@article{MTMT:35659221, title = {Calcific versus non-calcific plaque: a CAD-RADS and FFRCT study}, url = {https://m2.mtmt.hu/api/publication/35659221}, author = {Murphy, D. and Graby, J. and Hudson, B. and Lowe, R. and Carson, K. and Kandan, S.R. and McKenzie, D. and Khavandi, A. and Rodrigues, J.C.L.}, doi = {10.1007/s10554-024-03281-x}, journal-iso = {INT J CARDIOVAS IMAG}, journal = {INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING}, unique-id = {35659221}, issn = {1569-5794}, year = {2024}, eissn = {1875-8312} } @article{MTMT:35641591, title = {Lipid-related radiomics of low-echo carotid plaques is associated with diabetic stroke and non-diabetic coronary heart disease}, url = {https://m2.mtmt.hu/api/publication/35641591}, author = {Chen, Qiaofei and Li, Hongwei and Xie, Wei and Abudukeremu, Ayiguli and Wen, Kexin and Liu, Wenhao and Mai, Jingting and Xu, Xiaolin and Zhang, Yuling}, doi = {10.1007/s10554-024-03296-4}, journal-iso = {INT J CARDIOVAS IMAG}, journal = {INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING}, unique-id = {35641591}, issn = {1569-5794}, abstract = {Carotid plaque radiomics-included models have increased the predictive capacity of cardiovascular risk, but the radiomic features of these models were inconsistent in previous studies. Lipids could be used to select the most important radiomic feature. A retrospective case-control study was performed in 153 diabetic and 76 non-diabetic patients with carotid plaque detected by ultrasound. Cerebro-cardiovascular disease (CCD), comprising coronary heart disease (CHD) and stroke, was the primary outcome. Clinical variables and radiomic features of longitudinal carotid plaque images were collected. Principal component analyses were used to compare the power of radiomic and lipid features in discrimination between diabetes, CCD patients, and their opposites. Partial least square regression, logistic regression analyses, and least absolute shrinkage and selection operator (LASSO) regression were performed for high-risk radiomic features. The diagnostic capacity of the models was evaluated. PCA based on radiomics or lipids did not show good discrimination of diabetes, CCD, and their opposites. There were 6 overlapping radiomic features associated with lipid profiles, but only original_firstorder_Mean was negatively associated with diabetic stroke [adjusted OR = 0.468 (0.243-0.902), P = 0.023] and nondiabetic CHD [adjusted OR = 0.311 (0.123-0.783), P = 0.013]. The associations remained independent in the LASSO regression models (beta=-0.032 for diabetic stroke, and - 0.026 for non-diabetic CHD). The diagnostic capacity of lipid-related radiomics for diabetic stroke (0.556 to 0.688) and non-diabetic CHD (0.690 to 0.783) was increased by the combination of these clinical variables. Carotid plaque radiomics is associated with lipids and stroke in diabetes, and quantitative features are useful for therapeutic guidance and cardiovascular risk evaluation in clinical use.}, keywords = {ATHEROSCLEROSIS; LIPIDS; MORTALITY; CARDIOVASCULAR RISK-FACTORS; Cardiac & Cardiovascular Systems; Carotid plaque; ultrasound radiomics; Cerebro-cardiovascular disease}, year = {2024}, eissn = {1875-8312} } @article{MTMT:35641590, title = {Pre-interventional renal artery calcification and survival after transcatheter aortic valve implantation}, url = {https://m2.mtmt.hu/api/publication/35641590}, author = {Winkler, N. E. and Galantay, J. and Hebeisen, M. and Donati, T. G. and Stehli, J. and Kasel, A. M. and Alkadhi, H. and Nguyen-Kim, T. D. L. and Tanner, F. C.}, doi = {10.1007/s10554-024-03295-5}, journal-iso = {INT J CARDIOVAS IMAG}, journal = {INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING}, unique-id = {35641590}, issn = {1569-5794}, abstract = {The prognostic significance of renal artery calcification (RAC) is unknown in patients with severe aortic stenosis (AS) eligible for transcatheter aortic valve implantation (TAVI). RAC can be assessed by computed tomography (CT) performed during pre-interventional planning for TAVI. This study aimed at investigating the utility of RAC for predicting survival after TAVI. In this longitudinal cohort study, RAC volume was measured by CT in 268 consecutive patients with severe AS undergoing TAVI. Association of RAC with mortality was assessed using Cox regression analysis. RAC was evaluated as a binary parameter and in a supplementary analysis as a logarithmically transformed