@article{MTMT:34716364, title = {Clinical evaluation of posterior flowable short fiber-reinforced composite restorations without proximal surface coverage}, url = {https://m2.mtmt.hu/api/publication/34716364}, author = {ElAziz, Rawda H Abd and ElAziz, Sherifa A Abd and ElAziz, Possy M Abd and Fráter, Márk Tibor and Vallittu, Pekka K and Lassila, Lippo and Garoushi, Sufyan}, doi = {10.1007/s10266-024-00905-5}, journal-iso = {ODONTOLOGY}, journal = {ODONTOLOGY}, unique-id = {34716364}, issn = {1618-1247}, abstract = {The purpose of this clinical trail was to assess the clinical behavior of posterior composite restorations supported by a substantial foundation of flowable short fiber-reinforced composite SFRC (everX Flow, GC, Japan) used without proximal surface coverage with particulate filler resin composite (PFC). Seventy patients (20 males, 50 females; mean age: 30±10years) were randomly enrolled in this trial. Patients received direct restorations of either SFRC covered only on the occlusal surface (1-2mm) by conventional PFC composite (G-anial Posterior, GC), or plain conventional PFC composite without fiber-reinforcement, in Class II cavities in premolar and molar vital teeth. One operator made all restorations using one-step, self-etch bonding agent (G-anial Bond, GC) according to manufacturers' recommendations. Two blinded trained operators evaluated the restorations at baseline, at 6, 12 and 18months using modified USPHS criteria. Results indicated that, in both groups and at different follow-up intervals, according to evaluated criteria, restorations were rated mostly with best score (Alpha) (p>0.05). For the marginal integrity after 6months, a single case in the intervention [increased to 3 (8.8%) after 18months] and 3 (9.7%) cases of the control group [increased to 4 (12.9%) after 18months] had Bravo score but with no significant difference (p>0.05). For color match measured after 6 and 18months, three (8.8%) cases had Bravo score in the intervention group. The use of flowable SFRC composite without any PFC surface coverage proximally in Class II restorations demonstrated satisfactory clinical outcome throughout the 18-month follow-up.}, year = {2024}, eissn = {1618-1255}, orcid-numbers = {Fráter, Márk Tibor/0000-0002-0365-1613} } @article{MTMT:34635056, title = {Relationship between soft tissue dimensions and tomographic radial root position classification system for immediate implant installation}, url = {https://m2.mtmt.hu/api/publication/34635056}, author = {Rodrigues, Diogo Moreira and Gluckman, Howard and Pontes, Carla Cruvinel and Januario, Alessandro Lourenco and Petersen, Rodrigo Lima and de Moraes, Jose Rodrigo and Barboza, Eliane Porto}, doi = {10.1007/s10266-023-00897-8}, journal-iso = {ODONTOLOGY}, journal = {ODONTOLOGY}, unique-id = {34635056}, issn = {1618-1247}, keywords = {PHENOTYPE; cone beam computed tomography; gingiva; Dental Implants; Immediate implants; 3-D imaging}, year = {2024}, eissn = {1618-1255} } @article{MTMT:34606800, title = {Long-lasting adverse effects of short-term stress during the suckling-mastication transition period on masticatory function and intraoral sensation in rats}, url = {https://m2.mtmt.hu/api/publication/34606800}, author = {Katagiri, Ayano and Yamada, Masaharu and Sato, Hajime and Toyoda, Hiroki and Niwa, Hitoshi and Kato, Takafumi}, doi = {10.1007/s10266-023-00887-w}, journal-iso = {ODONTOLOGY}, journal = {ODONTOLOGY}, unique-id = {34606800}, issn = {1618-1247}, abstract = {Early-life stress affects brain development, eventually resulting in adverse behavioral and physical health consequences in adulthood. The present study assessed the hypothesis that short-term early-life stress during infancy before weaning, a period for the maturation of mastication and sleep, poses long-lasting adverse effects on masticatory function and intraoral sensations later in life.Rat pups were exposed to either maternal separation (MS) or intermittent hypoxia (IH-Infancy) for 