@article{MTMT:35270686,
	title = {Quality of Life After Endovascular Thrombectomy for Acute Ischemic Stroke in Northern Finland},
	url = {https://m2.mtmt.hu/api/publication/35270686},
	author = {Junttola, Ulla and Liisanantti, Janne and Isokangas, Juha-Matti and Kaakinen, Timo and Vakkala, Merja and Lahtinen, Sanna},
	doi = {10.1155/2024/6684746},
	journal-iso = {ACTA NEUROL SCAND},
	journal = {ACTA NEUROLOGICA SCANDINAVICA},
	volume = {2024},
	unique-id = {35270686},
	issn = {0001-6314},
	year = {2024},
	eissn = {1600-0404},
	orcid-numbers = {Liisanantti, Janne/0000-0002-5580-3447}
}

@article{MTMT:34977257,
	title = {Sleep Disturbance and Related Factors in the Patients with Relapsing-Remitting Multiple Sclerosis},
	url = {https://m2.mtmt.hu/api/publication/34977257},
	author = {Sempik, Izabela and Dziadkowiak, Edyta and Wieczorek, Malgorzata and Pokryszko-Dragan, Anna},
	doi = {10.1155/2024/6656571},
	journal-iso = {ACTA NEUROL SCAND},
	journal = {ACTA NEUROLOGICA SCANDINAVICA},
	volume = {2024},
	unique-id = {34977257},
	issn = {0001-6314},
	year = {2024},
	eissn = {1600-0404},
	orcid-numbers = {Dziadkowiak, Edyta/0000-0002-9618-9308}
}

@article{MTMT:34965495,
	title = {Increased <SUP>18</SUP>F-THK5351 Uptake at Bilateral Primary Motor Cortex in Patients with Progressive Pseudobulbar Palsy},
	url = {https://m2.mtmt.hu/api/publication/34965495},
	author = {Takahashi, Kensuke and Kurihara, Masanori and Ishibashi, Kenji and Komori, Yuta and Goto, Ryoji and Higashihara, Mana and Kameyama, Masashi and Hirano, Hirohiko and Maeda, Meiko Hashimoto and Watanabe, Rie and Ishii, Kenji and Iwata, Atsushi},
	doi = {10.1155/2024/4310875},
	journal-iso = {ACTA NEUROL SCAND},
	journal = {ACTA NEUROLOGICA SCANDINAVICA},
	volume = {2024},
	unique-id = {34965495},
	issn = {0001-6314},
	year = {2024},
	eissn = {1600-0404},
	orcid-numbers = {Kurihara, Masanori/0000-0002-8281-0634; Goto, Ryoji/0000-0002-1693-9915; Kameyama, Masashi/0000-0001-9496-2590}
}

@article{MTMT:34926784,
	title = {Joint Association of Low Nadir Serum Sodium and Potassium with Worse Outcomes after Ischemic Stroke},
	url = {https://m2.mtmt.hu/api/publication/34926784},
	author = {Feng, Zijuan and Chen, Ting and Liu, Peng and Zhang, Ziyi and Wang, Zhetao and Wang, Yanan and Song, Quhong and Ye, Chen and Liu, Ming and Zhang, Shuting},
	doi = {10.1155/2024/5541608},
	journal-iso = {ACTA NEUROL SCAND},
	journal = {ACTA NEUROLOGICA SCANDINAVICA},
	volume = {2024},
	unique-id = {34926784},
	issn = {0001-6314},
	year = {2024},
	eissn = {1600-0404},
	orcid-numbers = {Wang, Yanan/0000-0002-3089-9462; Ye, Chen/0000-0003-2969-5486}
}

