@article{MTMT:34761820,
	title = {A dog's life: Early life histories influence methylation of glucocorticoid (NR3C1) and oxytocin (OXTR) receptor genes, cortisol levels, and attachment styles},
	url = {https://m2.mtmt.hu/api/publication/34761820},
	author = {Awalt, S.L. and Boghean, L. and Klinkebiel, D. and Strasser, R.},
	doi = {10.1002/dev.22482},
	journal-iso = {DEV PSYCHOBIOL},
	journal = {DEVELOPMENTAL PSYCHOBIOLOGY},
	volume = {66},
	unique-id = {34761820},
	issn = {0012-1630},
	abstract = {Early life deprivation and stress can contribute to life-long, problematic consequences, including epigenetic variations related to behavior and health. Domestic dogs share human environments and social–cognitive traits, making them a promising comparative model to examine developmental plasticity. We examined 47 owner–dog dyads, including dogs rescued from abusive or neglectful environments, and matched control dogs for changes in DNA methylation of glucocorticoid (NR3C1) and oxytocin (OXTR) receptor genes previously shown to be affected by early life stress in other species including humans. We used an attachment paradigm, which included a separation event to examine cortisol levels and owner–dog attachment styles. Overall, dogs with adverse histories had different NR3C1 methylation patterns as a function of age and less OXTR methylation than comparison dogs. Dogs with adverse histories did not differ in their cortisol change from baseline to poststressor from comparison dogs, but the change in cortisol was associated with NR3C1 methylation. In addition, dogs with a history of early life stress had more insecure attachment styles; for every unit increase of OXTR methylation, the odds increased for insecure attachment style. This study demonstrates that adverse life histories lead to methylation differences, resulting in the hypothalamic–pituitary–adrenal (HPA) axis's dysregulation and differences in behavioral phenotypes. © 2024 The Authors. Developmental Psychobiology published by Wiley Periodicals LLC.},
	keywords = {Dogs; Animals; Humans; metabolism; GENETICS; GLUCOCORTICOID RECEPTOR; OXYTOCIN; OXYTOCIN; METHYLATION; human; animal; dog; dog; CORTISOL; GLUCOCORTICOIDS; hydrocortisone; hydrocortisone; glucocorticoid; DNA methylation; DNA methylation; attachment; Receptors, Glucocorticoid; epigenetics; Receptors, Oxytocin; early life stress; oxytocin receptor; Strange Situation Procedure; OXTR protein, human; NR3C1 protein, human},
	year = {2024},
	eissn = {1098-2302}
}

@article{MTMT:34662049,
	title = {Maternal high-fat diet associated with LPS gestational injection induces hypothalamic inflammation and metabolic disorders in male Wistar rat offspring},
	url = {https://m2.mtmt.hu/api/publication/34662049},
	author = {Rocha-Gomes, Arthur and Escobar Teixeira, Amanda and da Silva, Alexandre Alves and da Silva, Mariana Muniz and Santos, Tatielly Roberta and Castro, Tulio Pereira Alvarenga e and Lessa, Mayara Rodrigues and Villela, Daniel Campos and Riul, Tania Regina and Leite, Hercules Ribeiro},
	doi = {10.1002/dev.22462},
	journal-iso = {DEV PSYCHOBIOL},
	journal = {DEVELOPMENTAL PSYCHOBIOLOGY},
	volume = {66},
	unique-id = {34662049},
	issn = {0012-1630},
	keywords = {Cytokines; OBESITY; lactation; REDOX STATE; sucrose preference},
	year = {2024},
	eissn = {1098-2302}
}

@article{MTMT:34649213,
	title = {Letter to the Editor: Does fetal movement shape the maternal brain?},
	url = {https://m2.mtmt.hu/api/publication/34649213},
	author = {Ayala, Kathy and Voegtline, Kristin and Rutherford, Helena J. V},
	doi = {10.1002/dev.22467},
	journal-iso = {DEV PSYCHOBIOL},
	journal = {DEVELOPMENTAL PSYCHOBIOLOGY},
	volume = {66},
	unique-id = {34649213},
	issn = {0012-1630},
	year = {2024},
	eissn = {1098-2302}
}

