@article{MTMT:36710206,
	title = {Iron, the Essential Micronutrient: A Comprehensive Review of Regulatory Pathways of Iron Metabolism},
	url = {https://m2.mtmt.hu/api/publication/36710206},
	author = {Horváth, Adrienn and Tamási, Kitti and Pap, Ramóna and Jánosa, Gergely and Pandur, Edina},
	doi = {10.3390/nu18010109},
	journal-iso = {NUTRIENTS},
	journal = {NUTRIENTS},
	volume = {18},
	unique-id = {36710206},
	abstract = {Iron constitutes an essential micronutrient in living organisms. All iron is absorbed into the body through dietary intake, except for exogenous therapeutic sources. Dietary iron is typically categorized as either heme or nonheme iron. Nonheme iron is essential for regulating iron in the body, as it exists in various forms, including soluble iron, storage iron within ferritin, and iron found in the catalytic centers of a wide range of proteins. Iron homeostasis is carefully managed to ensure that sufficient iron is available for critical biological processes while preventing the harmful effects that can arise from excess iron. The small peptide hormone hepcidin is the main regulator of iron homeostasis. Hepcidin and other iron regulatory molecules are regulated by various signaling pathways, such as IL-6/JAK-STAT, BMP/SMAD, and MAPK. Alterations in regulatory pathways may occur in response to iron accumulation or deficiency. Iron overload in the body can activate JAK/STAT, BMP/SMAD and MAPK pathways, leading to the initiation hepcidin synthesis. Conversely, in iron deficiency, as in hypoxic conditions or EPO-mediated signaling pathways, HAMP synthesis in the nucleus is reduced. Thus, this review provides an update on the possible regulatory pathways that play a role in iron regulation and may be potential therapeutic targets.},
	keywords = {IRON; HEPCIDIN; Regulatory pathway; JAK-STAT; HAMP; BMP/SMAD},
	year = {2026},
	eissn = {2072-6643},
	orcid-numbers = {Pap, Ramóna/0000-0002-3340-0102; Jánosa, Gergely/0000-0001-5374-6680; Pandur, Edina/0000-0001-5012-3242}
}

@article{MTMT:37521433,
	title = {Dietary Bioactive Compounds: Cellular Sensory Pathways, Microbial Partners, and Clinical Realities},
	url = {https://m2.mtmt.hu/api/publication/37521433},
	author = {Elandia, Aparecida and dos, Santos and Jacqueline, Isaura Alvarez-Leite},
	doi = {10.3390/nu18183001},
	journal-iso = {NUTRIENTS},
	journal = {NUTRIENTS},
	unique-id = {37521433},
	year = {2026},
	eissn = {2072-6643}
}

