TY  - JOUR
AU  - Józsa, Liza
AU  - Siposné Fehér, Pálma
TI  - Kurkumintartalmú ön-nano-emulgeáló rendszerek formulálása gyulladással járó bőrgyógyászati kórképek hatékonyabb kezelésére
JF  - GYÓGYSZERÉSZET
J2  - GYÓGYSZERÉSZET
VL  - 68
PY  - 2024
IS  - 1
SP  - 30
EP  - 36
PG  - 7
SN  - 0017-6036
UR  - https://m2.mtmt.hu/api/publication/34857724
ID  - 34857724
LA  - Hungarian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Otsokolhich, Marko
AU  - Annereau, Maxime
AU  - Bauters, Tiene
AU  - Horváth, László
AU  - Nehal, Chahinez
AU  - Kamal, Sherif
AU  - Vassal, Gilles
AU  - Buraja, Svetlana
TI  - SIOPE and ESOP recommendations for extemporaneous compounding of oral liquid medicine formulations in paediatric oncology
JF  - EJC Paediatric Oncology
J2  - 2730;2919;2735
VL  - 3
PY  - 2024
SP  - 100163
SN  - 2772-610X
DO  - 10.1016/j.ejcped.2024.100163
UR  - https://m2.mtmt.hu/api/publication/34846002
ID  - 34846002
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Moreau, François
AU  - Atamanyuk, Dmytro
AU  - Blaukopf, Markus
AU  - Barath, Marek
AU  - Herczeg, Mihály
AU  - Xavier, Nuno M.
AU  - Monbrun, Jérôme
AU  - Airiau, Etienne
AU  - Henryon, Vivien
AU  - Leroy, Frédéric
AU  - Floquet, Stéphanie
AU  - Bonnard, Damien
AU  - Szabla, Robert
AU  - Brown, Chris
AU  - Junop, Murray S.
AU  - Kosma, Paul
AU  - Gerusz, Vincent
TI  - Potentiating Activity of GmhA Inhibitors on Gram-Negative Bacteria
JF  - JOURNAL OF MEDICINAL CHEMISTRY
J2  - J MED CHEM
VL  - 67
PY  - 2024
IS  - 8
SP  - 6610
EP  - 6623
PG  - 14
SN  - 0022-2623
DO  - 10.1021/acs.jmedchem.4c00037
UR  - https://m2.mtmt.hu/api/publication/34845842
ID  - 34845842
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Farkasinszky, Gergely
AU  - Péliné Szabó, Judit
AU  - Károlyi, Péter
AU  - Rácz, Szilvia
AU  - Dénes, Noémi
AU  - Papp, Tamás
AU  - Király, József
AU  - Szabó, Zsuzsanna
AU  - Kertész, István
AU  - Mező, Gábor
AU  - Halmos, Gábor
AU  - Képes, Zita
AU  - Trencsényi, György
TI  - In Vivo Imaging of Acute Hindlimb Ischaemia in Rat Model: A Pre-Clinical PET Study
JF  - PHARMACEUTICS
J2  - PHARMACEUTICS
VL  - 16
PY  - 2024
IS  - 4
SN  - 1999-4923
DO  - 10.3390/pharmaceutics16040542
UR  - https://m2.mtmt.hu/api/publication/34820368
ID  - 34820368
AB  - Background: To better understand ischaemia-related molecular alterations, temporal changes in angiogenic Aminopeptidase N (APN/CD13) expression and glucose metabolism were assessed with PET using a rat model of peripheral arterial disease (PAD). Methods: The mechanical occlusion of the base of the left hindlimb triggered using a tourniquet was applied to establish the ischaemia/reperfusion injury model in Fischer-344 rats. 2-[18F]FDG and [68Ga]Ga-NOTA-c(NGR) PET imaging performed 1, 3, 5, 7, and 10 days post-ischaemia induction was followed by Western blotting and immunohistochemical staining for APN/CD13 in ischaemic and control muscle tissue extracts. Results: Due to a cellular adaptation to hypoxia, a gradual increase in [68Ga]Ga-NOTA-c(NGR) and 2-[18F]FDG uptake was observed from post-intervention day 1 to 7 in the ischaemic hindlimbs, which was followed by a drop on day 10. Conforming pronounced angiogenic recovery, the NGR accretion of the ischaemic extremities differed significantly from the controls 5, 7, and 10 days after ischaemia induction (p ≤ 0.05), which correlated with the Western blot and immunohistochemical results. No remarkable radioactivity was depicted between the normally perfused hindlimbs of either the ischaemic or the control groups. Conclusions: The PET-based longitudinal assessment of angiogenesis-associated APN/CD13 expression and glucose metabolism during ischaemia may continue to broaden our knowledge on the pathophysiology of PAD.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Bíró, Krisztina
AU  - Ujhelyi, Zoltán
AU  - Schlammadinger, Ágota
AU  - Rázsó, Katalin
AU  - Buchholcz, Gyula
AU  - Boda, Zoltán
TI  - Antitrombin-III-deficites gravidák - kezelési lehetőségek
JF  - GYÓGYSZERÉSZET
J2  - GYÓGYSZERÉSZET
VL  - 68
PY  - 2024
IS  - 2
SP  - 62
EP  - 66
PG  - 5
SN  - 0017-6036
UR  - https://m2.mtmt.hu/api/publication/34813506
ID  - 34813506
LA  - Hungarian
DB  - MTMT
ER  - 

