TY - JOUR AU - Vajdle, Olga AU - Mutić, Sanja AU - Lazić, Sanja AU - Kónya, Zoltán AU - Guzsvány, Valéria AU - Anojčić, Jasmina TI - Rapid direct cathodic voltammetric determination of insecticide flonicamid by renewable silver-amalgam film electrode JF - INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY J2 - INT J ENVIRON AN CH PY - 2024 PG - 15 SN - 0306-7319 DO - 10.1080/03067319.2022.2054706 UR - https://m2.mtmt.hu/api/publication/32765296 ID - 32765296 LA - English DB - MTMT ER - TY - JOUR AU - Szabó, Yvette AU - Kiss, Márton Attila AU - Kónya, Zoltán AU - Kukovecz, Ákos AU - Pálinkó, István AU - Sipos, Pál Miklós AU - Nagyné Frank, Éva AU - Szabados, Márton TI - Microwave-induced base-catalyzed synthesis of methyl levulinate, a further improvement in dimethyl carbonate-mediated valorization of levulinic acid JF - APPLIED CATALYSIS A-GENERAL J2 - APPL CATAL A-GEN VL - 651 PY - 2023 PG - 9 SN - 0926-860X DO - 10.1016/j.apcata.2022.119020 UR - https://m2.mtmt.hu/api/publication/33558739 ID - 33558739 LA - English DB - MTMT ER - TY - JOUR AU - Khoshroo, Ghazaleh AU - Sápi, András AU - Szenti, Imre AU - Efremova, Anastasiia AU - Bali, Henrik AU - Baán, Kornélia AU - Erdőhelyi, A. AU - Kukovecz, Ákos AU - Kónya, Zoltán TI - Pure Ni-Based and Trimetallic Ni-Co-Fe Catalysts for the Dry Reforming of Methane: Effect of K Promoter and the Calcination Temperature JF - CATALYSIS LETTERS J2 - CATAL LETT VL - 153 PY - 2023 IS - 9 SP - 2755 EP - 2762 PG - 8 SN - 1011-372X DO - 10.1007/s10562-022-04203-z UR - https://m2.mtmt.hu/api/publication/33545469 ID - 33545469 LA - English DB - MTMT ER - TY - JOUR AU - Szabados, Márton AU - Szabados, Tamara AU - Mucsi, Róbert AU - Sápi, András AU - Kónya, Zoltán AU - Kukovecz, Ákos AU - Pálinkó, István AU - Sipos, Pál Miklós TI - Facile preparation of nickel-poor layered double hydroxides from mechanochemically pretreated gibbsite with a variety of interlamellar anions and their use as catalyst precursors for CO2 hydrogenation JF - MATERIALS RESEARCH BULLETIN J2 - MATER RES BULL VL - 157 PY - 2023 PG - 12 SN - 0025-5408 DO - 10.1016/j.materresbull.2022.112010 UR - https://m2.mtmt.hu/api/publication/33082278 ID - 33082278 LA - English DB - MTMT ER - TY - JOUR AU - Kocsis, Marianna AU - Szabados, Márton AU - Ötvös, Sándor Balázs AU - Samu, Gergely Ferenc AU - Fogarassy, Zsolt AU - Pécz, Béla AU - Kukovecz, Ákos AU - Kónya, Zoltán AU - Sipos, Pál Miklós AU - Pálinkó, István AU - Varga, Gábor TI - Selective production of imines and benzimidazoles by cooperative bismuth(III)/transition metal ion catalysis JF - JOURNAL OF CATALYSIS J2 - J CATAL VL - 414 PY - 2022 SP - 163 EP - 178 PG - 16 SN - 0021-9517 DO - 10.1016/j.jcat.2022.09.008 UR - https://m2.mtmt.hu/api/publication/33097696 ID - 33097696 AB - Cooperative Bi(III)/Co(II) and Bi(III)/Mn(II) heterogeneous catalysts have been developed enabling efficient oxidative annulations for preparing both cross-coupled imines and benzimidazoles under ambient conditions in an atom-economic and time-efficient manner, involving ambient air as oxidant and without the need of any other additives. This is the first synergistic Lewis acid/transition metal catalyzed annulation which is potentiated by the interfaces between the building blocks of the catalysts. To achieve our goals, a useful fabrication process has been developed to heterogenize the transition metal ions via strong interactions on well-known Sillèn-type bismuth subcarbonate (bismutite). Their reusability, activity and selectivity as well as water-tolerance have made them potential competitors to effective heterogeneous/homogeneous catalysts reported previously. LA - English DB - MTMT ER - TY - JOUR AU - Igaz, Nóra AU - Bélteky, Péter AU - Kovács, Dávid AU - Papp, Csaba Gergő AU - Rónavári, Andrea AU - Szabó, Diána AU - Gácser, Attila AU - Kónya, Zoltán AU - Csontné Kiricsi, Mónika TI - Functionalized Mesoporous Silica Nanoparticles for Drug-Delivery to Multidrug-Resistant Cancer Cells JF - INTERNATIONAL JOURNAL OF NANOMEDICINE J2 - INT J NANOMED VL - 17 PY - 2022 SP - 3079 EP - 3096 PG - 18 SN - 1176-9114 DO - 10.2147/IJN.S363952 UR - https://m2.mtmt.hu/api/publication/33003489 ID - 33003489 N1 - Department of Biochemistry and Molecular Biology, University of Szeged, Szeged, Hungary Department of Applied and Environmental Chemistry, University of Szeged, Szeged, Hungary Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d’Azur, Inserm, CNRS, Valbonne, France HCEMM-USZ Fungal Pathogens Research Group, Department of Microbiology, University of Szeged, Szeged, Hungary Department of Oto-Rhino-Laryngology and Head & Neck Surgery, Szeged, Hungary Eötvös Loránd Research Network, Reaction Kinetics and Surface Chemistry Research Group, Szeged, Hungary Cited By :8 Export Date: 27 February 2024 Correspondence Address: Kónya, Z.; Department of Applied and Environmental Chemistry, Rerrich square 1, Hungary; email: konya@chem.u-szeged.hu Correspondence Address: Kiricsi, M.; Department of Biochemistry and Molecular Biology, Közép fasor 52, Hungary; email: kiricsim@bio.u-szeged.hu AB - Background: Multidrug resistance is a common reason behind the failure of chemotherapy. Even if the therapy is effective, serious adverse effects might develop due to the low specificity and selectivity of antineoplastic agents. Mesoporous silica nanoparticles (MSNs) are promising materials for tumor-targeting and drug-delivery due to their small size, relatively inert nature, and extremely large specific surfaces that can be functionalized by therapeutic and targeting entities. We aimed to create a fluorescently labeled MSN-based drug-delivery system and investigate their internalization and drug-releasing capability in drug-sensitive MCF-7 and P-glycoprotein-overexpressing multidrug-resistant MCF-7 KCR cancer cells.Methods and Results: To track the uptake and subcellular distribution of MSNs, particles with covalently coupled red fluorescent Rhodamine B (RhoB) were produced (RhoB@MSNs). Both MCF-7 and MCF-7 KCR cells accumulated a significant amount of RhoB@MSNs. The intracellular RhoB@MSN concentrations did not differ between sensitive and multidrug-resistant cells and were kept at the same level even after cessation of RhoB@MSN exposure. Although most RhoB@MSNs resided in the cytoplasm, significantly more RhoB@MSNs co-localized with lysosomes in multidrug-resistant cells compared to sensitive counterparts. To examine the drug-delivery capability of these particles, RhoB@Rho123@MSNs were established, where RhoB-functionalized nanoparticles carried green fluorescent Rhodamine 123 (Rho123) -a P-glycoprotein substrate - as cargo within mesopores. Significantly higher Rho123 fluorescence intensity was detected in RhoB@Rho123@MSN-treated multidrug-resistant cells than in free Rho123-exposed counterparts. The exceptional drug-delivery potential of MSNs was further verified using Mitomycin C (MMC)-loaded RhoB@MSNs (RhoB@MMC@MSNs). Exposures to RhoB@MMC@MSNs significantly decreased the viability not only of drug-sensitive but of multidrug-resistant cells and the elimination of MDR cells was significantly more robust than upon free MMC treatments.Conclusion: The efficient delivery of Rho123 and MMC to multidrug-resistant cells via MSNs, the amplified and presumably prolonged intracellular drug concentration, and the consequently enhanced cytotoxic effects envision the enormous potential of MSNs to defeat