TY - JOUR AU - Szekanecz, Zoltán AU - Kacsándi, Dorottya AU - Soós, Boglárka TI - A rheumatoid arthritis etiopatogenezise - újdonságok JF - IMMUNOLÓGIAI SZEMLE J2 - IMMUNOLÓGIAI SZEMLE VL - 16 PY - 2024 IS - 1 SP - 4 EP - 14 PG - 11 SN - 2061-0203 UR - https://m2.mtmt.hu/api/publication/34831051 ID - 34831051 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Szekanecz, Zoltán TI - A JAK-gátlók alkalmazásának jövőbeli lehetőségei krónikus gyulladásos kórképekben JF - ORVOSTOVÁBBKÉPZŐ SZEMLE J2 - ORVOSTOVÁBBKÉPZŐ SZLE PY - 2024 SN - 1218-2583 UR - https://m2.mtmt.hu/api/publication/34829474 ID - 34829474 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Geetha, Duvuru AU - Dua, Anisha AU - Yue, Huibin AU - Springer, Jason AU - Salvarani, Carlo AU - Jayne, David AU - Merkel, Peter AU - Szűcs, Gabriella TI - Efficacy and safety of avacopan in patients with ANCA-associated vasculitis receiving rituximab in a randomised trial JF - ANNALS OF THE RHEUMATIC DISEASES J2 - ANN RHEUM DIS VL - 83 PY - 2024 IS - 2 SP - 223 EP - 232 PG - 10 SN - 0003-4967 DO - 10.1136/ard-2023-224816 UR - https://m2.mtmt.hu/api/publication/34820283 ID - 34820283 LA - English DB - MTMT ER - TY - JOUR AU - Paragh, György AU - Harangi, Mariann TI - Hyperlipoproteinaemiák és kezelési lehetőségeik JF - ORVOSTOVÁBBKÉPZŐ SZEMLE J2 - ORVOSTOVÁBBKÉPZŐ SZLE VL - 31 PY - 2024 IS - 3 SP - 61 EP - 68 PG - 8 SN - 1218-2583 UR - https://m2.mtmt.hu/api/publication/34817301 ID - 34817301 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Paragh, György AU - Harangi, Mariann AU - Bársony, Gábor AU - Mazzag, Bálint AU - Együd, Ferenc TI - Milyen volt a hyperlipidaemia kezelése és a kezelőorvosok attitűdje 2022-ben? JF - METABOLIZMUS J2 - METABOLIZMUS VL - 22 PY - 2024 IS - 1 SP - 26 EP - 32 PG - 7 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/34817266 ID - 34817266 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Paragh, György AU - Zilahi, Péter AU - Szentimrei, Réka AU - Lőrincz, Hajnalka AU - Kolozsvári, László AU - Harangi, Mariann TI - Milyen kezelési lehetőségeink vannak a magas lipoprotein(a) csökkentésére? JF - METABOLIZMUS J2 - METABOLIZMUS VL - 22 PY - 2024 IS - 1 SP - 16 EP - 22 PG - 7 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/34817183 ID - 34817183 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Szekanecz, Zoltán AU - Szamosi, Szilvia AU - Benkő, Szilvia AU - Szűcs, Gabriella TI - Monogénesen öröklődő és szerzett autoinflammatoricus betegségek JF - ORVOSI HETILAP J2 - ORV HETIL VL - 165 PY - 2024 IS - 18 SP - 683 EP - 697 PG - 15 SN - 0030-6002 UR - https://m2.mtmt.hu/api/publication/34797501 ID - 34797501 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Gulyás, Anita AU - Pinczés, László Imre AU - Mátyus, János AU - Végh, Edit AU - Bedekovics, Judit AU - Tóth, Judit AU - Barna, Sándor Kristóf AU - Hunya, Zsolt AU - Szabó, Imre Lőrinc AU - Gazdag, Annamária AU - Illés, Árpád AU - Magyari, Ferenc TI - Case report: Targeted treatment strategies for Erdheim-Chester disease JF - FRONTIERS IN ONCOLOGY J2 - FRONT ONCOL VL - 14 PY - 2024 SN - 2234-943X DO - 10.3389/fonc.2024.1305518 UR - https://m2.mtmt.hu/api/publication/34794833 ID - 34794833 LA - English DB - MTMT ER - TY - JOUR AU - Major, Tamás AU - Nagy, Gábor AU - Szabó, Judit AU - Mózes, Huba AU - Szűcs, Gabriella AU - Szekanecz, Zoltán AU - Szamosi, Szilvia TI - Granulomatosis with polyangiitis or its mimic? A case report JF - JOURNAL OF INTERNATIONAL MEDICAL RESEARCH J2 - J INT MED RES VL - 52 PY - 2024 IS - 4 SP - 1 EP - 8 PG - 8 SN - 0300-0605 DO - 10.1177/03000605241237876 UR - https://m2.mtmt.hu/api/publication/34788385 ID - 34788385 AB - Differentiation between granulomatosis with polyangiitis (GPA) limited to the upper airways and cocaine-induced midline