumaila, Bashir and Molnár, József and Csonka, Ákos and Szabó, Diána and Mohammad, S Mubarak and Mah, Noor and Bina, S Siddiqui},
	doi = {10.2174/1573406413666170612110443},
	journal-iso = {MED CHEM},
	journal = {MEDICINAL CHEMISTRY},
	volume = {13},
	unique-id = {3240653},
	issn = {1573-4064},
	abstract = {BACKGROUND: Fungi performing a wide range of function in soil by secreting low molecular weight compound known as secondary metabolites. S. rolfsii is a soil borne phytopathogenic fungi was used for the production of bioactive compounds. OBJECTIVE: The present study belongs to evaluate the anticancer potentials of a secondary metabolites isolated from S. rolfsii, their multidrug resistance (MDR), and molecular docking study. METHOD: (1S,3R,4R,5R,E)-3-(3-(3,4-Dihydroxyphenyl)acryloyloxy)-1,4,5 trihydroxycyclohexanecarboxylic acid (1), or best known as chlorogenic acid, was isolated from the ethyl acetate fraction of crude secondary metabolites produced by the soil borne Fungus Screlotium rolfsii. Structure of chlorogenic acid (1) was confirmed by means of FT-IR, 1H NMR, 13C NMR, and mass spectrometry as well as by melting point. RESULTS: Effect of compound 1 on the reversion of multidrug resistant (MDR) mediated by P-glycoprotein (P-gp) against cancer cells was evaluated with a rhodamine-123 exclusion screening test on human mdr1 gene transfected mouse gene transfected L5178 and L5178Y mouse T-cell lymphoma. Compound 1 was also evaluated for Anti-proliferative effect on the L5178 mouse T-cell lymphoma cell line. CONCLUSION: Results from the present investigation revealed that compound 1 exhibits excellent MDR reversing effect in a dose-dependent manner against mouse T-lymphoma cell line. Compound 1 also showed anti-proliferative effect on L5178Y mouse T-lymphoma cell line.},
	year = {2017},
	eissn = {1875-6638},
	pages = {721-726}
}

@misc{MTMT:3341246,
	title = {4th Congress of European ORL- HNS. Antifibrotic effect of Mitomycin-C human vocal cord fibroblast - impact on upper airway stenosis treatment},
	url = {https://m2.mtmt.hu/api/publication/3341246},
	author = {Szabó, Diána and Endrész, Valéria and Dávid, Kovács and Igaz, Nóra and Spengler, Gabriella and Molnár, József and Burián, Katalin and Csontné Kiricsi, Mónika and Rovó, László},
	unique-id = {3341246},
	year = {2017},
	pages = {110-110},
	orcid-numbers = {Endrész, Valéria/0000-0002-9402-3857; Igaz, Nóra/0000-0003-1580-4397; Spengler, Gabriella/0000-0001-8085-0950; Burián, Katalin/0000-0003-1300-2374; Csontné Kiricsi, Mónika/0000-0002-8416-2052; Rovó, László/0000-0003-1782-1756}
}

@article{MTMT:3241401,
	title = {Intranasalis szteroidterápia alkalmazása gyermekkori felső légúti betegségekben},
	url = {https://m2.mtmt.hu/api/publication/3241401},
	author = {Szabó, Diána and Bella, Zsolt},
	journal-iso = {GYERMEKORVOS TOVÁBBKÉPZÉS},
	journal = {GYERMEKORVOS TOVÁBBKÉPZÉS},
	volume = {16},
	unique-id = {3241401},
	issn = {1589-0309},
	year = {2017},
	pages = {81-83}
}

@article{MTMT:3241061,
	title = {Intranasalis szteroid terápia alkalmazása gyermekkori felső légúti betegségekben},
	url = {https://m2.mtmt.hu/api/publication/3241061},
	author = {Szabó, Diána and Bella, Zsolt},
	journal-iso = {GYERMEKGYÓGYÁSZATI TOVÁBBKÉPZŐ SZEMLE},
	journal = {GYERMEKGYÓGYÁSZATI TOVÁBBKÉPZŐ SZEMLE},
	volume = {22},
	unique-id = {3241061},
	issn = {1585-4396},
	year = {2017},
	pages = {103-104}
}

