TY - JOUR AU - Ábrahám, György AU - Gajdán, Nikolett TI - A carvedilolterápia jelentősége a kardiovaszkuláris betegségek kezelésében JF - METABOLIZMUS J2 - METABOLIZMUS VL - 22 PY - 2025 IS - 2 SP - 82 EP - 85 PG - 4 SN - 1589-7311 UR - https://m2.mtmt.hu/api/publication/34720451 ID - 34720451 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Hegede, R AU - Pesei, Z AU - Berke, G AU - Németh, Balázs AU - Erőss, B AU - Farkas, G AU - Szentesi, A AU - Czakó, László AU - Sahin-Tóth, M AU - Hegyi, P AU - Hegyi, E TI - THE ROLE OF TRPV6 VARIANTS IN CHRONIC PANCREATITIS IN HUNGARY JF - CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE J2 - CENT EUR J GASTRO HEPATOL VL - 10 PY - 2024 IS - Suppl 1. SP - 96 EP - 96 PG - 1 SN - 2415-9107 UR - https://m2.mtmt.hu/api/publication/34853646 ID - 34853646 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Bokor, B AU - Hegyi, P AU - Németh, Balázs TI - GENOTÍPUS-FENOTÍPUS ÖSSZEFÜGGÉSEK VIZSGÁLATA ÖRÖKLETES HASNYÁLMIRIGY-GYULLADÁSBAN JF - CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE J2 - CENT EUR J GASTRO HEPATOL VL - 10 PY - 2024 IS - Suppl 1 SP - 79 EP - 79 PG - 1 SN - 2415-9107 UR - https://m2.mtmt.hu/api/publication/34853620 ID - 34853620 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Sandor, M AU - Demcsak, A AU - Németh, Balázs AU - Sahin-Toth, M TI - MISFOLDING TRYPSINOGEN MUTANT CAUSES CHRONIC PANCREATITIS IN A PRECLINCAL MOUSE MODEL JF - CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE J2 - CENT EUR J GASTRO HEPATOL VL - 10 PY - 2024 IS - Suppl 1 SP - 126 EP - 126 PG - 1 SN - 2415-9107 UR - https://m2.mtmt.hu/api/publication/34853561 ID - 34853561 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Stefanovics, Regina AU - Sándor, M AU - Sahin-Tóth, V AU - Németh, Balázs AU - Zhang, W AU - Abu-El-Haija, M AU - Sahin-Tóth, M TI - NOVEL CHYMOTRYPSIN C (CTRC) VARIANTS FROM REAL-LIFE GENETIC TESTING OF PEDIATRIC PANCREATITIS CASES JF - CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE J2 - CENT EUR J GASTRO HEPATOL VL - 10 PY - 2024 IS - Suppl 1 SP - 127 EP - 127 PG - 1 SN - 2415-9107 UR - https://m2.mtmt.hu/api/publication/34853537 ID - 34853537 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Stefanovics, Regina AU - Kun, Anasztázia Erzsébet AU - Vincze, Á AU - Izbéki, F AU - Erőss, B AU - Czakó, László AU - Hegyi, P AU - Szentesi, A AU - Hegyi, P AU - Németh, Balázs TI - INVESTIGATION OF THE GENETICLLY DETERMINED “O” BLOOD GROUP IN CHRONIC PANCREATITIS JF - CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE J2 - CENT EUR J GASTRO HEPATOL VL - 10 PY - 2024 IS - Suppl 1 SP - 127 EP - 128 PG - 2 SN - 2415-9107 UR - https://m2.mtmt.hu/api/publication/34853476 ID - 34853476 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Polanek, Evelin AU - Sisák, Anita AU - Molnár, Regina AU - Máté, Zsuzsanna AU - Horváth, Edina AU - Németh, Gábor AU - Orvos, Hajnalka AU - Paulik, Edit AU - Szabó, Andrea TI - A Study of Vitamin D Status and Its Influencing Factors among Pregnant Women in Szeged, Hungary: A Secondary Outcome of a Case–Control Study JF - NUTRIENTS J2 - NUTRIENTS VL - 16 PY - 2024 IS - 10 SP - 1431 SN - 2072-6643 DO - 10.3390/nu16101431 UR - https://m2.mtmt.hu/api/publication/34853055 ID - 34853055 AB - Adequate vitamin D (VD) intake during pregnancy is needed for fetal development and maternal health maintenance. However, while there is no doubt regarding its importance, there is not a unified recommendation regarding adequate intake. The main aim of our study was to measure the VD serum level of studied women, together with its potential influencing factors: demographic (i.e., age, level of education, relationship status and type of residence), conception and pregnancy related