@article{MTMT:34651792, title = {Biorefinery of flavonoid aglycones using acidic natural deep eutectic solvents: Role of Bronsted acids and application in valorization of Sophora japonica buds waste}, url = {https://m2.mtmt.hu/api/publication/34651792}, author = {Ni, Yishu and Zhu, Lin and Ye, Shuhui and Xu, Xiafeng and Liang, Xianrui and Fang, Sheng}, doi = {10.1016/j.fbp.2023.11.003}, journal-iso = {FOOD BIOPROD PROCESS}, journal = {FOOD AND BIOPRODUCTS PROCESSING}, volume = {143}, unique-id = {34651792}, issn = {0960-3085}, keywords = {Quercetin; deglycosylation; Deep eutectic solvent; Bronsted acid; Sophora japonica}, year = {2024}, eissn = {1744-3571}, pages = {80-89} } @article{MTMT:34619680, title = {Stochastic techno-economic analysis for the co-production of alternative sweeteners in sugarcane biorefineries}, url = {https://m2.mtmt.hu/api/publication/34619680}, author = {Amanful, Bright and Dogbe, Eunice Sefakor and Bosman, Catharine Elizabeth and Gorgens, Johann Ferdinand}, doi = {10.1016/j.fbp.2023.10.006}, journal-iso = {FOOD BIOPROD PROCESS}, journal = {FOOD AND BIOPRODUCTS PROCESSING}, volume = {143}, unique-id = {34619680}, issn = {0960-3085}, abstract = {The global sugar industry is stagnating due to oversupply of international markets, which requires investments in product diversification. Health concerns have also been raising questions about sugar as a sweetener. This study investigated the viability of producing alternative, low-calorie sweeteners in a sugarcane-mill-annexed bio-refinery, utilising A-molasses as feedstock. Single-product and multiproduct biorefineries were simulated in Aspen Plus (R) to produce isomaltulose, allulose, short-chain fructooligosaccharides (scFOS) and/or thaumatin. The minimum selling prices of isomaltulose (870 $/ton), allulose (2030 $/ton) and scFOS (1540 $/ton) in the single-product biorefineries were lower than current market prices, while that of thaumatin (11 665 000 $/ton) was higher. However, single-product biorefineries would oversupply the market. In multiproduct scenarios the available A-molasses was shared between isomaltulose, allulose and scFOS in one biorefinery, to produce <= 15% of the global market for each, using either six bioreactors operated continuously, or one bioreactor shared be-tween six process steps through scheduling. The shared-one-bioreactor had a higher deterministic IRR (60%) than the six-bioreactor scenario (50%). Stochastic financial analysis confirmed the higher IRR for the shared-one-bioreactor (41.39%) compared to the six-bioreactor (36.07%) scenario, reflecting price variabilities' impact on biorefinery profitability. Multiproduct scenarios were deemed economically attractive for A-molasses diversion from a typical sugarcane mill.}, keywords = {Biorefinery; thaumatin; SHORT-CHAIN FRUCTOOLIGOSACCHARIDES; isomaltulose; Allulose; Stochastic techno-economic analysis}, year = {2024}, eissn = {1744-3571}, pages = {9-20}, orcid-numbers = {Bosman, Catharine Elizabeth/0000-0002-5369-2739} } @article{MTMT:34561855, title = {Integrated, multi-scale and multi-objective design of batch food processing plants. Part 2: Application to a mobile fruit and vegetable processing unit}, url = {https://m2.mtmt.hu/api/publication/34561855}, author = {Savoure, Timoty and Madoumier, Martial and Rivier, Michel and Dornier, Manuel and Collignan, Antoine}, doi = {10.1016/j.fbp.2024.01.004}, journal-iso = {FOOD BIOPROD PROCESS}, journal = {FOOD AND BIOPRODUCTS PROCESSING}, volume = {144}, unique-id = {34561855}, issn = {0960-3085}, abstract = {The design of food processing plants that are plug-and-play, reconfigurable, modular, mobile and containerised is a complex task. The "Methodology for the integrated, multi-scale and multi-objective design of systems" can be used to design such systems. This was developed and the various tasks that make it up presented in a previous article by Savoure et al. (2023) (references to be specified). The aim of this study is to assess the potential of this methodology