@article{MTMT:34720451,
	title = {A carvedilolterápia jelentősége a kardiovaszkuláris betegségek kezelésében},
	url = {https://m2.mtmt.hu/api/publication/34720451},
	author = {Ábrahám, György and Gajdán, Nikolett},
	journal-iso = {METABOLIZMUS},
	journal = {METABOLIZMUS},
	volume = {22},
	unique-id = {34720451},
	issn = {1589-7311},
	year = {2025},
	pages = {82-85},
	orcid-numbers = {Ábrahám, György/0000-0002-2272-2317}
}

@article{MTMT:34803172,
	title = {Left atrial strains in cardiac amyloidosis -does its subtype matter?},
	url = {https://m2.mtmt.hu/api/publication/34803172},
	author = {Nemes, Attila},
	doi = {10.1016/j.ijcard.2024.132078},
	journal-iso = {INT J CARDIOL},
	journal = {INTERNATIONAL JOURNAL OF CARDIOLOGY},
	unique-id = {34803172},
	issn = {0167-5273},
	year = {2024},
	eissn = {1874-1754},
	orcid-numbers = {Nemes, Attila/0000-0002-7570-6214}
}

@article{MTMT:34797929,
	title = {A pleiotropy scan to discover new susceptibility loci for pancreatic ductal adenocarcinoma},
	url = {https://m2.mtmt.hu/api/publication/34797929},
	author = {Giaccherini, M and Rende, M and Gentiluomo, M and Corradi, C and Archibugi, L and Ermini, S and Maiello, E and Morelli, L and van Eijck, C H J and Cavestro, G M and Schneider, M and Mickevicius, A and Adamonis, K and Basso, D and Hlavac, V and Gioffreda, D and Talar-Wojnarowska, R and Schöttker, B and Lovecek, M and Vanella, G and Gazouli, M and Uno, M and Malecka-Wojciesko, E and Vodicka, P and Goetz, M and Bijlsma, M F and Petrone, M C and Bazzocchi, F and Kiudelis, M and Szentesi, Andrea Ildikó and Carrara, S and Nappo, G and Brenner, H and Milanetto, A C and Soucek, P and Katzke, V and Peduzzi, G and Rizzato, C and Pasquali, C and Chen, X and Capurso, G and Hackert, T and Bueno-de-Mesquita, B and Uzunoglu, F G G and Hegyi, Péter and Greenhalf, W and Theodoropoulos, G E E and Sperti, C and Perri, F and Oliverius, M and Mambrini, A and Tavano, F and Farinella, R and Arcidiacono, P G and Lucchesi, M and Bunduc, Stefania and Kupcinskas, J and Di Franco, G and Stocker, S and Neoptolemos, J P and Bambi, F and Jamroziak, K and Testoni, S G G and Aoki, M N and Mohelnikova-Duchonova, B and Izbicki, J R and Pezzilli, R and Lawlor, R T and Kauffmann, E F and López de Maturana, E and Malats, N and Canzian, F and Campa, D},
	doi = {10.1093/mutage/geae012},
	journal-iso = {MUTAGENESIS},
	journal = {MUTAGENESIS},
	unique-id = {34797929},
	issn = {0267-8357},
	abstract = {Pleiotropic variants (i.e., genetic polymorphisms influencing more than one phenotype) are often associated with cancer risk. A scan of pleiotropic variants was successfully conducted ten years ago in relation to pancreatic ductal adenocarcinoma susceptibility. However, in the last decade, genetic association studies performed on several human traits have greatly increased the number of known pleiotropic variants. Based on the hypothesis that variants already associated with a least one trait have a higher probability of association with other traits, 61,052 variants reported to be associated by at least one genome wide association study (GWAS) with at least one human trait were tested in the present study consisting of two phases (discovery and validation), comprising a total of 16,055 pancreatic ductal adenocarcinoma (PDAC) cases and 212,149 controls. The meta-analysis of the two phases showed two loci (10q21.1-rs4948550 (P=6.52×10-5) and 7q36.3-rs288762 (P=3.03×10-5) potentially associated with PDAC risk. 10q21.1-rs4948550 shows a high degree of pleiotropy and it is also associated with colorectal cancer risk while 7q36.3-rs288762 is situated 28,558 base pairs upstream of the Sonic Hedgehog (SHH) gene, which is involved in the cell differentiation process and PDAC etiopathogenesis. In conclusion, none of the single nucleotide polymorphisms (SNPs) showed a formally statistically significant association after correction for multiple testing. However, given their pleiotropic nature and association with various human traits including colorectal cancer, the two SNPs showing the best associations with PDAC risk merit further investigation through fine mapping and ad hoc functional studies.},
	keywords = {single nucleotide polymorphism; genetic susceptibility; Pancreatic cancer; Pleiotropy},
	year = {2024},
	eissn = {1464-3804},
	orcid-numbers = {Szentesi, Andrea Ildikó/0000-0003-2097-6927; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:34796471,
	title = {Favipiravir does not improve viral clearance in mild to moderate COVID-19 – a systematic review and meta-analysis of randomized controlled trials},
	url = {https://m2.mtmt.hu/api/publication/34796471},
	author = {Bahar, Muhammad Akbar and Kusuma, Ikhwan Yuda and Visnyovszki, Ádám and Matuz, Mária and Benkő, Ria and Ferenci, Tamás and Szabó, Bálint Gergely and Hajdú, Edit and Pető, Zoltán and Csupor, Dezső},
	doi = {10.1016/j.heliyon.2024.e29808},
	journal-iso = {HELIYON},
	journal = {HELIYON},
	unique-id = {34796471},
	year = {2024},
	eissn = {2405-8440},
	orcid-numbers = {Matuz, Mária/0000-0002-7877-2399; Benkő, Ria/0000-0002-8009-8962; Csupor, Dezső/0000-0002-4088-3333}
}

