https://m2.mtmt.hu/
hun
2024-03-28 10:52
false
true
82
811
811
640
10
1
10
DESC
publishedYear
false
DESC
issue
false
JournalArticle
34657623
VALIDATED
true
0
false
2024-02-21T14:05:16.668+0000
2024-02-21T13:28:02.830+0000
2024-02-21T13:28:02.003+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
2024-02-21T13:28:01.826+0000
2024-02-21T13:28:01.826+0000
2024-02-21T13:28:02.051+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
false
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Yan, Jin-Hua
LncRNA AL645608.3 mediates malignant progression of acute myeloid leukemia
true
true
/api/journal/10032933
REVIEWED
true
false
10032933
false
10032933
true
1943-8141
1943-8141
Journal
FOREIGN
16
1
342
355
342
14
2024
2024
true
true
true
false
false
GOLD
2024-02-21
false
http://www.ajtr.org
0
0
0
0
0
0
0
0
0
0
0
0
1
1
false
false
false
false
1
11
0
6
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
115062278
/api/authorship/115062278
1
0.16666667
true
false
false
Yan
Jin-Hua
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
115062279
/api/authorship/115062279
2
0.16666667
false
false
false
Liao
Kai-Qiong
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
115062280
/api/authorship/115062280
3
0.16666667
false
false
false
Yao
Ling
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
115062281
/api/authorship/115062281
4
0.16666667
false
false
false
Chen
Jian-Lan
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
115062282
/api/authorship/115062282
5
0.16666667
false
false
false
Xiong
Li-Fang
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
115062283
/api/authorship/115062283
6
0.16666667
false
true
true
Tao
Xu-Zhang
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
25664361
/api/publicationidentifier/25664361
IDENTICAL
001157816300001
https://www.webofscience.com/wos/woscc/full-record/001157816300001
false
true
Classification
12125
/api/classification/12125
true
true
Classification
12215
/api/classification/12215
true
true
Keyword
1028432
/api/keyword/1028432
true
1028432
true
Keyword
1388558
/api/keyword/1388558
true
1388558
true
Keyword
1493484
/api/keyword/1493484
true
true
Keyword
1688737
/api/keyword/1688737
true
true
Keyword
1720371
/api/keyword/1720371
true
true
Keyword
3340536
/api/keyword/3340536
true
true
Keyword
3340537
/api/keyword/3340537
true
true
/api/publication/34657623
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Yan, Jin-Hua </span> <span class="author-type"> </span> ; <span class="author-name" > Liao, Kai-Qiong </span> <span class="author-type"> </span> ; <span class="author-name" > Yao, Ling </span> <span class="author-type"> </span> ; <span class="author-name" > Chen, Jian-Lan </span> <span class="author-type"> </span> ; <span class="author-name" > Xiong, Li-Fang </span> <span class="author-type"> </span> ; <span class="author-name" > Tao, Xu-Zhang ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34657623" mtid="34657623" target="_blank">LncRNA AL645608.3 mediates malignant progression of acute myeloid leukemia</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-volume">16</span> : <span class="journal-issue">1</span> <span class="page"> pp. 342-355. , 14 p. </span> <span class="year">(2024)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001157816300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001157816300001"> WoS </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34657623 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" >Yan Jin-Hua
</span>
;
<span class="author-name" >Liao Kai-Qiong
</span>
;
<span class="author-name" >Yao Ling
</span>
;
<span class="author-name" >Chen Jian-Lan
</span>
;
<span class="author-name" >Xiong Li-Fang
</span>
;
<span class="author-name" >Tao Xu-Zhang ✉
</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34657623" target="_blank">LncRNA AL645608.3 mediates malignant progression of acute myeloid leukemia</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a>)</span>:
<span class="journal-volume">16</span> <span class="journal-issue">1</span>
<span class="page">
pp 342-355
</span> <span class="year">(2024)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Nyelv:
Angol
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="001157816300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001157816300001">
WoS
</a>
</span>
</span>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;34657623&sort=publishedYear,desc&sort=title">
Idézett közlemények száma: 1
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Közlemény: 34657623</span>
| <span class="status-data status-VALIDATED"> Egyeztetett
</span>
Idéző
| <span class="type-subtype">Folyóiratcikk
( Szakcikk
)
</span>
| <span class="pub-category">Tudományos</span>
| <span class="publication-sourceOfData">WoS-XML</span>
</div>
<div class="lastModified">Utolsó módosítás: 2024.02.21. 14:28 Szuper Admin (admin)
</div>
</div></div>
JournalArticle
34665764
VALIDATED
true
0
false
2024-02-22T05:27:45.529+0000
2024-02-22T05:26:31.777+0000
2024-02-22T05:26:30.878+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
2024-02-22T05:26:30.712+0000
2024-02-22T05:26:30.712+0000
2024-02-22T05:26:30.935+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
false
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Wang, Tongling
Comparative analysis of ankle injury kinematics and dynamics in basketball players: forefoot landing vs. rearfoot landing modes
true
true
/api/journal/10032933
REVIEWED
true
false
10032933
false
10032933
true
1943-8141
1943-8141
Journal
FOREIGN
15
9
5843
5849
5843
7
2023
2024
true
true
true
false
false
GOLD
2024-02-22
false
http://www.ajtr.org
0
0
0
0
0
0
0
0
0
0
0
0
1
1
false
false
false
false
2
2
0
3
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
115128848
/api/authorship/115128848
1
0.33333334
true
false
false
Wang
Tongling
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
115128849
/api/authorship/115128849
2
0.33333334
false
false
false
Zhao
Cuiqing
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
115128850
/api/authorship/115128850
3
0.33333334
false
true
true
Guo
Zhangjian
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
25694832
/api/publicationidentifier/25694832
IDENTICAL
001156707800011
https://www.webofscience.com/wos/woscc/full-record/001156707800011
false
true
Classification
12125
/api/classification/12125
true
true
Classification
12215
/api/classification/12215
true
true
Keyword
9013
/api/keyword/9013
true
9013
true
Keyword
1004951
/api/keyword/1004951
true
1004951
true
Keyword
1035897
/api/keyword/1035897
true
1035897
true
Keyword
3267479
/api/keyword/3267479
true
true
Keyword
3345759
/api/keyword/3345759
true
true
/api/publication/34665764
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Wang, Tongling </span> <span class="author-type"> </span> ; <span class="author-name" > Zhao, Cuiqing </span> <span class="author-type"> </span> ; <span class="author-name" > Guo, Zhangjian ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34665764" mtid="34665764" target="_blank">Comparative analysis of ankle injury kinematics and dynamics in basketball players: forefoot landing vs. rearfoot landing modes</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-volume">15</span> : <span class="journal-issue">9</span> <span class="page"> pp. 5843-5849. , 7 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001156707800011" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001156707800011"> WoS </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34665764 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" >Wang Tongling
</span>
;
<span class="author-name" >Zhao Cuiqing
</span>
;
<span class="author-name" >Guo Zhangjian ✉
</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34665764" target="_blank">Comparative analysis of ankle injury kinematics and dynamics in basketball players: forefoot landing vs. rearfoot landing modes</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a>)</span>:
<span class="journal-volume">15</span> <span class="journal-issue">9</span>
<span class="page">
pp 5843-5849
</span> <span class="year">(2023)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Nyelv:
