@article{MTMT:34834778,
	title = {Serrated Polyps in Inflammatory Bowel Disease Indicate a Similar Risk of Metachronous Colorectal Neoplasia as in the General Population},
	url = {https://m2.mtmt.hu/api/publication/34834778},
	author = {Medawar, Edgard and Djinbachian, Roupen and Crainic, Ioana Popescu and Safih, Widad and Battat, Robert and Mccurdy, Jeffrey and Lakatos, Péter László and von Renteln, Daniel},
	doi = {10.1007/s10620-024-08456-z},
	journal-iso = {DIGEST DIS SCI},
	journal = {DIGESTIVE DISEASES AND SCIENCES},
	volume = {69},
	unique-id = {34834778},
	issn = {0163-2116},
	year = {2024},
	eissn = {1573-2568},
	pages = {Original Article Published: 03 May 2024},
	orcid-numbers = {Lakatos, Péter László/0000-0002-3948-6488; von Renteln, Daniel/0000-0002-6125-0068}
}

@article{MTMT:34831433,
	title = {Screening of premature ovarian insufficiency associated genes in Hungarian patients with next generation sequencing.},
	url = {https://m2.mtmt.hu/api/publication/34831433},
	author = {Illés, Anett and Pikó, Henriett and Árvai, Kristóf and Donka, Veronika and Szepesi, Olívia and Kósa, János and Lakatos, Péter and Beke, Artúr},
	doi = {10.1186/s12920-024-01873-z},
	journal-iso = {BMC MED GENOMICS},
	journal = {BMC MEDICAL GENOMICS},
	volume = {17},
	unique-id = {34831433},
	issn = {1755-8794},
	abstract = {Premature ovarian insuffiency (POI) is one of the main cause behind infertility. The genetic analysis of POI should be part of the clinical diagnostics, as several genes have been implicated in the genetic background of it. The aim of our study was to analyse the genetic background of POI in a Hungarian cohort.The age of onset was between 15 and 39 years. All patients had the 46,XX karyotype and they were prescreened for the most frequent POI associated FMR1 premutation. To identify genetic alterations next-generation sequencing (NGS) of 31 genes which were previously associated to POI were carried out in 48 unrelated patients from Hungary.Monogenic defect was identified in 16.7% (8 of 48) and a potential genetic risk factor was found in 29.2% (14 of 48) and susceptible oligogenic effect was described in 12.5% (6 of 48) of women with POI using the customized targeted panel sequencing. The genetic analysis identified 8 heterozygous damaging and 4 potentially damaging variants in POI-associated genes. Further 10 potential genetic risk factors were detected in seven genes, from which EIF2B and GALT were the most frequent. These variants were related to 15 genes: AIRE, ATM, DACH2, DAZL, EIF2B2, EIF2B4, FMR1, GALT, GDF9, HS6ST2, LHCGR, NOBOX, POLG, USP9X and XPNPEP2. In six cases, two or three coexisting damaging mutations and risk variants were identified.POI is characterized by heterogenous phenotypic features with complex genetic background that contains increasing number of genes. Deleterious variants, which were detected in our cohort, related to gonadal development (oogenesis and folliculogenesis), meiosis and DNA repair, hormonal signaling, immune function, and metabolism which were previously associated with the POI phenotype. This is the first genetic epidemiology study targeting POI associated genes in Hungary. The frequency of variants in different POI associated genes were similar to the literature, except EIF2B and GALT. Both of these genes potential risk factor were detected which could influence the phenotype, although it is unlikely that they can be responsible for the development of the disease by themselves. Advances of sequencing technologies make it possible to aid diagnostics of POI Since individual patients show high phenotypic variance because of the complex network controlling human folliculogenesis. Comprehensive NGS screening by widening the scope to genes which were previously linked to infertility may facilitate more accurate, quicker and cheaper genetic diagnoses for POI. The investigation of patient's genotype could support clinical decision-making process and pave the way for future clinical trials and therapies.},
	keywords = {infertility; Hungarian; Next generation sequencing; NGS; Premature ovarian insufficiency; POI; PoF},
	year = {2024},
	eissn = {1755-8794},
	orcid-numbers = {Illés, Anett/0000-0001-5351-9015; Pikó, Henriett/0000-0002-3579-5451; Árvai, Kristóf/0000-0001-8774-937X; Lakatos, Péter/0000-0002-7652-3671; Beke, Artúr/0000-0002-6826-7751}
}

@article{MTMT:34826851,
	title = {Treatment of type 2 diabetes mellitus in the elderly – Special considerations},
	url = {https://m2.mtmt.hu/api/publication/34826851},
	author = {Gadó, Klára and Tabák, Ádám and Vingender, István and Domján, Gyula and Bednárikné Dörnyei, Gabriella},
	doi = {10.1556/2060.2024.00317},
	journal-iso = {PHYSIOL INT},
	journal = {PHYSIOLOGY INTERNATIONAL},
	volume = {in press},
	unique-id = {34826851},
	issn = {2498-602X},
	abstract = {Type 2 diabetes is a frequent chronic disease. Given its strong positive association with older age, it is a significant public health issue in elderly populations. Furthermore, the aging of the population, driven by increasing life expectancy in high and middle-income countries leads to an increasing prevalence of diabetes.},
	year = {2024},
	eissn = {2677-0164},
	orcid-numbers = {Gadó, Klára/0000-0003-2253-5826; Tabák, Ádám/0000-0002-6234-3936; Domján, Gyula/0000-0003-0722-1538; Bednárikné Dörnyei, Gabriella/0000-0001-7007-6252}
}

