@article{MTMT:34759319, title = {Autophagy and UPS pathway contribute to nicotine-induced protection effect in Parkinson’s disease}, url = {https://m2.mtmt.hu/api/publication/34759319}, author = {Ullah, I. and Uddin, S. and Zhao, L. and Wang, X. and Li, H.}, doi = {10.1007/s00221-023-06765-9}, journal-iso = {EXP BRAIN RES}, journal = {EXPERIMENTAL BRAIN RESEARCH}, unique-id = {34759319}, issn = {0014-4819}, year = {2024}, eissn = {1432-1106} } @article{MTMT:34663117, title = {Variability of corticospinal and spinal reflex excitability for the ankle dorsiflexor tibialis anterior across repeated measurements in people with and without incomplete spinal cord injury}, url = {https://m2.mtmt.hu/api/publication/34663117}, author = {Brangaccio, J. A. and Phipps, A. M. and Gemoets, D. E. and Sniffen, J. M. and Thompson, Aiko K.}, doi = {10.1007/s00221-024-06777-z}, journal-iso = {EXP BRAIN RES}, journal = {EXPERIMENTAL BRAIN RESEARCH}, unique-id = {34663117}, issn = {0014-4819}, keywords = {Diurnal rhythm; spinal cord injury; H-Reflex; Motor evoked potential; tibialis anterior}, year = {2024}, eissn = {1432-1106} } @article{MTMT:34651082, title = {The effect of reward expectation on working memory of emotional faces under different levels of cognitive load: an ERP study}, url = {https://m2.mtmt.hu/api/publication/34651082}, author = {Gao, Tian and Liu, Xintong and Geng, Wenting and Yan, Chunping and Wu, Meng and Yang, Lei}, doi = {10.1007/s00221-023-06776-6}, journal-iso = {EXP BRAIN RES}, journal = {EXPERIMENTAL BRAIN RESEARCH}, unique-id = {34651082}, issn = {0014-4819}, keywords = {working memory; event-related potential; N-back task; Emotional face; Reward expectation}, year = {2024}, eissn = {1432-1106} } @article{MTMT:34664552, title = {Investigation of non-invasive focused ultrasound efficacy on depressive-like behavior in hemiparkinsonian rats}, url = {https://m2.mtmt.hu/api/publication/34664552}, author = {Herlihy, Rachael A. and Alicandri, Francisco and Berger, Hudy and Rehman, Huda and Kao, Yifan and Akhtar, Kainat and Dybas, Elizabeth and Mahoney-Rafferty, Emily and Von Stein, Kassie and Kirby, Raven and Tawfik, Angela and Skumurski, Rachel and Feustel, Paul J. and Molho, Eric S. and Shin, Damian S.}, doi = {10.1007/s00221-023-06750-2}, journal-iso = {EXP BRAIN RES}, journal = {EXPERIMENTAL BRAIN RESEARCH}, volume = {242}, unique-id = {34664552}, issn = {0014-4819}, keywords = {DEPRESSION; Parkinson's disease; anhedonia; Forced swim test; sucrose preference test; Peripheral non-invasive focused ultrasound}, year = {2024}, eissn = {1432-1106}, pages = {321-336} } @article{MTMT:34654883, title = {Perceived cognitive fatigue has only marginal effects on static balance control in healthy young adults}, url = {https://m2.mtmt.hu/api/publication/34654883}, author = {Weissinger, Kerstin and Bach, Margit Midtgaard and Brachman, Anna and Stins, John F. and Beek, Peter Jan}, doi = {10.1007/s00221-023-06736-0}, journal-iso = {EXP BRAIN RES}, journal = {EXPERIMENTAL BRAIN RESEARCH}, volume = {242}, unique-id = {34654883}, issn = {0014-4819}, keywords = {Sample entropy; mental fatigue; Cognitive resources; Postural regulation; TloadDback}, year = {2024}, eissn = {1432-1106}, pages = {163-177}, orcid-numbers = {Weissinger, Kerstin/0009-0000-4764-9737; Brachman, Anna/0000-0002-3562-3131} } @article{MTMT:34611987, title = {The P38MAPK/ATF2 signaling pathway is involved in PND in mice}, url = {https://m2.mtmt.hu/api/publication/34611987}, author = {Zhu, Mengjiao and Long, Si and Tao, Yizhi and Zhang, Zhifa and Zhou, Zhiqiang and Wang, Xueren and Chen, Wei}, doi = {10.1007/s00221-023-06730-6}, journal-iso = {EXP BRAIN RES}, journal = {EXPERIMENTAL BRAIN RESEARCH}, volume = {242}, unique-id = {34611987}, issn = {0014-4819}, abstract = {Accumulating evidence indicates that microglia-mediated neuroinflammation in the hippocampus contributes to the development of perioperative neurocognitive disorder (PND). P38MAPK, a point of convergence for different signaling processes involved in inflammation, can be activated by various stresses. This study aims to investigate the role of the P38MAPK/ATF2 signaling pathway in the development of PND in mice. Aged C57BL/6 mice were subjected to tibial fracture surgery under isoflurane anesthesia to establish a PND animal model. The open field test was used to evaluate the locomotor activity of the mice. Neurocognitive function was assessed with the Morris water maze (MWM) and fear conditioning test (FCT) on postoperative days 1, 3 and 7. The mice exhibited cognitive impairment accompanied by increased expression of proinflammatory factors (IL-1 beta, TNF-alpha), proapoptotic molecules (caspase-3, bax) and microglial activation in the hippocampus 1, 3 and 7 days after surgery. Treatment with SB239063 (a P38MAPK inhibitor) decreased the expression of proinflammatory factors, proapoptotic molecules and Iba-1 in the CA1 region of the hippocampus. The number of surviving neurons was significantly increased. Inhibition of the P38MAPK/ATF2 signaling pathway attenuates hippocampal neuroinflammation and neuronal apoptosis in aged mice with PND, thus improving the perioperative cognitive function of the mice.