@article{MTMT:37102039,
	title = {Maternal Diet, Lifestyle Factors, and Gestational Weight Gain: A Single-Center Case–Control Study in Hungary},
	url = {https://m2.mtmt.hu/api/publication/37102039},
	author = {Paulik, Edit and Sisák, Anita and Szolnoki, Anna and Polanek, Evelin and Gajdács, Márió and Molnár, Regina and Szabó, Andrea and Németh, Gábor László and Orvos, Hajnalka},
	doi = {10.3390/nu18091403},
	journal-iso = {NUTRIENTS},
	journal = {NUTRIENTS},
	volume = {18},
	unique-id = {37102039},
	abstract = {Background/Objectives: Preterm birth (PTB) is a major public health concern worldwide, which may lead to detrimental maternal and neonatal outcomes. Maternal nutritional status, gestational weight gain (GWG), and lifestyle factors are potentially modifiable determinants of adverse pregnancy outcomes. This study examined the association between PTB and maternal GWG and assessed whether maternal dietary habits and lifestyle factors were related to GWG in women delivering preterm versus at term. Methods: A retrospective case–control study was conducted at a tertiary center in Hungary (MANOR Study, 2019). The case group included n = 100 women with PTB, while n = 200 matched term deliveries served as controls (1:2 ratio). Data were collected using a self-administered questionnaire and medical records. Pre-pregnancy body mass index (BMI) was categorized using standard definitions, while GWG was classified as inadequate, recommended, or excessive according to the US 2009 Institute of Medicine guidelines. A 7-item dietary index score was calculated based on gestational dietary habits. Results: Pre-pregnancy BMI distribution did not considerably differ between groups (p > 0.05); over one-third of women in both groups were overweight or had obesity (38.7% vs. 36.7%). Previous PTB (p < 0.001) and gestational hypertension (GHT) (p = 0.003) were more common among current PTB cases, while smoking, alcohol consumption, and gestational diabetes mellitus (GDM) showed negligible differences (p > 0.05)—28.0% of cases, and 34.5% of controls were classified as having healthy dietary habits, based on the dietary index score calculated. Inadequate GWG was more prevalent among PTB cases (49.0% vs. 26.8%), whereas excessive GWG was less frequent among cases (21.9% vs. 38.4%). Being within the recommended GWG range and the manifestation of gestational hypertension were associated with lower (aOR: 0.39; 95% CI: 0.18–0.87; p = 0.020) and higher (aOR: 3.43; 95% CI: 1.44–8.19; p = 0.005) odds of PTB, respectively. Conclusions: Inadequate GWG was more common in PTB, while excessive GWG was more frequent in term pregnancies. Fast-food consumption was associated with excessive GWG among term births. Optimizing GWG and improving maternal diet quality should be included as key, cross-cutting interventions targeting the improvement of antenatal care.},
	year = {2026},
	eissn = {2072-6643},
	orcid-numbers = {Paulik, Edit/0000-0002-3446-4327; Sisák, Anita/0000-0002-3661-6670; Polanek, Evelin/0000-0002-9829-0821; Gajdács, Márió/0000-0003-1270-0365; Szabó, Andrea/0000-0003-4949-9431; Németh, Gábor László/0000-0003-1829-3457; Orvos, Hajnalka/0000-0001-9400-865X}
}

@article{MTMT:37102317,
	title = {Optimizing Public Health Screening: Population-Specific BMI Thresholds for Targeted Body Composition Assessment in Hungary},
	url = {https://m2.mtmt.hu/api/publication/37102317},
	author = {Jarecsny, Tamás and Al-Muhanna, Nadim and Fábián, Dóra Rebeka and Kosik, Roland and Schwab, Richard and Szőllősi, Gergő József and Schandl, László and Tomasics, Gyula and Pázmándi, Eszter Melinda and Folyovich, András and Fazekas, Ferenc and Fekete, Mónika},
	doi = {10.3390/nu18091410},
	journal-iso = {NUTRIENTS},
	journal = {NUTRIENTS},
	volume = {18},
	unique-id = {37102317},
	abstract = {Background: Body mass index (BMI) is widely used as a proxy of nutritional status and related lifestyle risk patterns in public health, yet it does not capture body composition–related heterogeneity in cardiometabolic risk. Evidence on whether a more detailed body composition assessment improves population-level screening efficiency remains inconsistent, particularly in Central European populations. Methods: We conducted a cross-sectional analysis of 868 Hungarian adults participating in a nationwide mobile screening program. Locally weighted regression identified sex-specific BMI inflection points for cardiometabolic risk. Stratified receiver operating characteristic (ROC) analyses compared BMI with bioelectrical impedance-derived parameters across five outcomes. Cost- and time-effectiveness of scalable screening strategies were modeled at the population level. Results: Cardiometabolic risk increased at BMI levels below current WHO thresholds (females: 21.8–22.3 kg/m2; males: 23.8–24.3 kg/m2). Overall, body composition parameters did not outperform BMI in the full population. Subgroup-specific differences were observed, particularly among men with BMI 24–36 kg/m2 for atherosclerosis risk, suggesting limited and outcome-specific added value rather than broad superiority over BMI. Together, non-linear risk patterns, stratified performance, and population-level modeling converged on mid-range BMI intervals (females: 22–30 kg/m2; males: 24–30 kg/m2) as likely screening windows of phenotypic heterogeneity. Within these ranges, targeted InBody assessment may help refine risk assessment for selected individuals. A mixed screening strategy covering 52% of the population would cost 178.4% of BMI-only screening, while reducing throughput by 24.3%. Conclusions: Population-specific BMI thresholds may more accurately reflect early deviations in nutritional and cardiometabolic risk than current universal cutoffs. BMI remains a useful first-line marker, and body composition assessment may add complementary information in selected BMI ranges. Overall, these findings support a potentially useful, subgroup-specific screening approach, but the modeled cost and time trade-offs should be considered hypothesis-generating and require further validation.},
	keywords = {Body Mass Index; body composition; Nutritional Status; Cardiometabolic risk; screening strategy; precision prevention; public health screening; cost-effectiveness},
	year = {2026},
	eissn = {2072-6643},
	orcid-numbers = {Szőllősi, Gergő József/0000-0002-4126-0058; Pázmándi, Eszter Melinda/0000-0002-0634-4002; Fekete, Mónika/0000-0001-8632-2120}
}

