@article{MTMT:34840271,
	title = {Peripheral immunophenotyping reveals lymphocyte stimulation in healthy women living with hereditary breast and ovarian cancer syndrome},
	url = {https://m2.mtmt.hu/api/publication/34840271},
	author = {Balog, József Ágoston and Horti-Oravecz, Klaudia and Kövesdi, Dorottya and Bozsik, Anikó and Papp, Janos and Butz, Henriett and Patócs, Attila and Szebeni, Gábor and Grolmusz, Vince Kornél},
	doi = {10.1016/j.isci.2024.109882},
	journal-iso = {ISCIENCE},
	journal = {ISCIENCE},
	volume = {AiP},
	unique-id = {34840271},
	year = {2024},
	eissn = {2589-0042},
	pages = {109882},
	orcid-numbers = {Szebeni, Gábor/0000-0002-6998-5632}
}

@article{MTMT:34840255,
	title = {Identification of immune subsets with distinct lectin binding signatures using multi-parameter flow cytometry: correlations with disease activity in systemic lupus erythematosus},
	url = {https://m2.mtmt.hu/api/publication/34840255},
	author = {Szabó, Enikő and Faragó, Anna and Bodor, Gergely and Gémes, Nikolett and Puskás, László and Kovács, László and Szebeni, Gábor},
	doi = {10.3389/fimmu.2024.1380481},
	journal-iso = {FRONT IMMUNOL},
	journal = {FRONTIERS IN IMMUNOLOGY},
	volume = {15},
	unique-id = {34840255},
	issn = {1664-3224},
	year = {2024},
	eissn = {1664-3224},
	orcid-numbers = {Szebeni, Gábor/0000-0002-6998-5632}
}

@article{MTMT:34829278,
	title = {Comparative single-cell multiplex immunophenotyping of therapy-naive patients with rheumatoid arthritis, systemic sclerosis, and systemic lupus erythematosus shed light on disease-specific composition of the peripheral immune system},
	url = {https://m2.mtmt.hu/api/publication/34829278},
	author = {Balog, József Ágoston and Zvara, Ágnes and Bukovinszki, Vivien and Puskás, László and Balog, Attila and Szebeni, Gábor},
	doi = {10.3389/fimmu.2024.1376933},
	journal-iso = {FRONT IMMUNOL},
	journal = {FRONTIERS IN IMMUNOLOGY},
	volume = {15},
	unique-id = {34829278},
	issn = {1664-3224},
	year = {2024},
	eissn = {1664-3224},
	orcid-numbers = {Szebeni, Gábor/0000-0002-6998-5632}
}

@article{MTMT:34804520,
	title = {Cellular Immunity of Drosophila willistoni Reveals Novel Complexity in Insect Anti-Parasitoid Defense},
	url = {https://m2.mtmt.hu/api/publication/34804520},
	author = {Cinege, Gyöngyi Ilona and Fodor, K. and Magyar, Lilla Brigitta and Lipinszki, Zoltán and Hultmark, D. and Andó, István},
	doi = {10.3390/cells13070593},
	journal-iso = {CELLS-BASEL},
	journal = {CELLS},
	volume = {13},
	unique-id = {34804520},
	year = {2024},
	eissn = {2073-4409},
	orcid-numbers = {Lipinszki, Zoltán/0000-0002-2067-0832; Andó, István/0000-0002-4648-9396}
}

