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Division of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States
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<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34716168" target="_blank">Comparative Safety and Effectiveness of Warfarin or Rivaroxaban Versus Apixaban in Patients With Advanced CKD and Atrial Fibrillation: Nationwide US Cohort Study</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF KIDNEY DISEASES</span>
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<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States
Division of Renal Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States
New England Geriatric Research Education and Clinical Ce...</pre>
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J. Philip Kistler Stroke Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States
Global Brain Health Institute, Trinity College Dublin, Ireland
Export Date: 18 January 2024
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<div class="lastModified">Utolsó módosítás: 2024.03.09. 17:08 Házkötő Béláné (SE_AOK_3Bel_Admin5_Hani, admin)
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<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: The George Institute for Global Health, Sydney, NSW, Australia
Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia
Department of Renal Medicine, St George Hospital, Sydney, NSW, Australia
Heart Research Institute, Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia ...</pre>
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<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34512939" target="_blank">KDOQI Commentary on the KDIGO 2022 Update to the Clinical Practice Guideline for Diabetes Management in CKD</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF KIDNEY DISEASES</span>
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<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Export Date: 18 January 2024
CODEN: AJKDD
Correspondence Address: Mottl, A.K.; University of North Carolina Kidney Center, CB# 7155, United States; email: amy_mottl@med.unc.edu</pre>
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<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Division of Nephrology, Department of Medicine, University of Illinois Chicago, Chicago, Illinois, United States
Section of Nephrology, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States
Hamburg Center for Kidney Health, University Medical Center Hamburg, Hamburg, Germany ...</pre>
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Ebert, Thomas </span> <span class="author-type"> </span> ; <span class="author-name" > Sattar, Nosheen </span> <span class="author-type"> </span> ; <span class="author-name" > Greig, Marni </span> <span class="author-type"> </span> ; <span class="author-name" > Lamina, Claudia </span> <span class="author-type"> </span> ; <span class="author-name" > Froissart, Marc </span> <span class="author-type"> </span> ; <span class="author-name" > Eckardt, Kai -Uwe </span> <span class="author-type"> </span> ; <span class="author-name" > Floege, Jorgen </span> <span class="author-type"> </span> ; <span class="author-name" > Kronenberg, Florian </span> <span class="author-type"> </span> ; <span class="author-name" > Stenvinkel, Peter </span> <span class="author-type"> </span> ; <span class="author-name" > Wheeler, David C. </span> <span class="author-type"> </span> et al. </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34626917" mtid="34626917" target="_blank">Use of Analog and Human Insulin in a European Hemodialysis Cohort With Type 2 Diabetes: Associations With Mortality, Hospitalization, MACE, and Hypoglycemia</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF KIDNEY DISEASES</span> <span class="journal-volume">83</span> : <span class="journal-issue">1</span> <span class="page"> pp. 18-27. , 10 p. </span> <span class="year">(2024)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="10.1053/j.ajkd.2023.05.010" target="_blank" href="https://doi.org/10.1053/j.ajkd.2023.05.010"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001141053300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001141053300001"> WoS </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34626917 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