@article{MTMT:3073568,
	title = {Isolation and Structure Elucidation, Molecular Docking Studies of Screlotiumol from Soil Borne Fungi Screlotium rolfsii and their Reversal of Multidrug Resistance in Mouse Lymphoma Cells},
	url = {https://m2.mtmt.hu/api/publication/3073568},
	author = {Ahmad, B and Rizwan, M and Rauf, A and Raza, M and Azam, S and Bashir, S and Molnár, József and Csonka, Ákos and Szabó, Diána},
	doi = {10.7314/APJCP.2016.17.4.2083},
	journal-iso = {ASIAN PAC J CANCER P},
	journal = {ASIAN PACIFIC JOURNAL OF CANCER PREVENTION},
	volume = {17},
	unique-id = {3073568},
	issn = {1513-7368},
	abstract = {A new compound namely (13-(3,3-dihydroxypropyl)-1,6-dihydroxy-3,4-dihydro-1H-isochromen-8(5H)-one (1) was isolated from an ethyl acetate extract of the borne fungi Screlotium rolfsii. Its chemical structure was elucidated by spectroscopic analysis. Screlotiumol 1 were evaluated for their effects on the reversion of multidrug resistant (MDR) mediated by P-glycoprotein (P-gp) of the soil borne fungi. The multidrug resistant P-glycoprotein is a target for chemotherapeutic drugs in cancer cells. In the present study rhodamine-123 exclusion screening test on human mdr1 gene transfected mouse gene transfected L5178 and L5178Y mouse T-cell lymphoma which showed excellent MDR reversing effect in a dose dependent manner against mouse T-lymphoma cell line. Moreover, molecular docking studies of compound-1 also showed better results as compared with the standard. Therefore the preliminary results obtained from this study suggest that screlotiumol 1 could be used as a potential agent for the treatment of cancer.},
	year = {2016},
	eissn = {2476-762X},
	pages = {2083-2087}
}

@article{MTMT:3073567,
	title = {Reversal of Multidrug Resistance and Computational Studies of Pistagremic Acid Isolated from Pistacia integerrima.},
	url = {https://m2.mtmt.hu/api/publication/3073567},
	author = {Rauf, A and Uddin, G and Raza, M and Ahmad, A and Jehan, N and Ahmad, B and Nisar, M and Molnár, József and Csonka, Ákos and Szabó, Diána and Khan, A and Farooq, U and Noor, M},
	doi = {10.7314/APJCP.2016.17.4.2311},
	journal-iso = {ASIAN PAC J CANCER P},
	journal = {ASIAN PACIFIC JOURNAL OF CANCER PREVENTION},
	volume = {17},
	unique-id = {3073567},
	issn = {1513-7368},
	abstract = {Pistagremic acid (PA) is a bioactive triterpenoid isolated from various parts of Pistacia integerrima plants. The aim of this research was to investigate PA for reversion of multidrug resistant (MDR) mediated by P-glycoprotein using rhodamine-123 exclusion study on a multidrug resistant human ABCB1 (ATP-binding cassette, sub-family B, member 1) gene-transfected mouse T-lymphoma cell line in vitro. Results were similar to those with verapamil as a positive control. Docking studies of PA and standard Rhodamine123 were carried out against a P-gp crystal structure which showed satisfactory results. Actually, PA cannot bind exactly where co-crystallized ligand of P-gp is already present. However, the docking study predicted that if a compound gives a lesser score then it may have some potency. The docking scores of PA and Rhodamine were similar. Therefore, we can conclude that there are certain important chemical features of PA which are responsible for the inhibiting potency of P-gp.},
	year = {2016},
	eissn = {2476-762X},
	pages = {2311-2314}
}