factors. Results are based on secondary data analyses of a retrospective case–control study of 100 preterm and 200 term pregnancies, where case and control groups were analyzed together. Data collection was based on a self-administered questionnaire, health documentation, and maternal serum VD laboratory tests. VD intake was evaluated by diet and dietary supplement consumption. According to our results, 68.1% of women took some kind of prenatal vitamin, and only 25.9% of them knew about its VD content. Only 12.1% of included women reached the optimal, 75 nmol/L serum VD level. Higher maternal serum levels were associated with early pregnancy care visits (p = 0.001), assisted reproductive therapy (p = 0.028) and advice from gynecologists (p = 0.049). A correlation was found between VD intake and serum levels (p < 0.001). Despite the compulsory pregnancy counselling in Hungary, health consciousness, VD intake and serum levels remain below the recommendations. The role of healthcare professionals is crucial during pregnancy regarding micronutrients intake and the appropriate supplementation dose. LA - English DB - MTMT ER - TY - JOUR AU - Fábián, Anna AU - Bor, Renáta AU - Vasas, Béla AU - Szűcs, Mónika AU - Tóth, Tibor AU - Bősze, Zsófia AU - Szántó, Kata Judit AU - Bacsur, Péter AU - Bálint, Anita AU - Farkas, Bernadett AU - Farkas, Klaudia AU - Milassin, Ágnes AU - Rutka, Mariann AU - Resál, Tamás AU - Molnár, Tamás AU - Szepes, Zoltán TI - Long-term outcomes after endoscopic removal of malignant colorectal polyps. Results from a 10-year cohort TS - Results from a 10-year cohort JF - WORLD JOURNAL OF GASTROINTESTINAL ENDOSCOPY J2 - WORLD J GASTROINTEST ENDOSC VL - 16 PY - 2024 IS - 4 SP - 193 EP - 205 PG - 13 SN - 1948-5190 DO - 10.4253/wjge.v16.i4.193 UR - https://m2.mtmt.hu/api/publication/34852892 ID - 34852892 AB - Choosing an optimal post-polypectomy management strategy of malignant colorectal polyps is challenging, and evidence regarding a surveillance-only strategy is limited.To evaluate long-term outcomes after endoscopic removal of malignant colorectal polyps.A single-center retrospective cohort study was conducted to evaluate outcomes after endoscopic removal of malignant colorectal polyps between 2010 and 2020. Residual disease rate and nodal metastases after secondary surgery and local and distant recurrence rate for those with at least 1 year of follow-up were investigated. Event rates for categorical variables and means for continuous variables with 95% confidence intervals were calculated, and Fisher's exact test and Mann-Whitney test were performed. Potential risk factors of adverse outcomes were determined with univariate and multivariate logistic regression models.In total, 135 lesions (mean size: 22.1 mm; location: 42% rectal) from 129 patients (mean age: 67.7 years; 56% male) were enrolled. The proportion of pedunculated and non-pedunculated lesions was similar, with en bloc resection in 82% and 47% of lesions, respectively. Tumor differentiation, distance from resection margins, depth of submucosal invasion, lymphovascular invasion, and budding were reported at 89.6%, 45.2%, 58.5%, 31.9%, and 25.2%, respectively. Residual tumor was found in 10 patients, and nodal metastasis was found in 4 of 41 patients who underwent secondary surgical resection. Univariate analysis identified piecemeal resection as a risk factor for residual malignancy (odds ratio: 1.74; P = 0.042). At least 1 year of follow-up was available for 117 lesions from 111 patients (mean follow-up period: 5.59 years). Overall, 54%, 30%, 30%, 11%, and 16% of patients presented at the 1-year, 3-year, 5-year, 7-year, and 9-10-year surveillance examinations. Adverse outcomes occurred in 9.0% (local recurrence