TY - JOUR AU - OuYang, Mingjing AU - OuYang, Jiewen AU - Dong, Yibin AU - Li, Jinwei AU - Yang, Wen TI - Lewis Acid-Catalyzed Tandem Reaction Strategy for the Synthesis of Dihydrophenalene-Fused Lactones JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM PY - 2024 SN - 0022-3263 DO - 10.1021/acs.joc.4c00314 UR - https://m2.mtmt.hu/api/publication/34802495 ID - 34802495 LA - English DB - MTMT ER - TY - JOUR AU - Li, X. AU - Yuan, X. AU - Wu, Y. AU - Guo, H. AU - Liu, Q. AU - Huang, S. TI - Synthesis of 3,4,5-Trisubstituted 1,2,4-Triazoles via I2-Catalyzed Cycloaddition of Amidines with Hydrazones JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM PY - 2024 SN - 0022-3263 DO - 10.1021/acs.joc.3c02637 UR - https://m2.mtmt.hu/api/publication/34794428 ID - 34794428 N1 - Export Date: 17 April 2024 CODEN: JOCEA Correspondence Address: Li, X.; College of Biomedical Engineering, 79 West Yingze Street, China; email: lixing@tyut.edu.cn AB - A general and practical method for the construction of various 3,4,5-trisubstituted 1,2,4-triazoles via I2-catalyzed cycloaddition of N-functionalized amidines with hydrazones is reported. This strategy features cheap and readily available catalyst and starting materials, broader substrate scope, and moderate-to-good yields. The mechanism study shows that the existence of hydrogen on the nitrogen of hydrazones is crucial for this transformation. © 2024 American Chemical Society. LA - English DB - MTMT ER - TY - JOUR AU - Yang, Qi AU - Huang, Shuntao AU - Yin, Lu AU - Wang, Zhuoyu AU - Chen, Xuebing AU - Huang, Chao TI - NBS-Promoted Synthesis of Thiocyanated Aminomaleimides and Site-Selective Intramolecular Cyclization Access to 1,4-Benzothiazepines via S–CN Bond Cleavage JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM PY - 2024 SN - 0022-3263 DO - 10.1021/acs.joc.3c02607 UR - https://m2.mtmt.hu/api/publication/34789389 ID - 34789389 LA - English DB - MTMT ER - TY - JOUR AU - Ábrányi-Balogh, Péter AU - Molnárné Samu, Erika AU - Pánczél, János K. AU - Benkő, Zoltán AU - Simig, Gyula AU - Volk, Balázs TI - Computational Studies on the Diastereospecific Lithium Variant of Oppenauer Oxidation of a Tofisopam Intermediate JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM PY - 2024 PG - 6 SN - 0022-3263 DO - 10.1021/acs.joc.3c02660 UR - https://m2.mtmt.hu/api/publication/34778896 ID - 34778896 N1 - Medicinal Chemistry Research Group, Research Centre for Natural Sciences, Magyar tudósok krt. 2, Budapest, H-1117, Hungary Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, H-1111, Hungary National Laboratory for Drug Research and Development, Magyar tudósok krt. 2, Budapest, H-1117, Hungary Directorate of Drug Substance Development, Egis Pharmaceuticals Plc., Budapest, H-1475, Hungary Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Szt. Gellért tér 4, Budapest, H-1111, Hungary Export Date: 12 April 2024 CODEN: JOCEA Correspondence Address: Ábrányi-Balogh, P.; Medicinal Chemistry Research Group, Magyar tudósok krt. 2, Hungary; email: abranyi-balogh.peter@ttk.hu Correspondence Address: Volk, B.; Directorate of Drug Substance Development, Hungary; email: volk.balazs@egis.hu LA - English DB - MTMT ER - TY - JOUR AU - Wang, Jie AU - Xiao, Jing AU - Tang, Zi-Long AU - Lan, Dong-Hui AU - Han, Li-Biao TI - Reductive Coupling of P(O)-H Compounds and Aldehydes for the General Synthesis of Phosphines and Phosphine Oxides JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM PY - 2024 PG - 9 SN - 0022-3263 DO - 10.1021/acs.joc.3c02678 UR - https://m2.mtmt.hu/api/publication/34766467 ID - 34766467 N1 - Funding Agency and Grant Number: Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang [22378107, 22277025]; National Natural Science Foundation of China [2022R01021]; Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang [E22330]; Open Project Program of Key Laboratory of Theoretical Organic Chemistry and Functional Molecule, Ministry of Education Funding text: The authors acknowledge financial support from the National Natural Science Foundation of China (22378107 and 22277025), the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang (2022R01021), and the Open Project Program of Key Laboratory of Theoretical Organic Chemistry and Functional Molecule, Ministry of Education (E22330). AB - A novel strategy for the selective construction of a C(sp(3))-P(III) or -P(V) bond from >P(O)-H compounds and aldehydes is disclosed. By using the H3PO3/I-2 system, various secondary phosphine oxides could react with both aromatic and aliphatic aldehydes to afford valuable phosphines (isolated as sulfides) and phosphine oxides in good yields. This method features a wide substrate scope and simple reaction conditions and avoids the use of toxic halides and metals. LA - English DB - MTMT ER - TY - JOUR AU - Pan, Q.