@article{MTMT:3013412,
	title = {Reversal of Multidrug Resistance in Mouse Lymphoma Cells by Extracts and Flavonoids from Pistacia integerrima},
	url = {https://m2.mtmt.hu/api/publication/3013412},
	author = {Rauf, A and Uddin, G and Raza, M and Ahmad, B and Jehan, N and Siddiqui, BS and Molnár, József and Csonka, Ákos and Szabó, Diána},
	doi = {10.7314/APJCP.2016.17.1.51},
	journal-iso = {ASIAN PAC J CANCER P},
	journal = {ASIAN PACIFIC JOURNAL OF CANCER PREVENTION},
	volume = {17},
	unique-id = {3013412},
	issn = {1513-7368},
	abstract = {Phytochemical investigation of Pistacia integerrima has highlighted isolation of two known compounds naringenin (1) and dihydrokaempferol (2). A crude extract and these isolated compounds were here evaluated for their effects on reversion of multidrug resistance (MDR) mediated by P-glycoprotein (P-gp). The multidrug resistance P-glycoprotein is a target for chemotherapeutic drugs from cancer cells. In the present study rhodamine- 123 exclusion screening test on human mdr1 gene transfected mouse gene transfected L5178 and L5178Y mouse T-cell lymphoma cells showed excellent MDR reversing effects in a dose dependent manner. In-silico molecular docking investigations demonstrated a common binding site for Rhodamine123, and compounds naringenin and dihydrokaempferol. Our results showed that the relative docking energies estimated by docking softwares were in satisfactory correlation with the experimental activities. Preliminary interaction profile of P-gp docked complexes were also analysed in order to understand the nature of binding modes of these compounds. Our computational investigation suggested that the compounds interactions with the hydrophobic pocket of P-gp are mainly related to the inhibitory activity. Moreover this study s a platform for the discovery of novel natural compounds from herbal origin, as inhibitor molecules against the P-glycoprotein for the treatment of cancer.},
	year = {2016},
	eissn = {2476-762X},
	pages = {51-55}
}

@article{MTMT:2973115,
	title = {A Rare Class of New Dimeric Naphthoquinones from Diospyros lotus have Multidrug Reversal and Antiproliferative Effects},
	url = {https://m2.mtmt.hu/api/publication/2973115},
	author = {Rauf, A and Uddin, G and Siddiqui, BS and Molnár, József and Csonka, Ákos and Ahmad, B and Szabó, Diána and Farooq, U and Khan, A},
	doi = {10.3389/fphar.2015.00293},
	journal-iso = {FRONT PHARMACOL},
	journal = {FRONTIERS IN PHARMACOLOGY},
	volume = {16},
	unique-id = {2973115},
	year = {2015},
	eissn = {1663-9812}
}

@article{MTMT:2839173,
	title = {A microdebriderrel végzett intracapsularis shaver tonsillectomia és a hagyományos extracapsularis tonsillectomia összehasonlítása a posztoperatív fájdalom és a sebgyógyulás tekintetében},
	url = {https://m2.mtmt.hu/api/publication/2839173},
	author = {Bach, Ádám and Bella, Zsolt and Sztanó, Balázs and Vass, Gábor and Szakács, László and Szabó, Diána and Jóri, József and Rovó, László},
	journal-iso = {FÜL-ORR-GÉGEGYÓGYÁSZAT},
	journal = {FÜL-ORR-GÉGEGYÓGYÁSZAT},
	volume = {60},
	unique-id = {2839173},
	issn = {0016-237X},
	abstract = {A szerzők randomizált, prospektív, kettős vak vizsgálatuk során összehasonlították az intracapsularis shaver tonsillectomiát és a hagyományos extracapsularis tonsillectomiát a posztoperatív fájdalom és a sebgyógyulási zavarok tekintetében. A szakirodalomban is egyedülálló módon, a betegek jobb és bal oldali tonsilláját különböző módszerrel távolították el, ezzel kiküszöbölve az egyénenként igen eltérő fájdalomtolerancia és sebgyógyulási különbségek vizsgálati eredményeket torzító hatásait. A két műtéti technika között szignifikáns különbség sem a posztoperatív fájdalom, sem a sebgyógyulás vizsgált paramétereinek tekintetében nem volt kimutatható.},
	keywords = {TONSILLECTOMIA; MŰTÉT UTÁNI IDŐSZAK; SEBGYÓGYULÁS},
	year = {2014},
	pages = {54-57},
	orcid-numbers = {Bach, Ádám/0000-0001-9265-1043; Sztanó, Balázs/0000-0002-9925-4849; Vass, Gábor/0000-0003-0787-8679; Rovó, László/0000-0003-1782-1756}
}

@article{MTMT:2757043,
	title = {Analysis of the interaction of normal human fibroblasts and different cancer cells in mixed cultures by xcelligence studies},
	url = {https://m2.mtmt.hu/api/publication/2757043},
	author = {Szabó, Diána and Spengler, Gabriella and Molnár, József and Gábor, Tax and Kornélia, Szabó and Rovó, László},
	journal-iso = {ANTICANCER RES},
	journal = {ANTICANCER RESEARCH},
	volume = {34},
	unique-id = {2757043},
	issn = {0250-7005},
	year = {2014},
	eissn = {1791-7530},
	pages = {6197-6197},
	orcid-numbers = {Spengler, Gabriella/0000-0001-8085-0950; Rovó, László/0000-0003-1782-1756}
}

