TY - JOUR AU - Bicskó, Ráhel Réka AU - Illés, Árpád AU - Hevessy Zsuzsanna, Dóra AU - Ivády, Gergely AU - Kerekes, György AU - Méhes, Gábor AU - Csépány, Tünde AU - Gergely, Lajos TI - Eculizumab Treatment of Massive Hemolysis Occurring in a Rare Co-Existence of Paroxysmal Nocturnal Hemoglobinuria and Myasthenia Gravis JF - HEMATOLOGY REPORTS J2 - HEMATOL REP VL - 16 PY - 2024 IS - 2 SP - 255 EP - 259 PG - 5 SN - 2038-8322 DO - 10.3390/hematolrep16020025 UR - https://m2.mtmt.hu/api/publication/34818887 ID - 34818887 AB - The co-occurrence of myasthenia gravis (MG) and paroxysmal nocturnal hemoglobinuria (PNH) is rare; only one case has been published so far. We report a 63-year-old Caucasian female patient who was diagnosed with MG at the age of 43. Thymoma was also detected, and so it was surgically resected, which resulted in reasonable disease control for nearly 20 years. Slight hemolysis began to emerge, and then myasthenia symptoms progressed, so immunosuppressive therapy was started. Due to progressive disease and respiratory failure, the patient underwent plasmapheresis, and ventilatory support was stopped. Marked hemolysis was present, and diagnostic tests confirmed PNH with type III PNH cells. Her myasthenia symptoms aggravated, mechanical ventilation had to be started again, and due to the respiratory acidosis, massive hemolysis occurred. After two plasmapheresis sessions, the patient received eculizumab at 600 mg, resulting in prompt hemolysis control. After the second dose of the treatment, the patient was extubated. Still, due to their inability to cough, she developed another respiratory failure and pneumonia–sepsis, resulting in the patient’s death. This case highlights the rare association between these two serious diseases and similar immune-mediated pathophysiology mechanisms involving the complement system. LA - English DB - MTMT ER - TY - JOUR AU - Gulyás, Anita AU - Pinczés, László Imre AU - Mátyus, János AU - Végh, Edit AU - Bedekovics, Judit AU - Tóth, Judit AU - Barna, Sándor Kristóf AU - Hunya, Zsolt AU - Szabó, Imre Lőrinc AU - Gazdag, Annamária AU - Illés, Árpád AU - Magyari, Ferenc TI - Case report: Targeted treatment strategies for Erdheim-Chester disease JF - FRONTIERS IN ONCOLOGY J2 - FRONT ONCOL VL - 14 PY - 2024 SN - 2234-943X DO - 10.3389/fonc.2024.1305518 UR - https://m2.mtmt.hu/api/publication/34794833 ID - 34794833 LA - English DB - MTMT ER - TY - JOUR AU - Bedekovics, Judit AU - Madarász, Kristóf AU - Mokánszki, Attila AU - Molnár, Sarolta AU - Mester, Ágnes AU - Miltényi, Zsófia AU - Méhes, Gábor TI - Exploring p53 protein expression and its link to TP53 mutation in myelodysplasia‐related malignancies—Interpretive challenges and potential field of applications JF - HISTOPATHOLOGY J2 - HISTOPATHOLOGY PY - 2024 SN - 0309-0167 DO - 10.1111/his.15185 UR - https://m2.mtmt.hu/api/publication/34773648 ID - 34773648 LA - English DB - MTMT ER - TY - JOUR AU - Stružinská, Ivana AU - Hájková, Nikola AU - Hojný, Jan AU - Krkavcová, Eva AU - Michálková, Romana AU - Bui, Quang Hiep AU - Matěj, Radoslav AU - Laco, Jan AU - Drozenová, Jana AU - Fabian, Pavel AU - Škapa, Petr AU - Špůrková, Zuzana AU - Cibula, David AU - Frühauf, Filip AU - Jirásek, Tomáš AU - Zima, Tomáš AU - Méhes, Gábor AU - Kendall Bártů, Michaela AU - Němejcová, Kristýna AU - Dundr, Pavel TI - Somatic Genomic and Transcriptomic Characterization of Primary