to design a mobile fruit and vegetable processing unit. Firstly, a design support tool was developed to (i) simulate the behaviour and estimate the performances of design solutions, (ii) convert their performances into desirability indices using the decision maker's preferences and (iii) search for the design solution(s) that best satisfy the decision maker's design objectives. The results were then visualised and analysed to ensure that the resulting design solution was a satisfying, feasible and coherent trade-off. This analysis also helped to understand (i) which design variables, models and assumptions drove the design decision the most and (ii) which final products, design objectives, performance indicators and preference models influenced the optimisation process the most. In particular, it showed that one of the products (okra puree) limited the performance of the design solution. Finally, this work increased the level of understanding of the design problem and challenged the preferences of the decision maker.}, keywords = {Discrete event simulation; Multi-objective optimisation; Multi-scale modeling; integrated design; Mobile Processing Plant; Multiproduct batch plant}, year = {2024}, eissn = {1744-3571}, pages = {61-74} } @article{MTMT:34329004, title = {Plant protein hydrogel as a delivery system of curcumin: Characterization and in vitro release Kinetics}, url = {https://m2.mtmt.hu/api/publication/34329004}, author = {Gupta, Sakshi and Ghoshal, Gargi}, doi = {10.1016/j.fbp.2023.10.007}, journal-iso = {FOOD BIOPROD PROCESS}, journal = {FOOD AND BIOPRODUCTS PROCESSING}, volume = {143}, unique-id = {34329004}, issn = {0960-3085}, year = {2024}, eissn = {1744-3571}, pages = {66-79} } @article{MTMT:34231428, title = {Efficacy of one-step-ultrasonic route to producing hydroxyapatite nanoparticles from cockle shells}, url = {https://m2.mtmt.hu/api/publication/34231428}, author = {Hasan, MR and Abdullah, CAC and Mustapha, NA and Ghazali, MSM and Adzahan, NM}, doi = {10.1016/j.fbp.2023.10.008}, journal-iso = {FOOD BIOPROD PROCESS}, journal = {FOOD AND BIOPRODUCTS PROCESSING}, volume = {143}, unique-id = {34231428}, issn = {0960-3085}, year = {2024}, eissn = {1744-3571}, pages = {54-65}, orcid-numbers = {Hasan, MR/0000-0002-2549-8402; Mustapha, NA/0000-0002-0891-9738} } @article{MTMT:34586457, title = {Phenolic, tocopherol, and essential fatty acid-rich extracts from dandelion seeds: Chemical composition and biological activity}, url = {https://m2.mtmt.hu/api/publication/34586457}, author = {Milovanovic, Stoja and Grzegorczyk, Agnieszka and Swiatek, Lukasz and Boguszewska, Anastazja and Kowalski, Rafal and Tyskiewicz, Katarzyna and Konkol, Marcin}, doi = {10.1016/j.fbp.2023.09.005}, journal-iso = {FOOD BIOPROD PROCESS}, journal = {FOOD AND BIOPRODUCTS PROCESSING}, volume = {142}, unique-id = {34586457}, issn = {0960-3085}, abstract = {Dandelion is a sustainable biomass that has occasional use in the food and pharmaceutical industry. However, commercial use of its extracts is restricted by the lack of systematic information on safety, composition, and biological activity. To broaden dandelion use, the present study brings new knowledge on extracts from dandelion seeds that could find application as safe and functional food ingredients. The employed two-step supercritical fluid extraction process, followed by the conventional extraction, enabled the separation of ex-tracts with increased content of phenolics, tocopherols, and essential fatty acids. Those compounds were found to be the major components of dandelion extracts, reaching high values up to 799 mg GE/g, 249 mg alpha-TE/g, and 75%, respectively. The extracts also contained significant amounts of flavonoids (up to 20.5 mg QE/g) and pigments (chlorophyll A up to 1.0 g/kg, chlorophyll B up to 0.3 g/kg, and carotenoids up to 0.1 g/kg). This study revealed new bioproducts that express strong antioxidant (reaching IC50 values up to 132.5 mu g/mL) and antimicrobial activity (with minimum inhibitory concentrations up to 80.0 mu g/mL). Among the tested 23 microbial strains, the extracts exhibited the strongest activity against food -borne pathogens Micrococcus luteus and Bacillus subtilis. Furthermore, the antitumor and antiviral activity of separated dandelion biological products was evaluated. (c) 2023 Institution of Chemical Engineers. Published by Elsevier Ltd. All rights reserved.