@article{MTMT:37164127, title = {A Nationwide Study of Pyruvate Dehydrogenase Complex Deficiency in Sweden: Epidemiology, Genotype-Phenotype Correlations, and Survival}, url = {https://m2.mtmt.hu/api/publication/37164127}, author = {Savvidou, Antri and Sofou, Kalliopi and Thunstrom, Sofia and Ygberg, Sofia and Eklund, Erik A. and Naess, Karin and Kollberg, Gittan and Darin, Niklas}, doi = {10.1212/WNL.0000000000214924}, journal-iso = {NEUROLOGY}, journal = {NEUROLOGY}, volume = {106}, unique-id = {37164127}, issn = {0028-3878}, year = {2026}, eissn = {1526-632X} } @article{MTMT:37218982, title = {Characterizing Individuals Fulfilling Clinical Criteria for Limbic-Predominant Age-Related TDP-43 Encephalopathy in a Tertiary Memory Clinic}, url = {https://m2.mtmt.hu/api/publication/37218982}, author = {Groot, Colin and Calandri, Ismael L. and Bader, Ilse and Bocancea, Diana I. and de Bruin, Hannah and Carrigan, Maria and Collij, Lyduine E. and Duits, Flora H. and Kamps, Suzie and de Koning, Lotte A. and Lemstra, Afina W. and Mastenbroek, Sophie E. and Rikken, Roos M. and van Tol, Bastiaan G. J. and Vermeiren, Marie R. and Wesseling, Alex and Xia, Ye and Teunissen, Charlotte E. and van de Giessen, Elsmarieke and Barkhof, Frederik and Jonkman, Laura E. and de Boer, Casper and Rozemuller, Annemieke J. and Leeuwis, Anna E. and van der Vlies, Annelies E. and Tijms, Betty M. and van der Flier, Wiesje M. and Pijnenburg, Yolande A. L. and Coomans, Emma M. and Ossenkoppele, Rik}, doi = {10.1212/WNL.0000000000214810}, journal-iso = {NEUROLOGY}, journal = {NEUROLOGY}, volume = {106}, unique-id = {37218982}, issn = {0028-3878}, year = {2026}, eissn = {1526-632X}, orcid-numbers = {Barkhof, Frederik/0000-0003-3543-3706} } @article{MTMT:37218984, title = {The Clinical Diagnosis of AD, LATE, and AD plus LATERelevant Considerations for Your Patients or Research Participants}, url = {https://m2.mtmt.hu/api/publication/37218984}, author = {Nelson, Peter T. and Jicha, Gregory A.}, doi = {10.1212/WNL.0000000000214919}, journal-iso = {NEUROLOGY}, journal = {NEUROLOGY}, volume = {106}, unique-id = {37218984}, issn = {0028-3878}, year = {2026}, eissn = {1526-632X} } @article{MTMT:37261227, title = {Influence of Decreased Kidney Function on Plasma Biomarkers of Neurodegenerative Disorders in Routine Care: Confirmation of the Interest of Ratios}, url = {https://m2.mtmt.hu/api/publication/37261227}, author = {Mondesert, Etienne and Cristol, Jean-Paul and Bargnoux, Anne-Sophie and Duchiron, Marie and Busto, Germain Ulysse and Hirtz, Christophe and Barnier-Figue, Genevieve and Perrein, Florence and Turpinat, Cedric and Jurici, Snejana and Gabelle, Audrey and Bennys, Karim and Lehmann, Sylvain and Delaby, Constance}, doi = {10.1212/WNL.0000000000214931}, journal-iso = {NEUROLOGY}, journal = {NEUROLOGY}, volume = {106}, unique-id = {37261227}, issn = {0028-3878}, year = {2026}, eissn = {1526-632X} } @article{MTMT:37287712, title = {Postapproval Study for Brain-Responsive Neurostimulation for Drug-Resistant Focal Epilepsy: Three-Year Efficacy and Interim Safety Results}, url = {https://m2.mtmt.hu/api/publication/37287712}, author = {Eliashiv, Dawn and Rao, Vikram R. and Jobst, Barbara C. and Szaflarski, Jerzy P. and Rolston, John D. and Kaye, Lesley C. and Ganguly, Taneeta Mindy and Bullinger, Katie and Dugan, Patricia C. and Burdette, David E. and Peters, Angela Y. and Sheikh, Atif and Haas, Kevin F. and Nair, Dileep R. and Mnatsakanyan, Lilit and Quraishi, Imran H. and Bensalem-Owen, Meriem K. and Doherty, Michael J. and Razavi, Babak and Fisher, Tiffany L. and Skidmore, Christopher and Modur, Pradeep N. and Constantino, Tawnya M. and Salanova, Vicenta and Cole, Andrew J. and Taraschenko, Olga and Rivera-Cruz, Angelica and Wheless, James W. and Tandon, Nitin and Balabanov, Antoaneta and Aboumatar, Sami and Fried, Itzhak and Drees, Cornelia and Shin, Hae Won and Jaisani, Zeenat and MacIver, Stephanie E. and Patra, Sanjay E. and Chang, Edward F. and Willie, Jon T. and Gwinn, Ryder and Stoub, Travis and Stern, John M. and Crabtree, Tami and Seale, Cairn G. and McFadden, Sharon C. and Norman, Jacob F. and Johnson, Lise and Morrell, Martha J.