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Rationale & Objective: Optimal approaches treat secondary hyperparathyroidism (SHPT) patients on maintenance hemodialysis (HD) have yet to be established in randomized controlled trials (RCTs). Study Design: Two observational clinical trial emulations. Setting & Participants: Both emulations included adults receiving in-center HD from a national dialysis organization. The patients who had SHPT in the period between 2009 and 2014, were insured for >_180 days by Medicare as primary payer, and did not have contraindications or poor health status limiting theoretical trial participation.Exposure: The parathyroid hormone (PTH) Target Trial emulation included patients with new-onset SHPT (first PTH 300-600 pg/mL), with 2 arms defined as up-titration of either vitamin D sterols or cinacalcet within 30 days (lower target) or up-titration (higher target). The Agent Trial emulation included patients with a PTH >_300 pg/mL while on >_6 mu g weekly of vitamin D sterol (paricalcitol equivalent dose) and no prior history of cinacalcet. The 2 arms were defined by the first dose or agent change within 30 days (vitamin D-favoring [vitamin-D was up-titrated] cinacalcet-favoring [cinacalcet was added] nondefined [neither applies]). Multiple trials patient were allowed in trial 2.Outcome: The primary outcome was all-cause death over 24 months; secondary outcomes included cardiovascular (CV) hospitalization or the composite of CV hospitalization or death. Analytical Approach: Pooled logistic regression. Results: There were 1,152 patients in the PTH Target Trial (635 lower target and 517 higher target). There were 2,726 unique patients with 6,727 patient trials in the Agent Trial (6,268 vitamin D-favoring trials and 459 cinacalcetfavoring trials). The lower PTH target approach was associated with reduced adjusted hazard of death (HR, 0.71 [95% CI, 0.52-0.93]), CV hospitalization (HR, 0.78 [95% CI, 0.63-0.9 8]), and their composite (HR, 0.74 [95% CI, 0.61-0.8 9]). The cinacalcet-favoring approach demonstrated lower adjusted hazard of death compared to the vitamin D-favoring approach (HR, 0.79 [95% CI, 0.62-0.9 9]), but not of CV hospitalization or the composite outcome. Limitations: Potential for residual confounding; low use of cinacalcet with low power. Conclusions: SHPT management that is focused on lower PTH targets may lower mortality and CV disease in patients receiving HD. These findings should be confirmed in a pragmatic randomized trial.
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Platt, Alyssa </span> <span class="author-type"> </span> ; <span class="author-name" > Wilson, Jonathan </span> <span class="author-type"> </span> ; <span class="author-name" > Hall, Rasheeda </span> <span class="author-type"> </span> ; <span class="author-name" > Ephraim, Patti L. </span> <span class="author-type"> </span> ; <span class="author-name" > Morton, Sarah </span> <span class="author-type"> </span> ; <span class="author-name" > Shafi, Tariq </span> <span class="author-type"> </span> ; <span class="author-name" > Weiner, Daniel E. </span> <span class="author-type"> </span> ; <span class="author-name" > Boulware, L. Ebony </span> <span class="author-type"> </span> ; <span class="author-name" > Pendergast, Jane </span> <span class="author-type"> </span> ; <span class="author-name" > Scialla, Julia J. ✉ </span> <span class="author-type"> </span> et al. </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34612137" mtid="34612137" target="_blank">Comparative Effectiveness of Alternative Treatment Approaches to Secondary Hyperparathyroidism in Patients Receiving Maintenance Hemodialysis: An Observational Trial Emulation</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF KIDNEY DISEASES</span> <span class="journal-volume">83</span> : <span class="journal-issue">1</span> <span class="page"> pp. 58-70. , 13 p. </span> <span class="year">(2024)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001141037900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001141037900001"> WoS </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34612137 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
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<div class="autype autype0"> <span class="author-name" >Platt Alyssa
</span>
;
<span class="author-name" >Wilson Jonathan
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<span class="author-name" >Pendergast Jane
</span>
;
<span class="author-name" >Scialla Julia J. ✉
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<div class="autype autype-29"> Kollaborációs szervezet:
<span class="author-affil">Comparative Effectiveness Studies</span>
</div>