}, keywords = {chemical composition; Bioactive compounds; Valorization; Sequential extraction process; supercritical CO2 extraction; FUNCTIONAL FOOD INGREDIENTS}, year = {2023}, eissn = {1744-3571}, pages = {70-81} } @article{MTMT:34346033, title = {Simultaneous production of xylitol and arabitol by Candida tropicalis fermentation improving agro-industrial wastes valorization}, url = {https://m2.mtmt.hu/api/publication/34346033}, author = {Bevilaqua, Gabriel Cicalese and Maugeri Filho, Francisco and Forte, Marcus Bruno Soares}, doi = {10.1016/j.fbp.2023.04.006}, journal-iso = {FOOD BIOPROD PROCESS}, journal = {FOOD AND BIOPRODUCTS PROCESSING}, volume = {140}, unique-id = {34346033}, issn = {0960-3085}, abstract = {Xylitol and arabitol are sugar alcohols with similar properties and applications. Although the biotechnological production of xylitol is already being explored, its coproduction with arabitol is still in the early stages. This study aimed to improve the coproduction of xylitol and arabitol by Candida tropicalis from sugarcane bagasse hemicellulosic hydrolysate. The most promising results were achieved with 2.2 g L-1 nitrogen, obtained by mixing 80% yeast hydrolysate and 20% corn steep water. For fermentations conducted in a bioreactor, the concentrations of xylitol (52.1 g L-1) and arabitol (4.2 g L-1) were 65 and 3.7 times higher, respectively, than those reported in the literature for similar processes, with productivities and yields of 0.24 g L-1 h-1 and 0.74 g g-1 for xylitol and 0.02 g L-1 h-1 and 0.43 g g-1 for arabitol. These results show promise for the coproduction of sugar alcohols from sugarcane bagasse hemicellulosic hydrolysate by C tropicalis. (c) 2023 Institution of Chemical Engineers. Published by Elsevier Ltd. All rights reserved.}, keywords = {FERMENTATION; Sugar substitutes; Polyols; Biorefinery; Pentose-assimilating yeasts}, year = {2023}, eissn = {1744-3571}, pages = {29-45} } @article{MTMT:34341696, title = {Improved control strategies for the environment within cell culture bioreactors}, url = {https://m2.mtmt.hu/api/publication/34341696}, author = {Jones, Jonathan and Kindembe, Didier and Branton, Harvey and Lawal, Najib and Montero, Eduardo Lopez and Mack, John and Shi, Shuo and Patton, Ron and Montague, Gary}, doi = {10.1016/j.fbp.2023.02.004}, journal-iso = {FOOD BIOPROD PROCESS}, journal = {FOOD AND BIOPRODUCTS PROCESSING}, volume = {138}, unique-id = {34341696}, issn = {0960-3085}, abstract = {This paper describes the development of improved control strategies for the standard environmental conditions in a fed-batch bioreactor used for monoclonal antibody cell culture. The consequences of relying on fixed parameter PID based controllers are considered and poor performance is demonstrated as a consequence of non-linearity and loop interactions. The benefits from adopting a more sophisticated control strategy are considered. Model Predictive Control (MPC) relies on a process model that can be identified from small system perturbations. It considers the predicted longer-term response and consequently can deliver improved control and satisfy user defined constraints. Results from experimental trials demonstrate the capability of MPC and the merits are discussed with regards to industrial application. (c) 2023 The Author(s). Published by Elsevier Ltd on behalf of Institution of Chemical Engineers. This is an open access article under the CC BY license (http://creative}, keywords = {cell culture; Environment; predictive control; Monoclonal antibodies}, year = {2023}, eissn = {1744-3571}, pages = {209-220} } @article{MTMT:34313548, title = {Computational