TY - JOUR AU - Krasznai, Zoltán AU - Krasznai, Zoárd Tibor AU - Morisawa, M AU - Bazsane, ZK AU - Hernádi, Zoltán AU - Fazekas, Zsolt AU - Trón, Lajos AU - Kormosné, Goda Katalin AU - Márián, Teréz TI - Role of the Na+/Ca2+ exchanger in calcium homeostasis and human sperm motility regulation JF - CELL MOTILITY AND THE CYTOSKELETON J2 - CELL MOTIL CYTOSKEL VL - 63 PY - 2006 IS - 2 SP - 66 EP - 76 PG - 11 SN - 0886-1544 DO - 10.1002/cm.20108 UR - https://m2.mtmt.hu/api/publication/1075258 ID - 1075258 LA - English DB - MTMT ER - TY - JOUR AU - Krasznai, Zoárd Tibor AU - Péliné Szabó, Judit AU - Németh, Enikő AU - Balkay, László AU - Szabó, Gábor AU - Kormosné, Goda Katalin AU - Galuska, László AU - Trón, Lajos AU - Major, T AU - Hernádi, Zoltán TI - Paclitaxel modifies the accumulation of tumor-diagnostic tracers in different ways in P-glycoprotein-positive and negative cancer cells JF - EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES J2 - EUR J PHARM SCI VL - 28 PY - 2006 IS - 3 SP - 249 EP - 256 PG - 8 SN - 0928-0987 DO - 10.1016/j.ejps.2006.02.006 UR - https://m2.mtmt.hu/api/publication/237722 ID - 237722 N1 - Megjegyzés-21999029 Chemicals/CAS: daunorubicin, 12707-28-7, 20830-81-3, 23541-50-6; fluorodeoxyglucose f 18, 63503-12-8; methoxy isobutyl isonitrile technetium tc 99m, 109581-73-9; paclitaxel, 33069-62-4; Antineoplastic Agents, Phytogenic; Fluorodeoxyglucose F18, 63503-12-8; P-Glycoprotein; Paclitaxel, 33069-62-4; Radioactive Tracers; Radiopharmaceuticals; Technetium Tc 99m Sestamibi, 109581-73-9 LA - English DB - MTMT ER - TY - JOUR AU - Márián, Teréz AU - Balkay, László AU - Szabó, Gábor AU - Krasznai, Zoárd Tibor AU - Hernádi, Zoltán AU - Galuska, László AU - Péliné Szabó, Judit AU - Ésik, Olga AU - Trón, Lajos AU - Krasznai, Zoltán TI - Biphasic accumulation kinetics of [Tc-99m]-hexakis-2-methoxyisobutyl isonitrile in tumour cells and its modulation by lipophilic P-glycoprotein ligands JF - EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES J2 - EUR J PHARM SCI VL - 25 PY - 2005 IS - 2-3 SP - 201 EP - 209 PG - 9 SN - 0928-0987 DO - 10.1016/j.ejps.2005.02.010 UR - https://m2.mtmt.hu/api/publication/237727 ID - 237727 N1 - Megjegyzés-22905012 18FDG 99mTc-MIBI uptake LA - English DB - MTMT ER - TY - JOUR AU - Novák, László AU - Molnár, Péter AU - Lengyel, Zsolt AU - Trón, Lajos TI - Does increased (18)FDG uptake reflect malignant transformation of a low-grade glioma? A diagnostic dilemma JF - NEUROLOGY INDIA J2 - NEUROL INDIA VL - 53 PY - 2005 IS - 1 SP - 112 EP - 114 PG - 3 SN - 0028-3886 UR - https://m2.mtmt.hu/api/publication/237726 ID - 237726 LA - English DB - MTMT ER - TY - JOUR AU - Márián, Teréz AU - Balkay, László AU - Trón, Lajos AU - Krasznai, Zoárd Tibor AU - Péliné Szabó, Judit AU - Krasznai, Zoltán TI - Effects of miltefosine on membrane permeability and accumulation of [Tc-99m]-hexakis-2-methoxyisobutyl isonitrile, 2-[F-18]fluoro-2deoxy-D-glucose, daunorubucin and rhodamine123 in multidrug-resistant and sensitive cells JF - EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES J2 - EUR J PHARM SCI VL - 24 PY - 2005 IS - 5 SP - 495 EP - 501 PG - 7 SN - 0928-0987 DO - 10.1016/j.ejps.2005.01.012 UR - https://m2.mtmt.hu/api/publication/237725 ID - 237725 LA - English DB - MTMT ER - TY - JOUR AU - Szavcsur, Péter AU - Gődény, Mária AU - Bajzik, Gábor AU - Lengyel, Erzsébet AU - Repa, Imre AU - Trón, Lajos AU - Boér, András AU - Vincze, Borbála AU - Póti, Zsuzsa