Ovarian Serous Borderline Tumors and Low-Grade Serous Carcinomas JF - JOURNAL OF MOLECULAR DIAGNOSTICS J2 - J MOL DIAGN VL - 26 PY - 2024 IS - 4 SP - 257 EP - 266 PG - 10 SN - 1525-1578 DO - 10.1016/j.jmoldx.2023.12.004 UR - https://m2.mtmt.hu/api/publication/34725533 ID - 34725533 LA - English DB - MTMT ER - TY - JOUR AU - P. Szabó, Réka AU - Kóka-Bujáki, Boglárka AU - File, Ibolya AU - Markóth, Csilla AU - Hutkai, Dávid AU - Mátyus, János AU - Asztalos, László AU - Nemes, Balázs AU - Bidiga, László AU - Balla, József TI - Vesetranszplantáltak utógondozásának gyakorlata tanszékünkön JF - HYPERTONIA ÉS NEPHROLOGIA J2 - HYPERTONIA NEPHROLOGIA VL - 27 PY - 2023 IS - Suppl_2 SP - 38 SN - 1418-477X UR - https://m2.mtmt.hu/api/publication/34784321 ID - 34784321 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Tornai, Dávid AU - Balogh, Boglárka AU - Csillag, Anikó AU - Budai, András AU - Kiss, Andras AU - Antal-Szalmás, Péter AU - Méhes, Gábor AU - Barath, Lukacs AU - Tornai, Tamas AU - Tornai, István AU - Vitális, Zsuzsanna AU - Sipeki, Nóra AU - Kováts, Patrícia AU - Trebicka, Jonel AU - Papp, Mária TI - Serum villin-1 level-a tell-tale sign of gut barrier failure in patients with cirrhosis and acute decompensation JF - JOURNAL OF HEPATOLOGY J2 - J HEPATOL VL - 78 PY - 2023 IS - S1 SP - S25 EP - S25 SN - 0168-8278 UR - https://m2.mtmt.hu/api/publication/34768194 ID - 34768194 LA - English DB - MTMT ER - TY - JOUR AU - Dull, Katalin AU - Lénárt, Kinga AU - Dajnoki, Zsolt AU - Póliska, Szilárd AU - Szegedi, Andrea AU - Törőcsik, Dániel AU - Hendrik, Zoltán TI - Barrier function related genes and proteins are altered in acne involved skin JF - JOURNAL OF INVESTIGATIVE DERMATOLOGY J2 - J INVEST DERMATOL VL - 143 PY - 2023 IS - 5 SP - S122 EP - S122 SN - 0022-202X UR - https://m2.mtmt.hu/api/publication/34738421 ID - 34738421 LA - English DB - MTMT ER - TY - JOUR AU - Gaspar, Krisztian AU - Somogyi, Orsolya AU - Dajnoki, Zsolt AU - Szabó, Lilla AU - Hendrik, Zoltán AU - Zouboulis, Christos C. AU - Dócs, Klaudia AU - Szűcs, Péter AU - Dull, Katalin AU - Törőcsik, Dániel AU - Kapitány, Anikó AU - Szegedi, Andrea TI - Skin barrier alterations are not a characteristic feature of hidradenitis suppurativa JF - EXPERIMENTAL DERMATOLOGY J2 - EXP DERMATOL VL - 32 PY - 2023 IS - Supplement_1 SP - 45 EP - 45 PG - 1 SN - 0906-6705 UR - https://m2.mtmt.hu/api/publication/34693588 ID - 34693588 LA - English DB - MTMT ER - TY - JOUR AU - Hudák, Lilla AU - Nagy, A. AU - Perjesi-Kiss, B. AU - Fulesdi, Z. AU - Busi, B. AU - Nagy, K. AU - Méhes, Gábor AU - Oláh, László AU - Csiba, László TI - Hemorrhagic transformation and non-CNS complications after iv. thrombolysis: a brain and body autopsy study JF - EUROPEAN JOURNAL OF NEUROLOGY J2 - EUR J NEUROL VL - 30 PY - 2023 IS - Supplement_1 SP - 455 EP - 455 PG - 1 SN - 1351-5101 UR - https://m2.mtmt.hu/api/publication/34693306 ID - 34693306 LA - English DB - MTMT ER - TY - JOUR AU - Köröskényi, L AU - Nagy, BE AU - Aradi, Z AU - Szántó, Antónia AU - Bedekovics, Judit AU - Tóth, L AU - Steiber, Zita AU - Nagy, VE AU - Erdei, A TI - NERVUS OPTICUS KOMPRESSZIÓVAL JÁRÓ ENDOKRIN ORBITOPATHIÁT „UTÁNZÓ” VASCULITIS – ESETISMERTETÉS JF - MAGYAR BELORVOSI ARCHIVUM J2 - MBA VL - 76 PY - 2023 IS - 5-6 SP - 318 EP - 318 PG - 1 SN - 0133-5464 UR - https://m2.mtmt.hu/api/publication/34565118 ID - 34565118 LA - Hungarian DB - MTMT ER -