@article{MTMT:34747654,
	title = {Limosilactobacillus reuteri peptidoglycan alleviates aflatoxin B1-induced toxicity through adsorbing toxins and improving growth, antioxidant status, immunity and liver pathological changes in chicks},
	url = {https://m2.mtmt.hu/api/publication/34747654},
	author = {Zhu, F.H. and Chen, X.Y. and Hou, L.L. and Dong, J.H. and Liu, H.W. and Zhu, L.Q. and Chen, F.},
	doi = {10.1080/00071668.2024.2316228},
	journal-iso = {BRIT POULTRY SCI},
	journal = {BRITISH POULTRY SCIENCE},
	unique-id = {34747654},
	issn = {0007-1668},
	year = {2024},
	eissn = {1466-1799}
}

@article{MTMT:34666471,
	title = {Holo-analysis of the effects of xylo-oligosaccharides on broiler chicken performance},
	url = {https://m2.mtmt.hu/api/publication/34666471},
	author = {Morgan, N. K. and Kim, E. and Gonzalez-Ortiz, G.},
	doi = {10.1080/00071668.2023.2280963},
	journal-iso = {BRIT POULTRY SCI},
	journal = {BRITISH POULTRY SCIENCE},
	unique-id = {34666471},
	issn = {0007-1668},
	keywords = {ENZYMES; OLIGOSACCHARIDE; Broiler; XYLAN; Prebiotic; fibre},
	year = {2024},
	eissn = {1466-1799}
}

@article{MTMT:34758676,
	title = {Disturbance of mitochondrial dynamics in myocardium of broilers with pulmonary hypertension syndrome},
	url = {https://m2.mtmt.hu/api/publication/34758676},
	author = {Zhang, W. and Li, M. and Ye, X. and Jiang, M. and Wu, X. and Tang, Z. and Hu, L. and Zhang, H. and Li, Y. and Pan, J.},
	doi = {10.1080/00071668.2024.2308277},
	journal-iso = {BRIT POULTRY SCI},
	journal = {BRITISH POULTRY SCIENCE},
	volume = {65},
	unique-id = {34758676},
	issn = {0007-1668},
	abstract = {1. The following study investigated the relationship between pulmonary hypertension syndrome (PHS) and mitochondrial dynamics in broiler cardiomyocytes. 2. An animal model for PHS was established by injecting broiler chickens with CM-32 cellulose particles. Broiler myocardial cells were cultured under hypoxic conditions to establish an in vitro model. The ascites heart index, histomorphology, mitochondrial ultrastructure, and mitochondrial dynamic-related gene and protein expression were evaluated. 3. The myocardial fibres from PHS broilers had wider spaces and were wavy and twisted and the number of mitochondria increased. Compared with the control group, the gene and protein expression levels were decreased for Opa1, Mfn1, and Mfn2 in the myocardium of PHS broilers. The gene and protein expression was significantly increased for Drp1 and Mff. 4. This study showed that PHS in broilers may cause myocardial mitochondrial dysfunction, specifically by diminishing mitochondrial fusion and enhancing fission, causing disturbances in the mitochondrial dynamics of the heart. © 2024 British Poultry Science Ltd.},
	keywords = {HEART; HYPOXIA; mitochondrial dynamics; broilers; pulmonary hypertension syndrome},
	year = {2024},
	eissn = {1466-1799},
	pages = {154-164}
}

@article{MTMT:34461533,
	title = {Growth, not digestibility, in chickens receiving reduced-protein diets is independent of non-specific amino-nitrogen sources when the essential-to-total-nitrogen ratio is constant and lower than 50%},
	url = {https://m2.mtmt.hu/api/publication/34461533},
	author = {Olukosi, O. A. and Lin, Y.},
	doi = {10.1080/00071668.2023.2272973},
	journal-iso = {BRIT POULTRY SCI},
	journal = {BRITISH POULTRY SCIENCE},
	unique-id = {34461533},
	issn = {0007-1668},
	abstract = {1. A 21 d experiment was conducted to investigate whether growth performance and coefficients of amino acids digestibility (cAID) in broilers receiving reduced-protein diets supplemented with different non-essential amino acids (NEAA) were dependent on supplemented NEAA in diets with the same essential-to-total N (eN-to-tN) ratio kept at <50%.2. The experiment used 240 male broiler chicks, allocated to eight treatments with six replicate pens per treatment, and five chicks per replicate. The diets were either adequate in protein diet (PC), reduced protein (NC) diet or the NC diet supplemented with Gly, Gln, Ser, Ala, Gly + Ser or Ala + Ser. Digesta from the distal half of the ileum were collected on d 21. Tissue samples were collected for analysis for gene expression of protein synthesis and degradation (pectoralis major and liver) and peptide and AA transporters (jejunum).3. The treatments had no effects on growth performance. Generally, cAID was greater (P < 0.05) in NC compared to the PC diet. Individual supplementation of the NC diet with Gly, Gln, Ser, Ala or Ala+Ser increased (P < 0.01) cAID of Cys compared to the PC diet. There were no treatment effects on mRNA levels for the AA or peptide transporters in the jejunum. Supplementation of the NC diet with Gln, Ser, Ala, or Gly + Ser produced an upward expression (P < 0.05) of S6 kinase in the liver compared to PC and NC. In addition, there was greater (P < 0.05) expression of TRIM36 in the pectoralis major of broiler chickens receiving the NC diet supplemented with Gly.4. When reduced-protein diets have an eN-to-tN ratio of <50% and the ratio is kept constant in all the diets, growth performance response was independent of the source of non-specific amino-N, but the treatments may influence ileal digestibility of individual AA.},
	keywords = {DIGESTIBILITY; Growth performance; Broiler chickens; non-essential amino acids; Reduced-protein; essential-to-total-nitrogen},
	year = {2023},
	eissn = {1466-1799}
}