@article{MTMT:34790193,
	title = {Lectin-Based Immunophenotyping and Whole Proteomic Profiling of CT-26 Colon Carcinoma Murine Model.},
	url = {https://m2.mtmt.hu/api/publication/34790193},
	author = {Faragó, Anna and Zvara, Ágnes and Tiszlavicz, László and Hunyadi-Gulyás Éva, Csilla and Darula, Zsuzsanna and Hegedűs, Zoltán and Szabó, Enikő and Surguta, Sára Eszter and Tóvári, József and Puskás, László and Szebeni, Gábor},
	doi = {10.3390/ijms25074022},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {25},
	unique-id = {34790193},
	issn = {1661-6596},
	abstract = {A murine colorectal carcinoma (CRC) model was established. CT26 colon carcinoma cells were injected into BALB/c mice's spleen to study the primary tumor and the mechanisms of cell spread of colon cancer to the liver. The CRC was verified by the immunohistochemistry of Pan Cytokeratin and Vimentin expression. Immunophenotyping of leukocytes isolated from CRC-bearing BALB/c mice or healthy controls, such as CD19+ B cells, CD11+ myeloid cells, and CD3+ T cells, was carried out using fluorochrome-labeled lectins. The binding of six lectins to white blood cells, such as galectin-1 (Gal1), siglec-1 (Sig1), Sambucus nigra lectin (SNA), Aleuria aurantia lectin (AAL), Phytolacca americana lectin (PWM), and galectin-3 (Gal3), was assayed. Flow cytometric analysis of the splenocytes revealed the increased binding of SNA, and AAL to CD3 + T cells and CD11b myeloid cells; and increased siglec-1 and AAL binding to CD19 B cells of the tumor-bearing mice. The whole proteomic analysis of the established CRC-bearing liver and spleen versus healthy tissues identified differentially expressed proteins, characteristic of the primary or secondary CRC tissues. KEGG Gene Ontology bioinformatic analysis delineated the established murine CRC characteristic protein interaction networks, biological pathways, and cellular processes involved in CRC. Galectin-1 and S100A4 were identified as upregulated proteins in the primary and secondary CT26 tumor tissues, and these were previously reported to contribute to the poor prognosis of CRC patients. Modelling the development of liver colonization of CRC by the injection of CT26 cells into the spleen may facilitate the understanding of carcinogenesis in human CRC and contribute to the development of novel therapeutic strategies.},
	keywords = {colorectal carcinoma; lectin binding sugar code; proteomic analysis of murine CRC},
	year = {2024},
	eissn = {1422-0067},
	orcid-numbers = {Tóvári, József/0000-0002-5543-3204; Szebeni, Gábor/0000-0002-6998-5632}
}

@article{MTMT:34772438,
	title = {Mitochondrial Differentiation during Spermatogenesis: Lessons from Drosophila melanogaster},
	url = {https://m2.mtmt.hu/api/publication/34772438},
	author = {Vedelek, Viktor and Jankovics, Ferenc and Zádori, János and Sinka, Rita},
	doi = {10.3390/ijms25073980},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {25},
	unique-id = {34772438},
	issn = {1661-6596},
	abstract = {Numerous diseases can arise as a consequence of mitochondrial malfunction. Hence, there is a significant focus on studying the role of mitochondria in cancer, ageing, neurodegenerative diseases, and the field of developmental biology. Mitochondria could exist as discrete organelles in the cell; however, they have the ability to fuse, resulting in the formation of interconnected reticular structures. The dynamic changes between these forms correlate with mitochondrial function and mitochondrial health, and consequently, there is a significant scientific interest in uncovering the specific molecular constituents that govern these transitions. Moreover, the specialized mitochondria display a wide array of variable morphologies in their cristae formations. These inner mitochondrial structures are closely associated with the specific functions performed by the mitochondria. In multiple cases, the presence of mitochondrial dysfunction has been linked to male sterility, as it has been observed to cause a range of abnormal spermatogenesis and sperm phenotypes in different species. This review aims to elucidate the dynamic alterations and functions of mitochondria in germ cell development during the spermatogenesis of Drosophila melanogaster.},
	year = {2024},
	eissn = {1422-0067},
	orcid-numbers = {Vedelek, Viktor/0000-0002-0420-8226; Sinka, Rita/0000-0003-4040-4184}
}