Fluid Dynamics (CFD) modeling of static maceration in view to optimize continuous flow extractions of robinetin and dihydrorobinetin from Robinia pseudoacacia wood}, url = {https://m2.mtmt.hu/api/publication/34313548}, author = {Care, Flore and Sangare, Diakaridia and Bostyn, Stephane and Atwi-Ghaddar, Sirine and Lafite, Pierre and Buron, Frederic}, doi = {10.1016/j.fbp.2023.07.0070960-3085}, journal-iso = {FOOD BIOPROD PROCESS}, journal = {FOOD AND BIOPRODUCTS PROCESSING}, volume = {141}, unique-id = {34313548}, issn = {0960-3085}, abstract = {Computational Fluid Dynamics (CFD) modeling was used to study solid-liquid extraction applied to Robinia pseudoacacia. Experimental and simulation studies on maceration and continuous flow extractions were performed at various solid-solvent ratios and flow rates. To validate the CFD modeling results, parameters such as diffusivity or diffusion coefficient and kinetic parameter of the extracts were estimated from experimental kinetic data. A good agreement was found between the CFD model and the experimental data. The mass diffusivity of the extracts in the liquid phase was 1.7 x 10-7 m2/s (R2 = 0.985) and 1.8 x 10-7 m2/s (R2 = 0.992) for dihydrorobinetin (DHR) and robinetin (Rob). Moreover, the phase change coefficient was 1.2 x 10-4 and 1.6 x 10-4 1/s for DHR and Rob, respectively. In addition, static maceration was combined with continuous flow extraction. The optimal condition was 213 min of static maceration followed by a flow of 1 mL/min for 465 min to obtain yields of 45.18 and 6.64 mg/g DHR and Rob, respectively. & COPY; 2023 Published by Elsevier Ltd on behalf of Institution of Chemical Engineers.}, keywords = {EXTRACTION; Optimization; Robinia pseudoacacia; CFD modeling; Robinetin; Dihydrorobinetin}, year = {2023}, eissn = {1744-3571}, pages = {185-198} } @article{MTMT:34307390, title = {Sequential extraction of almond hull biomass with pulsed electric fields (PEF) and supercritical CO2 for the recovery of lipids, carbohydrates and antioxidants}, url = {https://m2.mtmt.hu/api/publication/34307390}, author = {Salgado-Ramos, Manuel and Marti-Quijal, Francisco J. and Huertas-Alonso, Alberto J. and Sanchez-Verdu, M. Prado and Cravotto, Giancarlo and Moreno, Andres and Barba, Francisco J.}, doi = {10.1016/j.fbp.2023.04.003}, journal-iso = {FOOD BIOPROD PROCESS}, journal = {FOOD AND BIOPRODUCTS PROCESSING}, volume = {139}, unique-id = {34307390}, issn = {0960-3085}, abstract = {This work reports the first example of combined sequential extraction by pulsed electric fields (PEF) (3 kV/cm, 100 kJ/kg, 2 Hz, 100 ms) and supercritical (SC) fluid extraction (SFE) (15 MPa, 25 mL/min, 50 degrees C, 60 min) with CO2 (SC-CO2) for the valorisation of almond hull (AH) biomass. PEF+SFE boosted the efficiency of the protocol up to 77% for total antioxidant capacity and 20% in terms of polyphenols recovery compared to the traditional soaking. Triple-TOF-LC-MS-MS analysis provided the phenolic profiles for the PEF and SCCO2 extracts, observing significant differences in the polyphenol profile according to the technology applied. Additionally, NMR analysis detected the presence of the carbohydrate soluble (mainly glucose, fructose and sucrose) and lipidic fractions, both selectively extracted by PEF or SC-CO2, respectively. Finally, the post-extraction residual solid biomass was characterized by several techniques such as TGA, FT-IR and SEM. For the latter, the formation of surface pores after PEF and a high fibre compaction after SFE was observed. On the other hand, DTG curves allowed to firmly propose concurrent valorisation routes for this solid, in agreement with a zero-waste approach. (c) 2023 The Author(s). Published by Elsevier Ltd on behalf of Institution of Chemical Engineers. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).}, keywords = {chemical composition; Bioactive compounds; Sequential extraction process; waste valorisation; Innovative extraction technologies}, year = {2023}, eissn = {1744-3571}, pages = {216-226} }