6 h/day in the light/sleep phase from postnatal day (P)17 to P20 to generate "neglect" and "pediatric obstructive sleep apnea" models, respectively. The remaining rats were exposed to IH during P45-P48 (IH-Adult). Masticatory ability was evaluated based on the rats' ability to chew pellets and bite pasta throughout the growth period (P21-P70). Intraoral chemical and mechanical sensitivities were assessed using two-bottle preference drinking tests, and hind paw pain thresholds were measured in adulthood (after P60).No differences were found in body weight, grip force, and hind paw sensitivity in MS, IH-Infancy, and IH-Adult rats compared with naive rats. Masticatory ability was lower in MS and IH-Infancy rats from P28 to P70 than in naive rats. MS and IH-Infancy rats exhibited intraoral hypersensitivity to capsaicin and mechanical stimulations in adulthood. The IH-Adult rats did not display inferior masticatory ability or intraoral hypersensitivity.In conclusion, short-term early-life stress during the suckling-mastication transition period potentially causes a persistent decrease in masticatory ability and intraoral hypersensitivity in adulthood. The period is a "critical window" for the maturation of oral motor and sensory functions.}, keywords = {HYPOXIC STRESS; maternal separation; Masticatory function; Intraoral hypersensitivity; Suckling-mastication transition period}, year = {2024}, eissn = {1618-1255} } @article{MTMT:34596743, title = {Evaluation of the antimicrobial efficacy of different nonsteroidal anti-inflammatory drugs alone or in combination with calcium hydroxide intracanal medicament: an in vitro study}, url = {https://m2.mtmt.hu/api/publication/34596743}, author = {Al-Sadah, Attika Y. and Aleraky, Doaa M. and Abuohashish, Hatem M. and Atmeh, Amre R.}, doi = {10.1007/s10266-023-00892-z}, journal-iso = {ODONTOLOGY}, journal = {ODONTOLOGY}, unique-id = {34596743}, issn = {1618-1247}, abstract = {This study explored the antimicrobial effects of ketoprofen, piroxicam, and celecoxib alone or combined with calcium hydroxide (CH) against two strains of Enterococcus faecalis (E. faecalis) and assessed the influence of such combinations on the pH of CH. Minimum inhibitory concentrations (MICs) of the three tested NSAIDs were determined. Tested pastes were placed into wells punched in seeded agar plates and the bacterial inhibition zones were measured. Antibiofilm activity was assessed against 3 weeks of biofilm induced in bovine dentine blocks. The pH of the pastes was measured at four-time intervals. MIC values were 3.12, 25, and 25 mg/ml for ketoprofen, piroxicam, and celecoxib, respectively, and were similar for both bacterial strains except for celecoxib, which showed 8% growth at the highest tested concentration against vancomycin-resistant E. faecalis. Ketoprofen had the largest mean inhibition zone that was comparable to CH. None of the six tested pastes exhibited antibiofilm activity of a significant level in comparison to CH. A noticeable increase in the antibiofilm activity was found when 20% NSAIDs were added to CH while maintaining an alkaline pH. Ketoprofen was found to be the most effective among the tested NSAIDs. Although its effect was comparable to CH, adding ketoprofen at a ratio of 20% resulted in 50% higher antimicrobial action than CH alone. Accordingly, incorporating NSAIDs in inter-appointment dressing has the potential to utilize their anti-inflammatory, local analgesic, and antibacterial actions, which overcome the limitations of CH and improve the outcome of root canal treatment.}, keywords = {piroxicam; Enterococcus faecalis; calcium hydroxide; ketoprofen; celecoxib}, year = {2024}, eissn = {1618-1255} } @article{MTMT:34563649, title = {Aberrated PSMA1 expression associated with clinicopathological features and prognosis in oral squamous cell carcinoma}, url = {https://m2.mtmt.hu/api/publication/34563649}, author = {Rukmini, D. and Kannan, B. and Pandi, C. and Pandi, A. and Prasad, P. and Jayaseelan, V.P. and Arumugam, P.