}, keywords = {NEURONAL APOPTOSIS; neuroinflammation; MICROGLIAL ACTIVATION; Perioperative neurocognitive disorders; P38MAPK/ATF2 signaling pathway}, year = {2024}, eissn = {1432-1106}, pages = {109-121} } @article{MTMT:34581580, title = {Back and front peripersonal space: behavioural and EMG evidence of top-down and bottom-up mechanisms}, url = {https://m2.mtmt.hu/api/publication/34581580}, author = {Cocchini, Gianna and Muellensiefen, Daniel and Platania, Ruggero and Niglio, Chiara and Tricomi, Enrica and Veronelli, Laura and Judica, Elda}, doi = {10.1007/s00221-023-06740-4}, journal-iso = {EXP BRAIN RES}, journal = {EXPERIMENTAL BRAIN RESEARCH}, volume = {242}, unique-id = {34581580}, issn = {0014-4819}, abstract = {Previous studies have identified a 'defensive graded field' in the peripersonal front space where potential threatening stimuli induce stronger blink responses, mainly modulated by top-down mechanisms, which include various factors, such as proximity to the body, stimulus valence, and social cues. However, very little is known about the mechanisms responsible for representation of the back space and the possible role of bottom-up information. By means of acoustic stimuli, we evaluated individuals' representation for front and back space in an ambiguous environment that offered some degree of uncertainty in terms of both distance (close vs. far) and front-back egocentric location of sound sources. We aimed to consider verbal responses about localization of sound sources and EMG data on blink reflex. Results suggested that stimulus distance evaluations were better explained by subjective front-back discrimination, rather than real position. Moreover, blink response data were also better explained by subjective front-back discrimination. Taken together, these findings suggest that the mechanisms that dictate blink response magnitude might also affect sound localization (possible bottom-up mechanism), probably interacting with top-down mechanisms that modulate stimuli location and distance. These findings are interpreted within the defensive peripersonal framework, suggesting a close relationship between bottom-up and top-down mechanisms on spatial representation.}, keywords = {EMG; blink reflex; peripersonal space; rear space; Back space}, year = {2024}, eissn = {1432-1106}, pages = {241-255}, orcid-numbers = {Cocchini, Gianna/0000-0002-4789-9661} } @article{MTMT:34563731, title = {The effect and efficiency of attentional networks and the brain electrophysiology}, url = {https://m2.mtmt.hu/api/publication/34563731}, author = {Akbari-Lalimi, H. and Naseri, S. and Momennezhad, M. and Zare, H. and Talaei, A. and Shafiei, S.A.}, doi = {10.1007/s00221-023-06712-8}, journal-iso = {EXP BRAIN RES}, journal = {EXPERIMENTAL BRAIN RESEARCH}, volume = {242}, unique-id = {34563731}, issn = {0014-4819}, abstract = {The attention networks test (ANT) is frequently utilized to evaluate executive, alerting, and orienting attentional components. Additionally, it serves as an activation task in neuroimaging studies. This study aimed to examine the relationship between attention networks and brain electrophysiology. The study enrolled 40 right-handed male students (age = 20.8 ± 1.3 years) who underwent the revised attention network test, while their electroencephalogram signals were recorded. The study aimed to explore the effects of attention networks and their efficiencies on brain electrophysiology. The results indicated that the P3 amplitude was modulated by the conflict effect in the central (p-value = 0.014) and parietal (p-value = 0.002) regions. The orienting component significantly influenced P1 and N1 latencies in the parietal and parieto-occipital regions (p-values < 0.006), as well as P1 and N1 amplitude in the parieto-occipital region (p-values = 0.017 and 0.011). The alerting component significantly affected P1 latency and amplitude in the parietal and parieto-occipital regions, respectively (p-value = 0.02). Furthermore, N1 amplitude and the time interval between P1 and N1 were significantly correlated with the efficiency of alerting and orienting networks. In terms of connectivity, the coherence of theta and alpha bands significantly decreased in the incongruent condition compared to the congruent condition. Additionally, the effects of attention networks on event-related spectral perturbation were observed. The study revealed the influence of attention networks on various aspects of brain electrophysiology. Specifically, the alerting score correlated with the amplitude of the N1 component in the double-cue and no-cue conditions in the parieto-occipital region, while the orienting score in the same region correlated with the N1 amplitude in the valid cue condition and the difference in N1 amplitude between the valid cue and double-cue conditions. Overall, empirical evidence suggests that attention networks not only impact the amplitudes of electrophysiological activities but also influence their time course. © 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.