Angol
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="001156707800011" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001156707800011">
WoS
</a>
</span>
</span>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;34665764&sort=publishedYear,desc&sort=title">
Idézett közlemények száma: 1
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Közlemény: 34665764</span>
| <span class="status-data status-VALIDATED"> Egyeztetett
</span>
Idéző
| <span class="type-subtype">Folyóiratcikk
( Szakcikk
)
</span>
| <span class="pub-category">Tudományos</span>
| <span class="publication-sourceOfData">WoS-XML</span>
</div>
<div class="lastModified">Utolsó módosítás: 2024.02.22. 06:26 Szuper Admin (admin)
</div>
</div></div>
JournalArticle
34636173
VALIDATED
true
0
false
2024-02-19T20:37:49.599+0000
2024-02-19T20:36:28.702+0000
2024-02-19T20:36:27.801+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
2024-02-19T20:36:27.641+0000
2024-02-19T20:36:27.641+0000
2024-02-19T20:36:27.942+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
false
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Chen, Fuying
Ulinastatin combined with somatostatin enhances disease control and modulates serum inflammatory factors in patients with severe pancreatitis
true
true
/api/journal/10032933
REVIEWED
true
false
10032933
false
10032933
true
1943-8141
1943-8141
Journal
FOREIGN
15
9
5797
5807
5797
11
2023
2024
true
true
true
false
false
GOLD
2024-02-19
false
http://www.ajtr.org
0
0
0
0
0
0
0
0
0
0
0
0
1
1
false
false
false
false
2
5
0
3
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
114869877
/api/authorship/114869877
1
0.33333334
true
false
false
Chen
Fuying
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114869878
/api/authorship/114869878
2
0.33333334
false
false
true
Xu
Yan
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114869879
/api/authorship/114869879
3
0.33333334
false
true
false
Wang
Zhen
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
25616729
/api/publicationidentifier/25616729
IDENTICAL
001156707800007
https://www.webofscience.com/wos/woscc/full-record/001156707800007
false
true
Classification
12125
/api/classification/12125
true
true
Classification
12215
/api/classification/12215
true
true
Keyword
1215
/api/keyword/1215
true
1215
true
Keyword
1495583
/api/keyword/1495583
true
true
Keyword
1556314
/api/keyword/1556314
true
true
Keyword
1603420
/api/keyword/1603420
true
true
Keyword
2496883
/api/keyword/2496883
true
true
/api/publication/34636173
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Chen, Fuying </span> <span class="author-type"> </span> ; <span class="author-name" > Xu, Yan ✉ </span> <span class="author-type"> </span> ; <span class="author-name" > Wang, Zhen </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34636173" mtid="34636173" target="_blank">Ulinastatin combined with somatostatin enhances disease control and modulates serum inflammatory factors in patients with severe pancreatitis</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-volume">15</span> : <span class="journal-issue">9</span> <span class="page"> pp. 5797-5807. , 11 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001156707800007" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001156707800007"> WoS </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34636173 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" >Chen Fuying
</span>
;
<span class="author-name" >Xu Yan ✉
</span>
;
<span class="author-name" >Wang Zhen
</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34636173" target="_blank">Ulinastatin combined with somatostatin enhances disease control and modulates serum inflammatory factors in patients with severe pancreatitis</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a>)</span>:
<span class="journal-volume">15</span> <span class="journal-issue">9</span>
<span class="page">
pp 5797-5807
</span> <span class="year">(2023)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Nyelv:
Angol
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="001156707800007" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001156707800007">
WoS
</a>
</span>
</span>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;34636173&sort=publishedYear,desc&sort=title">
Idézett közlemények száma: 1
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Közlemény: 34636173</span>
| <span class="status-data status-VALIDATED"> Egyeztetett
</span>
Idéző
| <span class="type-subtype">Folyóiratcikk
( Szakcikk
)
</span>
| <span class="pub-category">Tudományos</span>
| <span class="publication-sourceOfData">WoS-XML</span>
</div>
<div class="lastModified">Utolsó módosítás: 2024.02.19. 21:36 Szuper Admin (admin)
</div>
</div></div>
JournalArticle
34506165
APPROVED
true
Funding Agency and Grant Number: National Natural Science Foundation of China [822-60887]; Guangxi Natural Science Foundation [2020GXNSFAA259068]; first batch of high-level talent research projects of the hospital affiliated to the Right River Ethnic Medical College [R20196321]; Guangxi Medical and Health Appropriate Technology Development and Application Project [YZCXJH2022004]; Innovation Program for Master's Degree Students of Right River School of Ethnic Medicine; [S201917]
Funding text: This work was supported by the National Natural Science Foundation of China (822-60887) , Guangxi Natural Science Foundation (2020GXNSFAA259068) , The first batch of high-level talent research projects of the hospital affiliated to the Right River Ethnic Medical College (R20196321) , Innovation Program for Master's Degree Students of Right River School of Ethnic Medicine (YZCXJH2022004) , and Guangxi Medical and Health Appropriate Technology Development and Application Project (S201917) .
0
false
2024-01-16T09:59:31.017+0000
2024-01-16T09:53:17.902+0000
2024-01-16T09:52:28.486+0000
true
10015206
Áncsán
Gizella
/api/admin/10015206
Admin
true
10015206
2024-01-16T09:53:18.284+0000
2024-01-16T09:53:18.284+0000
false
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Zhou, Haidong
Pan-cancer analysis of the oncogenic role of the core osteosarcoma gene VCAN in human tumors
true
true
/api/journal/10032933
REVIEWED
true
false
10032933
false
10032933
true
1943-8141
1943-8141
Journal
FOREIGN
15
9
5556
5573
5556
18
2023
Objective: Versican (VCAN), a member of the multifunctional glycoprotein family, is involved in various aspects of cancer progression. However, the role of VCAN in diverse cancers remains poorly defined. This research aimed to investigate the correlation between VCAN expression and the oncogenic role, as well as visualize its prognostic landscape in pan-cancer. Methods: Raw data in regard to VCAN expression in cancer patients were acquired from GEO GeneChip public database in NCBI. Besides, we selected microarray data GSE16088 for analysis. We retrieved the genes associated with osteosarcoma (OS) from the OMIM database and identified their intersection with the core module. VCAN was suggested to be a potential marker gene for OS. Subsequently, we conducted Gene Set Enrichment Analysis (GSEA) to explore gene functional enrichment. Moreover, we performed pan-cancer analysis on VCAN to gain a comprehensive understanding of its implications across various cancer types. Results: The VCAN expression in the tumor tissue was higher than that in normal tissue. Elevated expression of VCAN was associated with high the tumor stage and poor long-term survival. There was a significant positive correlation between VCAN and cancer fibroblasts in all pan cancers. Moreover, FBN1 was the intersection gene of VCAN-related genes and linker genes. ANTXR1, COL5A2, CSGALNACT2, and SPARC were the target genes of VCAN genes. GSEA analysis showed that VCAN was mainly enriched in the extracellular matrix (ECM) signaling pathway. Conclusion: VCAN can be used as a marker molecule for the early diagnosis of OS and holds significance as a molecule in cases of OS with distant metastasis. The ECM signaling pathway may be a core pathway in OS development and distant metastasis. These findings shed new light on therapeutics of cancers.
