TY - JOUR AU - Csukly, Gábor AU - Orbán-Szigeti, Boglárka AU - Suri, Karolin Mária AU - Zsigmond, Réka Ildikó AU - Hermán, Levente AU - Simon, Viktória AU - Kabaji, Anita AU - Bata, Barnabás AU - Hársfalvi, Péter AU - Vass, Edit AU - Csibri, Éva AU - Farkas, Kinga AU - Réthelyi, János TI - Theta-burst rTMS in schizophrenia to ameliorate negative and cognitive symptoms: study protocol for a double-blind, sham-controlled, randomized clinical trial JF - TRIALS J2 - TRIALS VL - 25 PY - 2024 IS - 1 PG - 11 SN - 1745-6215 DO - 10.1186/s13063-024-08106-9 UR - https://m2.mtmt.hu/api/publication/34804337 ID - 34804337 N1 - Funding Agency and Grant Number: Nemzeti Kutatsi, Fejlesztsi s Innovacis Alap Funding text: Not applicable. LA - English DB - MTMT ER - TY - JOUR AU - Nagy, Boglárka AU - Kojouharova, Petia Steftcheva AU - Protzner, Andrea B. AU - Gaál, Zsófia Anna TI - Investigating the Effect of Contextual Cueing with Face Stimuli on Electrophysiological Measures in Younger and Older Adults JF - JOURNAL OF COGNITIVE NEUROSCIENCE J2 - J COGNITIVE NEUROSCI VL - 36 PY - 2024 IS - 5 SP - 776 EP - 799 PG - 24 SN - 0898-929X DO - 10.1162/jocn_a_02135 UR - https://m2.mtmt.hu/api/publication/34782072 ID - 34782072 N1 - Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural SciencesBudapest, Hungary Department of Cognitive Science, Faculty of Natural Sciences, Budapest University of Technology and EconomicsBudapest, Hungary Department of Psychology, University of Calgary, Calgary, AB, Canada Export Date: 26 April 2024 AB - Extracting repeated patterns from our surroundings plays a crucial role in contextualizing information, making predictions, and guiding our behavior implicitly. Previous research showed that contextual cueing enhances visual search performance in younger adults. In this study, we investigated whether contextual cueing could also improve older adults' performance and whether age-related differences in the neural processes underlying implicit contextual learning could be detected. Twenty-four younger and 25 older participants performed a visual search task with contextual cueing. Contextual information was generated using repeated face configurations alongside random new configurations. We measured RT difference between new and repeated configurations; ERPs to uncover the neural processes underlying contextual cueing for early (N2pc), intermediate (P3b), and late (r-LRP) processes; and multiscale entropy and spectral power density analyses to examine neural dynamics. Both younger and older adults showed similar contextual cueing benefits in their visual search efficiency at the behavioral level. In addition, they showed similar patterns regarding contextual information processing: Repeated face configurations evoked decreased finer timescale entropy (1–20 msec) and higher frequency band power (13–30 Hz) compared with new configurations. However, we detected age-related differences in ERPs: Younger, but not older adults, had larger N2pc and P3b components for repeated compared with new configurations. These results suggest that contextual cueing remains intact with aging. Although attention- and target-evaluation-related ERPs differed between the age groups, the neural dynamics of contextual learning were preserved with aging, as both age groups increasingly utilized more globally grouped representations for repeated face configurations during the learning process. LA - English DB - MTMT ER - TY - JOUR AU - Lontai, Livia AU - Elek, Lívia Priyanka AU - Balogh, Fruzsina AU - Angyal, Dorottya AU - Pajkossy, Péter AU - Gönczi, Lóránt AU - Lakatos, Péter László AU - Iliás, Ákos TI - Burden of Mental Health among Patients with Inflammatory Bowel Disease—A Cross-Sectional Study from a Tertiary IBD Center in Hungary JF - JOURNAL OF CLINICAL MEDICINE J2 - J CLIN MED VL - 13 PY - 2024 IS - 7 PG - 9 SN - 2077-0383 DO - 10.3390/jcm13072002 UR - https://m2.mtmt.hu/api/publication/34763005 ID - 34763005 N1 - Funding Agency and Grant Number: Semmelweis University, Department of Internal Medicine and