@CONFERENCE{MTMT:2834232,
	title = {A laryngo-trachealis szűkületek nanotechnológiai módszereket felhasználó minimál invazív kezelése},
	url = {https://m2.mtmt.hu/api/publication/2834232},
	author = {Szabó, Diána and Molnár, József and Janovák, László and Dékány, Imre and Rovó, László},
	booktitle = {Magyar Fül-orr-gége és Fej-nyaksebész Orvosok Egyesülete 43.kongresszusa},
	unique-id = {2834232},
	year = {2014},
	orcid-numbers = {Janovák, László/0000-0002-2066-319X; Rovó, László/0000-0003-1782-1756}
}

@CONFERENCE{MTMT:2574614,
	title = {Topical and delayed usage of Mitomycin-C for the treatment of laryngotracheal stenosis},
	url = {https://m2.mtmt.hu/api/publication/2574614},
	author = {Szabó, Diána and Rovó, László and Bere, Zsófia and Molnár, József and Janovák, László and Imre, Dékány},
	booktitle = {2nd Meeting of European Academy of ORL-HNS and CE ORL-HNS otorhinolaryngology & head and neck surgery},
	unique-id = {2574614},
	year = {2013},
	orcid-numbers = {Rovó, László/0000-0003-1782-1756; Bere, Zsófia/0000-0002-8342-1059; Janovák, László/0000-0002-2066-319X}
}

@misc{MTMT:2516319,
	title = {Nanotechnológia lehetőségei az endoscopos gégesebészetben},
	url = {https://m2.mtmt.hu/api/publication/2516319},
	author = {Szabó, Diána and Csanády, Miklós and Molnár, József and Janovák, László and Dékány, Imre and Rovó, László},
	unique-id = {2516319},
	year = {2012},
	orcid-numbers = {Janovák, László/0000-0002-2066-319X; Rovó, László/0000-0003-1782-1756}
}

@CONFERENCE{MTMT:2516295,
	title = {Supracricoide Hemipharyngo-Laryngektomie der T1, T2 Tumoren des Sinus Piriformis},
	url = {https://m2.mtmt.hu/api/publication/2516295},
	author = {Csanády, M and Sztanó, B and Szabó, Diána and Czinger, J and Jóri, J},
	booktitle = {80. Deutscher HNO Kongress},
	unique-id = {2516295},
	year = {2009}
}

@CONFERENCE{MTMT:2574629,
	title = {Supracricoid hemipharyngo-laryngectomy for treatment of T1-2 hypopharyngeal tumors},
	url = {https://m2.mtmt.hu/api/publication/2574629},
	author = {Szabó, Diána and Csanády, M and Sztanó, B and Czigner, J and Jóri, J},
	booktitle = {79. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V},
	unique-id = {2574629},
	year = {2008}
}

@CONFERENCE{MTMT:2516277,
	title = {Juvenilis gégepapilloma},
	url = {https://m2.mtmt.hu/api/publication/2516277},
	author = {Szabó, Diána and Rovó, László and Németh, I and Jóri, J},
	booktitle = {Magyar Gyermek Fül-, Orr-, Gégeorvosok 17. Kongresszusa},
	unique-id = {2516277},
	year = {2007},
	orcid-numbers = {Rovó, László/0000-0003-1782-1756}
}

@CONFERENCE{MTMT:2516262,
	title = {A gastroesophagealis refluxbetegség aktuális fül-orr-gégészeti irodalma},
	url = {https://m2.mtmt.hu/api/publication/2516262},
	author = {Rovó, László and Szabó, Diána},
	booktitle = {A Magyar Fül-, Orr-, Gégeszakorvosok Egyesülete},
	unique-id = {2516262},
	year = {2006},
	orcid-numbers = {Rovó, László/0000-0003-1782-1756}
}

@CONFERENCE{MTMT:2516236,
	title = {Botulinus toxin okozta kétoldali hangszalag bénulás ritka esete},
	url = {https://m2.mtmt.hu/api/publication/2516236},
	author = {Szabó, Diána and Rovó, László},
	booktitle = {A Magyar Fül-, Orr-, Gégeszakorvosok Egyesülete},
	unique-id = {2516236},
	year = {2006},
	pages = {x},
	orcid-numbers = {Rovó, László/0000-0003-1782-1756}
}