}, doi = {10.1007/s10266-023-00883-0}, journal-iso = {ODONTOLOGY}, journal = {ODONTOLOGY}, unique-id = {34563649}, issn = {1618-1247}, abstract = {Oral squamous cell carcinoma (OSCC) is a globally prevalent cancer with significant mortality rates. OSCC a predominant subtype of head and neck squamous cell carcinoma (HNSCC), poses a substantial health burden. Despite advancements in diagnosis and therapy, OSCC prognosis remains poor. The 26S proteasome, a cellular protein degradation complex, is associated with cancer, including PSMA1, a proteasomal subunit, which is upregulated in various cancers. We analyzed PSMA1 expression using TCGA data, validated it in OSCC samples using real-time PCR, and explored its role through various databases. Tumor and adjacent normal tissues from OSCC patients were examined, and PSMA1 expression was analyzed. Survival analysis assessed the impact of PSMA1 on patient outcomes, while immune infiltration was examined using the TIMER database. GeneMANIA, STRING, and Metascape were utilized for gene interaction and pathway analysis. PSMA1 was significantly upregulated in OSCC and HNSCC. Its overexpression correlated with advanced clinicopathological features and poorer prognosis in HNSCC patients. PSMA1 expression is also related to immune cell infiltration. Gene interaction analysis revealed PSMA1 involvement in proteolysis regulation, suggesting its potential as a therapeutic target. PSMA1 upregulation in HNSCC association with adverse clinicopathological features and prognosis underscores its potential significance. Further research is warranted to elucidate its molecular mechanisms and therapeutic potential in OSCC management. © 2024, The Author(s), under exclusive licence to The Society of The Nippon Dental University.}, keywords = {CANCER; GENETICS; MORTALITY; Health; novel biomarker}, year = {2024}, eissn = {1618-1255} } @article{MTMT:34556813, title = {Physicochemical and mechanical properties of preheated composite resins for luting ceramic laminates}, url = {https://m2.mtmt.hu/api/publication/34556813}, author = {da Silva, Fabio Augusto Soares and Paschoini, Vitoria Leite and Cortez, Thiago Vinicius and Corona, Silmara Aparecida Milori and Souza-Gabriel, Aline Evangelista}, doi = {10.1007/s10266-023-00880-3}, journal-iso = {ODONTOLOGY}, journal = {ODONTOLOGY}, unique-id = {34556813}, issn = {1618-1247}, year = {2024}, eissn = {1618-1255}, orcid-numbers = {Paschoini, Vitoria Leite/0000-0001-9233-1381} } @article{MTMT:34364693, title = {Xenogeneic collagen matrix vs. connective tissue graft for the treatment of multiple gingival recession: a systematic review and meta-analysis}, url = {https://m2.mtmt.hu/api/publication/34364693}, author = {Zegarra-Caceres, Lorena and Orellano-Merluzzi, Ariana and Muniz, Francisco Wilker Mustafa Gomes and de Souza, Sergio Luis Scombatti and Faveri, Marcelo and Meza-Mauricio, Jonathan}, doi = {10.1007/s10266-023-00863-4}, journal-iso = {ODONTOLOGY}, journal = {ODONTOLOGY}, volume = {112}, unique-id = {34364693}, issn = {1618-1247}, abstract = {The aim of this systematic review (SR) compared the effect of xenogeneic collagen matrix (XCM) vs. connective tissue graft (CTG) for the treatment of multiple gingival recession (MGR) Miller Class I and II or Cairo type I. Five databases were searched up to August 2022 for randomized clinical trials (RCTs) comparing the clinical effects of XCM vs. CTG in the treatment of MGR. The random effects model of mean differences was used to determine reduction of gingival recession (GR), gain in keratinized tissue width (KTW), gain in gingival thickness (GT) and gain in clinical attachment level (CAL). The risk ratio was used to complete root coverage (CRC) at 6 and 12 months. 