-J. AU - Miao, Y.-Q. AU - Cao, H.-J. AU - Liu, Z. AU - Chen, X. TI - Visible Light-Induced 1,2-Diphenyldisulfane-Mediated Defluoroborylation of Polyfluoroarenes JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM PY - 2024 SN - 0022-3263 DO - 10.1021/acs.joc.4c00286 UR - https://m2.mtmt.hu/api/publication/34757297 ID - 34757297 N1 - Henan Key Laboratory of Boron Chemistry and Advanced Energy Materials, School of Chemistry and Chemical Engineering, Henan Normal University, Henan, Xinxiang, 453007, China College of Chemistry, Zhengzhou University, Henan, Zhengzhou, 450001, China Export Date: 26 March 2024 CODEN: JOCEA Correspondence Address: Liu, Z.; College of Chemistry, Henan, China; email: Xuenian_Chen@zzu.edu.cn Correspondence Address: Chen, X.; Henan Key Laboratory of Boron Chemistry and Advanced Energy Materials, Henan, China; email: Liuzhenxing@zzu.edu.cn AB - A green and practical protocol of defluoroborylation of polyfluoroarenes with stable and readily accessible NHC-borane was developed, using 1,2-diphenyldisulfane as a hydrogen atom transfer (HAT) and single electron transfer (SET) reagent precursor under visible-light irradiation, leading to the concise formation of value-added fluorinated organoboron scaffolds. Mechanism studies revealed the method underwent a boryl radical addition reaction with polyfluoroarene, followed by successive single electron transfer pathways and defluorination of the C-F bond to offer the targeted product. This unprecedented platform relies on 1,2-diphenyldisulfane and base without using expensive photocatalysts, highlighting the methodology has promising application value to prepare borylated polyfluoroarene compounds. © 2024 American Chemical Society. LA - English DB - MTMT ER - TY - JOUR AU - Šlachtová, V. AU - Bellová, S. AU - Vrabel, M. TI - Synthesis of C3-Substituted N1-tert-Butyl 1,2,4-Triazinium Salts via the Liebeskind-Srogl Reaction for Fluorogenic Labeling of Live Cells JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM PY - 2024 SN - 0022-3263 DO - 10.1021/acs.joc.3c02454 UR - https://m2.mtmt.hu/api/publication/34746702 ID - 34746702 N1 - Export Date: 20 March 2024 CODEN: JOCEA Correspondence Address: Vrabel, M.; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, Czech Republic; email: vrabel@uochb.cas.cz LA - English DB - MTMT ER - TY - JOUR AU - Chen, Zicong AU - Pang, Wai Hang AU - Yuen, On Ying AU - Ng, Shan Shan AU - So, Chau Ming TI - Palladium-Catalyzed Chemoselective Phosphorylation of Poly(pseudo)halides: A Route for Organophosphorus Synthesis JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM PY - 2024 SN - 0022-3263 DO - 10.1021/acs.joc.3c02345 UR - https://m2.mtmt.hu/api/publication/34715064 ID - 34715064 N1 - State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, 000000, Hong Kong The Hong Kong Polytechnic University, Shenzhen Research Institute, Shenzhen, 518000, China Export Date: 14 March 2024 CODEN: JOCEA Correspondence Address: So, C.M.; State Key Laboratory of Chemical Biology and Drug Discovery, Hung Hom, Hong Kong; email: chau.ming.so@polyu.edu.hk LA - English DB - MTMT ER - TY - JOUR AU - Alekseeva, Kseniya A. AU - Fedoseeva, Milana A. AU - Bakhanovich, Olga V. AU - Khrustalev, Victor N. AU - Potkin, Vladimir I. AU - Zhou, Hongwei AU - Nikitina, Eugenia V. AU - Zaytsev, Vladimir P. AU - Zubkov, Fedor I. TI - One-Pot Reaction Sequence: N -Acylation/Pictet–Spengler Reaction/Intramolecular [4 + 2] Cycloaddition/Aromatization in the Synthesis of β-Carboline Alkaloid Analogues JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM PY - 2024 SN - 0022-3263 DO - 10.1021/acs.joc.3c02533 UR - https://m2.mtmt.hu/api/publication/34684536 ID - 34684536 LA - English DB - MTMT ER - TY - JOUR AU - W., Lee AU - T.R., Benton AU - A., Sengupta AU - K.N., Houk TI - Molecular Dynamics of the Norbornyl Cation in Solution and Its Generation in Winstein−Trifan Solvolysis: The Timing of Sigma Bridging JF - JOURNAL OF ORGANIC CHEMISTRY J2 - J ORG CHEM VL - 89 PY - 2024 SP - 1140 EP - 1146 PG - 7 SN - 0022-3263 UR - https://m2.mtmt.hu/api/publication/34524713 ID - 34524713 LA - English DB - MTMT ER -