@CONFERENCE{MTMT:2516205,
	title = {Agyideg bénulások hátterében álló nasopharyngealis tumor. irodalmi áttekintés egy eset kapcsán},
	url = {https://m2.mtmt.hu/api/publication/2516205},
	author = {Szabó, Diána and Czigner, J},
	booktitle = {A Magyar Onkológusok Társaságának XXVI. Kongesszusa},
	unique-id = {2516205},
	year = {2005},
	pages = {˘"}
}

@CONFERENCE{MTMT:2515719,
	title = {Specifikus COX-2 gátló vegyületek hatása a monocyták migrációjára és adhéziójára},
	url = {https://m2.mtmt.hu/api/publication/2515719},
	author = {Szabó, Diána and Czigner, J and Csanády, M and Gires, O and Lang, S and Kastenbauer, E},
	booktitle = {A Magyar Fül-, Orr-, Gégeszakorvosok Egyesülete},
	unique-id = {2515719},
	year = {2002},
	pages = {"˘"}
}

@article{MTMT:1862584,
	title = {Effects of naturally occurring glucosides, solasodine glucosides, ginsenosides and parishin derivatives on multidrug resistance of lymphoma cells and leukocyte functions.},
	url = {https://m2.mtmt.hu/api/publication/1862584},
	author = {Adalbert, Lívia and Szabó, Diána and Petri, IB and Shoyama, Y and Lin, YH and Molnár, József},
	journal-iso = {IN VIVO},
	journal = {IN VIVO},
	volume = {15},
	unique-id = {1862584},
	issn = {0258-851X},
	abstract = {Solamargine, solasonine, ginsenosides and parishin-related compounds were investigated for their effects on mdr efflux pump of lymphoma cells, and their effects on T cell proliferative assays and cell mediated immune functions, antibody-dependent cellular cytotoxicity (ADCC) and natural killer (NK) cell activity of human peripheral mononuclear cells. Solamargine and solasonine were the only drugs which inhibited all of the tested immune functions; however, ginsenoside Rc and Rd enhanced T cell proliferative assays and marginally increased the NK cell activity. The majority of the compounds were not able to reverse the multidrug resistance of mouse lymphoma cells. However, ginsenosides Rc, Rd and parishin C were able to moderately reduce the activity of the efflux pump. Parishin, parishin C and crude extract significantly enhanced the ADCC reaction.},
	keywords = {Animals; Humans; MICE; Dose-Response Relationship, Drug; Lymphocyte Activation/*drug effects; Drug Resistance, Multiple; *Drug Resistance, Neoplasm; Tumor Cells, Cultured/drug effects; Solanaceous Alkaloids/chemistry/*pharmacology; Saponins/chemistry/*pharmacology; *Lymphoma, T-Cell; Leukocytes, Mononuclear/cytology/drug effects; Killer Cells, Natural/cytology/drug effects; Glucosides/chemistry/*pharmacology; Ginsenosides},
	year = {2001},
	eissn = {1791-7549},
	pages = {151-156}
}

@mastersthesis{MTMT:2514036,
	title = {Reversal of multidrug resistance in tumor cells.},
	url = {https://m2.mtmt.hu/api/publication/2514036},
	author = {Szabó, Diána},
	publisher = {SZTE},
	unique-id = {2514036},
	year = {2001}
}

@article{MTMT:1091894,
	title = {Ellipticine analogues and related compounds as inhibitors of reverse transcriptase and as inhibitors of the efflux pump},
	url = {https://m2.mtmt.hu/api/publication/1091894},
	author = {Sharples, D and Hajós, György and Riedl, Zsuzsanna and Csányi, Dorottya and Molnár, József and Szabó, Diána},
	doi = {10.1002/1521-4184(200109)334:8/9<269::aid-ardp269>3.0.co;2-#},
	journal-iso = {ARCH PHARM},
	journal = {ARCHIV DER PHARMAZIE},
	volume = {334},
	unique-id = {1091894},
	issn = {0365-6233},
	abstract = {Ten polycyclic derivatives related to ellipticine have been synthesised and tested for their intercalating, reverse transcriptase (RT) inhibitory and multidrug resistance efflux pump inhibitory properties. The intercalating activity and the RT inhibitory activity of the derivatives suggest that ellipticine analogues bind at an allosteric binding site on RT or that this inhibition could be controlled at the DNA level. The MDR efflux pump inhibitory activities of these derivatives, however, appears to be unrelated to the DNA binding ability.},
	year = {2001},
	eissn = {1521-4184},
	pages = {269-274}
}