10 RCTs, representing 1095 and 649 GR at 6 and 12 months, respectively, were included in this SR. The meta-analysis showed no statistically significant difference in GR reduction, KTW gain GT gain or CAL gain between groups at 6 months. However, at 12 months of follow-up, differences favoring the control group were observed (p < 0.05). CRC was significantly higher in the CTG group at 6 and 12 months. Regarding dentine hypersensitivity (DH), no statistically significant differences were found between groups at 6 and 12 months of follow-up (p < 0.05). At 12 months, CTG showed significantly superior clinical results in the treatment of MGR: however, this difference was not observed in the decrease of DH.}, keywords = {connective tissue graft; coronally advanced flap; acellular dermis; gingival recessions}, year = {2024}, eissn = {1618-1255}, pages = {317-340} } @article{MTMT:33885216, title = {Push-out bond strength and SEM fractographical analysis of hollow fibre posts used with self-adhesive resin cement: a pilot study}, url = {https://m2.mtmt.hu/api/publication/33885216}, author = {Generali, Luigi and Veneri, Federica and Forabosco, Eleonora and Cavani, Francesco and Piergianni, Veronica and Sassatelli, Paolo and Checchi, Vittorio and Pedulla, Eugenio}, doi = {10.1007/s10266-023-00820-1}, journal-iso = {ODONTOLOGY}, journal = {ODONTOLOGY}, volume = {112}, unique-id = {33885216}, issn = {1618-1247}, abstract = {Detachment is the major cause of failure of endodontic fibre posts. Hollow posts have been recently introduced to overcome such issue. The primary aim of this pilot study was to compare the push-out bond strength of hollow posts and traditional solid posts. Eight round-shaped single-canal premolars extracted for periodontal reason were selected as sample and equally randomized into two groups: (i) traditional solid fibre posts-TECH21xop and ii) hollow fibre posts-TECHOLE. A dual-curing self-adhesive cement (new TECHCEM) was used for posts placement. Six horizontal sections-two from each portion of the root (coronal, middle and apical)-were obtained from each sample root, yielding a total of 24 sections for each group. Push-out test was performed on the sections and bond strength values were compared between groups and within each group. Scanning electron microscope (SEM) fractographical analysis was conducted on each section. Additional SEM and EDX analyses were performed on new samples of both posts, to assess fibres density and distribution, and the chemical composition of the fibres and the matrix. Hollow posts showed a significantly higher push-out bond strength (6.36 +/- 1.22 MPa) than solid posts (3.64 +/- 1.62 MPa). Among the three root portions of the same group, there was no significant difference in bond strength. In both groups, the most frequent type of fracture was a mixed adhesive failure with the cement covering 0 to 50% of the post perimeter. Hollow post fibres appear more similar in size and have a more homogeneous distribution, compared to solid posts. The two post types also have different chemical compositions.}, keywords = {push-out bond strength; Fibre hollow posts; Fibre posts; Fractographical analysis; Self-adhesive cement}, year = {2024}, eissn = {1618-1255}, pages = {158-168}, orcid-numbers = {Generali, Luigi/0000-0003-3764-7046} } @article{MTMT:33831134, title = {Fracture behavior of short fiber-reinforced CAD/CAM inlay restorations after cyclic fatigue aging}, url = {https://m2.mtmt.hu/api/publication/33831134}, author = {Garoushi, S. and Barlas, D. and Vallittu, P. K. and Uctasli, M. B. and Lassila, L.