@article{MTMT:34566742,
	title = {The Role of Biomarkers Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) and Vasoactive Intestinal Peptide (VIP) in Chronic and Episodic Migraines: A Meta-Analysis},
	url = {https://m2.mtmt.hu/api/publication/34566742},
	author = {Thapa, S. and Shah, S. and Bhattarai, A. and Yadav, R. and Yu, F. and Chand, S. and Li, J.},
	doi = {10.1155/2024/2954374},
	journal-iso = {ACTA NEUROL SCAND},
	journal = {ACTA NEUROLOGICA SCANDINAVICA},
	volume = {2024},
	unique-id = {34566742},
	issn = {0001-6314},
	abstract = {Background. Migraine is a neurological disorder that results in disability accumulation, and there are no blood-based markers for indicating migraine susceptibility. Here, we aimed to evaluate the possible biomarker role of neuropeptides, vasoactive intestinal peptide (VIP), and pituitary adenylate cyclase-activating polypeptide (PACAP) in chronic (CM) and episodic migraine (EM). Method. PubMed, medRxiv, and Google Scholar databases were searched up to the 7th of September 2022 using the search syntax to define all relevant articles addressing the plasma and serum levels of VIP and PACAP in migraineurs and controls. Concerning bias assessment, the risk of bias in nonrandomized studies-I (ROBINS-I) was assessed. Also, the standardized mean difference (SMD) was measured with a random effects model. Results. Five case-control studies with 503 migraine cases were included. CM patients had elevated VIP levels compared to controls (SMD=0.44, 95% CI 0.25-0.62, p<0.00001). In contrast, PACAP levels were lower in EM patients (SMD=-0.30, 95% CI -0.48 to -0.11, p=0.002). Overall, migraine cases had higher VIP levels (SMD=0.25, 95% CI 0.11-0.39, p=0.0006) but lower PACAP levels (SMD=-0.16, 95% CI -0.30 to -0.03, p=0.020) than controls. Conclusion. The results support the role of VIP and PACAP neuropeptides in migraine pathophysiology. CM patients have significantly higher serum VIP levels, while EM patients have lower serum PACAP levels compared to controls. Further studies should confirm these findings. © 2024 Sangharsha Thapa et al.},
	keywords = {Adult; Female; Male; NEUROPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE; review; human; controlled study; protein blood level; meta analysis; hypophysis adenylate cyclase activating polypeptide; EPISODIC MIGRAINE; transformed migraine},
	year = {2024},
	eissn = {1600-0404}
}

@article{MTMT:34877687,
	title = {Sociodemographic Factors, Nutritional Status, and Inflammatory Markers in Patients with Postural Orthostatic Tachycardia Syndrome},
	url = {https://m2.mtmt.hu/api/publication/34877687},
	author = {Tufvesson, Hanna and Hamrefors, Viktor and Roth, Bodil and Fedorowski, Artur and Ohlsson, Bodil},
	doi = {10.1155/2023/3992718},
	journal-iso = {ACTA NEUROL SCAND},
	journal = {ACTA NEUROLOGICA SCANDINAVICA},
	volume = {2023},
	unique-id = {34877687},
	issn = {0001-6314},
	abstract = {Objectives. Postural orthostatic tachycardia syndrome (POTS) is characterized by cardiovascular autonomic dysfunction of unknown etiology with high a prevalence of gastrointestinal symptoms. The aim of the present study was to examine sociodemographic, lifestyle, and nutritional factors as well as inflammatory markers in patients with POTS. Materials and Methods. Forty-three patients with POTS and 61 healthy controls completed questionnaires about sociodemographic factors, lifestyle habits, and gastrointestinal symptoms. Blood samples were analyzed for serum levels of cobalamins, folic acid, iron, total iron-binding capacity (TIBC), ferritin, sodium, potassium, magnesium, phosphorus, albumin, high-sensitive C-reactive protein (CRP), and 25-hydroxyvitamin D (25-OH vitamin D). Results. POTS patients were predominantly women with a lower education level and were more often working part-time, on sick leave, and living alone compared with healthy controls. They reported lower alcohol intake and physical activity levels than controls. The nutrient intake was in general similar in both groups, but POTS patients had a higher intake of different drinks and reported more gastrointestinal symptoms than controls. POTS was associated with higher CRP levels (beta: 1.370; 95% CI: 0.004-2.737; p=0.049), lower albumin levels (beta: -1.443; 95% CI: -2.648-(-0.238); p=0.019), and higher sodium levels (beta: 1.392; 95% CI: 0.559-2.225; p=0.001). Abdominal pain (p=0.004) and intestinal symptoms' influence on daily life (p=0.025) were negatively associated with albumin levels. Abdominal pain (p=0.011), vomiting and nausea (p=0.003), and intestinal symptoms' influence on daily life (p=0.026) were associated with higher sodium levels. Serum levels representing iron and vitamin metabolism were equal between groups. Conclusions. POTS is associated with poorer sociodemographic status, but malnutrition cannot explain POTS or related gastrointestinal symptoms. Higher CRP and lower albumin levels suggest low-grade inflammation as one possible etiological factor.},
	keywords = {BLOOD-VOLUME},
	year = {2023},
	eissn = {1600-0404},
	orcid-numbers = {Hamrefors, Viktor/0000-0002-8475-0866; Roth, Bodil/0000-0001-9745-652X; Fedorowski, Artur/0000-0002-5352-6327; Ohlsson, Bodil/0000-0002-9142-5244}
}