2024
true
true
true
false
false
GOLD
2024-01-16
false
http://www.ajtr.org
0
0
0
0
0
0
0
0
0
0
0
0
1
1
false
false
false
false
2024-04-15T08:53:17.707+0000
2
14
0
13
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
113893988
/api/authorship/113893988
1
0.07692308
true
false
false
Zhou
Haidong
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893989
/api/authorship/113893989
2
0.07692308
false
false
false
Lu
Dinggui
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893990
/api/authorship/113893990
3
0.07692308
false
false
false
Yu
Dianbo
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893991
/api/authorship/113893991
4
0.07692308
false
false
false
Luo
Changtai
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893992
/api/authorship/113893992
5
0.07692308
false
false
false
Xie
Kangqi
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893993
/api/authorship/113893993
6
0.07692308
false
false
false
Ma
Huade
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893994
/api/authorship/113893994
7
0.07692308
false
false
false
Li
Shanlang
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893995
/api/authorship/113893995
8
0.07692308
false
false
false
Liang
Jiyun
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893996
/api/authorship/113893996
9
0.07692308
false
false
false
Wei
Fengxu
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893997
/api/authorship/113893997
10
0.07692308
false
false
false
Chen
Luchang
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893998
/api/authorship/113893998
11
0.07692308
false
false
false
Luo
Dong
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113893999
/api/authorship/113893999
12
0.07692308
false
false
false
Wang
Wei
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113894000
/api/authorship/113894000
13
0.07692308
false
true
true
Wei
Jihua
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
25298102
/api/publicationidentifier/25298102
001089038300002
https://www.webofscience.com/wos/woscc/full-record/001089038300002
false
true
PublicationIdentifier
25298103
/api/publicationidentifier/25298103
37854213
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37854213&dopt=Abstract
false
true
Keyword
223
/api/keyword/223
true
223
true
Keyword
366
/api/keyword/366
true
366
true
Keyword
1607
/api/keyword/1607
true
1607
true
Keyword
2702
/api/keyword/2702
true
2702
true
Keyword
2871
/api/keyword/2871
true
2871
true
Keyword
4710
/api/keyword/4710
true
4710
true
Keyword
17193
/api/keyword/17193
true
17193
true
Keyword
1032351
/api/keyword/1032351
true
1032351
true
Keyword
1052840
/api/keyword/1052840
true
1052840
true
Keyword
1076603
/api/keyword/1076603
true
1076603
true
Keyword
1220352
/api/keyword/1220352
true
1220352
true
Keyword
1632392
/api/keyword/1632392
true
true
Keyword
2493232
/api/keyword/2493232
true
true
Keyword
3282287
/api/keyword/3282287
true
true
/api/publication/34506165
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Zhou, Haidong </span> <span class="author-type"> </span> ; <span class="author-name" > Lu, Dinggui </span> <span class="author-type"> </span> ; <span class="author-name" > Yu, Dianbo </span> <span class="author-type"> </span> ; <span class="author-name" > Luo, Changtai </span> <span class="author-type"> </span> ; <span class="author-name" > Xie, Kangqi </span> <span class="author-type"> </span> ; <span class="author-name" > Ma, Huade </span> <span class="author-type"> </span> ; <span class="author-name" > Li, Shanlang </span> <span class="author-type"> </span> ; <span class="author-name" > Liang, Jiyun </span> <span class="author-type"> </span> ; <span class="author-name" > Wei, Fengxu </span> <span class="author-type"> </span> ; <span class="author-name" > Chen, Luchang </span> <span class="author-type"> </span> et al. </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34506165" mtid="34506165" target="_blank">Pan-cancer analysis of the oncogenic role of the core osteosarcoma gene VCAN in human tumors</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-volume">15</span> : <span class="journal-issue">9</span> <span class="page"> pp. 5556-5573. , 18 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="001089038300002" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001089038300002"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="37854213" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37854213&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34506165 </span> <span class="status-holder"><span class="status-data status-APPROVED"> Nyilvános </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" >Zhou Haidong
</span>
;
<span class="author-name" >Lu Dinggui
</span>
;
<span class="author-name" >Yu Dianbo
</span>
;
<span class="author-name" >Luo Changtai
</span>
;
<span class="author-name" >Xie Kangqi
</span>
;
<span class="author-name" >Ma Huade
</span>
;
<span class="author-name" >Li Shanlang
</span>
;
<span class="author-name" >Liang Jiyun
</span>
;
<span class="author-name" >Wei Fengxu
</span>
;
<span class="author-name" >Chen Luchang
</span>
;
<span class="author-name" >Luo Dong
</span>
;
<span class="author-name" >Wang Wei
</span>
;
<span class="author-name" >Wei Jihua ✉
</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34506165" target="_blank">Pan-cancer analysis of the oncogenic role of the core osteosarcoma gene VCAN in human tumors</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a>)</span>:
<span class="journal-volume">15</span> <span class="journal-issue">9</span>
<span class="page">
pp 5556-5573
</span> <span class="year">(2023)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Nyelv:
Angol
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:black" title="001089038300002" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001089038300002">
WoS
</a>
</span>
<span class="id identifier oa_none" title="none">
<a style="color:black" title="37854213" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37854213&dopt=Abstract">
PubMed
</a>
</span>
</span>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;34506165&sort=publishedYear,desc&sort=title">
Idézett közlemények száma: 1
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Közlemény: 34506165</span>
| <span class="status-data status-APPROVED"> Nyilvános
</span>
Idéző
| <span class="type-subtype">Folyóiratcikk
( Szakcikk
)
</span>
| <span class="pub-category">Tudományos</span>
| <span class="publication-sourceOfData">WOS TAGGED</span>
</div>
<div class="lastModified">Utolsó módosítás: 2024.01.16. 10:53 Áncsán Gizella (SE admin)
</div>
<pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Funding Agency and Grant Number: National Natural Science Foundation of China [822-60887]; Guangxi Natural Science Foundation [2020GXNSFAA259068]; first batch of high-level talent research projects of the hospital affiliated to the Right River Ethnic Medical College [R20196321]; Guangxi Medical and Health Appropriate Technology Development and Application Project [YZCXJH2022004]; Innovation Pro...</pre>
</div></div>
JournalArticle
34323706
VALIDATED
true
0
false
2023-11-14T08:25:36.266+0000
2023-11-14T08:20:52.267+0000
2023-11-14T08:20:50.239+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
2023-11-14T08:20:50.114+0000
2023-11-14T08:20:50.114+0000
2023-11-14T08:20:50.329+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
false
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Sun, Xiaoxia
Levosimendan improves cardiac function, hemodynamics, and body inflammation in patients with acute myocardial infarction and heart failure
true
true
/api/journal/10032933
REVIEWED
true
false
10032933
false
10032933
true
1943-8141
1943-8141
Journal
FOREIGN
15
9
5624
5632
5624
9
2023
Objective: To examine the effects of levosimendan on cardiac function, hemodynamics, and body inflammation of patients with acute myocardial infarction and heart failure. Methods: A retrospective analysis was conducted on 113 acute myocardial infarction patients with heart failure (admitted to Xianyang First People's Hospital from September 2018 to January 2022). According to the treatment plan, patients were categorized into a control group (n = 53) (treated with conventional diuresis and vasodilation) and observation group (n = 60) (treated with levosimendan in addition to the treatment of the control group). Indexes were compared between the two groups before and after treatment, including effectiveness rate, mean pulmonary arterial pressure (PAMP) and pulmonary eter (LVESD) and left ventricular ejection fraction (LVEF) were monitored before and after treatment by color Doppler ultrasonography. Serum high-sensitivity C-reactive protein (hs-CRP) levels were measured before and after treatment. Logistic analysis was applied to screen independent factors affecting treatment efficacy. Adverse reactions and life quality after 6 months of treatment were compared between the two groups. Results: The overall response rate of the observation group was higher than that of the control group (P<0.05). Changes in PAMP and PCWP in the two groups before and after treatment were significantly different. Patients in the observation group had improved indicators compared with the control group (all P<0.05). After treatment, the cardiac function indexes and inflammation-related factors of the observation group were improved more than those of the control group (P<0.05). Patients in the observation group had a lower incidence of adverse reactions and a higher life quality 6 months after treatment compared to the control group (P<0.05). Diabetes and treatment regimen were independent risk factors affecting treatment efficacy by logistic regression analysis. Conclusion: The administration of levosimendan helps improve cardiac function, hemodynamics, and body inflammation in patients with acute myocardial infarction and heart failure, with fewer adverse reactions and higher safety.