Oncology Funding text: Publication of this paper was supported by the Semmelweis University, Department of Internal Medicine and Oncology. AB - Background: Inflammatory bowel diseases (IBDs) are chronic conditions that negatively affect the patient’s quality of life. With the spread of the biopsychosocial model, the role of mental health in the activity and course of inflammatory bowel disease is becoming more and more recognized. Our study aimed to assess the prevalence of anxiety and depression in IBD patients in our tertiary referral center and determine the predictive factors of these mental conditions. Methods: A total of 117 patients were included consecutively between 1 December 2021 and 28 February 2022. We used a questionnaire to gather demographic information, disease course, and IBD-specific symptoms. We assessed anxiety symptoms using the GAD-7 and depressive complaints using the PHQ-9 questionnaire. We evaluated disease activity using CDAI and pMayo scores. Results: Of the 117 patients (male/female: 63/54), 88 suffered from Crohn’s disease, and 29 were diagnosed with ulcerative colitis. Only 6 patients were taking medication for mood disorders, and 38 individuals sought mental support during their lifetime. A total of 15% of the population suffered from moderate–severe anxiety disorder, and 22% were affected by moderate–severe depression. The GAD-7 and PHQ9 values showed a significant correlation between the number of stools, bloody stools, abdominal pain, number of flare-ups, and CDAI scores. Conclusions: Our study confirmed that there is a high incidence of anxiety and depressive symptoms among IBD patients. Our results highlighted the symptoms that could be associated with mental disorders. It is important to assess the mental status of IBD patients to improve their quality of life. LA - English DB - MTMT ER - TY - JOUR AU - Csizmadia, Petra AU - Nagy, Boglárka AU - Kővári, Lili AU - Gaál, Zsófia Anna TI - Exploring the role of working memory gate opening process in creativity: An ERP study using the reference-back paradigm JF - BIOLOGICAL PSYCHOLOGY J2 - BIOL PSYCHOL VL - 187 PY - 2024 PG - 14 SN - 0301-0511 DO - 10.1016/j.biopsycho.2024.108765 UR - https://m2.mtmt.hu/api/publication/34718463 ID - 34718463 N1 - Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural Sciences, Magyar tudósok körútja 2, Budapest, H-1117, Hungary Department of Cognitive Science, Faculty of Natural Sciences, Budapest University of Technology and Economics, Műegyetem rkp. 3, Budapest, H-1111, Hungary Doctoral School of Psychology, Eötvös Loránd University, Kazinczy utca 23–27, Budapest, H-1075, Hungary Export Date: 18 March 2024 CODEN: BLPYA Correspondence Address: Csizmadia, P.; Institute of Cognitive Neuroscience and Psychology, Magyar tudósok körútja 2, Hungary; email: csizmadia.petra@ttk.hu Chemicals/CAS: dopamine, 51-61-6, 62-31-7 Funding details: Hungarian Scientific Research Fund, OTKA, K 132880 Funding details: Nemzeti Kutatási, Fejlesztési és Innovaciós Alap, NKFIA Funding text 1: The research was supported by the ÚNKP-22–3-II-BME-5 New National Excellence Program of the Ministry for Culture and Innovation from the source of the National Research, Development and Innovation Fund ; and by the Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund ( OTKA K 132880 ) LA - English DB - MTMT ER - TY - JOUR AU - Kéri, Szabolcs TI - Frontal asymmetry and physiological responses in religious and spiritual problems with and without conversion JF - RELIGION BRAIN AND BEHAVIOUR J2 - RELIGION BRAIN AND BEHAVIOUR PY - 2024 PG - 11 SN - 2153-599X DO - 10.1080/2153599X.2024.2307373 UR - https://m2.mtmt.hu/api/publication/34715227 ID - 34715227 N1 - Department of Cognitive Science, Budapest University of Technology and Economics, Budapest, Hungary Sztárai Institute, University of Tokaj, Sárospatak, Hungary Department of Physiology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Export Date: 4 March 2024 Correspondence Address: Kéri, S.; Department of Cognitive Science, Hungary; email: