@article{MTMT:34876112,
	title = {Egy ismeretlen betegség, a hisztaminintolerancia: okok, tünetek, kezelés},
	url = {https://m2.mtmt.hu/api/publication/34876112},
	author = {Kucsera, Eszter Márta and Csupor, Dezső},
	journal-iso = {GYÓGYSZERÉSZET},
	journal = {GYÓGYSZERÉSZET},
	volume = {68},
	unique-id = {34876112},
	issn = {0017-6036},
	year = {2024},
	pages = {246-253},
	orcid-numbers = {Csupor, Dezső/0000-0002-4088-3333}
}

@article{MTMT:34866802,
	title = {Fabrication of Ciprofloxacin-Loaded Sodium Alginate Nanobeads Coated with Thiol-Anchored Chitosan Using B-390 Encapsulator Following Optimization by DoE},
	url = {https://m2.mtmt.hu/api/publication/34866802},
	author = {Mukhtar, Mahwash and Pannonhalminé Csóka, Ildikó and Martinović, Josipa and Šelo, Gordana and Bucić-Kojić, Ana and Orosz, László and Paróczai, Dóra and Burián, Katalin and Ambrus, Rita},
	doi = {10.3390/pharmaceutics16060691},
	journal-iso = {PHARMACEUTICS},
	journal = {PHARMACEUTICS},
	volume = {16},
	unique-id = {34866802},
	issn = {1999-4923},
	abstract = {Most infectious diseases of the gastrointestinal tract can easily be treated by exploiting the already available antibiotics with the change in administration approach and delivery system. Ciprofloxacin (CIP) is used as a drug of choice for many bacterial infections; however, long-term therapy and off-site drug accumulation lead to an increased risk of tendinitis and peripheral neuropathy. To overcome this issue, nanotechnology is being exploited to encapsulate antibiotics within polymeric structures, which not only facilitates dose maintenance at the infection site but also limits off-site side effects. Here, sodium alginate (SA) and thiol-anchored chitosan (TC) were used to encapsulate CIP via a calcium chloride (CaCl2) cross-linker. For this purpose, the B-390 encapsulator was employed in the preparation of nanobeads using a simple technique. The hydrogel-like sample was then freeze-dried, using trehalose or mannitol as a lyoprotectant, to obtain a fine dry powder. Design of Experiment (DoE) was utilized to optimize the nanobead production, in which the influence of different independent variables was studied for their outcome on the polydispersity index (PDI), particle size, zeta potential, and percentage encapsulation efficiency (% EE). In vitro dissolution studies were performed in simulated saliva fluid, simulated gastric fluid, and simulated intestinal fluid. Antibacterial and anti-inflammatory studies were also performed along with cytotoxicity profiling. By and large, the study presented positive outcomes, proving the advantage of using nanotechnology in fabricating new delivery approaches using already available antibiotics.},
	year = {2024},
	eissn = {1999-4923},
	orcid-numbers = {Pannonhalminé Csóka, Ildikó/0000-0003-0807-2781; Šelo, Gordana/0000-0001-8383-6636; Bucić-Kojić, Ana/0000-0001-7283-5494; Burián, Katalin/0000-0003-1300-2374}
}

@{MTMT:34865772,
	title = {Insights into antibiotic utilisation. Pilot study from an emergency department},
	url = {https://m2.mtmt.hu/api/publication/34865772},
	author = {Papfalvi, Erika Piroska and Nacsa, Róbert and Matuz, Mária and Ruzsa, Roxána and Hambalek, Helga and Hajdú, Edit and Pető, Zoltán and Erdélyi, Péter and Soós, Gyöngyvér and Benkő, Ria},
	booktitle = {3rd Antimicrobial Resistance – Current State and Perspectives 2024},
	unique-id = {34865772},
	year = {2024},
	pages = {259-261},
	orcid-numbers = {Matuz, Mária/0000-0002-7877-2399; Benkő, Ria/0000-0002-8009-8962}
}

@{MTMT:34865735,
	title = {Different aspects of hungarian antibiotic use},
	url = {https://m2.mtmt.hu/api/publication/34865735},
	author = {Benkő, Ria and Papfalvi, Erika Piroska and Matuz, Mária},
	booktitle = {3rd Antimicrobial Resistance – Current State and Perspectives 2024},
	unique-id = {34865735},
	year = {2024},
	pages = {37-38},
	orcid-numbers = {Benkő, Ria/0000-0002-8009-8962; Matuz, Mária/0000-0002-7877-2399}
}

