@article{MTMT:34663792,
	title = {The trajectory of very old critically ill patients},
	url = {https://m2.mtmt.hu/api/publication/34663792},
	author = {Guidet, Bertrand and Vallet, Helene and Flaatten, Hans and Joynt, Gavin and Bagshaw, Sean M. and Leaver, Susannah K. and Beil, Michael and Du, Bin and Forte, Daniel N. and Angus, Derek C. and Sviri, Sigal and de Lange, Dylan and Herridge, Margaret S. and Jung, Christian},
	doi = {10.1007/s00134-023-07298-z},
	journal-iso = {INTENS CARE MED},
	journal = {INTENSIVE CARE MEDICINE},
	unique-id = {34663792},
	issn = {0342-4642},
	keywords = {intensive care unit; Critical care; Trajectory; decision-making process; old patients},
	year = {2024},
	eissn = {1432-1238}
}

@article{MTMT:34660292,
	title = {The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations},
	url = {https://m2.mtmt.hu/api/publication/34660292},
	author = {Turella, Sara and Dankiewicz, Josef and Friberg, Hans and Jakobsen, Janus Christian and Leithner, Christoph and Levin, Helena and Lilja, Gisela and Moseby-Knappe, Marion and Nielsen, Niklas and Rossetti, Andrea O. and Sandroni, Claudio and Zubler, Frederic and Cronberg, Tobias and Westhall, Erik},
	doi = {10.1007/s00134-023-07280-9},
	journal-iso = {INTENS CARE MED},
	journal = {INTENSIVE CARE MEDICINE},
	unique-id = {34660292},
	issn = {0342-4642},
	keywords = {Prognosis; EEG; outcome; brain injury; Coma; Cardiac arrest},
	year = {2024},
	eissn = {1432-1238},
	orcid-numbers = {Jakobsen, Janus Christian/0000-0002-3642-2120}
}

@article{MTMT:34640248,
	title = {Clinical practice and effect of carbon dioxide on outcomes in mechanically ventilated acute brain-injured patients: a secondary analysis of the ENIO study},
	url = {https://m2.mtmt.hu/api/publication/34640248},
	author = {Robba, Chiara and Battaglini, Denise and Abbas, Abbas and Sarrio, Ezequiel and Cinotti, Raphael and Asehnoune, Karim and Taccone, Fabio S. and Rocco, Patricia R. and Schultz, Marcus J. and Citerio, Giuseppe and Stevens, Robert David and Badenes, Rafael},
	doi = {10.1007/s00134-023-07305-3},
	journal-iso = {INTENS CARE MED},
	journal = {INTENSIVE CARE MEDICINE},
	unique-id = {34640248},
	issn = {0342-4642},
	keywords = {Carbon Dioxide; intensive care; stroke; brain injury; hyperventilation; Critical care; TBI; ICH; SAH; PaCO2; INVASIVE VENTILATION},
	year = {2024},
	eissn = {1432-1238}
}