keri.szabolcs@ttk.bme.hu AB - Religious conversion is often associated with a negative emotional state accompanied by profound changes in sacred beliefs, values, attitudes, and practices. This negative emotional state is referred to as "Religious or Spiritual Problem" (RSP) in the revised 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR, 2022). The physiological and neuronal correlates of RSP and religious conversion are not known. Therefore, we measured lateralized frontal alpha-asymmetry, saliva cortisol levels, and heart rate in 24 individuals who experienced religious conversion with RSP, 23 individuals with RSP without religious conversion, and 20 problem-free controls with matched religiosity. In the baseline condition, participants read newspapers and listened to non-religious music; in the religious condition, they read Bible verses and listened to sacred music. Relative to the controls, both groups with RSP showed stress responses in the religious condition, including increased frontal alpha-asymmetry (left > right frontal activation), elevated saliva cortisol concentrations, and higher heart rate. Participants experiencing religious conversion displayed higher frontal alpha-asymmetry than those without conversion, but the cortisol levels and heart rate responses were similar in converters and non-converters. These results indicate that religious conversion with RSP demands a higher cognitive load than RSP alone. LA - English DB - MTMT ER - TY - JOUR AU - Boncz, Ádám AU - Szalárdy, Orsolya AU - Velősy, Péter Kristóf AU - Béres, Luca AU - Baumgartner, Robert AU - Winkler, István AU - Tóth, Brigitta TI - The effects of aging and hearing impairment on listening in noise JF - ISCIENCE J2 - ISCIENCE VL - 27 PY - 2024 IS - 4 PG - 15 SN - 2589-0042 DO - 10.1016/j.isci.2024.109295 UR - https://m2.mtmt.hu/api/publication/34630821 ID - 34630821 LA - English DB - MTMT ER - TY - JOUR AU - Zábó, Virág AU - Erát, Dávid AU - Gonda, Xénia AU - Harangozó, Judit AU - Iváncsics, Máté László AU - Vincze, Ágnes AU - Farkas, Judit AU - Balogh, Gábor AU - Oláh, Attila AU - Kéri, Szabolcs AU - Purebl, György AU - Vargha, András TI - Preliminary validation of the Mental Health Test in a psychiatric sample JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 14 PY - 2024 IS - 1 PG - 10 SN - 2045-2322 DO - 10.1038/s41598-024-54537-4 UR - https://m2.mtmt.hu/api/publication/34621193 ID - 34621193 N1 - Megosztott utolsó szerzőség AB - To assist psychiatrists and clinical psychologists to assess their patients’ psychological immune competence-based capacities and resources, depending on the mental health disorder diagnosis and the severity of the symptoms, the present study examined the psychometric properties of the Mental Health Test in a psychiatric sample. The research was carried out in four Hungarian healthcare facilities using a cross-sectional design. A total of 331 patients (140 male, 188 female, and 3 who preferred not to disclose their gender) completed the Mental Health Test, six well-being and mental health measures, and the Symptom Checklist-90. Psychiatrists and clinical psychologists reported the mental disorder status of each participant. Confirmatory factor analysis showed a good fit of the five-factor model to the data for the clinical version of the Mental Health Test (CFI = 0.972, RMSEA = 0.034). High internal consistency coefficients (α: 0.70–0.84; ω: 0.71–0.85) and excellent external and content validity were reported. The test is not sensitive to sociodemographic indicators but is sensitive to the correlates of well-being and to the symptoms of different types of mental disorders. Our preliminary findings suggest that the Mental Health Test is a suitable measure for assessing mental health capacities and resources in psychiatric samples. LA - English DB - MTMT ER - TY - JOUR AU - Csikós, Nóra AU - Petró, Béla AU - Kojouharova, Petia Steftcheva AU - Gaál, Zsófia Anna AU - Czigler, István TI - Automatic Change Detection in Interwoven Sequences: A Visual Mismatch Negativity Study JF - JOURNAL