@CONFERENCE{MTMT:34855660,
	title = {Innovative dermal drug delivery formulation containing lidocaine compare with lidocaine ointment},
	url = {https://m2.mtmt.hu/api/publication/34855660},
	author = {Hasanpour, Feria and Berkó, Szilvia},
	booktitle = {VI. Symposium of Young Researchers on PharmaceuticalTechnology, Biotechnology and Regulatory Science},
	doi = {10.14232/syrptbrs.2024.46},
	unique-id = {34855660},
	year = {2024},
	pages = {46-46},
	orcid-numbers = {Berkó, Szilvia/0000-0002-3842-8876}
}

@article{MTMT:34854941,
	title = {Spray-Dried Chitosan Hydrogel Particles as a Potential Delivery System for Benzydamine Hydrochloride},
	url = {https://m2.mtmt.hu/api/publication/34854941},
	author = {Milenkova, Sofia and Ambrus, Rita and Mukhtar, Mahwash and Pilicheva, Bissera and Marudova, Maria},
	doi = {10.3390/gels10030189},
	journal-iso = {GELS-BASEL},
	journal = {GELS (BASEL)},
	volume = {10},
	unique-id = {34854941},
	abstract = {Chitosan, being a biocompatible and mucoadhesive polysaccharide, is one of the most preferred hydrogel-forming materials for drug delivery. The objectives of the present study are to obtain spray-dried microparticles based on low-molecular-weight chitosan and study their potential application as cargo systems for the orally active drug benzydamine hydrochloride. Three types of particles are obtained: raw chitosan particles (at three different concentrations), cross-linked with sodium tripolyphosphate (NaTPP) particles (at three different chitosan:NaTPP ratios), and particles coated with mannitol (at three different chitosan:mannitol ratios), all of them in the size range between 1 and 10 µm. Based on the loading efficiency and the yields of the formulated hydrogel particles, one model of each type is chosen for further investigation of the effect of the cross-linker or the excipient on the properties of the gel structures. The morphology of both empty and benzydamine hydrochloride-loaded chitosan particles was examined by scanning electron microscopy, and it was quite regular and spherical. Interactions and composition in the samples are investigated by Fourier-transformed infrared spectroscopy. The thermal stability and phase state of the drug and drug-containing polymer matrixes were tested by differential scanning calorimetry and X-ray powdered diffraction, revealing that the drug underwent a phase transition. A drug release kinetics study of the chosen gel-based structures in simulated saliva buffer (pH = 6.8) and mathematical modeling of the process were performed, indicating the Weibull model as the most appropriate one.},
	year = {2024},
	eissn = {2310-2861},
	pages = {189},
	orcid-numbers = {Milenkova, Sofia/0000-0001-8951-9332; Ambrus, Rita/0000-0001-5496-1710; Pilicheva, Bissera/0000-0002-5737-536X}
}

@article{MTMT:34854924,
	title = {Characterization of Grape Pomace Extract Microcapsules: The Influence of Carbohydrate Co-Coating on the Stabilization of Goat Whey Protein as a Primary Coating},
	url = {https://m2.mtmt.hu/api/publication/34854924},
	author = {Perković, Gabriela and Martinović, Josipa and Šelo, Gordana and Bucić-Kojić, Ana and Planinić, Mirela and Ambrus, Rita},
	doi = {10.3390/foods13091346},
	journal-iso = {FOODS},
	journal = {FOODS},
	volume = {13},
	unique-id = {34854924},
	issn = {2304-8158},
	abstract = {Both grape pomace and whey are waste products from the food industry that are rich in valuable ingredients. The utilization of these two by-products is becoming increasingly possible as consumer awareness of upcycling increases. The biological activities of grape pomace extract (GPE) are diverse and depend on its bioavailability, which is influenced by processes in the digestive system. In this work, goat whey protein (GW) was used as the primary coating to protect the phenolic compounds of GPE during the spray drying process. In addition, trehalose (T), sucrose (S), xylose (X), and maltodextrin (MD) were added to the goat whey proteins as co-coatings and protein stabilizers. All spray drying experiments resulted in microcapsules (MC) with a high encapsulation efficiency (77.6–95.5%) and yield (91.5–99.0%) and almost 100% recovery of phenolic compounds during the release test. For o-coumaric acid, the GW-coated microcapsules (MC) showed a bioavailability index of up to 731.23%. A semi-crystalline structure and hydrophilicity were characteristics of the MC coated with 10% T, S, X, or 5% MD. GW alone or in combination with T, S, MD, or X proved to be a promising carrier for polyphenols from grape pomace extract and ensured good bioavailability of these natural antioxidants.},
	year = {2024},
	eissn = {2304-8158},
	pages = {1346},
	orcid-numbers = {Šelo, Gordana/0000-0001-8383-6636; Bucić-Kojić, Ana/0000-0001-7283-5494; Planinić, Mirela/0000-0003-3752-5989; Ambrus, Rita/0000-0001-5496-1710}
}