@article{MTMT:34770405,
	title = {International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis},
	url = {https://m2.mtmt.hu/api/publication/34770405},
	author = {Chen, Xin and Tsvetkov, Andrey S. and Shen, Han-Ming and Isidoro, Ciro and Ktistakis, Nicholas T. and Linkermann, Andreas and Koopman, Werner J. H. and Simon, Hans-Uwe and Galluzzi, Lorenzo and Luo, Shouqing and Xu, Daqian and Gu, Wei and Peulen, Olivier and Cai, Qian and Rubinsztein, David C. and Chi, Jen-Tsan and Zhang, Donna D. and Li, Changfeng and Toyokuni, Shinya and Liu, Jinbao and Roh, Jong-Lyel and Dai, Enyong and Juhász, Gábor and Liu, Wei and Zhang, Jianhua and Yang, Minghua and Liu, Jiao and Zhu, Ling-Qiang and Zou, Weiping and Piacentini, Mauro and Ding, Wen-Xing and Yue, Zhenyu and Xie, Yangchun and Petersen, Morten and Gewirtz, David A. and Mandell, Michael A. and Chu, Charleen T. and Sinha, Debasish and Eftekharpour, Eftekhar and Zhivotovsky, Boris and Besteiro, Sebastien and Gabrilovich, Dmitry I. and Kim, Do-Hyung and Kagan, Valerian E. and Bayir, Hulya and Chen, Guang-Chao and Ayton, Scott and Luenemann, Jan D. and Komatsu, Masaaki and Krautwald, Stefan and Loos, Ben and Baehrecke, Eric H. and Wang, Jiayi and Lane, Jon D. and Sadoshima, Junichi and Yang, Wan Seok and Gao, Minghui and Munz, Christian and Thumm, Michael and Kampmann, Martin and Yu, Di and Lipinski, Marta M. and Jones, Jace W. and Jiang, Xuejun and Zeh, Herbert J. and Kang, Rui and Klionsky, Daniel J. and Kroemer, Guido and Tang, Daolin},
	doi = {10.1080/15548627.2024.2319901},
	journal-iso = {AUTOPHAGY},
	journal = {AUTOPHAGY},
	unique-id = {34770405},
	issn = {1554-8627},
	abstract = {Macroautophagy/autophagy is a complex degradation process with a dual role in cell death that is influenced by the cell types that are involved and the stressors they are exposed to. Ferroptosis is an iron-dependent oxidative form of cell death characterized by unrestricted lipid peroxidation in the context of heterogeneous and plastic mechanisms. Recent studies have shed light on the involvement of specific types of autophagy (e.g. ferritinophagy, lipophagy, and clockophagy) in initiating or executing ferroptotic cell death through the selective degradation of anti-injury proteins or organelles. Conversely, other forms of selective autophagy (e.g. reticulophagy and lysophagy) enhance the cellular defense against ferroptotic damage. Dysregulated autophagy-dependent ferroptosis has implications for a diverse range of pathological conditions. This review aims to present an updated definition of autophagy-dependent ferroptosis, discuss influential substrates and receptors, outline experimental methods, and propose guidelines for interpreting the results.Abbreviation: 3-MA:3-methyladenine; 4HNE: 4-hydroxynonenal; ACD: accidentalcell death; ADF: autophagy-dependentferroptosis; ARE: antioxidant response element; BH2:dihydrobiopterin; BH4: tetrahydrobiopterin; BMDMs: bonemarrow-derived macrophages; CMA: chaperone-mediated autophagy; CQ:chloroquine; DAMPs: danger/damage-associated molecular patterns; EMT,epithelial-mesenchymal transition; EPR: electronparamagnetic resonance; ER, endoplasmic reticulum; FRET: Forsterresonance energy transfer; GFP: green fluorescent protein;GSH: glutathione;IF: immunofluorescence; IHC: immunohistochemistry; IOP, intraocularpressure; IRI: ischemia-reperfusion injury; LAA: linoleamide alkyne;MDA: malondialdehyde; PGSK: Phen Green (TM) SK;RCD: regulatedcell death; PUFAs: polyunsaturated fatty acids; RFP: red fluorescentprotein;ROS: reactive oxygen species; TBA: thiobarbituricacid; TBARS: thiobarbituric acid reactive substances; TEM:transmission electron microscopy.},
	keywords = {LIPID-PEROXIDATION; MASS-SPECTROMETRY; PROTEIN; CANCER-CELLS; Lipid Peroxidation; IRON; Cell Death; acute kidney injury; transcription factor Nrf2; Lipophagy; ferritinophagy; ferritinophagy; ERASTIN-INDUCED FERROPTOSIS; NONAPOPTOTIC CELL-DEATH},
	year = {2024},
	eissn = {1554-8635},
	orcid-numbers = {Simon, Hans-Uwe/0000-0002-9404-7736; Juhász, Gábor/0000-0001-8548-8874; Ayton, Scott/0000-0002-3479-2427; Lane, Jon D./0000-0002-6828-5888}
}