@article{MTMT:34611035,
	title = {Developmental windows for effects of choline and folate on excitatory and inhibitory neurotransmission during human gestation},
	url = {https://m2.mtmt.hu/api/publication/34611035},
	author = {Hunter, Sharon K. and Hoffman, M. Camille and D'Alessandro, Angelo and Freedman, Robert},
	doi = {10.1002/dev.22453},
	journal-iso = {DEV PSYCHOBIOL},
	journal = {DEVELOPMENTAL PSYCHOBIOLOGY},
	volume = {66},
	unique-id = {34611035},
	issn = {0012-1630},
	abstract = {Choline and folate are critical nutrients for fetal brain development, but the timing of their influence during gestation has not been previously characterized. At different periods during gestation, choline stimulation of alpha 7-nicotinic receptors facilitates the conversion of gamma-aminobutyric acid (GABA) receptors from excitatory to inhibitory and recruitment of GluR1-R2 receptors for faster excitatory responses to glutamate. The outcome of the fetal development of inhibition and excitation was assessed in 159 newborns by P50 cerebral auditory-evoked responses. Paired stimuli, S1 and S2, were presented 500 ms apart. Higher P50 amplitude in response to S1 (P50S1microV) assesses excitation, and lower P50S2microV assesses inhibition in this paired-stimulus paradigm. The development of inhibition was related solely to maternal choline plasma concentration and folate supplementation at 16 weeks' gestation. The development of excitation was related only to maternal choline at 28 weeks. Higher maternal choline concentrations later in gestation did not compensate for earlier lower concentrations. At 4 years of age, increased behavior problems on the Child Behavior Checklist 1.5-5 years were related to both newborn inhibition and excitation. The incomplete development of inhibition and excitation associated with lower choline and folate during relatively brief periods of gestation thus has enduring effects on child development.},
	keywords = {Brain; INHIBITION; hippocampus; human; pregnancy; EXCITATION; phosphatidylcholine; Choline; Attention; Fetal Development; evoked potentials auditory},
	year = {2024},
	eissn = {1098-2302}
}

@article{MTMT:34594227,
	title = {An in-depth analysis of the polyvagal theory in light of current findings in neuroscience and clinical research},
	url = {https://m2.mtmt.hu/api/publication/34594227},
	author = {Manzotti, Andrea and Panisi, Cristina and Pivotto, Micol and Vinciguerra, Federico and Benedet, Matteo and Brazzoli, Federica and Zanni, Silvia and Comassi, Alberto and Caputo, Sara and Cerritelli, Francesco and Chiera, Marco},
	doi = {10.1002/dev.22450},
	journal-iso = {DEV PSYCHOBIOL},
	journal = {DEVELOPMENTAL PSYCHOBIOLOGY},
	volume = {66},
	unique-id = {34594227},
	issn = {0012-1630},
	abstract = {The polyvagal theory has led to the understanding of the functions of the autonomic nervous system in biological development in humans, since the vagal system, a key structure within the polyvagal theory, plays a significant role in addressing challenges of the mother-child dyad. This article aims to summarize the neurobiological aspects of the polyvagal theory, highlighting some of its strengths and limitations through the lens of new evidence emerging in several research fields-including comparative anatomy, embryology, epigenetics, psychology, and neuroscience-in the 25 years since the theory's inception. Rereading and incorporating the polyvagal idea in light of modern scientific findings helps to interpret the role of the vagus nerve through the temporal dimension (beginning with intrauterine life) and spatial dimension (due to the numerous connections of the vagus with various structures and systems) in the achievement and maintenance of biopsychosocial well-being, from the uterus to adulthood.},
	keywords = {autonomic nervous system; empathy; VAGUS NERVE; Interoception; HRV; Neuroception; polyvagal theory; interaction parent-child},
	year = {2024},
	eissn = {1098-2302}
}

@article{MTMT:34593912,
	title = {The role of fathers in child development from preconception to postnatal influences: Opportunities for the National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) program},
	url = {https://m2.mtmt.hu/api/publication/34593912},
	author = {Jansen, Elena and Marceau, Kristine and Sellers, Ruth and Chen, Tong and Garfield, Craig F. and Leve, Leslie D. and Neiderhiser, Jenae M. and Spotts, Erica L. and Roary, Mary},
	doi = {10.1002/dev.22451},
	journal-iso = {DEV PSYCHOBIOL},
	journal = {DEVELOPMENTAL PSYCHOBIOLOGY},
	volume = {66},
	unique-id = {34593912},
	issn = {0012-1630},
	abstract = {A growing body of literature highlights the important role of paternal health and socioemotional characteristics in child development, from preconception through adolescence. Much of this research addresses the indirect effects of fathers, for instance, their influence on maternal behaviors during the prenatal period or via the relationship with their partner. However, emerging evidence also recognizes the direct role of paternal health and behavior for child health and adjustment across development. This critical review presents evidence of biological and sociocultural influences of fathers on preconception, prenatal, and postnatal contributions to child development. The National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) program incorporates in its central conceptualization the impact of fathers on family and child outcomes. This critical synthesis of the literature focuses on three specific child outcomes in the ECHO program: health outcomes (e.g., obesity), neurodevelopmental outcomes (e.g., emotional, behavioral, psychopathological development), and positive health. We highlight the unique insights gained from the literature to date and provide next steps for future studies on paternal influences.},
	keywords = {OBESITY; Prenatal; father; Child Development; Postnatal; neurodevelopment; preconception; Positive health},
	year = {2024},
	eissn = {1098-2302},
	orcid-numbers = {Chen, Tong/0000-0001-8443-0590}
}

@article{MTMT:34627419,
	title = {Behavioral responses to natural rewards in developing male and female rats},
	url = {https://m2.mtmt.hu/api/publication/34627419},
	author = {Oak, Sasha and Nguyen, Christine and Rodney-Hernandez, Paolaenid and Rincon-Cortes, Millie},
	doi = {10.1002/dev.22448},
	journal-iso = {DEV PSYCHOBIOL},
	journal = {DEVELOPMENTAL PSYCHOBIOLOGY},
	volume = {66},
	unique-id = {34627419},
	issn = {0012-1630},
	keywords = {SEX; Development; sucrose; adolescence; Reward; play; Palatable food},
	year = {2024},
	eissn = {1098-2302}
}