multidrug-resistant cancer. LA - English DB - MTMT ER - TY - JOUR AU - Chawla, Harshita AU - Garg, Seema AU - Rohilla, Jyoti AU - Szamosvölgyi, Ákos AU - Efremova, Anastasiia AU - Szenti, Imre AU - Ingole, Pravin Popinand AU - Sápi, András AU - Kónya, Zoltán AU - Chandra, Amrish TI - Visible LED-light driven photocatalytic degradation of organochlorine pesticides (2,4-D & 2,4-DP) by Curcuma longa mediated bismuth vanadate JF - JOURNAL OF CLEANER PRODUCTION J2 - J CLEAN PROD VL - 367 PY - 2022 PG - 14 SN - 0959-6526 DO - 10.1016/j.jclepro.2022.132923 UR - https://m2.mtmt.hu/api/publication/32922861 ID - 32922861 LA - English DB - MTMT ER - TY - JOUR AU - Malik, Ali Shan AU - Bali, Henrik AU - Czirok, Fanni AU - Szamosvölgyi, Ákos AU - Halasi, Gyula AU - Efremova, Anastasiia AU - Šmíd, Břetislav AU - Sápi, András AU - Kukovecz, Ákos AU - Kónya, Zoltán TI - Turning CO2 to CH4 and CO over CeO2 and MCF-17 supported Pt, Ru and Rh nanoclusters – Influence of nanostructure morphology, supporting materials and operating conditions JF - FUEL J2 - FUEL VL - 326 PY - 2022 PG - 12 SN - 0016-2361 DO - 10.1016/j.fuel.2022.124994 UR - https://m2.mtmt.hu/api/publication/32907147 ID - 32907147 LA - English DB - MTMT ER - TY - JOUR AU - Kozma, Gábor AU - Lipták, Kata AU - Deák, Cora AU - Rónavári, Andrea AU - Kukovecz, Ákos AU - Kónya, Zoltán TI - Conversion Study on the Formation of Mechanochemically Synthesized BaTiO3 JF - CHEMISTRY J2 - CHEMISTRY VL - 4 PY - 2022 IS - 2 SP - 592 EP - 602 PG - 11 SN - 2624-8549 DO - 10.3390/chemistry4020042 UR - https://m2.mtmt.hu/api/publication/32893026 ID - 32893026 AB - Mechanochemistry is a method that can cover the energy demand of reaction pathways between solid materials. This requires enough energy to maintain the reactions between the starting materials. This is called “high-energy milling”. In our case, a planetary ball mill provided the required energy. Using the Burgio-equation, the required energy is determinable; the energy released during a single impact of a milling ball (Eb), as well as during the whole milling process (Ecum). The aim of this work was the one-step production of BaTiO3 from BaO and TiO2 starting materials. Whereas during mechanochemical reactions it is possible to produce nanoparticles of up to 10 nm, the essence of this study is to develop the preparation of BaTiO3 with a perovskite structure even without subsequent heat treatment, since sintering at high temperatures is associated with a rapid increase in the size of the particles. By describing the synthesis parameters and their energy values (Eb and Ecum), it is possible to transpose experimental conditions, so that in the case of other types of planetary ball mills or grinding vessel made of other materials, the results can be used. In this study, the mechanical treatment was carried out with a Fritsch Pulverisette-6 planetary ball mill and the transformation of the starting materials was investigated by X-ray diffractometric, Raman and Energy-dispersive X-ray spectroscopic, and transmission electron microscopic measurements. LA - English DB - MTMT ER - TY - JOUR AU - Szamosvölgyi, Ákos AU - Rajkumar, T. AU - Sápi, András AU - Szenti, Imre AU - Ábel, Marietta AU - Gomez Perez, Juan Fernando AU - Baán, Kornélia AU - Fogarassy, Zsolt AU - Dodony, Erzsébet AU - Pécz, Béla AU - Garg, Seema AU - Kiss, János AU - Kukovecz, Ákos AU - Kónya, Zoltán TI - Interfacial Ni active sites strike solid solutional counterpart in CO2 hydrogenation JF - ENVIRONMENTAL TECHNOLOGY & INNOVATION J2 - ENVIRON TECH INNOV VL - 27 PY - 2022 PG - 12 SN - 2352-1864 DO - 10.1016/j.eti.2022.102747 UR - https://m2.mtmt.hu/api/publication/32891371 ID - 32891371 LA - English DB - MTMT ER -