TY - JOUR AU - Misof, Barbara M. AU - Fratzl-Zelman, Nadja TI - Bone Quality and Mineralization and Effects of Treatment in Osteogenesis Imperfecta JF - CALCIFIED TISSUE INTERNATIONAL J2 - CALCIFIED TISSUE INT PY - 2024 PG - 28 SN - 0171-967X DO - 10.1007/s00223-024-01263-8 UR - https://m2.mtmt.hu/api/publication/35321104 ID - 35321104 LA - English DB - MTMT ER - TY - JOUR AU - de Oliveira, Ana Clara AU - Macedo, Ana Paula AU - Shimano, Antonio Carlos TI - Effects of Cannabidiol on Bone Quality in Ovariectomized Rats JF - CALCIFIED TISSUE INTERNATIONAL J2 - CALCIFIED TISSUE INT PY - 2024 PG - 12 SN - 0171-967X DO - 10.1007/s00223-024-01281-6 UR - https://m2.mtmt.hu/api/publication/35291444 ID - 35291444 LA - English DB - MTMT ER - TY - JOUR AU - Sun, Ting AU - Tie, Xin AU - Liu, Lu AU - Liu, Hongdie AU - Tian, Li TI - Saturation Effect of Lipid Accumulation Product (LAP) Index on Spinal Bone Mineral Density: A Population-Based Study JF - CALCIFIED TISSUE INTERNATIONAL J2 - CALCIFIED TISSUE INT PY - 2024 PG - 8 SN - 0171-967X DO - 10.1007/s00223-024-01278-1 UR - https://m2.mtmt.hu/api/publication/35278054 ID - 35278054 LA - English DB - MTMT ER - TY - JOUR AU - Huang, H. AU - Chen, J. AU - Lin, X. AU - Lin, Z. TI - Morinda Officinalis Polysaccharides Inhibit Osteoclast Differentiation by Regulating miR-214-3p/NEDD4L in Postmenopausal Osteoporosis Mice JF - CALCIFIED TISSUE INTERNATIONAL J2 - CALCIFIED TISSUE INT PY - 2024 SN - 0171-967X DO - 10.1007/s00223-024-01271-8 UR - https://m2.mtmt.hu/api/publication/35262049 ID - 35262049 N1 - Rehabilitation Department, Zhongshan Hospital, Xiamen University, Fujian, Xiamen, 361004, China Xiamen Humanity Rehabilitation Hospital, No. 3775 Xianyue Rd, Xiamen, 361006, China Export Date: 12 September 2024 CODEN: CTIND Correspondence Address: Huang, H.; Rehabilitation Department, Fujian, China; email: xmzshui@163.com AB - To investigate the potential mechanism of Morinda officinalis F. C. How polysaccharides (MOPs) in regulating osteoclast differentiation and apoptosis through miR-214-3p and its target protein. Ovariectomy was performed in 8-week female C57BL6 mice to establish the postmenopausal osteoporosis (PMOP) model. Mice were treated immediately with 500 mg/kg of MOPs (prevention group); others were treated 2 weeks after operation (treatment group). Left femur bone mineral density (BMD) was examined. RAW264.7 cells were administered with receptor activator of NF-κB ligand (RANKL) to establish the osteoclast (OC) model and treated with serum containing 1 or 2 g/kg of MOPs. Apoptosis-related indexes, miR-214-3p, and Expressed Developmentally Down-regulated 4-Like (NEDD4L) were detected by western blot, quantitative real-time-reverse transcription polymerase chain reaction (qRT-PCR), and flow cytometry. OC received a miR-214-3p inhibitor or NEDD4L small interfering RNA (siRNA). MOPs reversed the PMOP-induced changes in bones. Compared with the RANKL group, MOPs increased the apoptosis and related markers in OCs. MOPs decreased the femur miR-214-3p of PMOP mice (P < 0.001). Higher concentrations of MOPs reversed the upregulation of miR-214 mRNA in OCs (P < 0.001). miR-214-3p inhibitor increased the expression of Bax and CC3 (P < 0.01) and decreased the expression of Bcl-2 (P < 0.05). NEDD4L