@article{MTMT:34246638,
	title = {Adenovirus type D and type E infection in broiler chickens: the effect on CD4 and CD8 T cell response, cytokines expression and their immunopathology},
	url = {https://m2.mtmt.hu/api/publication/34246638},
	author = {Abdel-Alim, G. A. and Aly, S. M. and Khattab, M. S. and Badawy, A. M. and Naguib, M. G. and Abdelhamid, T. M. and Hussein, H. A. and Morsy, E. A.},
	doi = {10.1080/00071668.2023.2248586},
	journal-iso = {BRIT POULTRY SCI},
	journal = {BRITISH POULTRY SCIENCE},
	unique-id = {34246638},
	issn = {0007-1668},
	abstract = {1. A total of 150-day-old chicks were divided into three groups of 50 birds (G1-G3); G1 and G2 were orally inoculated at 1-day old with 0.5 ml of 107 TCID50/ml FAdV-D serotype 2 (MT386509.1) and FAdV-E serotype 8a (MW847902), respectively, and G3 was blank control group.2. Cell-mediated immune response was evaluated by detection of CD4, CD8 T lymphocytes and the mRNA expression of IL6 and IL8 in the chicken spleen using q-PCR. Additionally, immunopathology was performed at 3, 5 and 7 day post infection (dpi) and weekly until the end of the experiment.3. Results revealed that transcription of inflammatory cytokines (IL6, IL8) was up regulated in the spleen of FAdV type D and type E infected chickens at various time points relative to the control group. A marked decrease in the number of CD4 and CD8 T lymphocytes at 5 and 7 dpi in G1 of chickens infected with FAdV type D. Whereas, in chickens infected with FAdV type E, the CD4 and CD8 T lymphocytes were markedly decreased at 7 dpi.4. In contrast, there were no significant differences in humoral immune responses against NDV vaccine in (G1 and G2) at different intervals post-vaccination compared to the control group. The histopathology of the bursa, thymus, and spleen in the infected groups showed lymphocytolysis with severe reticular cells hyperplasia and lymphoid depletion.5. In conclusion, fowl adenovirus types D and E have an immunosuppressive effect in broilers which may be considered one of the main causes of the continuous co-infections with other viruses reported in the field during the last 10 years.},
	keywords = {HEPATITIS; Infections; immunosuppression; Adenovirus; CHALLENGE; broilers},
	year = {2023},
	eissn = {1466-1799}
}