@article{MTMT:34743202,
	title = {A bipartite NLS motif mediates the nuclear import of Drosophila moesin},
	url = {https://m2.mtmt.hu/api/publication/34743202},
	author = {Kovács, Zoltán and Bajusz, Csaba and Szabó, Anikó and Borkúti, Péter and Vedelek, Balázs and Benke, Reka and Lipinszki, Zoltán and Kristó, Ildikó and Vilmos, Péter},
	doi = {10.3389/fcell.2024.1206067},
	journal-iso = {FRONT CELL DEV BIOL},
	journal = {FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY},
	volume = {12},
	unique-id = {34743202},
	issn = {2296-634X},
	abstract = {The ERM protein family, which consists of three closely related proteins in vertebrates, ezrin, radixin, and moesin (ERM), is an ancient and important group of cytoplasmic actin-binding and organizing proteins. With their FERM domain, ERMs bind various transmembrane proteins and anchor them to the actin cortex through their C-terminal F-actin binding domain, thus they are major regulators of actin dynamics in the cell. ERMs participate in many fundamental cellular processes, such as phagocytosis, microvilli formation, T-cell activation and tumor metastasis. We have previously shown that, besides its cytoplasmic activities, the single ERM protein of Drosophila melanogaster, moesin, is also present in the cell nucleus, where it participates in gene expression and mRNA export. Here we study the mechanism by which moesin enters the nucleus. We show that the nuclear import of moesin is an NLS-mediated, active process. The nuclear localization sequence of the moesin protein is an evolutionarily highly conserved, conventional bipartite motif located on the surface of the FERM domain. Our experiments also reveal that the nuclear import of moesin does not require PIP2 binding or protein activation, and occurs in monomeric form. We propose, that the balance between the phosphorylated and non-phosphorylated protein pools determines the degree of nuclear import of moesin.},
	keywords = {PHOSPHORYLATION; BINDING; LOCALIZATION; IDENTIFICATION; NUCLEUS; STRUCTURAL BASIS; DROSOPHILA; CELL BIOLOGY; ERM PROTEINS; ezrin; moesin; CYTOPLASMIC TAIL; ERM; PIP2; importin; MERLIN; LINKS ACTIN},
	year = {2024},
	eissn = {2296-634X},
	orcid-numbers = {Vedelek, Balázs/0000-0001-6981-0026; Lipinszki, Zoltán/0000-0002-2067-0832}
}

@article{MTMT:34724664,
	title = {PtdIns4p is required for the autophagosomal recruitment of STX17 (syntaxin 17) to promote lysosomal fusion},
	url = {https://m2.mtmt.hu/api/publication/34724664},
	author = {Laczkó-Dobos, Hajnalka and Bhattacharjee, Arindam and Maddali, Asha Kiran and Kincses, András and Abuammar, Hussein and Sebőkné Nagy, Krisztina and Páli, Tibor and Dér, András and Hegedűs, Tamás and Csordás, Gábor and Juhász, Gábor},
	doi = {10.1080/15548627.2024.2322493},
	journal-iso = {AUTOPHAGY},
	journal = {AUTOPHAGY},
	volume = {AiP},
	unique-id = {34724664},
	issn = {1554-8627},
	year = {2024},
	eissn = {1554-8635},
	orcid-numbers = {Páli, Tibor/0000-0003-1649-1097; Hegedűs, Tamás/0000-0002-0331-9629; Csordás, Gábor/0000-0001-6871-6839; Juhász, Gábor/0000-0001-8548-8874}
}

@{MTMT:34723493,
	title = {Mikovírusok azonosítása Rhizopus fajokban},
	url = {https://m2.mtmt.hu/api/publication/34723493},
	author = {Sávai, Gergő and Kartali, Tünde and Benci, Dániel Attila and Patai, Roland and Lipinszki, Zoltán and Vágvölgyi, Csaba and Papp, Tamás},
	booktitle = {Biotechnológiai Szakmai Nap Absztraktfüzet},
	unique-id = {34723493},
	year = {2024},
	orcid-numbers = {Lipinszki, Zoltán/0000-0002-2067-0832; Vágvölgyi, Csaba/0000-0003-0009-7773; Papp, Tamás/0000-0001-8211-5431}
}