AU - Szabolcs, István AU - Ésik, Olga TI - Angiography-proven liver metastases explain low efficacy of lymph node dissections in medullary thyroid cancer patients JF - EUROPEAN JOURNAL OF SURGICAL ONCOLOGY J2 - EUR J SURG ONCOL (EJSO) VL - 31 PY - 2005 IS - 2 SP - 183 EP - 190 PG - 8 SN - 0748-7983 DO - 10.1016/j.ejso.2004.06.011 UR - https://m2.mtmt.hu/api/publication/237724 ID - 237724 N1 - Department of Diagnostic Imaging, National Institute of Oncology, Budapest, Hungary Department of Diagnostic Imaging, University of Kaposvár, Kaposvár, Hungary Department of Radiotherapy, National Institute of Oncology, Ráth György u 7-9, H-1122 Budapest, Hungary PET Center, University of Debrecen, Debrecen, Hungary PET Study Group, Hungarian Academy of Sciences, Debrecen, Hungary Department of Head/Neck Surgery, National Institute of Oncology, Ráth György u 7-9, H-1122 Budapest, Hungary Department of Biochemistry, National Institute of Oncology, Ráth György u 7-9, H-1122 Budapest, Hungary Department of Radiation Oncology, Uzsoki Hospital, Budapest, Hungary Department of Endocrinology, National Health Centre, Budapest, Hungary Department of Oncotherapy, Semmelweis University, Budapest, Hungary Cited By :18 Export Date: 17 July 2023 CODEN: EJSOE Correspondence Address: Ésik, O.; Department of Radiotherapy, Ráth György u 7-9, H-1122 Budapest, Hungary; email: esik@oncol.hu Chemicals/CAS: calcitonin, 12321-44-7, 21215-62-3, 9007-12-9; Calcitonin, 9007-12-9; Tumor Markers, Biological LA - English DB - MTMT ER - TY - JOUR AU - Simon, Alíz AU - Balkay, László AU - Kalinka, Gábor AU - Kerek, A AU - Novák, Dezső AU - Sipos, Attila AU - Végh, János AU - Trón, Lajos AU - Molnár, József TI - High spatial resolution measurement of depth-of-interaction of a PET LSO crystal JF - NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT J2 - NUCL INSTRUM METH A VL - 546 PY - 2005 IS - 1-2 SP - 33 EP - 36 PG - 4 SN - 0168-9002 DO - 10.1016/j.nima.2005.03.036 UR - https://m2.mtmt.hu/api/publication/149502 ID - 149502 N1 - [P18524 ATKI2005/0020] Megjegyzés-22675902 : Equip. Megjegyzés-23616161 T3 Proceedings of the 6th International Workshop on Radiation Imaging Detectors Radiation Imaging Detectors 2004 LA - English DB - MTMT ER - TY - JOUR AU - Póti, Zsuzsa AU - Nemeskéri, Csaba AU - Fekésházy, Attila AU - Sáfrány, Géza AU - Bajzik, Gábor AU - P, Nagy Zoltán AU - Bidlek, Mária AU - Sinkovics, István AU - Udvarhelyi, Nóra AU - Liszkay, Gabriella AU - Repa, Imre AU - Galuska, László AU - Trón, Lajos AU - Mayer, Árpád AU - Ésik, Olga TI - Partial breast irradiation with interstitial 60Co brachytherapy results in frequent grade 3 or 4 toxicity. Evidence based on a 12-year follow-up of 70 patients JF - INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS J2 - INT J RADIAT ONCOL VL - 58 PY - 2004 IS - 4 SP - 1022 EP - 1033 PG - 12 SN - 0360-3016 DO - 10.1016/j.ijrobp.2003.08.013 UR - https://m2.mtmt.hu/api/publication/1241510 ID - 1241510 AB - To investigate the radiation-induced toxicity and cosmesis of brachytherapy (BT) alone in early stage breast cancer.A total of 70 women diagnosed with Stage I or II breast carcinoma participated in a BT study at the Municipal Oncoradiological Center, Uzsoki Hospital, Budapest, Hungary, between November 1987 and June 1992. They had undergone breast-conserving surgery with an unknown surgical margin. The postoperative tumor bed irradiation was performed with interstitial (60)Co sources with an