}, doi = {10.1212/WNL.0000000000214875}, journal-iso = {NEUROLOGY}, journal = {NEUROLOGY}, volume = {106}, unique-id = {37287712}, issn = {0028-3878}, year = {2026}, eissn = {1526-632X} } @article{MTMT:37222156, title = {Functional Outcome Following Blood Pressure Drops Within 24 Hours After Successful Mechanical Thrombectomy}, url = {https://m2.mtmt.hu/api/publication/37222156}, author = {Riegler, Christoph and Nelde, Alexander and Bergstrom, Wilma H. and Von Rennenberg, Regina and Bollweg, Kerstin and Meisel, Andreas and Scheitz, Jan F. and Scheel, Michael and Siebert, Eberhard and Audebert, Heinrich J. and Meisel, Christian and Nolte, Christian H.}, doi = {10.1212/WNL.0000000000214831}, journal-iso = {NEUROLOGY}, journal = {NEUROLOGY}, volume = {106}, unique-id = {37222156}, issn = {0028-3878}, year = {2026}, eissn = {1526-632X} } @article{MTMT:37261697, title = {Characterizing Heterogeneity in Brain Morphology in Traumatic Brain Injury Using Normative Modeling}, url = {https://m2.mtmt.hu/api/publication/37261697}, author = {Mitchell, Jake and McDonald, Stuart J. and Law, Meng and O'Brien, Terence J. and Westlye, Lars T. and Caeyenberghs, Karen and Newcombe, Virginia and Sharp, David J. and Mohamed, Abdalla Z. and Bigler, Erin D. and Amiri, Houshang and Irimia, Andrei and Mondello, Stefania and Thomopoulos, Sophia I. and Van Horn, John Darrell and Tate, David F. and Wilde, Elisabeth A. and Haberg, Asta K. and Monti, Martin M. and Edelstein, Rachel and Adamson, Maheen M. and Walker, William C. and Dams-O'Connor, Kristen and Deutscher, Evelyn M. and Dobryakova, Ekaterina and Hellstrom, Torgeir and Dennis, Emily L. and Thompson, Paul M. and Hillary, Frank G. and Olsen, Alexander and Ponsford, Jennie L. and Shultz, Sandy R. and Spitz, Gershon}, doi = {10.1212/WNL.0000000000214741}, journal-iso = {NEUROLOGY}, journal = {NEUROLOGY}, volume = {106}, unique-id = {37261697}, issn = {0028-3878}, year = {2026}, eissn = {1526-632X}, orcid-numbers = {Mondello, Stefania/0000-0002-8587-3614} } @article{MTMT:37276025, title = {Long-Term Exposure to Ambient Air Pollution and Incident Amyotrophic Lateral Sclerosis A Prospective Cohort Analysis of the UK Biobank}, url = {https://m2.mtmt.hu/api/publication/37276025}, author = {Chalitsios, Christos V. and Rudolf, Oliver and Gao, Jiali and Turner, Martin R. and Thompson, Alexander G.}, doi = {10.1212/WNL.0000000000214858}, journal-iso = {NEUROLOGY}, journal = {NEUROLOGY}, volume = {106}, unique-id = {37276025}, issn = {0028-3878}, year = {2026}, eissn = {1526-632X} } @article{MTMT:37292880, title = {Effect of Cognitive Reserve on Age at Symptom Onset and Cognitive Decline in Individuals With Dominantly Inherited Alzheimer Disease}, url = {https://m2.mtmt.hu/api/publication/37292880}, author = {Llibre-Guerra, Jorge J. and Lu, Ruijin and Clarens, Ma. Florencia and Liu, Ian and Renton, Alan and Ryan, Natalie S. and Goate, Alison M. and Aguillon, David and Allegri, Ricardo Francisco and Benzinger, Tammie L. S. and Berman, Sarah and Chhatwal, Jasmeer P. and Chrem Mendez, Patricio and Vigo, Gabriela and Cruchaga, Carlos and Day, Gregory S. and Farlow, Martin R. and Fox, Nick C. and Gordon, Brian Andrew and Hassenstab, Jason and Huey, Edward D. and Ibanez, Laura and Ikeuchi, Takeshi and Jucker, Mathias and Lee, Jae-Hong and Levey, Allan I. and Levin, Johannes and Niimi, Yoshiki and Perrin, Richard J. and Rosa-Neto, Pedro and Sanchez-Valle, Raquel and Schofield, Peter R. and Wang, Guoqiao and Li, Yan and Xiong, Chengjie and Morris, John C. and Karch, Celeste and Daniels, Alisha J. and McDade, Eric and Bateman, Randall J.