@article{MTMT:34236112,
	title = {Thyroid hormone-responsive protein mediates the response of chicken liver to fasting mainly through the cytokine-cytokine receptor interaction pathway},
	url = {https://m2.mtmt.hu/api/publication/34236112},
	author = {Mu, J. and Zhou, X. and Xing, Y. and Zhang, M. and Zhang, J. and Li, F. and Ge, J. and Zhao, M. and Liu, L. and Gong, D. and Geng, T.},
	doi = {10.1080/00071668.2023.2246135},
	journal-iso = {BRIT POULTRY SCI},
	journal = {BRITISH POULTRY SCIENCE},
	unique-id = {34236112},
	issn = {0007-1668},
	abstract = {1. The objective of this study was to explore the mediating role of thyroid hormone-responsive protein (THRSP) in the response of chicken liver to fasting.2. A batch of 7-d-old chicks with similar body weights were randomly divided into the control group and the fasting group (n = 10). The control group was fed ad libitum, while the test group fasted for 24 h. The liver and pectoral muscle tissues were collected. Chicken primary hepatocytes or myocytes were treated with different concentrations of thyroxine, glucose, insulin, oleic acid and palmitic acid, separately. Chicken primary hepatocytes were transfected with THRSP overexpression vector vs. empty vector, and the cells were used for transcriptome analysis. The mRNA expression of THRSP and other genes was determined by quantitative PCR.3. The expression of THRSP in chicken liver and pectoral muscle tissues was significantly inhibited by fasting (P < 0.05). In chicken primary hepatocytes, the expression of THRSP was significantly induced by thyroxine (0.25, 0.5, 1 mmol/l), glucose (50, 100 mmol/l), and insulin (20 nmol/l), and was significantly inhibited by palmitic acid (0.125, 0.25 mmol/l). In the myocytes, expression of THRSP was significantly induced by thyroxine (0.25, 0.5, 1 mmol/l), glucose (50 mmol/l) and oleic acid (0.125, 0.25 mmol/l), was significantly inhibited by insulin (5 nmol/l) and was not significantly affected by palmitic acid.4. Transcriptome analysis showed that overexpression of THRSP significantly affected the expression of 1411 DEGs, of which 1007 were up-regulated and 404 were down-regulated. The GO term and KEGG pathway enrichment analyses showed that these DEGs were mainly enriched in the interaction between cytokine and cytokine receptor and its regulation and signal transduction, cell growth and apoptosis and its regulation, immune response and retinol metabolism.5. In conclusion, the THRSP gene mediates biological effects of fasting by influencing the expressional regulation of the genes related to biological processes such as cytokine-cytokine receptor interaction, cell growth and apoptosis, immune response, retinol metabolism, including TGM2, HSD17B2, RUNX3, IRF1, ANKRD6, UPP2, IKBKE, and PYCR1 genes, in chicken liver.},
	keywords = {cytokine; NUTRITION; POULTRY; immune response; Cell growth; THRSP},
	year = {2023},
	eissn = {1466-1799}
}

@article{MTMT:34108444,
	title = {The British Ixworth: Individual growth and egg production of a purebred dual-purpose chicken},
	url = {https://m2.mtmt.hu/api/publication/34108444},
	author = {Becker, S. and Büscher, W. and Tiemann, I.},
	doi = {10.1080/00071668.2023.2246142},
	journal-iso = {BRIT POULTRY SCI},
	journal = {BRITISH POULTRY SCIENCE},
	unique-id = {34108444},
	issn = {0007-1668},
	year = {2023},
	eissn = {1466-1799},
	orcid-numbers = {Becker, S./0009-0005-8949-4717; Tiemann, I./0000-0002-3607-4453}
}

@article{MTMT:33966173,
	title = {Effects of access to feed, water, and a competitive exclusion product in the hatcher on some immune traits and gut development in broiler chickens},
	url = {https://m2.mtmt.hu/api/publication/33966173},
	author = {Boyner, M. and Ivarsson, E. and Wattrang, E. and Sun, L. and Wistedt, A. and Wall, H.},
	doi = {10.1080/00071668.2022.2163152},
	journal-iso = {BRIT POULTRY SCI},
	journal = {BRITISH POULTRY SCIENCE},
	unique-id = {33966173},
	issn = {0007-1668},
	abstract = {1. This study evaluated the effect of access to feed, water, and the competitive exclusion (CE) product Broilact((R)), administered in the hatcher, on broiler performance, caecal microbiota development, organ development, intestinal morphology, serum levels of IgY and vaccine-induced antibody responses.2. In total, 250 chicks were hatched in a HatchCare (TM) hatcher and divided into four groups, given access to feed, water and the CE product sprayed on the chicks (CEs); access to feed, water, and the CE product in water (CEw); access to feed and water (Cpos); or no access to feed and water (Cneg) in the hatcher.3. At the research facility, 10 chicks per hatching treatment were euthanised for organ measurements. The remaining 200 chicks were randomly distributed to 20 pens. On d 11, all birds were vaccinated against avian pneumovirus (APV). Three focal birds per pen were blood-sampled weekly for quantification of IgY and serum antibodies to APV. On d 11 and 32, two birds per replicate pen were euthanised for organ measurements and sample collection. Feed intake and body weight were recorded weekly.4. Delayed access to feed and water reduced weight gain and feed intake early in life. At the end of the study, no differences in body weight remained.5. There were some early effects on organs, with depressed intestinal development and higher relative gizzard weight for the Cneg group at placement. No treatment effects on the immune traits measured were detected.6. The relative abundance of seven bacterial genera differed between treatment groups at d 11 of age. The results suggested that chickens are capable of compensating for 40 h feed and water deprival post-hatch. Provision of Broilact((R)) did not have any persistent performance-enhancing properties, although different outcomes under rearing conditions closer to commercial production cannot be ruled out.},
	keywords = {IMMUNOGLOBULIN; VACCINE; microbiology; Histology; Probiotics; hatching},
	year = {2023},
	eissn = {1466-1799}
}