and dissemination in 4 patients and 9 patients, respectively), with no difference between patients undergoing secondary surgery and surveillance only.Reporting of histological features and adherence to surveillance colonoscopy needs improvement. Long-term adverse outcome rates might be higher than previously reported, irrespective of whether secondary surgery was performed. LA - English DB - MTMT ER - TY - JOUR AU - Nemes, Attila AU - Kormányos, Árpád AU - Ambrus, Nóra AU - Lengyel, Csaba Attila TI - Global left ventricular strains and left atrial volumes are not associated in healthy adults – Detailed analysis from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study JF - IJC HEART & VASCULATURE J2 - IJC HEART VASCULATURE VL - 52 PY - 2024 PG - 7 SN - 2352-9067 DO - 10.1016/j.ijcha.2024.101411 UR - https://m2.mtmt.hu/api/publication/34852886 ID - 34852886 LA - English DB - MTMT ER - TY - JOUR AU - Jakab, Andrea Emese AU - Horváth, Edit AU - Molnár, Dorottya AU - Bukva, Mátyás AU - Bereczki, Csaba TI - Validation of the Meditech ABPM-06 24-hour blood pressure monitoring system in a pediatric population according to International Organization for Standardization Protocol 81060-2:2018 JF - BLOOD PRESSURE MONITORING J2 - BLOOD PRESS MONIT PY - 2024 SN - 1359-5237 DO - 10.1097/MBP.0000000000000701 UR - https://m2.mtmt.hu/api/publication/34851786 ID - 34851786 AB - Ambulatory blood pressure monitoring (ABPM) devices play a crucial role in diagnosing hypertension, not only in adults but also in pediatric patients. ABPM-06, the latest oscillometric device from Meditech Ltd. (Budapest, Hungary), is the focus of this study. The objective was to validate the ABPM-06 device using the International Organization for Standardization (ISO) 81060-2 : 2018 standard.A total of 86 healthy patients, consisting of 34 males and 52 females, aged between 3 and 17 years, were enrolled in this study. During the ambulatory phase, a total of 50 patients were enrolled, with 35 patients falling within the 3- to 12-year-old age range and 15 patients aged between 12 and 17 years. Additionally, for the dynamic test, 36 patients were selected, comprising of 10 individuals aged 3-12 years and 26 patients aged 12-17 years. These patients were recruited from the outpatient clinics of the Department of Pediatrics at Albert Szent-Györgyi University in Szeged, Hungary. The validation process involved utilizing the same-arm sequence protocol, both in resting positions and during stress testing.The ABPM-06 performed well in both clinical and ambulatory validations. In terms of validation criterion 1, the mean ± SD of the differences between the test device and reference blood pressure readings was -1.3 ± 3.5 mmHg for systolic and -0.1 ± 2.3 mmHg for diastolic, in children under the age of 12 years. For those over the age of 12 years, the mean ± SD of the differences was -2.8 ± 4.6 mmHg for systolic and -0.5 ± 2.7 mmHg for diastolic. Regarding the ambulatory validation, for children under 12 years old, the mean ± SD of the differences was -1.3 ± 3.5 mmHg for systolic and -0.1 ± 2.3 mmHg for diastolic. In the age group above 12 years, the mean ± SD of the differences was -2.8 ± 4.6 mmHg for systolic and -0.5 ± 2.7 mmHg for diastolic. Both tests successfully met the established criteria regarding the mean and SD values of the differences between the device readings and the observed SBP and DBP measurements.The ABPM-06 oscillometric device fully adheres to the ISO 81060-2 : 2018 standard requirements for ABPM determination in the pediatric population (ages 3-17 years). Consequently, this ABPM device proves to be suitable for effectively managing hypertension in children and adolescents. LA - English DB - MTMT ER -