@article{MTMT:34831542,
	title = {Potential interactive effect of positive expectancy violation and sleep on memory consolidation in dogs},
	url = {https://m2.mtmt.hu/api/publication/34831542},
	author = {Reicher, Vivien and Kovács, Tímea and Csibra, Barbara and Gácsi, Márta},
	doi = {10.1038/s41598-024-60166-8},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {14},
	unique-id = {34831542},
	issn = {2045-2322},
	abstract = {In dogs, as in humans, both emotional and learning pretreatment affect subsequent behaviour and sleep. Although learning often occurs in an emotional-social context, the emotion-learning interplay in such context remain mainly unknown. Aims were to assess the effects of Controlling versus Permissive (emotional factors) training (learning factors) styles on dogs’ behaviour, learning performance, and sleep. Family dogs ( N  = 24) participated in two command learning sessions employing the two training styles with each session followed by assessment of learning performance, a 2-h-long non-invasive sleep EEG measurement, and a retest of learning performance. Pre- to post-sleep improvement in learning performance was evident in dogs that received the Permissive training during the second learning session, indicating that dogs that experienced a more rewarding situation than expected (positive expectancy violation) during the second training session showed improved learning success after their afternoon sleep. These results possibly indicate an interactive effect of expectancy violation and sleep on enhancing learning.},
	year = {2024},
	eissn = {2045-2322},
	orcid-numbers = {Gácsi, Márta/0000-0003-3080-7545}
}

@article{MTMT:34821684,
	title = {Emergence of keystone individuals in the social networks of the ant Camponotus fellah},
	url = {https://m2.mtmt.hu/api/publication/34821684},
	author = {Kovács, Bálint and Jordán, F.},
	doi = {10.1007/s00040-024-00963-6},
	journal-iso = {INSECT SOC},
	journal = {INSECTES SOCIAUX},
	unique-id = {34821684},
	issn = {0020-1812},
	abstract = {Community ecology and sociobiology share a number of problems (e.g. understanding part-to-whole relationships), so sharing methods may be beneficial. In this paper, we re-analyze a large social network database for Camponotus fellah ants, from the perspective of keystone individuals, based on methods developed in community ecology. We study different network types for six colonies, over a time series of 10 days. These include the total network of weighted interactions, the subnetworks for the castes and the subnetworks for Queen-linked and Queen-independent individuals. We perform time-independent (i.e. average values) and temporal (i.e. trends) analyses. The most commonly used global network metrics showed high variability in time but no clear trends. Yet, the variability of a network centrality index (topological importance, TI), developed earlier in community ecology, shows clear increase in each colony over time, suggesting the emergence of keystone individuals as a general tendency in all studied ant colonies.},
	year = {2024},
	eissn = {1420-9098},
	orcid-numbers = {Jordán, F./0000-0002-0224-6472}
}

@article{MTMT:34787582,
	title = {Responses in the breeding parameters of the collared flycatcher to the changing climate},
	url = {https://m2.mtmt.hu/api/publication/34787582},
	author = {Laczi, Miklós and Sarkadi, Fanni and Herényi, Márton and Nagy, Gergely and Hegyi, Gergely and Jablonszky, Mónika and Könczey, Réka and Krenhardt, Katalin and Markó, Gábor and Rosivall, Balázs and Szász, Eszter and Szöllősi, Eszter and Tóth, László and Zsebők, Sándor and Török, János},
	doi = {10.1016/j.scitotenv.2024.171945},
	journal-iso = {SCI TOTAL ENVIRON},
	journal = {SCIENCE OF THE TOTAL ENVIRONMENT},
	volume = {926},
	unique-id = {34787582},
	issn = {0048-9697},
	year = {2024},
	eissn = {1879-1026},
	orcid-numbers = {Laczi, Miklós/0000-0001-9235-2553; Sarkadi, Fanni/0000-0001-8732-972X; Herényi, Márton/0000-0003-4457-9096; Nagy, Gergely/0000-0002-0943-2876; Hegyi, Gergely/0000-0002-4906-3550; Krenhardt, Katalin/0000-0002-3753-1353; Markó, Gábor/0000-0003-1351-4070; Rosivall, Balázs/0000-0002-0732-1160; Szász, Eszter/0000-0002-9810-2085; Szöllősi, Eszter/0000-0003-2913-2894; Zsebők, Sándor/0000-0003-4463-4753; Török, János/0000-0002-4799-5522}
}