@article{MTMT:34604223,
	title = {ICU-acquired infections in immunocompromised patients},
	url = {https://m2.mtmt.hu/api/publication/34604223},
	author = {Kreitmann, Louis and Helms, Julie and Martin-Loeches, Ignacio and Salluh, Jorge and Poulakou, Garyphallia and Pene, Frederic and Nseir, Saad},
	doi = {10.1007/s00134-023-07295-2},
	journal-iso = {INTENS CARE MED},
	journal = {INTENSIVE CARE MEDICINE},
	unique-id = {34604223},
	issn = {0342-4642},
	abstract = {Immunocompromised patients account for an increasing proportion of the typical intensive care unit (ICU) case-mix. Because of the increased availability of new drugs for cancer and auto-immune diseases, and improvement in the care of the most severely immunocompromised ICU patients (including those with hematologic malignancies), critically ill immunocompromised patients form a highly heterogeneous patient population. Furthermore, a large number of ICU patients with no apparent immunosuppression also harbor underlying conditions altering their immune response, or develop ICU-acquired immune deficiencies as a result of sepsis, trauma or major surgery. While infections are associated with significant morbidity and mortality in immunocompromised critically ill patients, little specific data are available on the incidence, microbiology, management and outcomes of ICU-acquired infections in this population. As a result, immunocompromised patients are usually excluded from trials and guidelines on the management of ICU-acquired infections. The most common ICU-acquired infections in immunocompromised patients are ventilator-associated lower respiratory tract infections (which include ventilator-associated pneumonia and tracheobronchitis) and bloodstream infections. Recently, several large observational studies have shed light on some of the epidemiological specificities of these infections-as well as on the dynamics of colonization and infection with multidrug-resistant bacteria-in these patients, and these will be discussed in this review. Immunocompromised patients are also at higher risk than non-immunocompromised hosts of fungal and viral infections, and the diagnostic and therapeutic management of these infections will be covered. Finally, we will suggest some important areas of future investigation.},
	keywords = {critical illness; VENTILATOR-ASSOCIATED PNEUMONIA; intensive care units; ANTIMICROBIAL RESISTANCE; bloodstream infection; Immunocompromised patients; Cross-infection},
	year = {2024},
	eissn = {1432-1238}
}

@article{MTMT:34509518,
	title = {Contemporary management of major haemorrhage in critical care},
	url = {https://m2.mtmt.hu/api/publication/34509518},
	author = {Maier, C.L. and Brohi, K. and Curry, N. and Juffermans, N.P. and Miquel, L.M. and Neal, M.D. and Shaz, B.H. and Vlaar, A.P.J. and Helms, J.},
	doi = {10.1007/s00134-023-07303-5},
	journal-iso = {INTENS CARE MED},
	journal = {INTENSIVE CARE MEDICINE},
	volume = {In press},
	unique-id = {34509518},
	issn = {0342-4642},
	year = {2024},
	eissn = {1432-1238},
	pages = {In press}
}

@article{MTMT:34775604,
	title = {Intensive care admission aiming at organ donation. Pro},
	url = {https://m2.mtmt.hu/api/publication/34775604},
	author = {Pérez-Blanco, A. and Manara, A.},
	doi = {10.1007/s00134-024-07334-6},
	journal-iso = {INTENS CARE MED},
	journal = {INTENSIVE CARE MEDICINE},
	volume = {50},
	unique-id = {34775604},
	issn = {0342-4642},
	year = {2024},
	eissn = {1432-1238},
	pages = {437-439}
}

@article{MTMT:34649761,
	title = {Acute kidney disease beyond day 7 after major surgery: a secondary analysis of the EPIS-AKI trial},
	url = {https://m2.mtmt.hu/api/publication/34649761},
	author = {Meersch, Melanie and Weiss, Raphael and Strauss, Christian and Albert, Felix and Booke, Hendrik and Forni, Lui and Pittet, Jean-Francois and Kellum, John A. and Rosner, Mitchell and Mehta, Ravindra and Bellomo, Rinaldo and Rosenberger, Peter and Zarbock, Alexander},
	doi = {10.1007/s00134-023-07314-2},
	journal-iso = {INTENS CARE MED},
	journal = {INTENSIVE CARE MEDICINE},
	volume = {50},
	unique-id = {34649761},
	issn = {0342-4642},
	keywords = {surgery; chronic kidney disease; acute kidney injury; postoperative; Acute kidney disease},
	year = {2024},
	eissn = {1432-1238},
	pages = {247-257}
}

@article{MTMT:34492974,
	title = {Diagnosis and management of autoimmune diseases in the ICU},
	url = {https://m2.mtmt.hu/api/publication/34492974},
	author = {Dumas, G. and Arabi, Y.M. and Bartz, R. and Ranzani, O. and Scheibe, F. and Darmon, M. and Helms, J.},
	doi = {10.1007/s00134-023-07266-7},
	journal-iso = {INTENS CARE MED},
	journal = {INTENSIVE CARE MEDICINE},
	volume = {50},
	unique-id = {34492974},
	issn = {0342-4642},
	year = {2024},
	eissn = {1432-1238},
	pages = {17-35}
}