is targeted by miR-214. NEDD4L was upregulated in the RANKL + MOPs group (P < 0.01). miR-214-3p inhibitor increased the upregulation of NEDD4L induced by MOPs (P < 0.05). siRNA NEDD4L significantly reversed the inhibition of MOPs on osteoclast differentiation with miR-214-3p inhibitor (P < 0.01). MOPs effectively prevent PMOP by inhibiting osteoclastogenesis and inducing OC apoptosis through the miR-214-3p/NEDD4L pathway. © The Author(s) 2024. LA - English DB - MTMT ER - TY - JOUR AU - Zhang, Naidan AU - Ji, Chaixia AU - Liu, Li AU - Ye, Ermei AU - Yuan, Chengliang TI - The Causal Relationship between PCSK9 Inhibitors and Osteoporosis Based on Drug-Targeted Mendelian Combined Mediation Analysis JF - CALCIFIED TISSUE INTERNATIONAL J2 - CALCIFIED TISSUE INT PY - 2024 PG - 10 SN - 0171-967X DO - 10.1007/s00223-024-01228-x UR - https://m2.mtmt.hu/api/publication/34963414 ID - 34963414 LA - English DB - MTMT ER - TY - JOUR AU - Khuc, Khiem AU - des Bordes, Jude AU - Ogunwale, Abayomi AU - Madel, Maria-Bernadette AU - Ambrose, Catherine AU - Schulz, Paul AU - Elefteriou, Florent AU - Schwartz, Ann AU - Rianon, Nahid J. TI - Protective Effects of β-Blockers on Bone in Older Adults with Dementia JF - CALCIFIED TISSUE INTERNATIONAL J2 - CALCIFIED TISSUE INT PY - 2024 PG - 9 SN - 0171-967X DO - 10.1007/s00223-024-01221-4 UR - https://m2.mtmt.hu/api/publication/34955462 ID - 34955462 LA - English DB - MTMT ER - TY - JOUR AU - Arundel, Paul AU - Bishop, Nick TI - Medical Management for Fracture Prevention in Children with Osteogenesis Imperfecta JF - CALCIFIED TISSUE INTERNATIONAL J2 - CALCIFIED TISSUE INT PY - 2024 PG - 16 SN - 0171-967X DO - 10.1007/s00223-024-01202-7 UR - https://m2.mtmt.hu/api/publication/34939273 ID - 34939273 LA - English DB - MTMT ER - TY - JOUR AU - Hill, Claire L. AU - Ford, Davina AU - Baker, Jill TI - Optimising Health-Related Quality of Life in Children With Osteogenesis Imperfecta JF - CALCIFIED TISSUE INTERNATIONAL J2 - CALCIFIED TISSUE INT PY - 2024 PG - 19 SN - 0171-967X DO - 10.1007/s00223-024-01205-4 UR - https://m2.mtmt.hu/api/publication/34939272 ID - 34939272 LA - English DB - MTMT ER - TY - JOUR AU - Shih, Jen-Ta AU - Tan, Timothy L. AU - Shen, Pei-Hung AU - Yeh, Tsu-Te AU - Wu, Chia-Chun AU - Pan, Ru-Yu AU - Chien, Wu-Chien AU - Chung, Chi-Hsiang AU - Wang, Sheng-Hao TI - Postoperative Bisphosphonates Use is Associated with Reduced Adverse Outcomes After Primary Total Joint Arthroplasty of Hip and Knee: A Nationwide Population-Based Cohort Study JF - CALCIFIED TISSUE INTERNATIONAL J2 - CALCIFIED TISSUE INT PY - 2024 PG - 10 SN - 0171-967X DO - 10.1007/s00223-024-01192-6 UR - https://m2.mtmt.hu/api/publication/34757284 ID - 34757284 LA - English DB - MTMT ER - TY - JOUR AU - Bosman, A. AU - Appelman-Dijkstra, N. M. AU - Boot, A. M. AU - de Borst, M. H. AU - van de Ven, A. C. AU - de Jongh, R. T. AU - Bokenkamp, A. AU - van den Bergh, J. P. AU - van der Eerden, B. C. J. AU - Zillikens, M. C. TI - Disease Manifestations and Complications in Dutch X-Linked Hypophosphatemia Patients JF - CALCIFIED TISSUE INTERNATIONAL J2 - CALCIFIED TISSUE INT PY - 2024 PG - 12 SN - 0171-967X DO - 10.1007/s00223-023-01172-2 UR - https://m2.mtmt.hu/api/publication/34631367 ID - 34631367 LA - English DB - MTMT ER -