destructive lesion (CIMDL) may be particularly difficult because of their common histopathologic features and antineutrophil cytoplasmic antibody (ANCA) profiles. We herein present a case involving a young woman with an initial diagnosis of GPA based on upper and lower airway manifestations and constitutional symptoms, histopathologic evidence of granulomas, a positive cytoplasmic ANCA indirect immunofluorescent test result, and proteinase 3 positivity by enzyme-linked immunosorbent assay (ELISA). CIMDL was confirmed based on the appearance of a hard palate perforation, positivity for methylecgonine on urine toxicology, a positive perinuclear ANCA indirect immunofluorescent test result, and subsequent human neutrophil elastase (HNE) ANCA positivity by ELISA. Finally, based on the coexistence of CIMDL, constitutional symptoms, and lower airway manifestations, the diagnosis was modified to cocaine-induced GPA mimic. Urine toxicology for cocaine and HNE ELISA are indicated in young patients with GPA who develop limited airway disease to check for the presence of CIMDL and cocaine-/levamisole-induced ANCA-associated vasculitis. Continued abstinence from cocaine is the first-choice therapy for both CIMDL and cocaine-induced GPA mimic. LA - English DB - MTMT ER - TY - JOUR AU - Lodin, Karin AU - Espinosa-Ortega, Fabricio AU - Dastmalchi, Maryam AU - Vencovsky, Jiri AU - Andersson, Helena AU - Chinoy, Hector AU - Lilleker, James B. AU - Shinjo, Samuel Katsuyuki AU - Maurer, Britta AU - Griger, Zoltán AU - Ceribelli, Angela AU - Torres-Ruiz, Jiram AU - Mercado, Mónica Vázquez-Del AU - Leonard, Dag AU - Alexanderson, Helene AU - Lundberg, Ingrid TI - Patient global assessment and inflammatory markers in patients with idiopathic inflammatory myopathies: a longitudinal study JF - SEMINARS IN ARTHRITIS AND RHEUMATISM J2 - SEMIN ARTHRITIS RHEU VL - 65 PY - 2024 SP - 1 EP - 10 PG - 10 SN - 0049-0172 DO - 10.1016/j.semarthrit.2024.152379 UR - https://m2.mtmt.hu/api/publication/34775662 ID - 34775662 AB - Aim : To explore if patient global assessment (PGA) is associated with inflammation over time and if associations are explained by other measures of disease activity and function in patients with idiopathic inflammatory myopathies (IIM). Methods : PGA and systemic inflammatory markers prospectively collected over five years were retrieved from the International MyoNet registry for 1200 patients with IIM. Associations between PGA, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and creatine kinase (CK) were analysed using mixed models. Mediation analysis was used to test if the association between PGA and inflammatory markers during the first year of observation could be explained by measures of disease activity and function. Results : PGA improved, and inflammatory markers decreased during the first year of observation. In the mixed models, high levels of inflammatory markers were associated with worse PGA in both men and women across time points during five years of observation. In men, but not in women, the association between elevated ESR, CRP and poorer PGA was explained by measures of function and disease activity. With a few exceptions, the association between improved PGA and reduced inflammatory markers was partially mediated by improvements in all measures of function and disease activity. Conclusion : Increased levels of systemic inflammation are associated with poorer PGA in patients with IIM. In addition to known benefits of lowered inflammation, these findings emphasize the need to reduce systemic inflammation to improve subjective health in patients with IIM. Furthermore, the results demonstrate the importance of incorporating PGA as an outcome measure in clinical practice and clinical trials. LA - English DB - MTMT ER -