@article{MTMT:34854390,
	title = {„Agyfényesítés” vagy evidenciák nélküli gyógyszerabúzus? A piracetám alkalmazása Magyarországon [„Cognitive Enhancement" or non-evidence-based nootropic abuse? – Use of Piracetam in Hungary]},
	url = {https://m2.mtmt.hu/api/publication/34854390},
	author = {Érszegi, András and Vámos, Máté and Viola, Réka and Csupor, Dezső and Vágvölgyi, Anna},
	doi = {10.26430/CHUNGARICA.2024.54.2.141},
	journal-iso = {CARDIOL HUNG},
	journal = {CARDIOLOGIA HUNGARICA},
	volume = {54},
	unique-id = {34854390},
	issn = {0133-5596},
	year = {2024},
	eissn = {1588-0230},
	pages = {141-149},
	orcid-numbers = {Csupor, Dezső/0000-0002-4088-3333; Vágvölgyi, Anna/0000-0002-8810-700X}
}

@article{MTMT:34849164,
	title = {Pharmacists combating antimicrobial resistance: A Delphi study on antibiotic dispensing},
	url = {https://m2.mtmt.hu/api/publication/34849164},
	author = {Lambert, Maarten and Wonink, Anneloes and Benkő, Ria and Plejdrup Hansen, Malene and van Dijk, Liset and Taxis, Katja},
	doi = {10.1016/j.sapharm.2024.04.006},
	journal-iso = {RES SOC ADMIN PHARM},
	journal = {RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY},
	unique-id = {34849164},
	issn = {1551-7411},
	abstract = {The daily work of community pharmacists includes dispensing antibiotics, but little is known about how this should be done to ensure quality use of antibiotics.To define specific tasks of the community pharmacist when dispensing antibiotics and to assess to what extent these tasks can be implemented in practice in Europe.A Delphi study with community pharmacist experts in the European Economic Area. Statements on potential tasks for pharmacists during the antibiotic dispensing process were based on a systematic literature review. Participants rated the statements for importance and feasibility of implementation in practice in 3 rounds on a scale from 1 to 9. Consensus of importance was defined as ≥ 80 % of experts rating a statement between 7 and 9. An online expert meeting was conducted between rounds 1 and 2. Scores for all statements were analysed descriptively.Overall, 38 experts from 21 countries participated in the study. Experts reached consensus on 108 statements within 5 themes: 1) collaboration with prescribers, 2) checking prescriptions and dispensing, 3) counselling, 4) education, and 5) pharmacy services. Potential tasks included advising and collaborating with prescribers, performing safety checks, and having access to specific prescription information. Additionally, pharmacists should counsel patients related to the dispensed antibiotic and on antimicrobial resistance and infectious diseases. With few exceptions, pharmacists should not dispense antibiotics without prescriptions or prescribe antibiotics. Consensus on feasibility of implementation was only reached for statements in the categories "counselling patients" and "education". Barriers to changing practice included structure of the healthcare system, resistance to change from prescribers or pharmacy staff, lack of time and finances, legal barriers, and patient expectations.Community pharmacists have an important role when dispensing antibiotics. This study provides important steps towards better community pharmacy antibiotic dispensing practices throughout the EEA.},
	keywords = {antibiotics; ANTIMICROBIAL RESISTANCE; Delphi study; Community pharmacy; European Economic area; Dispensing practice},
	year = {2024},
	eissn = {1934-8150},
	orcid-numbers = {Benkő, Ria/0000-0002-8009-8962}
}

@article{MTMT:34849152,
	title = {Magyar vonatkozások egy nemzetközi kórképben. A Journal of Sleep Research által 2023-ban kiadott, az insomnia kezelését célzó terápiás irányelv áttekintése},
	url = {https://m2.mtmt.hu/api/publication/34849152},
	author = {Pintér, Dávid and Balogh, Andrea and Benkő, Ria and Tóth, Erika Hajnalka},
	journal-iso = {GYÓGYSZERÉSZET},
	journal = {GYÓGYSZERÉSZET},
	volume = {68},
	unique-id = {34849152},
	issn = {0017-6036},
	year = {2024},
	pages = {188-197},
	orcid-numbers = {Benkő, Ria/0000-0002-8009-8962}
}