}, keywords = {Brain; Brain; Adult; Adult; Male; Male; Humans; ARTICLE; human; Electrophysiology; Electrophysiology; physiology; controlled study; clinical article; Orientation; Orientation; Electroencephalography; Electroencephalography; Electroencephalogram; Reaction Time; Reaction Time; Young Adult; Young Adult; Diagnostic Imaging; occipital lobe; occipital lobe; Attention; Attention; occipital cortex; event related potential; Orienting; event-related potential; Alerting; Attention network test; Executive}, year = {2024}, eissn = {1432-1106}, pages = {79-97} } @article{MTMT:34386714, title = {The contribution of muscle spindles to position sense measured with three different methods}, url = {https://m2.mtmt.hu/api/publication/34386714}, author = {Roach, Christopher and Love, Christopher and Allen, Trevor and Proske, Uwe}, doi = {10.1007/s00221-023-06689-4}, journal-iso = {EXP BRAIN RES}, journal = {EXPERIMENTAL BRAIN RESEARCH}, unique-id = {34386714}, issn = {0014-4819}, abstract = {The sense of limb position is important, because it is believed to contribute to our sense of self-awareness. Muscle spindles, including both primary and secondary endings of spindles, are thought to be the principal position sensors. Passive spindles possess a property called thixotropy which allows their sensitivity to be manipulated. Here, thixotropic patterns of position errors have been studied with three commonly used methods of measurement of position sense. The patterns of errors have been used as indicators of the influence exerted by muscle spindles on a measured value of position sense. In two-arm matching, the blindfolded participant indicates the location of one arm by placement of the other. In one-arm pointing, the participant points to the perceived position of their other, hidden arm. In repositioning, one of the blindfolded participant's arms is placed at a chosen angle and they are asked to remember its position and then, after a delay, reproduce the position. The three methods were studied over the full range of elbow angles between 5 & DEG; (elbow extension) and 125 & DEG; (elbow flexion). Different outcomes were achieved with each method; in two-arm matching, position errors were symmetrical about zero and thixotropic influences were large, while in one-arm pointing, errors were biased towards extension. In repositioning, thixotropic effects were small. We conclude that each of the methods of measuring position sense comprises different mixes of peripheral and central influences. This will have to be taken into consideration by the clinician diagnosing disturbances in position sense.}, keywords = {proprioception; Thixotropy; Muscle spindle; Self-awareness}, year = {2023}, eissn = {1432-1106}, orcid-numbers = {Allen, Trevor/0000-0002-3911-7914} } @article{MTMT:34276178, title = {The effect of acute exercise on attentional control and theta power in young adults}, url = {https://m2.mtmt.hu/api/publication/34276178}, author = {Griggs, Mark A. and Parr, Brian and Vandegrift, Nathan S. and Jelsone-Swain, Laura}, doi = {10.1007/s00221-023-06660-3}, journal-iso = {EXP BRAIN RES}, journal = {EXPERIMENTAL BRAIN RESEARCH}, unique-id = {34276178}, issn = {0014-4819}, abstract = {Exercise has a profound impact on one's health, and it is becoming increasingly accepted that exercise also benefits cognitive functioning. Yet, the neural mechanism for which cognitive enhancement occurs is less understood. Therefore, the purpose of our study was to experimentally test whether an acute exercise activity was able to increase theta power and behavioral performance during an executive functioning attentional control task. Participants were randomly assigned to either a stationary-bike exercise or a resting control condition. Thereafter, they completed the Eriksen flanker task, and most participants completed this while EEG data were recorded. From the flanker task data, we demonstrated an interaction effect from both accuracy and reaction time measurements. Importantly, the exercise group was more accurate than the control group in incongruent trials. From the EEG data, theta power was overall higher in the exercise group, especially during the congruent trials, compared to controls. Our results add to the limited but growing body of research that suggests acute exercise produces a general increase in theta power, which in turn may play a role in enhancing cognitive performance. These results, combined with previous research, could have widespread implications in multiple settings such as in the investigation of a biomarker of physical fitness, neurorehabilitation, and in education.}, keywords = {EEG; ACUTE EXERCISE; FLANKER TASK; theta power; Attentional control}, year = {2023}, eissn = {1432-1106}, orcid-numbers = {Parr, Brian/0000-0001-7441-8344} }