@article{MTMT:34628768,
	title = {Effect of Dual- versus Single-Antiplatelet Therapy on Early Neurological Deterioration in Minor Stroke of Undetermined Cause},
	url = {https://m2.mtmt.hu/api/publication/34628768},
	author = {Xu, Bingdong and Xin, Xiufeng and Ding, Yan and Xu, Anding and Zhang, Yusheng},
	doi = {10.1155/2023/5532467},
	journal-iso = {ACTA NEUROL SCAND},
	journal = {ACTA NEUROLOGICA SCANDINAVICA},
	volume = {2023},
	unique-id = {34628768},
	issn = {0001-6314},
	year = {2023},
	eissn = {1600-0404}
}

@article{MTMT:34585999,
	title = {Candidate Selection for Implantation: Noninvasive Predictors of Seizure Onset Zone Focality and Surgical Outcome in People with Drug-Resistant Epilepsy Evaluated by Intracranial Video-EEG Monitoring-A Retrospective Cohort Study},
	url = {https://m2.mtmt.hu/api/publication/34585999},
	author = {Jannone-Pedro, Nicolas and Hampel, Kevin G. and Garces-Sanchez, Mercedes and Conde-Sardon, Rebeca and Gutierrez-Martin, Antonio and Villanueva, Vicente},
	doi = {10.1155/2023/3455061},
	journal-iso = {ACTA NEUROL SCAND},
	journal = {ACTA NEUROLOGICA SCANDINAVICA},
	volume = {2023},
	unique-id = {34585999},
	issn = {0001-6314},
	abstract = {Objectives. People with drug-resistant epilepsy are potential candidates for epilepsy surgery, a subset of whom requires intracranial video-EEG monitoring (IVEM) to determine the seizure onset zone (SOZ). The purpose of this study is to investigate noninvasive predictors of SOZ focality and surgical outcome in order to optimise case selection for this procedure. Materials and Methods. We performed a retrospective cohort study of patients who underwent IVEM at our centre from January 2006 to July 2021. We applied a multivariate logistic regression model to estimate the effect of potential noninvasive data as influencing factors for both SOZ focality and surgical outcome. A focal SOZ included a sublobar onset on IVEM, and a good surgical outcome was defined as Engel class I. Results. A total of 783 underwent a presurgical evaluation, 102 of them with IVEM. Ninety-seven patients were included in the SOZ focality analysis, and 64 were included in the surgical outcome analysis. The presence of focal to bilateral tonic-clonic seizures (p=0.03) and generalised interictal epileptiform discharges (IEDs) during scalp EEG (p=0.02) predicted a nonfocal SOZ. A weekly (p=0.01) or daily seizure frequency (p<0.01), focal to bilateral tonic-clonic seizures (p=0.01), nonlesional MRI (p<0.01), and multifocal (p=0.02) or generalised IEDs (p<0.01) were associated with a poor surgical outcome. Conclusions. A high seizure frequency, positive history of focal to bilateral tonic-clonic seizures, nonlesional MRI, and generalised and multifocal IEDs are noninvasive factors that may aid in selecting candidates for IVEM.},
	year = {2023},
	eissn = {1600-0404}
}