@article{MTMT:34788779,
	title = {Are there Disease-Specific Functional Features of Cardiac Mechanics?},
	url = {https://m2.mtmt.hu/api/publication/34788779},
	author = {Nemes, Attila},
	doi = {10.31083/j.rcm2504137},
	journal-iso = {REV CARDIOVASC MED},
	journal = {REVIEWS IN CARDIOVASCULAR MEDICINE},
	volume = {25},
	unique-id = {34788779},
	issn = {1530-6550},
	year = {2024},
	eissn = {2153-8174},
	orcid-numbers = {Nemes, Attila/0000-0002-7570-6214}
}

@article{MTMT:34788761,
	title = {Diagnosis, Treatment and Long-Term Management of Vitamin B12 Deficiency in Adults: A Delphi Expert Consensus},
	url = {https://m2.mtmt.hu/api/publication/34788761},
	author = {Obeid, Rima and Andrès, Emmanuel and Češka, Richard and Hooshmand, Babak and Guéant-Rodriguez, Rosa-Maria and Prada, Gabriel Ioan and Sławek, Jarosław and Traykov, Latchezar and Ta Van, Binh and Várkonyi, Tamás and Reiners, Karlheinz},
	doi = {10.3390/jcm13082176},
	journal-iso = {J CLIN MED},
	journal = {JOURNAL OF CLINICAL MEDICINE},
	volume = {13},
	unique-id = {34788761},
	abstract = {Background/Objectives: Vitamin B12 deficiency can cause variable symptoms, which may be irreversible if not diagnosed and treated in a timely manner. We aimed to develop a widely accepted expert consensus to guide the practice of diagnosing and treating B12 deficiency. Methods: We conducted a scoping review of the literature published in PubMed since January 2003. Data were used to design a two-round Delphi survey to study the level of consensus among 42 experts. Results: The panelists agreed on the need for educational and organizational changes in the current medical practices for diagnosing and treating B12 deficiency. Recognition of clinical symptoms should receive the highest priority in establishing the diagnosis. There is agreement that the serum B12 concentration is useful as a screening marker and methylmalonic acid or homocysteine can support the diagnosis. Patient lifestyle, disease history, and medications can provide clues to the cause of B12 deficiency. Regardless of the cause of the deficiency, initial treatment with parenteral B12 was regarded as the first choice for patients with acute and severe manifestations of B12 deficiency. The use of high-dose oral B12 at different frequencies may be considered for long-term treatment. Prophylactic B12 supplementation should be considered for specific high-risk groups. Conclusions: There is a consensus that clinical symptoms need to receive more attention in establishing the diagnosis of B12 deficiency. B12 laboratory markers can support the diagnosis. The severity of clinical symptoms, the causes of B12 deficiency, and the treatment goals govern decisions regarding the route and dose of B12 therapy.},
	year = {2024},
	eissn = {2077-0383},
	orcid-numbers = {Obeid, Rima/0000-0002-0064-7029; Andrès, Emmanuel/0000-0002-7914-7616; Prada, Gabriel Ioan/0000-0002-4762-9581; Sławek, Jarosław/0000-0001-6816-0877; Várkonyi, Tamás/0000-0001-6833-3563; Reiners, Karlheinz/0000-0002-1093-1867}
}