@article{MTMT:34777528,
	title = {New Salicylanilide Derivatives and Their Peptide Conjugates as Anticancer Compounds: Synthesis, Characterization, and In Vitro Effect on Glioblastoma},
	url = {https://m2.mtmt.hu/api/publication/34777528},
	author = {Horváth, Lilla and Biri-Kovács, Beáta and Baranyai, Zsuzsa and Stipsicz, Bence András and Méhes, Előd and Jezsó, Bálint and Krátký, Martin and Vinšová, Jarmila and Bősze, Szilvia},
	doi = {10.1021/acsomega.3c05727},
	journal-iso = {ACS OMEGA},
	journal = {ACS OMEGA},
	volume = {9},
	unique-id = {34777528},
	issn = {2470-1343},
	year = {2024},
	eissn = {2470-1343},
	pages = {16927-16948},
	orcid-numbers = {Biri-Kovács, Beáta/0000-0001-5803-9969; Méhes, Előd/0000-0003-2697-907X; Jezsó, Bálint/0000-0002-1306-4797}
}

@article{MTMT:34774857,
	title = {Food density drives diet shift of the invasive mysid shrimp, Limnomysis benedeni},
	url = {https://m2.mtmt.hu/api/publication/34774857},
	author = {Rani, Varsha and Horváth, Zsófia and Nejstgaard, Jens C. and Fierpasz, Ádám and Pálffy, Károly and Vad, Csaba Ferenc},
	doi = {10.1002/ece3.11202},
	journal-iso = {ECOL EVOL},
	journal = {ECOLOGY AND EVOLUTION},
	volume = {14},
	unique-id = {34774857},
	issn = {2045-7758},
	abstract = {Understanding the diet preferences and food selection of invasive species is crucial to better predict their impact on community structure and ecosystem functioning. Limnomysis benedeni , a Ponto‐Caspian invasive mysid shrimp, is one of the most successful invaders in numerous European river and lake ecosystems. While existing studies suggest potentially strong trophic impact due to high predation pressure on native plankton communities, little is known of its food selectivity between phyto‐ and zooplankton, under different food concentrations. Here, we therefore investigated the feeding selectivity of L .  benedeni on two commonly occurring prey organisms in freshwaters, the small rotifer zooplankton Brachionus calyciflorus together with the microphytoplankton Cryptomonas sp. present in increasing densities. Our results demonstrated a clear shift in food selection, with L. benedeni switching from B. calyciflorus to Cryptomonas sp. already when the two prey species were provided in equal biomasses. Different functional responses were observed for the two food types, indicating somewhat different foraging mechanisms for each food type. These findings provide experimental evidence on the feeding flexibility of invasive mysid shrimps and potential implications for trophic interactions in invaded ecosystems.},
	year = {2024},
	eissn = {2045-7758},
	orcid-numbers = {Horváth, Zsófia/0000-0003-2857-1094; Nejstgaard, Jens C./0000-0003-1236-0647; Vad, Csaba Ferenc/0000-0003-4744-0698}
}