continuous variable. Over a median follow-up time of 9.6 years, 237 (88.4%) patients died, with 174 (73.4%) deaths attributable to a cardiovascular cause. RAC was highly prevalent (N = 150 (86.2%)) among patients suffering cardiovascular death. Competing risk cumulative incidence curves revealed a higher occurrence of cardiovascular death in patients with RAC (P-value = 0.008), while this was not the case for non-cardiovascular death (P-value = 0.71). RAC was independently associated with cardiovascular death (HR 1.61 [95% CI: 1.01-2.57]; P = 0.047) after adjustment for age, sex, cardiovascular risk factors, impaired renal function, and aortic valve calcification. The presence or absence of RAC rather than its volume was important in all the analyses. RAC is a strong and independent predictor of cardiovascular death in patients with severe AS undergoing TAVI. Given its favourable properties for event prediction, RAC may be considered valuable for prognostic assessment of TAVI patients.Graphical AbstractOccurence and prognostic implications of pre-interventional renal artery calcification after transcatheter aortic valve implantation. CV, cardiovascular; CVD, cardiovascular disease; LVOT, left ventricular outflow tract; CT, computed tomography; RAC, renal artery calcification; ST, sinotubular; AA, ascending aorta; TAVI, transcatheter aortic valve implantation This pioneering study investigated the association between renal artery calcification (RAC) and cardiovascular mortality in 268 consecutive patients with severe aortic stenosis (AS) eligible for transcatheter aortic valve implantation (TAVI). The findings indicated a robust association between RAC and cardiovascular death, independent of traditional risk factors such as age, sex, cardiovascular risk factors, renal function, and aortic valve calcification. Notably, the presence of RAC, rather than its volume, was significant. The readily available imaging marker RAC was investigated for the first time in this context and emerged as a strong and independent predictor of cardiovascular death in severe AS patients undergoing TAVI. Conversely, the absence of RAC reduced the risk of cardiovascular death by approximately 40%. In conclusion, this study suggests that RAC has significant prognostic value in assessing TAVI patients, underscoring its importance in predicting cardiovascular outcomes in these patients.}, keywords = {MECHANISMS; MORTALITY; QUANTIFICATION; Prognosis; computed tomography; GUIDELINES; STENOSIS; Renal; transthoracic echocardiography; PROGNOSTIC VALUE; RECOMMENDATIONS; Cardiac & Cardiovascular Systems; aortic stenosis; AMERICAN-SOCIETY; EUROPEAN-ASSOCIATION}, year = {2024}, eissn = {1875-8312} } @article{MTMT:35561403, title = {Tissue characterisation with cardiac computed tomography: an intriguing possibility becoming reality}, url = {https://m2.mtmt.hu/api/publication/35561403}, author = {Guglielmo, M. and Fedele, D.}, doi = {10.1007/s10554-024-03285-7}, journal-iso = {INT J CARDIOVAS IMAG}, journal = {INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING}, unique-id = {35561403}, issn = {1569-5794}, year = {2024}, eissn = {1875-8312} } @article{MTMT:35486798, title = {ECHO-MPS, a dual modality strategy of cardiac imaging to identify myocardial ischemia}, url = {https://m2.mtmt.hu/api/publication/35486798}, author = {Szmigielski, C.A. and Sabharwal, N. and Newton, J.D. and Becher, H.}, doi = {10.1007/s10554-024-03257-x}, journal-iso = {INT J CARDIOVAS IMAG}, journal = {INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING}, volume = {40}, unique-id = {35486798}, issn = {1569-5794}, year = {2024}, eissn = {1875-8312}, pages = {2513-2521} } @article{MTMT:35458538, title = {Evolving capabilities of computed tomography imaging for transcatheter valvular heart interventions – new opportunities for precision medicine}, url = {https://m2.mtmt.hu/api/publication/35458538}, author = {Androshchuk, V. and Montarello, N. and Lahoti, N. and Hill, S.J. and Zhou, C. and Patterson, T. and Redwood, S. and Niederer, S. and Lamata, P. and De, Vecchi A. and Rajani, R.}, doi = {10.1007/s10554-024-03247-z}, journal-iso = {INT J CARDIOVAS IMAG}, journal = {INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING}, unique-id = {35458538}, issn = {1569-5794}, year = {2024}, eissn = {1875-8312} } @article{MTMT:35436655, title = {Selective FFRCT testing in suspected stable angina in clinical practice - initial experiences}, url = {https://m2.mtmt.hu/api/publication/35436655}, author = {Thangavel, S. and Madsen, K.T. and Rønnow, Sand N.P. and Veien, K.T. and Deibjerg, L. and Husain, M. and Hosbond, S. and Alan, D.H. and Øvrehus, K.A. and Junker, A. and Mortensen, J. and Thomsen, K.K. and Jensen, L.O. and Poulsen, T.S. and Steffensen, F.H. and Rohold, A. and Busk, M.