2023
true
true
true
false
false
GOLD
2023-11-14
false
http://www.ajtr.org
0
0
0
0
0
0
0
0
0
0
0
0
1
1
false
false
false
false
1
16
0
4
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
111811769
/api/authorship/111811769
1
0.25
true
false
false
Sun
Xiaoxia
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111811770
/api/authorship/111811770
2
0.25
false
false
false
Wei
Congying
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111811771
/api/authorship/111811771
3
0.25
false
false
false
Li
Lei
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111811772
/api/authorship/111811772
4
0.25
false
true
true
Qu
Chao
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
24838334
/api/publicationidentifier/24838334
IDENTICAL
001089038300007
https://www.webofscience.com/wos/woscc/full-record/001089038300007
false
true
Classification
12125
/api/classification/12125
true
true
Classification
12215
/api/classification/12215
true
true
Keyword
9926
/api/keyword/9926
true
9926
true
Keyword
14018
/api/keyword/14018
true
14018
true
Keyword
15324
/api/keyword/15324
true
15324
true
Keyword
1034973
/api/keyword/1034973
true
1034973
true
Keyword
1502150
/api/keyword/1502150
true
true
Keyword
3220543
/api/keyword/3220543
true
true
/api/publication/34323706
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Sun, Xiaoxia </span> <span class="author-type"> </span> ; <span class="author-name" > Wei, Congying </span> <span class="author-type"> </span> ; <span class="author-name" > Li, Lei </span> <span class="author-type"> </span> ; <span class="author-name" > Qu, Chao ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34323706" mtid="34323706" target="_blank">Levosimendan improves cardiac function, hemodynamics, and body inflammation in patients with acute myocardial infarction and heart failure</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-volume">15</span> : <span class="journal-issue">9</span> <span class="page"> pp. 5624-5632. , 9 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001089038300007" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001089038300007"> WoS </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34323706 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" >Sun Xiaoxia
</span>
;
<span class="author-name" >Wei Congying
</span>
;
<span class="author-name" >Li Lei
</span>
;
<span class="author-name" >Qu Chao ✉
</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34323706" target="_blank">Levosimendan improves cardiac function, hemodynamics, and body inflammation in patients with acute myocardial infarction and heart failure</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a>)</span>:
<span class="journal-volume">15</span> <span class="journal-issue">9</span>
<span class="page">
pp 5624-5632
</span> <span class="year">(2023)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Nyelv:
Angol
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="001089038300007" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001089038300007">
WoS
</a>
</span>
</span>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;34323706&sort=publishedYear,desc&sort=title">
Idézett közlemények száma: 1
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Közlemény: 34323706</span>
| <span class="status-data status-VALIDATED"> Egyeztetett
</span>
Idéző
| <span class="type-subtype">Folyóiratcikk
( Szakcikk
)
</span>
| <span class="pub-category">Tudományos</span>
| <span class="publication-sourceOfData">WoS-XML</span>
</div>
<div class="lastModified">Utolsó módosítás: 2023.11.14. 09:20 Szuper Admin (admin)
</div>
</div></div>
JournalArticle
34640715
VALIDATED
true
0
false
2024-02-20T06:51:41.280+0000
2024-02-20T06:50:26.763+0000
2024-02-20T06:50:25.997+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
2024-02-22T01:51:00.222+0000
2024-02-20T06:50:26.072+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
false
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Yang, Jinjing
PCSK9 inhibitors suppress oxidative stress and inflammation in atherosclerotic development by promoting macrophage autophagy
true
true
/api/journal/10032933
REVIEWED
true
false
10032933
false
10032933
true
1943-8141
1943-8141
Journal
FOREIGN
15
8
5129
+
5129
17
2023
2024
true
true
true
false
false
GOLD
2024-02-20
false
http://www.ajtr.org
0
0
0
0
0
0
0
0
0
0
0
0
1
1
false
false
false
false
2
15
0
8
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
114917057
/api/authorship/114917057
1
0.125
true
false
false
Yang
Jinjing
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114917058
/api/authorship/114917058
2
0.125
false
false
false
Ma
Xiurui
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114917059
/api/authorship/114917059
3
0.125
false
false
false
Niu
Dan
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114917060
/api/authorship/114917060
4
0.125
false
false
false
Sun
Yu
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114917061
/api/authorship/114917061
5
0.125
false
false
false
Chai
Xiaohong
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114917062
/api/authorship/114917062
6
0.125
false
false
false
Deng
Yongzhi
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114917063
/api/authorship/114917063
7
0.125
false
false
true
Wang
Jingping
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114917064
/api/authorship/114917064
8
0.125
false
true
true
Dong
Jin
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
25626397
/api/publicationidentifier/25626397
IDENTICAL
001096985200012
https://www.webofscience.com/wos/woscc/full-record/001096985200012
false
true
Classification
12125
/api/classification/12125
true
true
Classification
12215
/api/classification/12215
true
true
Keyword
64
/api/keyword/64
true
64
true
Keyword
308
/api/keyword/308
true
308
true
Keyword
1027167
/api/keyword/1027167
true
1027167
true
Keyword
1716411
/api/keyword/1716411
true
true
Keyword
2014641
/api/keyword/2014641
true
true
/api/publication/34640715
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Yang, Jinjing </span> <span class="author-type"> </span> ; <span class="author-name" > Ma, Xiurui </span> <span class="author-type"> </span> ; <span class="author-name" > Niu, Dan </span> <span class="author-type"> </span> ; <span class="author-name" > Sun, Yu </span> <span class="author-type"> </span> ; <span class="author-name" > Chai, Xiaohong </span> <span class="author-type"> </span> ; <span class="author-name" > Deng, Yongzhi </span> <span class="author-type"> </span> ; <span class="author-name" > Wang, Jingping ✉ </span> <span class="author-type"> </span> ; <span class="author-name" > Dong, Jin ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34640715" mtid="34640715" target="_blank">PCSK9 inhibitors suppress oxidative stress and inflammation in atherosclerotic development by promoting macrophage autophagy</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-volume">15</span> : <span class="journal-issue">8</span> <span class="page"> pp. 5129-+. , 17 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001096985200012" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001096985200012"> WoS </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34640715 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" >Yang Jinjing
</span>
;
<span class="author-name" >Ma Xiurui
</span>
;
<span class="author-name" >Niu Dan
</span>
;
<span class="author-name" >Sun Yu
</span>
;
<span class="author-name" >Chai Xiaohong
</span>
;
<span class="author-name" >Deng Yongzhi
</span>
;
<span class="author-name" >Wang Jingping ✉
</span>
;
<span class="author-name" >Dong Jin ✉
</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34640715" target="_blank">PCSK9 inhibitors suppress oxidative stress and inflammation in atherosclerotic development by promoting macrophage autophagy</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a>)</span>:
<span class="journal-volume">15</span> <span class="journal-issue">8</span>
<span class="page">
pp 5129-+
</span> <span class="year">(2023)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Nyelv:
Angol