}, doi = {10.1212/WNL.0000000000214804}, journal-iso = {NEUROLOGY}, journal = {NEUROLOGY}, volume = {106}, unique-id = {37292880}, issn = {0028-3878}, year = {2026}, eissn = {1526-632X} } @article{MTMT:37029359, title = {Impact of Age at Onset on Relapse and Disability in AQP4-IgG Neuromyelitis Optica Spectrum Disorder}, url = {https://m2.mtmt.hu/api/publication/37029359}, author = {Siriratnam, Pakeeran and Jokubaitis, Vilija G. and Van, Der Walt Anneke and Sanfilippo, Paul G. and Zhu, Chao and Etemadifar, Masoud and Altintas, Ayse and Al-Asmi, Abdullah and Laureys, Guy and Meca-Lallana, Jose E. and Foschi, Matteo and Alroughani, Raed and Gomez-Figueroa, Enrique and Habek, Mario and Khoury, Samia J. and Simó, Magdolna and Singhal, Bhim Sen G. and Jakob, Gregor Brecl and Fabis-Pedrini, Marzena J. and Soysal, Aysun and Kermode, Allan G. and Shaygannejad, Vahid and Kubala, Havrdova Eva and Millan-Pascual, Jorge and Roos, Izanne and Mccombe, Pamela Ann and Nytrova, Petra and Boz, Cavit and Surcinelli, Andrea and Kalincik, Tomas and Patti, Francesco and Huda, Saif and Butzkueven, Helmut and Monif, Mastura}, doi = {10.1212/WNL.0000000000214707}, journal-iso = {NEUROLOGY}, journal = {NEUROLOGY}, volume = {106}, unique-id = {37029359}, issn = {0028-3878}, abstract = {Background and Objectives Previous studies have reported inconsistent findings regarding the impact of age at onset on relapse risk in aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4-IgG NMOSD), although older disease onset has been linked to more rapid disability accrual. This is in contrast to multiple sclerosis, where advancing age and older onset are associated with reduced relapse activity, allowing for treatment de-escalation or discontinuation in some older patients. The aim of this study was to clarify the influence of age at onset on relapse risk as well as disability accrual in a large, international cohort of patients with NMOSD. Methods We conducted a retrospective, multicenter cohort study using the MSBase data registry to evaluate annualized relapse rates (ARRs), time to first relapse, and time to Expanded Disability Status Scale (EDSS) scores of 4 and 6. For inclusion, a diagnosis of AQP4-IgG NMOSD according to the latest iteration of the criteria and availability of the minimum data set were required. Patients were stratified as pediatric onset (<18 years of age), early onset (18-55 years inclusive) or late onset (>55 years of age). Analyses included patients on high-efficacy therapy (HET), those on low-efficacy therapy (LET), and an incident cohort with the first clinical visit within 12 months from disease onset. Predictors of first relapse and EDSS 4/6 thresholds were analyzed using Cox proportional models. Results Data from 539 patients (42 pediatric, 421 with early onset, 76 with late onset; 85.2% female) with a median age at onset of 35 years (Q1 25.10, Q3 47.60) and a disease duration of 7.42 years (Q1 3.23, Q3 13.10) were analyzed. ARR and time to first relapse were not influenced by age at disease onset. Patients on HET had fewer relapses than those on LET (p < 0.001). Older age was linked to faster disability accumulation. In addition, higher baseline EDSS scores and delayed treatment were independent predictors of future disability. Discussion Our study demonstrates that while age at onset does not affect relapse risk, older patients experience more rapid disability accrual. These findings underscore the importance of early initiation of effective preventive immunotherapy in all age groups. The primary limitations of this study pertain to its retrospective design and the sole reliance on EDSS for disability assessment.}, year = {2026}, eissn = {1526-632X}, orcid-numbers = {Simó, Magdolna/0000-0002-1652-2407} }