}, doi = {10.1007/s10554-024-03214-8}, journal-iso = {INT J CARDIOVAS IMAG}, journal = {INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING}, unique-id = {35436655}, issn = {1569-5794}, abstract = {Coronary CT angiography (CTA) derived fractional flow reserve (FFRCT) is recommended for physiological assessment in intermediate coronary stenosis for guiding referral to invasive coronary angiography (ICA). In this study, we report real-world data on the feasibility of implementing a CTA/FFRCT test algorithm as a gatekeeper to ICA at referral hospitals. Retrospective all-comer study of patients with new onset stable symptoms and suspected coronary stenosis (30–89%) by CTA. Evaluation of CTA datasets, interpretation of FFRCT analysis, and decisions on downstream testing were performed by skilled CT-cardiologists. CTA was performed in 3974 patients, of whom 381 (10%) were referred directly to ICA, whereas 463 (12%) to non-invasive functional testing: FFRCT 375 (81%) and perfusion imaging 88 (19%). FFRCT analysis was rejected in 8 (2%) due to inadequate CTA image quality. Number of patients deferred from ICA after FFRCT was 267 (71%), while 100 (27%) were referred to ICA. Obstructive coronary artery disease (CAD) was confirmed in 62 (62%) patients and revascularization performed in 53 (53%). Revascularization rates, n (%), were higher in patients undergoing FFRCT-guided versus CTA-guided referral to ICA: 30–69% stenosis, 28 (44%) versus 8 (21%); 70–89% stenosis, 39 (69%) versus 25 (46%), respectively, both p < 0.05. Implementation of FFRCT at referral hospitals was feasible, reduced the number of invasive procedures, and increased the revascularization rate. © The Author(s) 2024.}, keywords = {Coronary Angiography; computed tomography; Myocardial Revascularization; angina pectoris; Myocardial fractional flow reserve; Xray}, year = {2024}, eissn = {1875-8312} } @article{MTMT:35386898, title = {Potential prognostic impact of left-ventricular global longitudinal strain in analysis of whole-heart myocardial mechanics in nonischemic dilated cardiomyopathy}, url = {https://m2.mtmt.hu/api/publication/35386898}, author = {Melinyte-Ankudavice, Karolina and Marcinkeviciene, Karolina and Galnaitiene, Gryte and Bucius, Paulius and Lapinskas, Tomas and Ereminiene, Egle and Sakalyte, Gintare and Jurkevicius, Renaldas}, doi = {10.1007/s10554-024-03184-x}, journal-iso = {INT J CARDIOVAS IMAG}, journal = {INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING}, unique-id = {35386898}, issn = {1569-5794}, keywords = {heart failure; cardiac magnetic resonance; global longitudinal strain; non-ischemic dilated cardiomyopathy; Early primary outcomes; whole-heart mechanics}, year = {2024}, eissn = {1875-8312} } @article{MTMT:35386846, title = {Association between cardiac time intervals and incident heart failure after acute coronary syndrome}, url = {https://m2.mtmt.hu/api/publication/35386846}, author = {Bjerregaard, Caroline Lokke and Olsen, Flemming Javier and Skaarup, Kristoffer Grundtvig and Jorgensen, Peter Godsk and Galatius, Soren and Pedersen, Sune and Iversen, Allan and Biering-Sorensen, Tor}, doi = {10.1007/s10554-024-03206-8}, journal-iso = {INT J CARDIOVAS IMAG}, journal = {INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING}, unique-id = {35386846}, issn = {1569-5794}, keywords = {heart failure; acute coronary syndrome; cardiac time intervals; Event timing}, year = {2024}, eissn = {1875-8312} } @article{MTMT:35382064, title = {Advanced myocardial characterization and function with cardiac CT}, url = {https://m2.mtmt.hu/api/publication/35382064}, author = {Lisi, Costanza and Moser, Lukas J. and Mergen, Victor and Klambauer, Konstantin and Ucar, Eda and Eberhard, Matthias and Alkadhi, Hatem}, doi = {10.1007/s10554-024-03229-1}, journal-iso = {INT J CARDIOVAS IMAG}, journal = {INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING}, unique-id = {35382064}, issn = {1569-5794}, keywords = {MYOCARDIUM; computed tomography; Extracellular volume; strain analysis; late enhancement; Photon-counting detector}, year = {2024}, eissn = {1875-8312} }