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="001096985200012" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001096985200012">
WoS
</a>
</span>
</span>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;34640715&sort=publishedYear,desc&sort=title">
Idézett közlemények száma: 1
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Közlemény: 34640715</span>
| <span class="status-data status-VALIDATED"> Egyeztetett
</span>
Idéző
| <span class="type-subtype">Folyóiratcikk
( Szakcikk
)
</span>
| <span class="pub-category">Tudományos</span>
| <span class="publication-sourceOfData">WoS-XML</span>
</div>
<div class="lastModified">Utolsó módosítás: 2024.02.20. 07:50 Szuper Admin (admin)
</div>
</div></div>
JournalArticle
34592257
VALIDATED
true
0
false
2024-02-15T16:48:18.784+0000
2024-02-15T16:47:08.212+0000
2024-02-15T16:47:07.253+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
2024-02-15T16:47:07.065+0000
2024-02-15T16:47:07.065+0000
2024-02-15T16:47:07.344+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
false
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Zhang, Jun
Particulate matter promotes the epithelial to mesenchymal transition in human lung epithelial cells via the ROS pathway
true
true
/api/journal/10032933
REVIEWED
true
false
10032933
false
10032933
true
1943-8141
1943-8141
Journal
FOREIGN
15
8
5159
+
5159
11
2023
Objects: Epidemiologic studies have linked exposure to airborne pollutant particulate matter (PM) with increased rates of chronic cardiopulmonary diseases, including asthma and idiopathic pulmonary fibrosis (IPF). Several investigations have suggested that the epithelial-to-mesenchymal transition (EMT) may contribute to the complex pathobiology of environmental exposure-mediated pulmonary fibrosis. The present study was designed to characterize the mechanisms of PM-mediated EMT in human lung epithelial cells (HBECs). Methods and results: PM induced significant dose (0-100 mu g/ml) and time (0-72 h)-dependent increases in transforming growth factor beta (TGF beta) and fibronectin (FN) protein levels in HBECs lysates. PM-activated TGF beta and FN protein production in HBECs was prevented by the antioxidant N-acetyl-cysteine (NAC, 5 mM). Furthermore, the NF-KB inhibitor BAY11-7082 (5 mu M) abolished PM-induced FN production in HBECs. Biomarkers of EMT (ACTA2, SNAIL1 and SNAIL2) in PM-treated HBECs were significantly increased at the mRNA level compared to control cells. Conclusions: These results demonstrate that PM increases protein levels of TGF beta and FN via reactive oxygen species (ROS)-dependent pathways. In addition, PM exposure induces EMT in human lung epithelial cells, supporting a novel mechanism for PM-induced pulmonary fibrosis.
2024
true
true
true
false
false
GOLD
2024-02-15
false
http://www.ajtr.org
0
0
0
0
0
0
0
0
0
0
0
0
1
1
false
false
false
false
1
5
0
7
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
114511677
/api/authorship/114511677
1
0.14285715
true
false
false
Zhang
Jun
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114511678
/api/authorship/114511678
2
0.14285715
false
false
false
Xu
Xiaoyan
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114511679
/api/authorship/114511679
3
0.14285715
false
false
false
Liang
Ying
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114511680
/api/authorship/114511680
4
0.14285715
false
false
false
Wu
Xiaomin
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114511681
/api/authorship/114511681
5
0.14285715
false
false
false
Qian
Zhongqing
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114511682
/api/authorship/114511682
6
0.14285715
false
false
true
Zhang
Liming
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
114511683
/api/authorship/114511683
7
0.14285715
false
true
true
Wang
Ting
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
25517792
/api/publicationidentifier/25517792
IDENTICAL
001096985200014
https://www.webofscience.com/wos/woscc/full-record/001096985200014
false
true
Classification
12125
/api/classification/12125
true
true
Classification
12215
/api/classification/12215
true
true
Keyword
3353
/api/keyword/3353
true
3353
true
Keyword
15242
/api/keyword/15242
true
15242
true
Keyword
1057995
/api/keyword/1057995
true
1057995
true
Keyword
1576492
/api/keyword/1576492
true
true
/api/publication/34592257
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Zhang, Jun </span> <span class="author-type"> </span> ; <span class="author-name" > Xu, Xiaoyan </span> <span class="author-type"> </span> ; <span class="author-name" > Liang, Ying </span> <span class="author-type"> </span> ; <span class="author-name" > Wu, Xiaomin </span> <span class="author-type"> </span> ; <span class="author-name" > Qian, Zhongqing </span> <span class="author-type"> </span> ; <span class="author-name" > Zhang, Liming ✉ </span> <span class="author-type"> </span> ; <span class="author-name" > Wang, Ting ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34592257" mtid="34592257" target="_blank">Particulate matter promotes the epithelial to mesenchymal transition in human lung epithelial cells via the ROS pathway</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-volume">15</span> : <span class="journal-issue">8</span> <span class="page"> pp. 5159-+. , 11 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001096985200014" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001096985200014"> WoS </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34592257 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" >Zhang Jun
</span>
;
<span class="author-name" >Xu Xiaoyan
</span>
;
<span class="author-name" >Liang Ying
</span>
;
<span class="author-name" >Wu Xiaomin
</span>
;
<span class="author-name" >Qian Zhongqing
</span>
;
<span class="author-name" >Zhang Liming ✉
</span>
;
<span class="author-name" >Wang Ting ✉
</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34592257" target="_blank">Particulate matter promotes the epithelial to mesenchymal transition in human lung epithelial cells via the ROS pathway</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a>)</span>:
<span class="journal-volume">15</span> <span class="journal-issue">8</span>
<span class="page">
pp 5159-+
</span> <span class="year">(2023)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Nyelv:
Angol
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="001096985200014" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001096985200014">
WoS
</a>
</span>
</span>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;34592257&sort=publishedYear,desc&sort=title">
Idézett közlemények száma: 1
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Közlemény: 34592257</span>
| <span class="status-data status-VALIDATED"> Egyeztetett
</span>
Idéző
| <span class="type-subtype">Folyóiratcikk
( Szakcikk
)
</span>
| <span class="pub-category">Tudományos</span>
| <span class="publication-sourceOfData">WoS-XML</span>
</div>
<div class="lastModified">Utolsó módosítás: 2024.02.15. 17:47 Szuper Admin (admin)
</div>
</div></div>
JournalArticle
34503769
APPROVED
true
0
false
2024-01-15T13:29:59.429+0000
2024-01-15T13:17:34.315+0000
2024-01-15T13:14:13.075+0000
true
10024397
Szabó
Katalin
/api/admin/10024397
Admin
true
10024397
2024-01-15T13:17:34.633+0000
2024-01-15T13:17:34.633+0000
false
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Wei, Shanzhai
Safety and effectiveness of recombinant human erythropoietin coupled with different doses of Roxadustat for treatment of renal anemia in patients on maintenance hemodialysis
true
true
/api/journal/10032933
REVIEWED
true
false
10032933
false
10032933
true
1943-8141
1943-8141
Journal
FOREIGN
15
8
5120
5128
5120
9
2023