@mastersthesis{MTMT:31255439,
	title = {Reversal of multidrug resistance in tumor cells In Vitro},
	url = {https://m2.mtmt.hu/api/publication/31255439},
	author = {Szabó, Diána},
	publisher = {SZTE},
	unique-id = {31255439},
	year = {2001}
}

@{MTMT:2518758,
	title = {Neue substituierte Disiloxane, Verfahren zu ihrer Herstellung und ihre Verwendung zur Umkehrung der Multidrugresistenz (Mdr)},
	url = {https://m2.mtmt.hu/api/publication/2518758},
	author = {Szabó, Diána and Molnár, József},
	unique-id = {2518758},
	year = {2000}
}

@article{MTMT:1091890,
	title = {Nonnucleoside reverse transcriptase inhibitors},
	url = {https://m2.mtmt.hu/api/publication/1091890},
	author = {Hajós, György and Riedl, Zsuzsanna and Molnár, József and Szabó, Diána},
	doi = {10.1358/dof.2000.025.01.858638},
	journal-iso = {DRUG FUTURE},
	journal = {DRUGS OF THE FUTURE},
	volume = {25},
	unique-id = {1091890},
	issn = {0377-8282},
	year = {2000},
	eissn = {2013-0368},
	pages = {47-62}
}

@article{MTMT:1766763,
	title = {Membrane associated antitumor effects of crocine-, ginsenoside- and cannabinoid derivates},
	url = {https://m2.mtmt.hu/api/publication/1766763},
	author = {Molnár, József and Szabó, Diána and Pusztai, Rozália and Mucsi, I and Adalbert, Lívia and Ocsovszki, Imre and Kawata, E and Shoyama, Y},
	journal-iso = {ANTICANCER RES},
	journal = {ANTICANCER RESEARCH},
	volume = {20},
	unique-id = {1766763},
	issn = {0250-7005},
	keywords = {Animals; Humans; MICE; Cercopithecus aethiops; Tumor Cells, Cultured; structure-activity relationship; Cell Survival/*drug effects; *Plants, Medicinal; Drug Resistance, Multiple; Verapamil/pharmacology; Antineoplastic Agents/*toxicity; Drug Screening Assays, Antitumor; Vero Cells; Lymphoma, T-Cell; Tetrahydrocannabinol/toxicity; Terpenes/toxicity; Saponins/*toxicity; Panax/*toxicity; Glucosides/toxicity; Cyclohexenes; Carotenoids/*toxicity; Cannabinoids/*toxicity},
	year = {2000},
	eissn = {1791-7530},
	pages = {861-867},
	orcid-numbers = {Ocsovszki, Imre/0000-0003-1290-996X}
}

@article{MTMT:1862585,
	title = {Reversal of multidrug resistance of tumor cells.},
	url = {https://m2.mtmt.hu/api/publication/1862585},
	author = {Szabó, Diána and Keyzer, H and Kaiser, HE and Molnár, József},
	journal-iso = {ANTICANCER RES},
	journal = {ANTICANCER RESEARCH},
	volume = {20},
	unique-id = {1862585},
	issn = {0250-7005},
	abstract = {Drug resistance to chemotherapy is rapidly emerging. Resistance to one drug carries over resistance to unrelated anticancer drugs leading to multidrug resistance (MDR). A major factor of MDR is P-glycoprotein (P-gp) mediated ABC transport found in many eukaryotic cells. P-gp acts as a drug eMux pump. The mdr1 gene involved in P-gp 170 protein production is localized in the human chromosome 7 band p2 1.0-21.1. Point mutations after cross-resistance patterns. A variety of stimuli increase the expression of the mdr1 gene: lowered extracellular pH, heat shock, arsenite, cytotoxic agents, anticancer drugs, transfection with oncogenes, HIV-I, and UV-irradiation. An alternative hypothesis to the efflux pump claims that P-gp modifies the intracellular environment to reduce accumulation of anticancer drugs in cancer cells by creating ionic or proton gradients. Chemosensitizers that block P-gp drug extrusion are generally lipid-soluble at physiological pH, possess a basic nitrogen atom and at least two co-planar rings. P-gp blocking does not depend on drug chirality. This opens the way of treating P-gp related MDR with chiral versions of drugs relatively harmless in terms of side-effects. We believe that resistance modifiers combined with cytostatics will chemotherapeutically be more effective for cancer patients.},
	keywords = {Animals; Humans; PHOSPHORYLATION; Gene Expression Regulation, Neoplastic; Molecular Conformation; glycosylation; Antipsychotic Agents/pharmacology; Tumor Cells, Cultured/drug effects; P-Glycoprotein/antagonists & inhibitors/chemistry/*physiology; Genes, MDR/*physiology; Drug Resistance, Neoplasm/genetics/*physiology; Drug Resistance, Multiple/genetics/*physiology; Antineoplastic Agents/chemistry/metabolism; ATP-Binding Cassette Transporters/physiology},
	year = {2000},
	eissn = {1791-7530},
	pages = {4261-4274}
}