@article{MTMT:34773735,
	title = {Morphological Changes Induced by TKS4 Deficiency Can Be Reversed by EZH2 Inhibition in Colorectal Carcinoma Cells},
	url = {https://m2.mtmt.hu/api/publication/34773735},
	author = {Jacksi, Mevan Fahmi Sami and Schad, Eva and Tantos, Agnes},
	doi = {10.3390/biom14040445},
	journal-iso = {BIOMOLECULES},
	journal = {BIOMOLECULES},
	volume = {14},
	unique-id = {34773735},
	issn = {2218-273X},
	abstract = {Background: The scaffold protein tyrosine kinase substrate 4 (TKS4) undergoes tyrosine phosphorylation by the epidermal growth factor receptor (EGFR) pathway via Src kinase. The TKS4 deficiency in humans is responsible for the manifestation of a genetic disorder known as Frank–Ter Haar syndrome (FTHS). Based on our earlier investigation, the absence of TKS4 triggers migration, invasion, and epithelial–mesenchymal transition (EMT)-like phenomena while concurrently suppressing cell proliferation in HCT116 colorectal carcinoma cells. This indicates that TKS4 may play a unique role in the progression of cancer. In this study, we demonstrated that the enhancer of zeste homolog 2 (EZH2) and the histone methyltransferase of polycomb repressive complex 2 (PRC2) are involved in the migration, invasion, and EMT-like changes in TKS4-deficient cells (KO). EZH2 is responsible for the maintenance of the trimethylated lysine 27 on histone H3 (H3K27me3). Methods: We performed transcriptome sequencing, chromatin immunoprecipitation, protein and RNA quantitative studies, cell mobility, invasion, and proliferation studies combined with/without the EZH2 activity inhibitor 3-deazanoplanocine (DZNep). Results: We detected an elevation of global H3K27me3 levels in the TKS4 KO cells, which could be reduced with treatment with DZNep, an EZH2 inhibitor. Inhibition of EZH2 activity reversed the phenotypic effects of the knockout of TKS4, reducing the migration speed and wound healing capacity of the cells as well as decreasing the invasion capacity, while the decrease in cell proliferation became stronger. In addition, inhibition of EZH2 activity also reversed most epithelial and mesenchymal markers. We investigated the wider impact of TKS4 deletion on the gene expression profile of colorectal cancer cells using transcriptome sequencing of wild-type and TKS4 knockout cells, particularly before and after treatment with DZNep. Additionally, we observed changes in the expression of several protein-coding genes and long non-coding RNAs that showed a recovery in expression levels following EZH2 inhibition. Conclusions: Our results indicate that the removal of TKS4 causes a notable disruption in the gene expression pattern, leading to the disruption of several signal transduction pathways. Inhibiting the activity of EZH2 can restore most of these transcriptomics and phenotypic effects in colorectal carcinoma cells.},
	year = {2024},
	eissn = {2218-273X},
	orcid-numbers = {Jacksi, Mevan Fahmi Sami/0000-0003-4659-9015; Schad, Eva/0000-0002-3006-2910; Tantos, Agnes/0000-0003-1273-9841}
}

@article{MTMT:34755849,
	title = {Sleep and local field potential effect of the D2 receptor agonist bromocriptine during the estrus cycle and postpartum period in female rats},
	url = {https://m2.mtmt.hu/api/publication/34755849},
	author = {Tóth, Attila István and Keserű, Dóra and Pethő, Máté and Détári, László and Bencsik, Norbert and Dobolyi, Árpád and Hajnik, Tünde},
	doi = {10.1016/j.pbb.2024.173754},
	journal-iso = {PHARMACOL BIOCHEM BE},
	journal = {PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR},
	volume = {239},
	unique-id = {34755849},
	issn = {0091-3057},
	year = {2024},
	eissn = {1873-5177},
	orcid-numbers = {Tóth, Attila István/0000-0001-8607-8754; Détári, László/0000-0002-0630-8466; Bencsik, Norbert/0000-0001-9553-3851; Dobolyi, Árpád/0000-0003-0397-2991; Hajnik, Tünde/0000-0003-0684-8136}
}