@article{MTMT:34601136,
	title = {Emotion dysregulation and reward responsiveness as predictors of autonomic reactivity to an infant cry task among substance-using pregnant and postpartum women},
	url = {https://m2.mtmt.hu/api/publication/34601136},
	author = {Bounoua, Nadia and Tabachnick, Alexandra R. and Eiden, Rina D. and Labella, Madelyn H. and Dozier, Mary},
	doi = {10.1002/dev.22449},
	journal-iso = {DEV PSYCHOBIOL},
	journal = {DEVELOPMENTAL PSYCHOBIOLOGY},
	volume = {66},
	unique-id = {34601136},
	issn = {0012-1630},
	abstract = {Maternal substance use may interfere with optimal parenting, lowering maternal responsiveness during interactions with their children. Previous work has identified maternal autonomic nervous system (ANS) reactivity to parenting-relevant stressors as a promising indicator of real-world parenting behaviors. However, less is known about the extent to which individual differences in emotion dysregulation and reward processing, two mechanisms of substance use, relate to maternal ANS reactivity in substance-using populations. The current study examined associations among emotion dysregulation, reward responsiveness, and ANS reactivity to an infant cry task among 77 low-income and substance-using women who were either pregnant (n = 63) or postpartum (n = 14). Two indicators of ANS functioning were collected during a 9 min computerized infant cry task (Crybaby task): respiratory sinus arrhythmia (RSA) and pre-ejection period. Mothers also completed self-reported measures of emotion dysregulation and reward responsiveness. Analyses revealed that trait emotion regulation was associated with RSA reactivity to the Crybaby task, such that greater emotion dysregulation was associated with greater RSA reduction during the infant cry task than lower emotion dysregulation. Reward responsiveness was not significantly associated with either indicator of ANS reactivity to the task. Findings revealed distinct patterns of associations linking emotion dysregulation with ANS reactivity during a parenting-related computerized task, suggesting that emotion regulation may be a key intervention target for substance-using mothers.},
	keywords = {Prenatal; parenting; RESPIRATORY SINUS ARRHYTHMIA; pre-ejection period; VAGAL REGULATION},
	year = {2024},
	eissn = {1098-2302},
	orcid-numbers = {Bounoua, Nadia/0000-0001-9310-3049}
}

@article{MTMT:34510676,
	title = {Maternal psychological risk and the neural correlates of infant face processing: A latent profile analysis},
	url = {https://m2.mtmt.hu/api/publication/34510676},
	author = {Wall, K.M. and Penner, F. and Dell, J. and Lowell, A. and Potenza, M.N. and Mayes, L.C. and Rutherford, H.J.V.},
	doi = {10.1002/dev.22445},
	journal-iso = {DEV PSYCHOBIOL},
	journal = {DEVELOPMENTAL PSYCHOBIOLOGY},
	volume = {66},
	unique-id = {34510676},
	issn = {0012-1630},
	year = {2024},
	eissn = {1098-2302}
}

@article{MTMT:34556707,
	title = {Maternal care behavior and physiology moderate offspring outcomes following gestational exposure to opioids},
	url = {https://m2.mtmt.hu/api/publication/34556707},
	author = {Myers, A.M. and Bowen, S.E. and Brummelte, S.},
	doi = {10.1002/dev.22433},
	journal-iso = {DEV PSYCHOBIOL},
	journal = {DEVELOPMENTAL PSYCHOBIOLOGY},
	volume = {65},
	unique-id = {34556707},
	issn = {0012-1630},
	abstract = {The opioid epidemic has resulted in a drastic increase in gestational exposure to opioids. Opioid-dependent pregnant women are typically prescribed medications for opioid use disorders (“MOUD”; e.g., buprenorphine [BUP]) to mitigate the harmful effects of abused opioids. However, the consequences of exposure to synthetic opioids, particularly BUP, during gestation on fetal neurodevelopment and long-term outcomes are poorly understood. Further, despite the known adverse effects of opioids on maternal care, many preclinical and clinical studies investigating the effects of gestational opioid exposure on offspring outcomes fail to report on maternal care behaviors. Considering that offspring outcomes are heavily dependent upon the quality of maternal care, it is important to evaluate the effects of gestational opioid exposure in the context of the mother−infant dyad. This review compares offspring outcomes after prenatal opioid exposure and after reduced maternal care and integrates this information to potentially identify common underlying mechanisms. We explore whether adverse outcomes after gestational BUP exposure are due to direct effects of opioids in utero, deficits in maternal care, or a combination of both factors. Finally, suggestions for improving preclinical models of prenatal opioid exposure are provided to promote more translational studies that can help to improve clinical outcomes for opioid-dependent mothers. © 2023 Wiley Periodicals LLC.},
	year = {2023},
	eissn = {1098-2302}
}