TY  - CONF
AU  - Fésüs, Adina
AU  - Matuz, M
AU  - Hambalek, H
AU  - Ruzsa, R
AU  - Tánczos, B
AU  - Bácskay, I
AU  - Illés, Á
AU  - Benkő, R
TI  - 4CPS-036 Evaluation of the diagnosis and antibiotic prescription pattern in patients hospitalised with urinary tract infections (UTIs)
T2  - Section 4: Clinical pharmacy services
PB  - British Medical Journal Publishing Group
PY  - 2024
SP  - A68.2
EP  - A68
DO  - 10.1136/ejhpharm-2024-eahp.140
UR  - https://m2.mtmt.hu/api/publication/34756237
ID  - 34756237
LA  - English
DB  - MTMT
ER  - 

TY  - CONF
AU  - Fésüs, Adina
AU  - Baluku, P
AU  - Sipos, É
AU  - Somodi, S
AU  - Vaskó, A
AU  - Lekli, I
AU  - Berczi-Kun, E
AU  - Bácskay, I
TI  - 4CPS-035 Impact of antibiotic stewardship programme (ASP) on antibiotic use and clinical outcomes in patients hospitalised with community-acquired pneumonia (CAP): retrospective observational before-after study
T2  - Section 4: Clinical pharmacy services
PB  - British Medical Journal Publishing Group
PY  - 2024
SP  - A68.1
EP  - A68
DO  - 10.1136/ejhpharm-2024-eahp.139
UR  - https://m2.mtmt.hu/api/publication/34756232
ID  - 34756232
LA  - English
DB  - MTMT
ER  - 

TY  - CONF
AU  - Imre, Alexandra
AU  - Kovács, Renátó
AU  - Ibrahim, Al’ Abri
AU  - Nathan, Crook
AU  - Pfliegler, Valter Péter
TI  - Specific high effect mutations in clinical and experimentally evolved Saccharomyces ‘boulardii’ isolates show that genes involved in chemical response might have a role during the adaptation to the human host
T2  - The Allied Genetics Conference 2024 Abstract Book
PY  - 2024
UR  - https://m2.mtmt.hu/api/publication/34753304
ID  - 34753304
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Székvölgyi, Lóránt
TI  - Chromosomal R-loops: who R they?
JF  - BIOLOGIA FUTURA
J2  - BIOL FUTURA
VL  - 3
PY  - 2024
SP  - 1
EP  - 8
PG  - 8
SN  - 2676-8615
DO  - 10.1007/s42977-024-00213-7
UR  - https://m2.mtmt.hu/api/publication/34735372
ID  - 34735372
AB  - R-loops, composed of DNA–RNA hybrids and displaced single-stranded DNA, are known to pose a severe threat to genome integrity. Therefore, extensive research has focused on identifying regulatory proteins involved in controlling R-loop levels. These proteins play critical roles in preventing R-loop accumulation and associated genome instability. Herein I summarize recent knowledge on R-loop regulators affecting R-loop homeostasis, involving a wide array of R-loop screening methods that have enabled their characterization, from forward genetic and siRNA-based screens to proximity labeling and machine learning. These approaches not only deepen our understanding on R-loop formation processes, but also hold promise to find new targets in R-loop dysregulation associated with human pathologies.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Tóth, Balázs István
AU  - Bahar, Bazeli
AU  - Annelies, Janssens
AU  - Lisztes, Erika
AU  - Racskó, Márk
AU  - Kelemen, Balázs
AU  - Herczeg, Mihály
AU  - Nagy, Tamás Milán
AU  - E Kövér, Katalin
AU  - Argha, Mitra
AU  - Attila, Borics
AU  - Bíró, Tamás
AU  - Thomas, Voets
TI  - Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants
JF  - ELIFE
J2  - ELIFE
PY  - 2024
SN  - 2050-084X
UR  - https://m2.mtmt.hu/api/publication/34722559
ID  - 34722559
N1  - preprint DOI-ja: 10.1101/2024.02.01.578392
LA  - English
DB  - MTMT
ER  -