@article{MTMT:34637539,
	title = {Status epilepticus in the ICU},
	url = {https://m2.mtmt.hu/api/publication/34637539},
	author = {Rossetti, Andrea O. and Claassen, Jan and Gaspard, Nicolas},
	doi = {10.1007/s00134-023-07263-w},
	journal-iso = {INTENS CARE MED},
	journal = {INTENSIVE CARE MEDICINE},
	unique-id = {34637539},
	issn = {0342-4642},
	keywords = {MORTALITY; treatment; outcome; STATUS EPILEPTICUS; Second-line},
	year = {2023},
	eissn = {1432-1238},
	orcid-numbers = {Gaspard, Nicolas/0000-0003-1148-6723}
}

@article{MTMT:34362267,
	title = {Differences in directives to limit treatment and discontinue mechanical ventilation between elderly and very elderly patients: a substudy of a multinational observational study},
	url = {https://m2.mtmt.hu/api/publication/34362267},
	author = {Burns, Karen E. A. and Cook, Deborah J. and Xu, Keying and Dodek, Peter and Villar, Jesus and Jones, Andrew and Kapadia, Farhad N. and Gattas, David J. and Epstein, Scott K. and Pelosi, Paolo and Kefala, Kallirroi and Meade, Maureen O. and Rizvi, Leena and Canadian Critical Care Trials Grp, .},
	doi = {10.1007/s00134-023-07188-4},
	journal-iso = {INTENS CARE MED},
	journal = {INTENSIVE CARE MEDICINE},
	unique-id = {34362267},
	issn = {0342-4642},
	abstract = {Purpose: The aim of this study was to characterize differences in directives to limit treatments and discontinue invasive mechanical ventilation (IMV) in elderly (65-80 years) and very elderly (> 80 years) intensive care unit (ICU) patients.Methods: We prospectively described new written orders to limit treatments, IMV discontinuation strategies [direct extubation, direct tracheostomy, spontaneous breathing trial (SBT), noninvasive ventilation (NIV) use], and associations between initial failed SBT and outcomes in 142 ICUs from 6 regions (Canada, India, United Kingdom, Europe, Australia/New Zealand, United States).Results: We evaluated 788 (586 elderly; 202 very elderly) patients. Very elderly (vs. elderly) patients had similar withdrawal orders but significantly more withholding orders, especially cardiopulmonary resuscitation and dialysis, after ICU admission [67 (33.2%) vs. 128 (21.9%); p = 0.002]. Orders to withhold reintubation were written sooner in very elderly (vs. elderly) patients [4 (2-8) vs. 7 (4-13) days, p = 0.02]. Very elderly and elderly patients had similar rates of direct extubation [39 (19.3%) vs. 113 (19.3%)], direct tracheostomy [10 (5%) vs. 40 (6.8%)], initial SBT [105 (52%) vs. 302 (51.5%)] and initial successful SBT [84 (80%) vs. 245 (81.1%)]. Very elderly patients experienced similar ICU outcomes (mortality, length of stay, duration of ventilation) but higher hospital mortality [26 (12.9%) vs. 38 (6.5%)]. Direct tracheostomy and initial failed SBT were associated with worse outcomes. Regional differences existed in withholding orders at ICU admission and in withholding and withdrawal orders after ICU admission.Conclusions: Very elderly (vs. elderly) patients had more orders to withhold treatments after ICU admission and higher hospital mortality, but similar ICU outcomes and IMV discontinuation. Significant regional differences existed in withholding and withdrawal practices.},
	keywords = {weaning; elderly; Goals of care; Treatment limitations},
	year = {2023},
	eissn = {1432-1238}
}