@article{MTMT:2398291,
	title = {Models for reversal of resistance},
	url = {https://m2.mtmt.hu/api/publication/2398291},
	author = {Molnár, József and Gunics, Gy and Miskolczi, Cs and Szabó, Diána and Pusztai, Rozália and Kristiansen, J and Varga, A and Keyzer, H},
	journal-iso = {J ANTIMICROB CHEMOTH},
	journal = {JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY},
	volume = {44},
	unique-id = {2398291},
	issn = {0305-7453},
	year = {1999},
	eissn = {1460-2091},
	pages = {15}
}

@article{MTMT:1862586,
	title = {Chemical structure and tumor type specificity of "half-mustard type" phenothiazines.},
	url = {https://m2.mtmt.hu/api/publication/1862586},
	author = {Motohashi, N and Kurihara, T and Sakagami, H and Szabó, Diána and Csuri, K and Molnár, József},
	journal-iso = {ANTICANCER RES},
	journal = {ANTICANCER RESEARCH},
	volume = {19},
	unique-id = {1862586},
	issn = {0250-7005},
	abstract = {The antiproliferative activity of six "half-mustard type" phenothiazines against a total of 54 tumor cell lines: 4 leukemia, 9 non-small-cell lung, 7 colon-, 5 CNS-, 8 melanoma, 6 ovarian-, 8 renal-, 1 prostate and 6 breast cancer was determined by NCI-Information Intensive-Approach. The C-2 position of phenothiazines were substituted with H, Cl and CF3 groups. The half-mustard and ring system was linked either by a propylene or a butylene bridge. Colon-cancer cell showed the highest sensitivity against "half-mustard type" phenothiazines, followed by leukemia, melanoma, prostate-, CNS-, breast-, lung-, renal and ovarian cancer cells. These data suggest the "cancer-type-specific" antitumor action of "half-mustard type" phenothiazines.},
	keywords = {Female; Male; Humans; Organ Specificity; structure-activity relationship; Carcinoma/pathology; molecular structure; Lung Neoplasms/pathology; Drug Screening Assays, Antitumor; Colonic Neoplasms/pathology; Tumor Cells, Cultured/drug effects; Breast Neoplasms/pathology; Ovarian Neoplasms/pathology; Prostatic Neoplasms/pathology; Phenothiazines/*chemistry/pharmacology; Mustard Compounds/*chemistry/pharmacology; Melanoma/pathology; Leukemia/pathology; Kidney Neoplasms/pathology; Central Nervous System Neoplasms/pathology; Carcinoma, Non-Small-Cell Lung/pathology; Antineoplastic Agents, Alkylating/*chemistry/pharmacology},
	year = {1999},
	eissn = {1791-7530},
	pages = {1859-1864}
}

@article{MTMT:1637992,
	title = {Anti-psychotic drugs reverse multidrug resistance of tumor cell lines and human AML cells ex-vivo},
	url = {https://m2.mtmt.hu/api/publication/1637992},
	author = {Szabó, Diána and Szabó, Gábor and Ocsovszki, Imre and Aszalos, A and Molnár, József},
	doi = {10.1016/S0304-3835(99)00020-8},
	journal-iso = {CANCER LETT},
	journal = {CANCER LETTERS},
	volume = {139},
	unique-id = {1637992},
	issn = {0304-3835},
	year = {1999},
	eissn = {1872-7980},
	pages = {115-119},
	orcid-numbers = {Ocsovszki, Imre/0000-0003-1290-996X}
}