@article{MTMT:34778284,
	title = {Autonomic function and specific right atrial functions - Is there a relationship? Correlations from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study},
	url = {https://m2.mtmt.hu/api/publication/34778284},
	author = {Nemes, Attila and Kormányos, Árpád and Orosz, Andrea and Ambrus, Nóra and Várkonyi, Tamás and Lengyel, Csaba Attila},
	doi = {10.1002/jcu.23672},
	journal-iso = {J CLIN ULTRASOUND},
	journal = {JOURNAL OF CLINICAL ULTRASOUND},
	unique-id = {34778284},
	issn = {0091-2751},
	abstract = {Similarly to the ventricles, the atria are under sympathetic/parasympathetic neural regulation. Accordingly, correlations were investigated between Ewing's standard cardiovascular reflex tests (SCRTs) and three-dimensional speckle-tracking echocardiography (3DSTE)-derived right atrial (RA) volumes and strains in healthy subjects.The study comprised 45 healthy adults, but 5 subjects were excluded due to inferior image quality for 3DSTE-derived RA assessments. The remaining 40 individuals being in sinus rhythm had a mean age of 35.1 ± 3.5 years (20 men). Two-dimensional, Doppler, 3DSTE and SCRTs were performed in all cases.RA maximum volume and total and passive RA stroke volumes correlated with the Valsalva ratio. Active RA stroke volume and emptying fraction showed correlations with 30/15 ratio. Peak global and mean segmental RA circumferential (CS) and longitudinal strains (LS) showed correlation with the Valsalva ratio. At atrial contraction, global RA-LS and mean segmental RA-CS showed correlations with the Valsalva ratio. Moreover, mean segmental RA-CS correlated with 30/15 ratio and mean segmental RA radial strain showed correlations with systolic blood pressure in response to standing. Autonomic neuropathy score correlated with peak global RA-LS.Autonomic function parameters have significant associations with specific RA functions in healthy adults, making the latter possible indicators of autonomic dysregulation.},
	keywords = {Echocardiography; Correlation; three-dimensional; Autonomic; Speckle-tracking; Right atrial},
	year = {2024},
	eissn = {1097-0096},
	orcid-numbers = {Nemes, Attila/0000-0002-7570-6214; Kormányos, Árpád/0000-0002-7052-2184; Várkonyi, Tamás/0000-0001-6833-3563; Lengyel, Csaba Attila/0000-0002-0434-0067}
}

@article{MTMT:34772955,
	title = {Endometrium development patterns and BMI groups among in vitro fertilization patients; prognostic aspects},
	url = {https://m2.mtmt.hu/api/publication/34772955},
	author = {Vedelek, Viktor and Petra, Bicskei and Mariann, Tábi and Biróné Lajkó, Noémi and Csaba, Ékes and Bereczki, Kristóf and Zsófia, Meixner-Csáti and Rita, Sinka and Vágvölgyi, Anna and Zádori, János},
	doi = {10.3389/fendo.2024.1379109},
	journal-iso = {FRONT ENDOCRINOL},
	journal = {FRONTIERS IN ENDOCRINOLOGY},
	volume = {15},
	unique-id = {34772955},
	issn = {1664-2392},
	year = {2024},
	eissn = {1664-2392},
	orcid-numbers = {Vágvölgyi, Anna/0000-0002-8810-700X}
}