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<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34612137" target="_blank">Comparative Effectiveness of Alternative Treatment Approaches to Secondary Hyperparathyroidism in Patients Receiving Maintenance Hemodialysis: An Observational Trial Emulation</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF KIDNEY DISEASES</span>
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Kearney, Andrew O. </span> <span class="author-type"> </span> ; <span class="author-name" > Lerma, Edgar </span> <span class="author-type"> </span> ; <span class="author-name" > Lin, Jennie ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34600511" mtid="34600511" target="_blank">Building Toward Clinical Translation: New Study Refines Genetic Architecture of IgA Nephropathy</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF KIDNEY DISEASES</span> <span class="journal-volume">83</span> : <span class="journal-issue">1</span> <span class="page"> pp. 108-111. , 4 p. </span> <span class="year">(2024)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1053/j.ajkd.2023.09.001" target="_blank" href="https://doi.org/10.1053/j.ajkd.2023.09.001"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001141146100001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001141146100001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85174745625" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85174745625"> Scopus </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34600511 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Ismertetés ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
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<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34600511" target="_blank">Building Toward Clinical Translation: New Study Refines Genetic Architecture of IgA Nephropathy</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF KIDNEY DISEASES</span>
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<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Export Date: 28 February 2024; CODEN: AJKDD</pre>
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Division of Nephrology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States
Division of Nephrology-Hypertension, University of California–San Diego, San Diego, California, United States
Veterans Affairs San Diego Healthcare System, San Diego, CA, United States
Kidney Health Research Collaborative, Department of Medicine, University of California–San Francisco, San Francisco, California, United States
Renal Division, Brigham & Women's Hospital, Boston, Massachusetts, United States
Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States
Section of Nephrology and Clinical and Translational Research Accelerator, Department of Internal Medicine, School of Medicine, Yale University, New Haven, Connecticut, United States
Renal Section, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, United States
Export Date: 6 November 2023
CODEN: AJKDD
Correspondence Address: Parikh, C.R.; Johns Hopkins University School of Medicine, 1830 E Monument St, Ste 416, United States; email: chirag.parikh@jhmi.edu
Funding details: National Institutes of Health, NIH, K23DK117065, P30DK079310, R01DK093770, R01DK128087, R01HL085757, U01DK106962, U01DK114866, U01DK129984
Funding details: National Institute of Diabetes and Digestive and Kidney Diseases, NIDDK, R37DK39773, RO1DK072381, U01DK085660, U01DK102730
Funding details: Boehringer Ingelheim, BI
Funding details: Office of Research and Development, ORD
Funding details: Johns Hopkins University, JHU
Funding text 1: Elizabeth A. Kiernan, MD, David Hu, MS, Heather Thiessen Philbrook, MMath, Joachim H. Ix, MD, MAS, Joseph V. Bonventre, MD, PhD, Steven G. Coca, DO, MS, Dennis G. Moledina, MD, PhD, Linda F. Fried, MD, MPH, Michael G. Shlipak, MD, MPH, and Chirag R. Parikh, MD, PhD. Research idea and study design: EK, HTP, SGC, CRP; data acquisition: CRP, LFF; data analysis/interpretation: DH, HTP, CRP; statistical analysis: DH, HTP; biomarker measurements: CRP, JVB; supervision or mentorship: JI, SGC, DGM, LFF, MGS, CRP. Each author contributed important intellectual content during manuscript drafting or revision and agrees to be personally accountable for the individual's own contributions and to ensure that questions pertaining to the accuracy or integrity of any portion of the work, even one in which the author was not directly involved, are appropriately investigated and resolved, including with documentation in the literature if appropriate. Dr Parikh is supported by NIH grants R01HL085757, U01DK114866, U01DK106962, U01DK129984, and R01DK093770, and P30DK079310. Dr Moledina is supported by K23DK117065 and R01DK128087. Drs Ix and Shlipak are supported