Objective: To investigate the safety and efficacy of recombinant human erythropoietin (rHuEPO) in com-bination with different doses of Roxadustat in treating renal anemia in patients on maintenance hemodialysis. Methods: Eighty patients with renal anemia on maintenance hemodialysis treated in Shuyang Hospital of Traditional Chinese Medicine from January 2020 to December 2021 were selected as study subjects, and they were divided into a study group (n=40, high-dose Roxadustat + rHuEPO therapy) and a control group (Con) (n=40, low-dose Roxadustat + rHuEPO therapy) in accordance with different therapies. The effects of anemia therapy, changes in anemia indicators (hemoglobin (Hb), hematocrit (Hct)), changes in iron metabolism indicators (transferrin saturation (TSAT), serum ferritin (SF)), changes in oxidative stress indicators Malondialdehyde (MDA), Superoxide Dismutase (SOD), and changes in microinflammatory indicators IL6, CRP were compared between the two groups. The occur-rences of adverse effects during therapy were counted and compared between the two groups. Results: The therapy efficiency of the study group was 97.50% (39/40), which was higher than 85.00% (34/40) in the control group (P=0.048). The contents of Hb, Hct, TSAT, and SF were higher in the study group than the Con after therapy (all P<0.001 or P=0.001). The contents of MDA, IL6, and CRP were significantly lower in the study group than the Con after therapy (all P<0.001). The occurrence of adverse effects was 10.00% in the study group, which was higher than 5.00% in the Con, but the difference was not significant (P=0.396). Conclusion: The combination of rHuEPO and high-dose Roxadustat (120 mg/time) has a better effect on improving anemia symptoms in maintenance he-modialysis patients than in those who take low dose Roxadustat (100 mg/time). It can significantly improve anemia and iron metabolism indicators and alleviate patients' inflammation and oxidative stress levels.
2024
true
true
true
false
false
GOLD
2024-01-15
false
http://www.ajtr.org
0
0
0
0
0
0
0
0
0
0
0
0
1
1
false
false
false
false
2024-04-14T12:17:34.180+0000
1
6
0
5
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
113876568
/api/authorship/113876568
1
0.2
true
false
false
Wei
Shanzhai
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113876569
/api/authorship/113876569
2
0.2
false
false
false
Sun
Jie
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113876570
/api/authorship/113876570
3
0.2
false
false
false
Xu
Kangchun
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113876571
/api/authorship/113876571
4
0.2
false
false
false
Li
Yibei
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
113876572
/api/authorship/113876572
5
0.2
false
true
true
Zhang
Yilai
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
25292145
/api/publicationidentifier/25292145
001096985200011
https://www.webofscience.com/wos/woscc/full-record/001096985200011
false
true
PublicationIdentifier
25292146
/api/publicationidentifier/25292146
37692953
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37692953&dopt=Abstract
false
true
Keyword
17193
/api/keyword/17193
true
17193
true
Keyword
1100778
/api/keyword/1100778
true
1100778
true
Keyword
1114898
/api/keyword/1114898
true
1114898
true
Keyword
1497913
/api/keyword/1497913
true
true
Keyword
1646853
/api/keyword/1646853
true
true
Keyword
1762869
/api/keyword/1762869
true
true
Keyword
1841110
/api/keyword/1841110
true
true
Keyword
2192145
/api/keyword/2192145
true
true
Keyword
2728384
/api/keyword/2728384
true
true
/api/publication/34503769
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Wei, Shanzhai </span> <span class="author-type"> </span> ; <span class="author-name" > Sun, Jie </span> <span class="author-type"> </span> ; <span class="author-name" > Xu, Kangchun </span> <span class="author-type"> </span> ; <span class="author-name" > Li, Yibei </span> <span class="author-type"> </span> ; <span class="author-name" > Zhang, Yilai ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34503769" mtid="34503769" target="_blank">Safety and effectiveness of recombinant human erythropoietin coupled with different doses of Roxadustat for treatment of renal anemia in patients on maintenance hemodialysis</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-volume">15</span> : <span class="journal-issue">8</span> <span class="page"> pp. 5120-5128. , 9 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="001096985200011" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001096985200011"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="37692953" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37692953&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34503769 </span> <span class="status-holder"><span class="status-data status-APPROVED"> Nyilvános </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Wei Shanzhai </span> ; <span class="author-name" >Sun Jie </span> ; <span class="author-name" >Xu Kangchun </span> ; <span class="author-name" >Li Yibei </span> ; <span class="author-name" >Zhang Yilai ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;34503769" target="_blank">Safety and effectiveness of recombinant human erythropoietin coupled with different doses of Roxadustat for treatment of renal anemia in patients on maintenance hemodialysis</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a>)</span>: <span class="journal-volume">15</span> <span class="journal-issue">8</span> <span class="page"> pp 5120-5128 </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="001096985200011" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001096985200011"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="37692953" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37692953&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34503769&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34503769</span> | <span class="status-data status-APPROVED"> Nyilvános </span> Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Utolsó módosítás: 2024.01.15. 14:17 Szabó Katalin (PTE ETK admin 6) </div> </div></div>
JournalArticle
34366804
VALIDATED
true
0
false
2023-11-19T10:03:32.485+0000
2023-11-19T09:59:31.289+0000
2023-11-19T09:59:30.440+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
4781792
2024-02-22T07:33:38.151+0000
2024-02-22T07:33:37.964+0000
Admin
521
/api/admin/521
Szuper
Admin
true
true
SUSPECT
2023-11-19T09:59:30.263+0000
2024-02-22T07:33:37.964+0000
2023-11-19T09:59:30.498+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
false
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Xie, Ting
Down-regulation of Jun induces senescence through destabilizing chromatin in osteoarthritis chondrocytes
true
true
/api/journal/10032933
REVIEWED
true
false
10032933
false
10032933
true
1943-8141
1943-8141
Journal
FOREIGN
15
7
4873
+
4873
15
2023
Objective: Osteoarthritis (OA) is the most common degenerative joint disease leading to disability worldwide. Cellular senescence is considered to be a fundamental pathogenic mechanism in the development of OA and has attracted increasing attention. However, regulatory mechanisms underlying chondrocyte senescence in OA remain unclear. Methods: Bioinformatic methods were used to screen key genes. Immunohistochemistry and the quantitative reverse transcription polymerase chain reaction were used to evaluate gene expression. RNA intervention experiments were performed to explore the functions of key genes. Results: We used 494 aging-associated genes provided by the Aging Atlas to identify the co-expression modules associated with age and OA. Thirty age-associated differentially expressed genes (ASDEGs) were identified. Using cytoHubba in Cytoscape, we identified Jun as the hub-ASDEG for OA chondrocytes. We confirmed the downregulation of Jun in OA rats and senescent chondrocytes by immunohistochemistry and quantitative reverse transcription polymerase chain reaction, respectively. Inhibition of proliferation and accelerated senescence were observed in chondrocytes treated with siRNA against Jun. Mechanistically, we observed micronuclei formation and reduced expression of H3K9me3 and heterochromatin protein 1gamma in siRNA-Jun-treated chondrocytes, indicating that destabilization of chromatin occurred during this treatment. Conclusion: Jun plays a crucial role in OA development and causes senescence by destabilizing chromatin in chondrocytes. These findings provide new insights into OA progression and suggest promising therapeutic targets.