@article{MTMT:34743931,
	title = {A neural network-based model framework for cell-fate decisions and development},
	url = {https://m2.mtmt.hu/api/publication/34743931},
	author = {Paczkó, Mátyás and Vörös, Dániel and Szabó, Péter and Jékely, Gáspár and Szathmáry, Eörs and Szilágyi, András},
	doi = {10.1038/s42003-024-05985-1},
	journal-iso = {COMMUN BIOL},
	journal = {COMMUNICATIONS BIOLOGY},
	volume = {7},
	unique-id = {34743931},
	abstract = {Gene regulatory networks (GRNs) fulfill the essential function of maintaining the stability of cellular differentiation states by sustaining lineage-specific gene expression, while driving the progression of development. However, accounting for the relative stability of intermediate differentiation stages and their divergent trajectories remains a major challenge for models of developmental biology. Here, we develop an empirical data-based associative GRN model (AGRN) in which regulatory networks store multilineage stage-specific gene expression profiles as associative memory patterns. These networks are capable of responding to multiple instructive signals and, depending on signal timing and identity, can dynamically drive the differentiation of multipotent cells toward different cell state attractors. The AGRN dynamics can thus generate diverse lineage-committed cell populations in a robust yet flexible manner, providing an attractor-based explanation for signal-driven cell fate decisions during differentiation and offering a readily generalizable modelling tool that can be applied to a wide variety of cell specification systems.},
	year = {2024},
	eissn = {2399-3642},
	orcid-numbers = {Paczkó, Mátyás/0000-0002-0162-7927; Vörös, Dániel/0000-0002-6543-3953; Jékely, Gáspár/0000-0001-8496-9836; Szathmáry, Eörs/0000-0001-5227-2997; Szilágyi, András/0000-0002-6894-4652}
}

@article{MTMT:34726766,
	title = {Association between mobile touchscreen devices (MTSDs) and the quality of parent-child interaction in preschoolers},
	url = {https://m2.mtmt.hu/api/publication/34726766},
	author = {Liszkai-Peres, Krisztina and Budai, Zsófia and Adrienn, Kocsis and Jurányi, Zsolt and Pogány, Ákos and Kampis, György and Miklósi, Ádám and Konok, Veronika},
	doi = {10.3389/frcha.2024.1330243},
	journal = {Frontiers in Child and Adolescent Psychiatry},
	volume = {3},
	unique-id = {34726766},
	year = {2024},
	eissn = {2813-4540},
	orcid-numbers = {Liszkai-Peres, Krisztina/0000-0001-9051-9591; Pogány, Ákos/0000-0001-9498-0158; Kampis, György/0000-0001-7373-9402; Miklósi, Ádám/0000-0003-4831-8985; Konok, Veronika/0000-0001-6660-3603}
}

@article{MTMT:34726473,
	title = {Neural evidence for referential understanding of object words in dogs},
	url = {https://m2.mtmt.hu/api/publication/34726473},
	author = {Boros, Marianna and Magyari, Lilla and Morvai, Boglárka and Raúl, Hernandez-Perez and Dror, Shany and Andics, Attila},
	doi = {10.1016/j.cub.2024.02.029},
	journal-iso = {CURR BIOL},
	journal = {CURRENT BIOLOGY},
	volume = {34},
	unique-id = {34726473},
	issn = {0960-9822},
	abstract = {Using words to refer to objects in the environment is a core feature of the human language faculty. Referential understanding assumes the formation of mental representations of these words1,2. Such understanding of object words has not yet been demonstrated as a general capacity in any non-human species,3 despite multiple behaviour-based case reports.4–10 In human event-related potential (ERP) studies, object word knowledge is typically tested using the semantic violation paradigm, where words are presented either with their referent (match) or another object (mismatch).11,12 Such mismatch elicits an N400 effect, a well-established neural correlate of semantic processing.12,13 Reports of preverbal infant N400 evoked by semantic violations14 asserts the use of this paradigm to probe mental representations of object words in nonverbal populations. Here, measuring dogs’ (Canis familiaris) ERPs to objects primed with matching or mismatching object words, we found a
		mismatch effect at a frontal electrode, with a latency (206-606 ms) comparable to the human N400. A greater difference for words that dogs knew better, according to owner reports, further supported a semantic interpretation of this effect. Semantic expectations emerged irrespective of vocabulary size, demonstrating the prevalence of referential understanding in dogs. These results provide the first neural evidence for object word knowledge in a non-human animal.},
	keywords = {N400; Comparative cognition; speech-processing; canine (dog)},
	year = {2024},
	eissn = {1879-0445},
	pages = {1750-1754},
	orcid-numbers = {Boros, Marianna/0000-0002-5811-1411; Morvai, Boglárka/0000-0001-6360-9284; Andics, Attila/0000-0002-5913-6100}
}