}, doi = {10.1007/s10266-023-00815-y}, journal-iso = {ODONTOLOGY}, journal = {ODONTOLOGY}, volume = {112}, unique-id = {33831134}, issn = {1618-1247}, abstract = {The aim of this study was to assess the fracture behavior of molar teeth restored with MOD inlays made of experimental short fiber-reinforced CAD/CAM composite block (SFRC CAD) before and after cyclic fatigue aging. Standardized MOD cavities were prepared on 60 intact mandibular molars. Three groups of CAD/CAM made inlay restorations (Cerasmart 270, Enamic, and SFRC CAD) were fabricated (n = 20/group). All restorations were luted with self-adhesive dual-cure resin cement (G-Cem One). Half of restored teeth per each group (n = 10) were quasi-statically loaded until fracture without aging. The other half underwent cyclic fatigue aging for 500,000 cycles (F-max = 150 N) before being loaded quasi-statically until fracture. Then, the fracture type was visually inspected. The microstructure and elemental content of CAD/CAM materials were assessed using SEM and EDS. Two-way analysis of variance (ANOVA) was used to statistically examine the data, and it was followed by the Tukey HSD test (alpha = 0.05). ANOVA demonstrated that both material type and aging had a significant effect (p < 0.05) on the load-bearing capacity values of the restorations. Teeth restored with SFRC CAD showed significantly the highest (p < 0.05) load-bearing capacity (2535 +/- 830 N) after fatigue aging among all groups. SEM images showed the ability of short fibers in SFRC CAD composite to redirect and hinder crack propagation. With regard to fracture mode, Enamic group revealed 85% of catastrophic failure (vs. 45% and 10% for Cerasmart 270 and SFRC CAD, respectively). Large MOD cavities on molar teeth were most favorably restored with SFRC CAD inlays, yielding the highest load-bearing capacity and more restorable failures.}, keywords = {RESISTANCE; composite; MECHANICAL-PROPERTIES; Inlays; CAD; CAM; Short fiber composite; Fatigue aging}, year = {2024}, eissn = {1618-1255}, pages = {138-147} } @article{MTMT:34617659, title = {Effect of incorporation of calcium polyphosphate sub-microparticles in low-concentration bleaching gels on physical properties of dental enamel}, url = {https://m2.mtmt.hu/api/publication/34617659}, author = {dos Anjos, Hemanuelly Albuquerque and Ortiz, Mariangela Ivette Guanipa and Aguiar, Flavio Henrique Baggio and dos Santos, Juliana Jarussi and Rodrigues, Ubirajara Pereira and Rischka, Klaus and Lima, Debora Alves Nunes Leite}, doi = {10.1007/s10266-023-00875-0}, journal-iso = {ODONTOLOGY}, journal = {ODONTOLOGY}, unique-id = {34617659}, issn = {1618-1247}, abstract = {Aim To evaluate the bleaching efficacy and effects on enamel properties of experimental gels with carbamide peroxide (CP; 10%) or hydrogen peroxide (HP; 6%) containing calcium polyphosphate sub-microparticles (CaPPs).Methods A total of 216 bovine tooth specimens were divided for microhardness and color analyses (n = 108) and block randomized into nine groups (n = 12): (G1) commercial CP (Whiteness Perfect, FGM; Brazil); (G2) experimental CP; (G3) CP-0.5%CaPPs; (G4) CP-1.5%CaPPs; (G5) commercial HP (Potenza Bianco, PHS; Brazil); (G6) experimental HP; (G7) HP-0.5%CaPPs; (G8) HP-1.5%CaPPs; (G9) artificial saliva. The gels' pH values were determined with a bench pH meter. Color (Delta E, Delta E-00, Delta WID) and microhardness variation were evaluated before and after the therapy. Part of the specimens used for microhardness was submitted to the scanning electron microscopy (SEM) (n = 3) and energy-dispersive X-ray spectroscopy EDX (n = 3) analyses. Statistical analyses were performed in the R statistical software (alpha = 0.05). Linear mixed models for repeated measures in time were used to analyze microhardness and L* values. Generalized linear models were used to analyze the a*, b*, Delta E, Delta E-00, and Delta WID, considering a group effect. The EDX data were analyzed using a one-way ANOVA with Tukey's test.Results The gels' pH remained over 6,0. All gels effectively bleached the specimens and did not differ significantly. When compared to the control group, the hardness was significantly lower in the G1, G2, G6, and G7 groups. The G3, G4, G5, and G8 groups did not differ significantly (p > 0.05).Conclusion The incorporation of CaPPs in low-concentration whitening gels reduces its negative effects on microhardness without interfering with their bleaching efficacy.}, keywords = {calcium; Peroxides; Dental Enamel; polyphosphates; Dental bleaching}, year = {2023}, eissn = {1618-1255} }