@article{MTMT:34825468,
	title = {Incident Cancer Risk in Patients with Incident Type 2 Diabetes Mellitus in Hungary (Part 1)},
	url = {https://m2.mtmt.hu/api/publication/34825468},
	author = {Abonyi-Tóth, Zsolt and Rokszin, György Aurél and Bajcsayné Fábián, Ibolya and Kiss, Zoltán and Jermendy, György and Kempler, Péter and Lengyel, Csaba Attila and Wittmann, István and Molnár, Gergő Attila and Sütő, Gábor},
	doi = {10.3390/cancers16091745},
	journal-iso = {CANCERS},
	journal = {CANCERS},
	volume = {16},
	unique-id = {34825468},
	abstract = {Abstract
		(1) Background: Patients with type 2 diabetes mellitus (T2DM) are at higher risk of cancer but how these two diseases associate is still debated. The goal of this study was the assessment of the overall incidence of cancer among patients with newly diagnosed T2DM in Hungary. (2) Methods: A nationwide, retrospective, longitudinal study was performed using a Hungarian database. After exclusion of cases of age < 18 years, with gestational diabetes, with polycystic ovary syndrome, and with type 1 and prevalent type 2 diabetes mellitus, the incident T2DM (approx. 50,000 cases yearly) and for comparison, the diabetes-free Hungarian adult population (approx. 7,000,000 cases yearly) was included in the study. The primary endpoints were the overall and site-specific incidence and annual percentage change of the incidence of cancer in both populations. (3) Results: The overall incidence of cancer in patients amounted to 29.4/1000 and 6.6/1000 with or without T2DM, respectively, and the OR (95%CI) of cancer of the T2DM group was 4.32 (4.14–4.53), p < 0.0001. The risk of having cancer was age dependent. The incidence of cancer was declining in the non-diabetic but was unchanged in the T2DM population. The average lag time of diagnosing cancer after the detection of T2DM was 3.86 months. (4) Conclusions: Incident T2DM is associated with a significantly higher overall risk of incident cancer, with a reverse correlation of age. Newly registered T2DM patients were suggested to be screened for cancer within 6 months.},
	year = {2024},
	eissn = {2072-6694},
	orcid-numbers = {Abonyi-Tóth, Zsolt/0000-0002-5585-3313; Kiss, Zoltán/0000-0002-4752-8529; Kempler, Péter/0000-0002-6072-8832; Lengyel, Csaba Attila/0000-0002-0434-0067; Molnár, Gergő Attila/0000-0001-6052-5907}
}

@article{MTMT:34823646,
	title = {Sex- and Ethnicity-related Differences in Pheochromocytoma/Paraganglioma},
	url = {https://m2.mtmt.hu/api/publication/34823646},
	author = {Turai, Péter István and Igaz, Péter},
	doi = {10.1210/jendso/bvae070},
	journal-iso = {J ENDOCRINE SOC},
	journal = {JOURNAL OF THE ENDOCRINE SOCIETY},
	volume = {8},
	unique-id = {34823646},
	year = {2024},
	eissn = {2472-1972},
	orcid-numbers = {Turai, Péter István/0000-0003-2765-2351; Igaz, Péter/0000-0003-2192-554X}
}

@{MTMT:34818298,
	title = {Vesebetegség várandós asszonynál},
	url = {https://m2.mtmt.hu/api/publication/34818298},
	author = {Ledó, Nóra},
	booktitle = {Belgyógyászat 1 tantárgyi jegyzet},
	unique-id = {34818298},
	year = {2024},
	pages = {404-409},
	orcid-numbers = {Ledó, Nóra/0000-0002-2439-9218}
}

@{MTMT:34818282,
	title = {Húgyúti infekciók és obstrukciók},
	url = {https://m2.mtmt.hu/api/publication/34818282},
	author = {Ledó, Nóra},
	booktitle = {Belgyógyászat 1 tantárgyi jegyzet},
	unique-id = {34818282},
	year = {2024},
	pages = {397-403},
	orcid-numbers = {Ledó, Nóra/0000-0002-2439-9218}
}

@{MTMT:34818270,
	title = {A vese vascularis betegségei},
	url = {https://m2.mtmt.hu/api/publication/34818270},
	author = {Studinger, Péter},
	booktitle = {Belgyógyászat 1 tantárgyi jegyzet},
	unique-id = {34818270},
	year = {2024},
	pages = {376-379}
}

@{MTMT:34818261,
	title = {Veseelváltozások szisztémás betegségekben},
	url = {https://m2.mtmt.hu/api/publication/34818261},
	author = {Pethő, Ákos},
	booktitle = {Belgyógyászat 1 tantárgyi jegyzet},
	unique-id = {34818261},
	year = {2024},
	pages = {369-375},
	orcid-numbers = {Pethő, Ákos/0000-0001-9776-9841}
}

@{MTMT:34818246,
	title = {Tubulointerstitialis vesebetegségek},
	url = {https://m2.mtmt.hu/api/publication/34818246},
	author = {Studinger, Péter},
	booktitle = {Belgyógyászat 1 tantárgyi jegyzet},
	unique-id = {34818246},
	year = {2024},
	pages = {364-368}
}