@{MTMT:34768899,
	title = {The Relationship between Tricuspid Annular Longitudinal and Sphincter-Like Features of Its Function in Healthy Adults: Insights from the MAGYAR-Healthy Study},
	url = {https://m2.mtmt.hu/api/publication/34768899},
	author = {Nemes, Attila and Rácz, Gergely and Kormányos, Árpád and Ruzsa, Zoltán and Achim, Alexandru and Lengyel, Csaba Attila},
	booktitle = {Cardiovascular Diseases: From Basic Research to Clinical Application},
	unique-id = {34768899},
	year = {2024},
	pages = {155-164},
	orcid-numbers = {Nemes, Attila/0000-0002-7570-6214; Kormányos, Árpád/0000-0002-7052-2184; Ruzsa, Zoltán/0000-0002-2474-5723; Lengyel, Csaba Attila/0000-0002-0434-0067}
}

@article{MTMT:34760472,
	title = {Aromatase Inhibitors and Plasma Lipid Changes in Postmenopausal Women with Breast Cancer: A Systematic Review and Meta-Analysis},
	url = {https://m2.mtmt.hu/api/publication/34760472},
	author = {Bérczi, Bálint and Borbásné Farkas, Kornélia and Hegyi, Péter and Tóth, Barbara and Csupor, Dezső and Németh, Balázs and Lukács, Anita and Czumbel, László Márk and Kerémi, Beáta and Kiss, István and Szabó, Andrea and Varga, Gábor and Gerber, Gábor and Gyöngyi, Zoltán},
	doi = {10.3390/jcm13061818},
	journal-iso = {J CLIN MED},
	journal = {JOURNAL OF CLINICAL MEDICINE},
	volume = {13},
	unique-id = {34760472},
	abstract = {Background: Women are typically diagnosed with estrogen receptor-positive breast cancer around the postmenopausal period when declining estrogen levels initiate changes in lipid profiles. Aromatase inhibitors (AI) are used to prevent the progression of cancer; however, a further reduction in estrogen levels may have detrimental effects on lipid levels, which was our working hypothesis. Methods: Our meta-analysis was conducted on the lipid profiles of postmenopausal breast cancer patients at baseline and at different treatment time points. Results: We identified 15 studies, including 1708 patients. Studies using anastrozole (ANA), exemestane (EXE), letrozole (LET), and tamoxifen (TMX) were involved. Subgroup analyses revealed that 3- and 12-month administrations of LET and EXE lead to negative changes in lipid profiles that tend to alter the lipid profile undesirably, unlike ANA and TMX. Conclusions: Our results suggest that, despite statistically significant results, EXE and LET may not be sufficient to cause severe dyslipidemia in patients without cardiovascular comorbidities according to the AHA/ACC Guideline on the Management of Blood Cholesterol. However, the results may raise the question of monitoring the effects of AIs in patients, especially those with pre-existing cardiovascular risk factors such as dyslipidemia.},
	year = {2024},
	eissn = {2077-0383},
	orcid-numbers = {Borbásné Farkas, Kornélia/0000-0002-5349-6527; Hegyi, Péter/0000-0003-0399-7259; Tóth, Barbara/0000-0002-6086-8819; Csupor, Dezső/0000-0002-4088-3333; Németh, Balázs/0000-0002-4914-9872; Lukács, Anita/0000-0002-0746-8920; Czumbel, László Márk/0000-0002-5915-0383; Kerémi, Beáta/0000-0003-4000-9440; Szabó, Andrea/0000-0003-4949-9431; Varga, Gábor/0000-0002-5506-8198; Gerber, Gábor/0000-0003-0256-2608; Gyöngyi, Zoltán/0000-0001-9330-9119}
}