active length of 4 cm, with 10-mm center-to-center spacing arranged in a single plane. The median number of inserted sources was 5 (range, 2-8), with a linear activity of 133-137 MBq/cm at the beginning of the study. The 50 Gy delivered dose at 5 mm from the surface of the (60)Co sources was administered during 10-22 h to the virtual postoperative lumpectomy cavity (i.e., plane). For radiobiologic considerations, the clinical target volume (CTV) was calculated retrospectively with a 10-mm safety margin, resulting in a 72-cm(3) median CTV (range, 36-108 cm(3)) irradiated with a reference dose of 28 Gy. In the assessment of the skin and subcutaneous toxicity, the RTOG late radiation morbidity scoring system was applied. The radiosensitivity of the cultured fibroblasts was determined by clonogenic assay to check whether individual radiosensitivity played a role in the development and course of radiation-induced side-effects.The median follow-up was 12 years (range, 10-15 years). The population of the final study (34 cases) comprised all survivors with tumor-free breasts (27 cases) and patients with breasts erroneously ablated/excised for misinterpreted radiation-induced sequelae (7 patients). A total of 97% of the cohort (33/34) had grade > or =2, and 59% (20/34) had grade > or =3 radiation-induced toxicity. By the end of the follow-up, 85% of the patients experienced Grade > or =2 telangiectasis and 41% had Grade 3 telangiectasis. Eighty-eight percent had fibrosis of some form, and 35% had grade > or =3 fibrosis. Forty-one percent of the cohort displayed fat necrosis, which was always accompanied by Grade > or =3 fibrosis or telangiectasis. The cosmetic results were poor in 50% (17/34) of the patients. The radiosensitivity of the fibroblasts was increased in only 2/24 patients (8% of the investigated cases, in agreement with data published for the general population). Comparisons of our fibrosis prevalence data with those of others allowed an estimate of 0.47 h(-1) for the rate of recovery of DNA damage in the fibroblasts.Interstitial (60)Co BT of the breast tumor bed alone with a limited CTV (median, 72 cm(3)) and a total dose of 28 Gy is associated with a high rate (59%) of grade > or =3 radiation-induced toxicity and a high rate (50%) of poor cosmetic outcome at the end of a median follow-up of 12 years. A relatively high BT dose rate (1.3-2.8 Gy/h) applied during a short overall treatment time (10-22 h) and a possible geographic miss (close to skin implantation) might have contributed to the development of these sequelae. LA - English DB - MTMT ER - TY - JOUR AU - Ésik, Olga AU - Vönöczky, K AU - Lengyel, Zsolt AU - Sáfrány, Géza AU - Trón, Lajos TI - Characteristics of radiogenic lower motor neurone disease, a possible link with a preceding viral infection JF - SPINAL CORD J2 - SPINAL CORD VL - 42 PY - 2004 IS - 2 SP - 99 EP - 105 PG - 7 SN - 1362-4393 DO - 10.1038/sj.sc.3101552 UR - https://m2.mtmt.hu/api/publication/237730 ID - 237730 LA - English DB - MTMT ER - TY - JOUR AU - Novák, László AU - Emri, Miklós AU - Molnár, Péter AU - Balkay, László AU - Lengyel, Zsolt AU - Trón, Lajos TI - Subcortical [18F]fluorodeoxyglucose uptake in lesional epilepsy in patients with intracranial tumour JF - NUCLEAR MEDICINE COMMUNICATIONS J2 - NUCL MED COMMUN VL - 25 PY - 2004 IS - 2 SP - 123 EP - 128 PG - 6 SN - 0143-3636 UR - https://m2.mtmt.hu/api/publication/237729 ID - 237729 LA - English DB - MTMT ER -