@article{MTMT:1158097,
	title = {Nitric oxide production and MDR expression by human brain endothelial cells},
	url = {https://m2.mtmt.hu/api/publication/1158097},
	author = {Mándi, Yvette and Ocsovszki, Imre and Szabó, Diána and Nagy, Z and Nelson, J and Molnár, József},
	journal-iso = {ANTICANCER RES},
	journal = {ANTICANCER RESEARCH},
	volume = {18},
	unique-id = {1158097},
	issn = {0250-7005},
	year = {1998},
	eissn = {1791-7530},
	pages = {3049-3052},
	orcid-numbers = {Mándi, Yvette/0000-0003-4729-2445; Ocsovszki, Imre/0000-0003-1290-996X}
}

@article{MTMT:1158095,
	title = {Multidrug resistance reversal in mouse lymphoma cells by heterocyclic compounds},
	url = {https://m2.mtmt.hu/api/publication/1158095},
	author = {Molnár, József and Szabó, Diána and Mándi, Yvette and Mucsi, I and Fischer, J and Varga, A and Konig, S and Motohashi, N},
	journal-iso = {ANTICANCER RES},
	journal = {ANTICANCER RESEARCH},
	volume = {18},
	unique-id = {1158095},
	issn = {0250-7005},
	year = {1998},
	eissn = {1791-7530},
	pages = {3033-3038},
	orcid-numbers = {Mándi, Yvette/0000-0003-4729-2445}
}

@{MTMT:2515778,
	title = {Effect of some new 3-benzazepines on plasmid DNA , mdr p-glycoprotein and reverse transcriptase of leukaemia},
	url = {https://m2.mtmt.hu/api/publication/2515778},
	author = {Molnár, József and Szabó, Diána and Miskolci, Cs and Nacsa, J and Kawase, M and Saito, S and Motohashi, N},
	booktitle = {Non antibiotics: A New Class of Unrecognised Antimicrobics},
	unique-id = {2515778},
	year = {1998},
	pages = {272-280}
}

@article{MTMT:1862587,
	title = {The inhibition of SOS-responses and MDR by phenothiazine-metal complexes.},
	url = {https://m2.mtmt.hu/api/publication/1862587},
	author = {Nacsa, J and Nagy, L and Sharples, D and Hever, A and Szabó, Diána and Ocsovszki, Imre and Varga, A and Konig, S and Molnár, József},
	journal-iso = {ANTICANCER RES},
	journal = {ANTICANCER RESEARCH},
	volume = {18},
	unique-id = {1862587},
	issn = {0250-7005},
	abstract = {The gene of multidrug resistance (mdr) is inducible by different environmental stresses (SOS gene). We tested the inhibitory action of some new metal complexes of phenothiazines on megacin encoding bacterial gene induced by mitomycin-C as an example of "SOS induction" and on efflux pump of mouse lymphoma cells. The interaction of compounds to DNA was measured by thermal stability of DNA. It was found that metal co-ordination complexes of trifluoperazine (TFP) and chlorpromazine (CPZ) added before mitomycin administration have an inhibitory action on megacine induction. The TFP-V(IV) complex was effective at a lower concentration than TFP alone. The inhibitory effect of some metal coordinating complexes (TFP-Cu(II) and TFP- V(IV)) exceeded the action of TFP alone on efflux pumps. We propose that these compounds can form a complex with the regulatory protein or DNA resulting in the inhibition of SOS response and inhibit the mdr function by inactivating the P-glycoprotein as well.},
	keywords = {Animals; MICE; Drug Resistance, Multiple/*genetics; Mitomycin/pharmacology; SOS Response (Genetics)/*drug effects; Phenothiazines/chemistry/*pharmacology; P-Glycoprotein/biosynthesis; Metals/chemistry/*pharmacology; Megacins/biosynthesis; Lymphoma, T-Cell/metabolism; Gene Expression Regulation, Bacterial/*drug effects; DNA, Neoplasm/drug effects/metabolism; DNA, Bacterial/drug effects/metabolism; Bacillus megaterium/drug effects/metabolism; Antibiotics, Antineoplastic/pharmacology},
	year = {1998},
	eissn = {1791-7530},
	pages = {3093-3098},
	orcid-numbers = {Ocsovszki, Imre/0000-0003-1290-996X}
}