@article{MTMT:33882844,
	title = {Co-expression analysis of long non-coding RNAs and mRNAs involved in intramuscular fat deposition in Muchuan black-bone chicken},
	url = {https://m2.mtmt.hu/api/publication/33882844},
	author = {Yu, S. and Wang, G. and Liao, J. and Shen, X. and Chen, J. and Chen, X.},
	doi = {10.1080/00071668.2022.2162370},
	journal-iso = {BRIT POULTRY SCI},
	journal = {BRITISH POULTRY SCIENCE},
	unique-id = {33882844},
	issn = {0007-1668},
	abstract = {1. The intramuscular fat (IMF) content in meat products is positively correlated with meat quality, making it an important consumer trait. Long non-coding RNAs (lncRNAs) play central roles in regulating various biological processes, but little is currently known about the mechanisms by which they regulate IMF deposition in chickens.2. This study sampled the breast muscles of chickens with high (H) and low (L) IMF content and constructed six small RNA libraries. High-throughput sequencing technology was used to pro?le the breast muscle transcriptome (lncRNA and mRNA) and to identify the differentially expressed lncRNAs (DELs) and mRNAs (DEGs) between the H and L groups. In total, 263 DELs (118 up-regulated and 145 down-regulated lncRNAs) and 443 DEGs (203 up-regulated and 240 down-regulated genes) were identified between the two groups.3. To analyse the DELs-DEGs interaction network, co-expression analysis was conducted to identify lncRNA-mRNA pairs. In total, 19270 lncRNA/mRNA pairs were identified, including 16 398 significant correlation pairs that presented as positive and 2872 pairs that presented as negative. The lncRNA - mRNA network comprised 263 lncRNA nodes and 440 mRNA nodes.4. Pathway analysis, using the Kyoto Encyclopedia of Genes and Genomes, indicated pathways associated with fat deposition and lipid metabolism such as the MAPK, PPAR, GnRH, ErbB and calcium signalling pathways, fatty acid elongation and fatty acid metabolism. Overall, the study identified potential candidate lncRNAs, genes and regulatory networks associated with chicken IMF deposition. These findings provide new insights to help clarify the regulatory mechanisms of IMF deposition in chickens which can be used to improve the IMF content in poultry.},
	keywords = {GENE; Meat quality; chicken; Intramuscular fat; LncRNA; RNA sequencing},
	year = {2023},
	eissn = {1466-1799}
}

@article{MTMT:33799065,
	title = {Effects of testis testosterone deficiency on gene expression in the adrenal gland and skeletal muscle of ducks},
	url = {https://m2.mtmt.hu/api/publication/33799065},
	author = {Wang, J. and Ma, S. and Wu, Q. and Xu, Q. and Zhang, R. and Bai, L. and Li, L. and Liu, H.},
	doi = {10.1080/00071668.2023.2176741},
	journal-iso = {BRIT POULTRY SCI},
	journal = {BRITISH POULTRY SCIENCE},
	unique-id = {33799065},
	issn = {0007-1668},
	abstract = {1. Testosterone has an anabolic effect on skeletal muscle. The testes produce most of the testosterone in vivo, while the adrenal glands contribute smaller amounts. When testis testosterone is deficient the adrenal gland increases steroid hormone synthesis, which is referred to as compensatory testicular adaptation (CTA). 2. To reveal the effects of testis testosterone deficiency on adrenal steroid hormones synthesis and skeletal muscle development, gene expression related to adrenal steroid hormones synthesis and skeletal muscle development were determined by RNA-seq. 3. The results showed that castrating male ducks had significant effects on their body weight but no significant impact on cross-sectional area (CSA) or density of pectoral muscle fibres. In skeletal muscle protein metabolism, expression levels of the catabolic gene atrogin1/MAFbx and the anabolic gene eEF2 were significantly higher, with concomitant increases after castration. The adrenal glands’ alteration of the steroid hormone 11β-hydroxylase (CYP11B1) was significantly lower following castration. 4. Expression pattern analysis showed that the adrenal glands’ glucocorticoid receptor (NR3C1/GR) had a potential regulatory relationship with the skeletal muscle-related genes (Pax7, mTOR, FBXO32, FOXO3, and FOXO4). 5. The data showed that castration affected muscle protein metabolism, adrenal steroid and testosterone synthesis. In addition, it was speculated that, after castration, steroid hormones produced by the adrenal gland could have a compensatory effect, which might mediate the changes in skeletal muscle protein metabolism and development. © 2023 British Poultry Science Ltd.},
	keywords = {HORMONES; skeletal muscle; duck; RNA-Seq; Testosterone deficiency},
	year = {2023},
	eissn = {1466-1799}
}