2023
true
true
true
false
false
GOLD
2023-11-19
false
http://www.ajtr.org
0
0
0
0
0
0
0
0
0
0
0
0
1
1
false
false
false
false
1
1
0
6
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
112160987
/api/authorship/112160987
1
0.16666667
true
false
false
Xie
Ting
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
112160988
/api/authorship/112160988
2
0.16666667
false
false
false
Ren
Xunshan
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
112160989
/api/authorship/112160989
3
0.16666667
false
false
false
Zhuang
Huangming
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
112160990
/api/authorship/112160990
4
0.16666667
false
false
false
Jiang
Fuze
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
112160991
/api/authorship/112160991
5
0.16666667
false
false
false
Zhang
Yuelong
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
112160992
/api/authorship/112160992
6
0.16666667
false
true
true
Zhou
Panghu
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
24945899
/api/publicationidentifier/24945899
IDENTICAL
001048895000002
https://www.webofscience.com/wos/woscc/full-record/001048895000002
false
true
Classification
12125
/api/classification/12125
true
true
Classification
12215
/api/classification/12215
true
true
Keyword
1014859
/api/keyword/1014859
true
1014859
true
Keyword
1036266
/api/keyword/1036266
true
1036266
true
Keyword
1119321
/api/keyword/1119321
true
1119321
true
Keyword
1310319
/api/keyword/1310319
true
1310319
true
/api/publication/34366804
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Xie, Ting </span> <span class="author-type"> </span> ; <span class="author-name" > Ren, Xunshan </span> <span class="author-type"> </span> ; <span class="author-name" > Zhuang, Huangming </span> <span class="author-type"> </span> ; <span class="author-name" > Jiang, Fuze </span> <span class="author-type"> </span> ; <span class="author-name" > Zhang, Yuelong </span> <span class="author-type"> </span> ; <span class="author-name" > Zhou, Panghu ✉ </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34366804" mtid="34366804" target="_blank">Down-regulation of Jun induces senescence through destabilizing chromatin in osteoarthritis chondrocytes</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-volume">15</span> : <span class="journal-issue">7</span> <span class="page"> pp. 4873-+. , 15 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001048895000002" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001048895000002"> WoS </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34366804 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" >Xie Ting
</span>
;
<span class="author-name" >Ren Xunshan
</span>
;
<span class="author-name" >Zhuang Huangming
</span>
;
<span class="author-name" >Jiang Fuze
</span>
;
<span class="author-name" >Zhang Yuelong
</span>
;
<span class="author-name" >Zhou Panghu ✉
</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34366804" target="_blank">Down-regulation of Jun induces senescence through destabilizing chromatin in osteoarthritis chondrocytes</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a>)</span>:
<span class="journal-volume">15</span> <span class="journal-issue">7</span>
<span class="page">
pp 4873-+
</span> <span class="year">(2023)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Nyelv:
Angol
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="001048895000002" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001048895000002">
WoS
</a>
</span>
</span>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;34366804&sort=publishedYear,desc&sort=title">
Idézett közlemények száma: 1
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Közlemény: 34366804</span>
| <span class="status-data status-VALIDATED"> Egyeztetett
</span>
Idéző
| <span class="type-subtype">Folyóiratcikk
( Szakcikk
)
</span>
| <span class="pub-category">Tudományos</span>
| <span class="publication-sourceOfData">WoS-XML</span>
</div>
<div class="lastModified">Utolsó módosítás: 2023.11.19. 10:59 Szuper Admin (admin)
</div>
</div></div>
JournalArticle
34342403
VALIDATED
true
0
false
2023-11-16T08:57:18.530+0000
2023-11-16T08:53:11.429+0000
2023-11-16T08:53:08.050+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
2023-11-16T08:53:07.863+0000
2023-11-16T08:53:07.863+0000
2023-11-16T08:53:08.227+0000
true
521
Szuper
Admin
/api/admin/521
Admin
true
false
false
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
true
10000059
Article
true
24
24
/api/publicationtype/24
PublicationType
1
true
24
JournalArticle
/api/subtype/10000059
Szakcikk
SubType
101
true
10000059
true
1
/api/category/1
Category
true
1
Ali, Liaqat
In vitro analysis of PI3K pathway activation genes for exploring novel biomarkers and therapeutic targets in clear cell renal carcinoma
true
true
/api/journal/10032933
REVIEWED
true
false
10032933
false
10032933
true
1943-8141
1943-8141
Journal
FOREIGN
15
7
4851
4872
4851
22
2023
Objectives: The regulation of various cellular functions such as growth, proliferation, metabolism, and angiogenesis, is dependent on the PI3K pathway. Recent evidence has indicated that kidney renal clear cell carcinoma (KIRC) can be triggered by the deregulation of this pathway. The objective of this research was to investigate 25 genes associated with activation of the PI3K pathway in KIRC and control samples to identify four hub genes that might serve as novel molecular biomarkers and therapeutic targets for treating KIRC. Methods: Multi-omics in silico and in vitro analysis was employed to find hub genes related to the PI3K pathway that may be biomarkers and therapeutic targets for KIRC. Results: Using STRING software, a protein-protein interaction (PPI) network of 25 PI3K pathway-related genes was developed. Based on the degree scoring method, the top four hub genes were identified using Cytoscape's Cytohubba plug-in. TCGA datasets, KIRC (786-O and A-498), and normal (HK2) cells were used to validate the expression of hub genes. Additionally, further bioinformatic analyses were performed to investigate the mechanisms by which hub genes are involved in the development of KIRC. Out of a total of 25 PI3K pathway-related genes, we developed and validated a diagnostic and prognostic model based on the up-regulation of TP53 (tumor protein 53) and CCND1 (Cyclin D1) and the down-regulation of PTEN (Phosphatase and TENsin homolog deleted on chromosome 10), and GSK3B (Glycogen synthase kinase-3 beta) hub genes. The hub genes included in our model may be a novel therapeutic target for KIRC treatment. Additionally, associations between hub genes and infiltration of immune cells can enhance comprehension of immunotherapy for KIRC. Conclusion: We have created a new diagnostic and prognostic model for KIRC patients that uses PI3K pathway-related hub genes (TP53, PTEN, CCND1, and GSK3B). Nevertheless, further experimental studies are required to ascertain the efficacy of our model.