by NIH/NIDDK U01DK102730. Dr Bonventre is supported by U01DK085660, RO1DK072381, and R37DK39773. The funders of this study had no role in current study design, collection, analysis or interpretation of the data, writing of the report, or decision to submit the report for publication. Drs Coca and Parikh are members of the advisory board of Renalytix and own equity in the same. Dr Parikh serves as a consultant for Genfit. Dr Coca has received consulting fees from Renalytix, Nuwellis, Takeda Pharmaceuticals, Vifor, 3ive, Reprieve Cardiovascular, Axon Therapies, Bayer, and Boehringer-Ingelheim. Drs Moledina and Parikh are co-inventors of the pending patent application “Methods and Systems for Diagnosis of Acute Interstitial Nephritis.” Dr Bonventre is cofounder and holds equity in Goldfinch Bio and Autonomous Medical Devices; is co-inventor on KIM-1 patents assigned to MassGeneralBrigham; has received consulting income and/or equity from Aldeyra, AstraZenica, Biomarin, Cadent, Citrine, DxNow, Goldilocks, MediBeacon, PTC, Praxis, Renalytix, Sarepta, and Seagen, and laboratory support from Kantum Pharma; has equity in Pacific Biosciences; and his interests are reviewed and managed by BWH and MGB in accordance with their conflict-of-interest policies. The other authors declare that they have no relevant financial interests. CSP# 565 Combination Angiotensin Receptor Blocker and Angiotensin Converting Enzyme Inhibitor for Treatment of Diabetic Nephropathy (VA NEPHRON-D) was conducted and supported by the Department of Veterans Affairs Cooperative Studies Program (VACSP), Office of Research and Development. We thank the participants of the VA NEPHRON-D trial. The content of this manuscript is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. This analysis was carried out by the listed authors utilizing data that was specified and obtained under the Data Use Agreement (DUA) between VACSP and Johns Hopkins University, dated 01/09/2019. All statements, opinions, or views are solely of the author(s) and do not reflect official views of VA. Received October 13, 2022. Evaluated by 2 external peer reviewers, with direct editorial input from 2 Statistics/Methods Editors, an Associate Editor, and a Deputy Editor who served as Acting Editor-in-Chief. Accepted in revised form July 2, 2023. The involvement of an Acting Editor-in-Chief was to comply with AJKD's procedures for potential conflicts of interest for editors, described in the Information for Authors & Journal Policies.
Funding text 2: Dr Parikh is supported by NIH grants R01HL085757, U01DK114866, U01DK106962, U01DK129984, and R01DK093770, and P30DK079310. Dr Moledina is supported by K23DK117065 and R01DK128087. Drs Ix and Shlipak are supported by NIH/NIDDK U01DK102730. Dr Bonventre is supported by U01DK085660, RO1DK072381, and R37DK39773. The funders of this study had no role in current study design, collection, analysis or interpretation of the data, writing of the report, or decision to submit the report for publication.
Funding text 3: CSP# 565 Combination Angiotensin Receptor Blocker and Angiotensin Converting Enzyme Inhibitor for Treatment of Diabetic Nephropathy (VA NEPHRON-D) was conducted and supported by the Department of Veterans Affairs Cooperative Studies Program (VACSP), Office of Research and Development. We thank the participants of the VA NEPHRON-D trial.
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Rationale & Objective: Urinary biomarkers of injury, inflammation, and repair may help phenotype acute kidney injury (AKI) observed in clinical trials. We evaluated the differences in biomarkers between participants randomized to monotherapy or to combination renin-angiotensin-aldosterone system (RAAS) blockade in VA NEPHRON-D, where an increased proportion of observed AKI was acknowledged in the combination arm. Study Design: Longitudinal analysis. Setting & Participants: A substudy of the VA NEPHRON-D trial. Predictor: Primary exposure was the treatment arm (combination [RAAS inhibitor] vs monotherapy). AKI is used as a stratifying variable. Outcome: Urinary biomarkers, including albumin, EGF (epidermal growth factor), MCP-1 (monocyte chemoattractant protein-1), YKL-40 (chitinase 3-like protein 1), and KIM-1 (kidney injury molecule-1). Analytical Approach: Biomarkers measured at baseline and at 12 months in trial participants were compared between treatment groups and by AKI. AKI events occurring during hospitalization were predefined safety end points in the original trial. The results were included in a meta-analysis with other large chronic kidney disease trials to assess