@article{MTMT:34572643,
	title = {Neurofilament and Brain Atrophy and Their Association with Cognition in Multiple Sclerosis: A 10-Year Follow-Up Study},
	url = {https://m2.mtmt.hu/api/publication/34572643},
	author = {Bhan, A. and Jacobsen, C. and Dalen, I. and Alves, G. and Bergsland, N. and Myhr, K.-M. and Zetterberg, H. and Zivadinov, R. and Farbu, E.},
	doi = {10.1155/2023/7136599},
	journal-iso = {ACTA NEUROL SCAND},
	journal = {ACTA NEUROLOGICA SCANDINAVICA},
	volume = {2023},
	unique-id = {34572643},
	issn = {0001-6314},
	abstract = {Introduction. Cognitive impairment is an important contributor to disability in multiple sclerosis (MS). Disconnection of neuronal circuits due to axonal injury is probably an important underlying mechanism for this disability. Neurofilament light chain (NfL) is a neuron-specific constituent of axons and has gained increasing attention as a biomarker of axonal injury. Objective. To assess the association between NfL in serum (sNfL) and cerebrospinal fluid (cNfL) and cognitive function over 10 years and compare these associations with volumetric brain magnetic resonance imaging (MRI) measurements. Methods. Newly diagnosed MS patients were followed prospectively with baseline NfL and MRI as well as with clinical and cognitive assessments for up to 10 years. Results. Forty-one patients were included. Baseline sNfL correlated negatively with symbol digit modalities test (SDMT) at baseline (r=-0.45, p=0.005), year 5 (r=-0.41, p=0.017), and at year 10 (r=-0.52, p=0.008). Baseline cNfL correlated with baseline SDMT (r=-0.34, p=0.030) and SDMT at year 10 (r=-0.44, p=0.037). Baseline volumes of whole brain (r=0.476, p=0.002), gray matter (r=0.467, p=0.002), T1 (r=-0.627, p<0.001), and T2 lesion volumes (r=-0.475, p=0.002) correlated significantly with baseline SDMT. Longitudinal analyses showed that both MRI volumes and EDSS were associated with the rate of SDMT decline, whereas sNfL and cNfL were not. Conclusion. NfL levels measured in serum and cerebrospinal fluid were both associated with cognitive functioning in MS patients over a 10-year period from diagnosis. However, MRI volumes correlated strongly in addition to the rate of cognitive decline. © 2023 Alok Bhan et al.},
	keywords = {Adult; Female; Male; SERUM; ARTICLE; human; comparative study; disease association; controlled study; cohort analysis; clinical feature; nuclear magnetic resonance imaging; clinical article; cognition; cerebrospinal fluid; prospective study; MULTIPLE SCLEROSIS; BRAIN ATROPHY; follow up; Neurofilament; clinical assessment; cognitive defect; MILD COGNITIVE IMPAIRMENT; gray matter; nerve cell network; Demographics; AXONAL INJURY; neurofilament light chain; Symbol Digit Modalities Test; lesion volume; T1 weighted imaging; T2 weighted imaging},
	year = {2023},
	eissn = {1600-0404}
}

@article{MTMT:34309252,
	title = {Understanding the Cross-Talk between the Ceramide Biosynthetic Pathway and Mitochondrial Function in Multiple Sclerosis and Demyelinating Disorders},
	url = {https://m2.mtmt.hu/api/publication/34309252},
	author = {Amarjeet, Abhipsa and Babu, Raja and Mohapatra, Abhipsa and Pancholi, Bhaskaranand and Garabadu, Debapriya and Sharma, Anjali and Sharma, Ashwani and Azad, Md. A. K.},
	doi = {10.1155/2023/7398037},
	journal-iso = {ACTA NEUROL SCAND},
	journal = {ACTA NEUROLOGICA SCANDINAVICA},
	volume = {2023},
	unique-id = {34309252},
	issn = {0001-6314},
	abstract = {Myelin is a spiral compilation of uniformly thick membranes around the axon in an alternating fashion, and it is formed by a complicated process known as myelination. Myelin sheaths are responsible for various physiological functions such as metabolism, rapid nerve conduction, and maintaining ionic and water homeostasis in the brain. Lipid is one of the major components in the myelin, which includes cholesterol, ceramide, and their derivatives, such as galactosylceramide, sulfatide, and gangliosides. Ceramide and its derivatives are synthesised by various ceramide biosynthetic pathways such as de novo, salvage, sphingomyelinase, and recycling of exogenous ceramide. At an appropriate level, ceramide facilitates the development of the nervous system, cell proliferation, autophagy, and apoptosis, which are responsible for normal functioning, but when the level is altered from normal, it results in mitochondrial dysfunction or cell death through autophagy and apoptosis. The ceramide level increases, especially in the mitochondria. Ceramide level increases in response to oxidative stress which is mediated by inflammatory cytokines. Due to mitochondrial dysfunction, an energy-deficient condition is created because of disruption in the electron transport chain, which results in the death of neurons and glial cells, which subsequently cause demyelination and degeneration of axon. Losing myelin while axons remain relatively intact is the characteristic feature of demyelinating diseases. The primary element of demyelinating disorder is damage, malfunction, failure, or death of mitochondria. These disturbances may occur due to direct or indirect interaction of ceramide with mitochondria. There are several risk factors for demyelination, such as viruses, bacteria, fungi, trauma, obesity, vitamin D deficiency, and genetic and environmental factors. Thus, the review is mainly aimed towards the interaction between ceramide and mitochondria during demyelination.},
	year = {2023},
	eissn = {1600-0404}
}