2023
true
true
true
false
false
GOLD
2023-11-16
false
http://www.ajtr.org
0
0
0
0
0
0
0
0
0
0
0
0
1
1
false
false
false
false
2
20
0
14
0
true
Language
10002
/api/language/10002
Angol
English
true
2
true
PersonAuthorship
111970247
/api/authorship/111970247
1
0.071428575
true
false
false
Ali
Liaqat
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970248
/api/authorship/111970248
2
0.071428575
false
false
true
Raza
Abbas Ali
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970249
/api/authorship/111970249
3
0.071428575
false
false
false
Bin Zaheer
Ahmad
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970250
/api/authorship/111970250
4
0.071428575
false
false
false
Alhomrani
Majid
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970251
/api/authorship/111970251
5
0.071428575
false
false
false
Alamri
Abdulhakeem S.
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970252
/api/authorship/111970252
6
0.071428575
false
false
false
Alghamdi
Saleh A.
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970253
/api/authorship/111970253
7
0.071428575
false
false
false
Almalki
Abdulraheem Ali
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970254
/api/authorship/111970254
8
0.071428575
false
false
false
Alghamdi
Ahmad A.
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970255
/api/authorship/111970255
9
0.071428575
false
false
false
Khawaja
Imran
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970256
/api/authorship/111970256
10
0.071428575
false
false
false
Alhadrami
Mai
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970257
/api/authorship/111970257
11
0.071428575
false
false
false
Ramzan
Faiqah
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970258
/api/authorship/111970258
12
0.071428575
false
false
true
Jamil
Muhammad
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970259
/api/authorship/111970259
13
0.071428575
false
false
false
Ali
Mubarik
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PersonAuthorship
111970260
/api/authorship/111970260
14
0.071428575
false
true
false
Jabeen
Norina
true
false
false
AuthorshipType
1
/api/authorshiptype/1
0
true
0
true
false
true
PublicationIdentifier
24890497
/api/publicationidentifier/24890497
IDENTICAL
001048895000001
https://www.webofscience.com/wos/woscc/full-record/001048895000001
false
true
Classification
12125
/api/classification/12125
true
true
Classification
12215
/api/classification/12215
true
true
Keyword
14256
/api/keyword/14256
true
14256
true
Keyword
1004566
/api/keyword/1004566
true
1004566
true
Keyword
1458872
/api/keyword/1458872
true
1458872
true
Keyword
1766635
/api/keyword/1766635
true
true
/api/publication/34342403
<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" > Ali, Liaqat </span> <span class="author-type"> </span> ; <span class="author-name" > Raza, Abbas Ali ✉ </span> <span class="author-type"> </span> ; <span class="author-name" > Bin Zaheer, Ahmad </span> <span class="author-type"> </span> ; <span class="author-name" > Alhomrani, Majid </span> <span class="author-type"> </span> ; <span class="author-name" > Alamri, Abdulhakeem S. </span> <span class="author-type"> </span> ; <span class="author-name" > Alghamdi, Saleh A. </span> <span class="author-type"> </span> ; <span class="author-name" > Almalki, Abdulraheem Ali </span> <span class="author-type"> </span> ; <span class="author-name" > Alghamdi, Ahmad A. </span> <span class="author-type"> </span> ; <span class="author-name" > Khawaja, Imran </span> <span class="author-type"> </span> ; <span class="author-name" > Alhadrami, Mai </span> <span class="author-type"> </span> et al. </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;34342403" mtid="34342403" target="_blank">In vitro analysis of PI3K pathway activation genes for exploring novel biomarkers and therapeutic targets in clear cell renal carcinoma</a></div> <div class="pub-info"> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span> <span class="journal-volume">15</span> : <span class="journal-issue">7</span> <span class="page"> pp. 4851-4872. , 22 p. </span> <span class="year">(2023)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001048895000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001048895000001"> WoS </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="short-pub-mtid"> Közlemény:34342403 </span> <span class="status-holder"><span class="status-data status-VALIDATED"> Egyeztetett </span></span> <span class="pub-core"> Idéző </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> </div> </div> </div><div class="JournalArticle Publication long-list">
<div class="authors">
<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png">
<div class="autype autype0"> <span class="author-name" >Ali Liaqat
</span>
;
<span class="author-name" >Raza Abbas Ali ✉
</span>
;
<span class="author-name" >Bin Zaheer Ahmad
</span>
;
<span class="author-name" >Alhomrani Majid
</span>
;
<span class="author-name" >Alamri Abdulhakeem S.
</span>
;
<span class="author-name" >Alghamdi Saleh A.
</span>
;
<span class="author-name" >Almalki Abdulraheem Ali
</span>
;
<span class="author-name" >Alghamdi Ahmad A.
</span>
;
<span class="author-name" >Khawaja Imran
</span>
;
<span class="author-name" >Alhadrami Mai
</span>
;
<span class="author-name" >Ramzan Faiqah
</span>
;
<span class="author-name" >Jamil Muhammad ✉
</span>
;
<span class="author-name" >Ali Mubarik
</span>
;
<span class="author-name" >Jabeen Norina
</span>
</div>
</div>
<div class="title"><a href="/gui2/?mode=browse¶ms=publication;34342403" target="_blank">In vitro analysis of PI3K pathway activation genes for exploring novel biomarkers and therapeutic targets in clear cell renal carcinoma</a></div> <div> <span class="journal-title">AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH</span>
<span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1943-8141">1943-8141</a>)</span>:
<span class="journal-volume">15</span> <span class="journal-issue">7</span>
<span class="page">
pp 4851-4872
</span> <span class="year">(2023)</span>
</div>
<div class="pub-footer">
<span class="language" xmlns="http://www.w3.org/1999/html">Nyelv:
Angol
| </span>
<span class="identifiers">
<span class="id identifier oa_none" title="none">
<a style="color:blue" title="001048895000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001048895000001">
WoS
</a>
</span>
</span>
<div class="publication-citation">
<a target="_blank" href="/api/publication?cond=citations.related;eq;34342403&sort=publishedYear,desc&sort=title">
Idézett közlemények száma: 1
</a>
</div>
<div class="mtid"><span class="long-pub-mtid">Közlemény: 34342403</span>
| <span class="status-data status-VALIDATED"> Egyeztetett
</span>
Idéző
| <span class="type-subtype">Folyóiratcikk
( Szakcikk
)
</span>
| <span class="pub-category">Tudományos</span>
| <span class="publication-sourceOfData">WoS-XML</span>
</div>
<div class="lastModified">Utolsó módosítás: 2023.11.16. 09:53 Szuper Admin (admin)
</div>
</div></div>