global trends in biomarker changes. Results: In 707 participants followed for a median of 2.2 years, AKI incidence was higher in the combination (20.7%) versus the monotherapy group (12.7%; relative risk [RR], 1.64 [95% CI, 1.16-2.30]). Compared with the monotherapy arm, in the combination arm the urine biomarkers at 12 months were either unchanged (MCP-1: RR, −3% [95% CI, −13% to 9%], Padj = 0.8; KIM-1: RR, −10% [95% CI, −20% to 1%], Padj = 0.2; EGF, RR −7% [95% CI, −12% to −1%], Padj = 0.08) or lower (albuminuria: RR, −24% [95% CI, −37% to −8%], Padj = 0.02; YKL: RR, −40% to −44% [95% CI, −58% to −25%], Padj < 0.001). Pooled meta-analysis demonstrated reduced albuminuria in the intervention arm across 3 trials and similar trajectories in other biomarkers. Limitations: Biomarker measurement was limited to 2 time points independent of AKI events. Conclusions: Despite the increased risk of serum creatinine–defined AKI, combination RAAS inhibitor therapy was associated with unchanged or decreased urinary biomarkers at 12 months. This suggests a possible role for kidney biomarkers to further characterize kidney injury in clinical trials. Plain-Language Summary: The VA NEPHRON-D trial investigated inhibition of the renin-angiotensin-aldosterone system (RAAS) hormonal axis on kidney outcomes in a large population of diabetic chronic kidney disease patients. The trial was stopped early due to increased events of serum creatinine–defined acute kidney injury in the combination therapy arm. Urine biomarkers can serve as an adjunct to serum creatinine in identifying kidney injury. We found that urinary biomarkers in the combination therapy group were not associated with a pattern of harm and damage to the kidney, despite the increased number of kidney injury events in that group. This suggests that serum creatinine alone may be insufficient for defining kidney injury and supports further exploration of how other biomarkers might improve identification of kidney injury in clinical trials. © 2023 The Authors
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Kiernan, E.A. </span> <span class="author-type"> </span> ; <span class="author-name" > Hu, D. </span> <span class="author-type"> </span> ; <span class="author-name" > Philbrook, H.T. </span> <span class="author-type"> </span> ; <span class="author-name" > Ix, J.H. </span> <span class="author-type"> </span> ; <span class="author-name" > Bonventre, J.V. </span> <span class="author-type"> </span> ; <span class="author-name" > Coca, S.G. </span> <span class="author-type"> </span> ; <span class="author-name" > Moledina, D.G. </span> <span class="author-type"> </span> ; <span class="author-name" > Fried, L.F. </span> <span class="author-type"> </span> ; <span class="author-name" > Shlipak, M.G. </span> <span class="author-type"> </span> ; <span class="author-name" > Parikh, C.R. ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34259416" mtid="34259416" target="_blank">Urinary Biomarkers and Kidney Injury in VA NEPHRON-D: Phenotyping Acute Kidney Injury in Clinical Trials</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF KIDNEY DISEASES</span> <span class="journal-volume"></span> <span class="page"> </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1053/j.ajkd.2023.07.012" target="_blank" href="https://doi.org/10.1053/j.ajkd.2023.07.012"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85174839480" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85174839480"> Scopus </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34259416 </span> <span class="status-holder"><span class="status-data status-APPROVED"> Nyilvános </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
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<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34259416" target="_blank">Urinary Biomarkers and Kidney Injury in VA NEPHRON-D: Phenotyping Acute Kidney Injury in Clinical Trials</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF KIDNEY DISEASES</span>
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<div class="lastModified">Utolsó módosítás: 2023.11.06. 17:05 Sonnevend Kinga (SE_AOK_Adm5_Élet_kutcsop, admin)
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<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Division of Nephrology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States
Division of Nephrology-Hypertension, University of California–San Diego, San Diego, California, United States
Veterans Affairs San Diego Healthcare System, San Diego, CA, United States
Kidney Heal...</pre>
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