@article{MTMT:37107126,
	title = {Traditional Food Systems as Nutrient Optimization Architectures: Mechanisms of Bioavailability and Dietary Resilience},
	url = {https://m2.mtmt.hu/api/publication/37107126},
	author = {Zugravu, Corina-Aurelia and Petre, Marta and Constantin, Ciprian},
	doi = {10.3390/nu18091448},
	journal-iso = {NUTRIENTS},
	journal = {NUTRIENTS},
	volume = {18},
	unique-id = {37107126},
	abstract = {Traditional food systems have historically sustained nutrient adequacy under conditions of environmental variability and limited food diversity, yet their underlying nutritional mechanisms remain insufficiently integrated into contemporary nutrition science. This article attempts to provide a conceptual synthesis of how traditional dietary practices may function as informal nutrient optimization strategies. Drawing on evidence from nutrition science, food chemistry, and human physiology, it examines how food processing techniques (e.g., fermentation, soaking, germination, and thermal treatment), food pairing, and structural properties of foods influence nutrient bioavailability, absorption, and metabolic responses. Across diverse dietary contexts—including Mediterranean, agrarian cereal–legume, and East Asian-type patterns—recurring mechanisms emerge that can boost mineral solubility, improve protein digestibility and amino acid balance, facilitate vitamin absorption, and modulate glycemic responses. These effects are mediated not only by nutrient content but by interactions within the food structure and at the meal level. The synthesis supports a reframing of traditional diets as functional nutritional architectures in which processing and dietary configuration may enhance nutrient utilization efficiency. From this perspective, nutrient adequacy arises from coordinated structural features rather than from maximal nutrient density alone. The findings can be influential in contemporary nutrition research and policy, highlighting the need to move beyond reductionist intake-based models toward integrated approaches that account for bioavailability, metabolic handling, and dietary context. Several transferable principles of nutrient optimization are proposed, offering a framework for designing nutritionally efficient and resilient diets in modern settings.},
	year = {2026},
	eissn = {2072-6643},
	orcid-numbers = {Zugravu, Corina-Aurelia/0000-0002-3563-6987; Constantin, Ciprian/0000-0003-3355-5048}
}

@article{MTMT:37109056,
	title = {Dietary Polyphenols in Brain Aging: Molecular Mechanisms and Implications for Neurodegeneration},
	url = {https://m2.mtmt.hu/api/publication/37109056},
	author = {Mózes, Noémi and Varga, János Tamás and Szwajgier, D. and Kryczyk-Poprawa, A. and Zábó, Virág and Lehoczki, Andrea Marianna and Lipécz, Ágnes and Csípő, Tamás and Fazekas-Pongor, Vince and Major, Dávid and Varga, Péter and Matiscsák, Attila and Fekete, Mónika},
	doi = {10.3390/nu18091470},
	journal-iso = {NUTRIENTS},
	journal = {NUTRIENTS},
	volume = {18},
	unique-id = {37109056},
	year = {2026},
	eissn = {2072-6643},
	orcid-numbers = {Varga, János Tamás/0000-0002-8552-1336; Zábó, Virág/0000-0001-8948-8636; Fazekas-Pongor, Vince/0000-0002-6405-4003; Major, Dávid/0000-0002-6108-9745; Matiscsák, Attila/0000-0003-2097-602X; Fekete, Mónika/0000-0001-8632-2120}
}

@article{MTMT:37223210,
	title = {Exploratory Genome-Wide Association Study of Grapefruit Intake and Its Potential Link to Obesity Risk in US Cohorts},
	url = {https://m2.mtmt.hu/api/publication/37223210},
	author = {Bae, Ji Hyun and Kang, Hyunju},
	doi = {10.3390/nu18091319},
	journal-iso = {NUTRIENTS},
	journal = {NUTRIENTS},
	volume = {18},
	unique-id = {37223210},
	keywords = {Genome-Wide Association Study; precision nutrition; Obesity risk; grapefruit intake},
	year = {2026},
	eissn = {2072-6643}
}

@article{MTMT:37226504,
	title = {Mogrosides as Dual-Function Sweeteners: A Comprehensive Review of Extraction, Metabolism, Antidiabetic Mechanisms, and Food Applications},
	url = {https://m2.mtmt.hu/api/publication/37226504},
	author = {Feng, Qiqi and Wang, Tao and Wang, Qing and Pan, Hongyu and Zhong, Yujie and Zhuang, Yongliang},
	doi = {10.3390/nu18091342},
	journal-iso = {NUTRIENTS},
	journal = {NUTRIENTS},
	volume = {18},
	unique-id = {37226504},
	keywords = {EXTRACTION; metabolism; food industry; antidiabetic activity; mogrosides},
	year = {2026},
	eissn = {2072-6643}
}

@article{MTMT:37228046,
	title = {Vitamin D in Type 2 Diabetes Mellitus According to Diabetic Kidney Disease Stage: What Is the Target in Clinical Practice?},
	url = {https://m2.mtmt.hu/api/publication/37228046},
	author = {Felicio, Joao Soares and Ruivo, Licia Oliveira and Bezerra, Inessa Silveira and do Carmo, Maria Eduarda Nunes Avelar and Fernandes, Isabel Jacob and Lobo, Beatriz Dias and Silva, Lilian de Souza D'Albuquerque and de Melo, Franciane Trindade Cunha and de Souza, Ana Carolina Contente Braga and De Queiroz, Natercia Neves Marques and dos Santos, Marcia Costa and De Moraes, Lorena Vilhena and Barros, Mayana Batista and Fernandes, Alan Pinheiro and da Penha, Paula Gabriella Costa and Rodrigues, Ana Clara Fleury da Fonseca and Piani, Pedro Paulo Freire and Motta, Ana Regina Bastos and Leal, Valeria Suenya Galvao and dos Reis, Melissa de Sa Oliveira and Lobato, Alyne Maciel and Felicio, Karem Mileo and De Figueiredo, Priscila Boaventura Barbosa},
	doi = {10.3390/nu18091408},
	journal-iso = {NUTRIENTS},
	journal = {NUTRIENTS},
	volume = {18},
	unique-id = {37228046},
	keywords = {diabetes mellitus; type 2 diabetes mellitus; vitamin D; Diabetic kidney disease; vitamin D standards},
	year = {2026},
	eissn = {2072-6643}
}

@article{MTMT:37228218,
	title = {Identifying Patients with Colorectal Cancer Likely to Benefit from a Trimodal Prehabilitation Prior to Surgery},
	url = {https://m2.mtmt.hu/api/publication/37228218},
	author = {Suszták, Nóra and Fülöp, András and Lakatos, Lóránd and Herovi, Dominic and Cho, Junghyun and Timar, Petra and Golub, Jozsef and Mihaly, Izabella and Marton, Jozsef Tamas and Szijártó, Attila and Bánky, Balázs},
	doi = {10.3390/nu18091369},
	journal-iso = {NUTRIENTS},
	journal = {NUTRIENTS},
	volume = {18},
	unique-id = {37228218},
	keywords = {Patient Selection; colorectal cancer; colorectal surgery; Frailty; enhanced recovery after surgery; postoperative morbidity; ERAS; Myosteatosis; trimodal prehabilitation},
	year = {2026},
	eissn = {2072-6643},
	orcid-numbers = {Bánky, Balázs/0000-0002-4297-9072}
}