OF COGNITIVE NEUROSCIENCE J2 - J COGNITIVE NEUROSCI VL - 36 PY - 2024 IS - 3 SP - 534 EP - 550 PG - 17 SN - 0898-929X DO - 10.1162/jocn_a_02099 UR - https://m2.mtmt.hu/api/publication/34568378 ID - 34568378 N1 - Research Centre for Natural Sciences, HUN-REN, Budapest, Hungary Budapest University of Technology and Economics, Budapest, Hungary Pázmány Péter Catholic University, Budapest, Hungary Export Date: 23 February 2024 CODEN: JCONE Correspondence Address: Csikós, N.; Research Centre for Natural Sciences, Magyar tudósok körútja 2, Hungary; email: csikos.nora@ttk.hu Funding details: Hungarian Scientific Research Fund, OTKA Funding details: Nemzeti Kutatási, Fejlesztési és Innovaciós Alap, NKFIA Funding text 1: Project no. 143178 has been implemented with the support provided by the Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund, financed under the Hungarian Scientific Research Fund (OTKA) funding scheme. AB - In this study, we investigated whether the cognitive system, known to be able to register regular visual event sequences and the violation of these sequences automatically, had the capacity of processing two sequences simultaneously. To this end, we measured the visual mismatch negativity (vMMN) component of ERPs as interwoven event sequences simultaneously presented to the left and right side of the screen. One of the sequences consisted of geometric patterns (diamonds); the other, photographs of human faces. In successive cycles, parts of the stimuli vanished and then re-appeared (the OFF/ON method). The vanishing parts served as either standard (frequently vanishing parts) or infrequent (deviant) events, but these events were task-irrelevant. The 20 adult participants (age 21.40 ± 2.72 years) performed a visual tracking task, with the OFF/ON task being a passive oddball paradigm. According to the results, both OFF and ON events, and both diamond and face stimuli elicited the vMMN component, showing that the system underlying this activity is capable of processing two event sequences if the sequences consist of fairly different kind of objects as stimuli. The sLORETA analysis showed that the source of vMMN was more frequent contralaterally to the deviant event, and the sources comprised loci from ventral and dorsal structures, as well as some anterior loci. LA - English DB - MTMT ER - TY - JOUR AU - Bankó, Éva Mária AU - Weiss, Béla AU - Hevesi, István AU - Manga, Annamária Eszter AU - Vakli, Pál AU - Havadi-Nagy, Menta AU - Kelemen, Rebeka AU - Somogyi, Eszter AU - Homolya, István AU - Bihari, Adél AU - Simon, Ádám AU - Nárai, Ádám AU - Tóth, Krisztina AU - Báthori, Noémi AU - Tomacsek, Vivien AU - Horváth, András Attila AU - Kamondi, Anita AU - Racsmány, Mihály AU - Dénes, Ádám AU - Simor, Péter AU - Kovács, Tibor AU - Hermann, Petra AU - Vidnyánszky, Zoltán TI - Study protocol of the Hungarian Longitudinal Study of Healthy Brain Aging (HuBA). JF - IDEGGYOGYASZATI SZEMLE / CLINICAL NEUROSCIENCE J2 - IDEGGYOGY SZEMLE VL - 77 PY - 2024 IS - 1-2 SP - 51 EP - 59 PG - 9 SN - 0019-1442 DO - 10.18071/isz.77.0051 UR - https://m2.mtmt.hu/api/publication/34568140 ID - 34568140 N1 - Funding Agency and Grant Number: Hungarian National Research, Development and Innovation Office [2019-2.1.7-ERANET-2020-00008]; European Union [RRF-2.3.1-21-202200015]; HUN-REN [0708-21 515 AT]; Ministry of Culture and Innovation of Hungary from the National-Research, Development, and Innovation Fund Funding text: This research was supported by the Hungarian National Research, Development and Innovation Office (grant number 2019-2.1.7-ERANET-2020-00008) and Project no. RRF-2.3.1-21-202200015, which has been implemented with the support provided by the European Union. This work was also supported by a grant from HUN-REN (0708-21 515 AT) to MR and ZV. NB was supported by the Ministry of Culture and Innovation of Hungary from the National-Research, Development, and Innovation Fund, financed under the TKP2021EGA funding scheme. We thank Szandra Pancsusak and Emilia Nagy for managing patient logistics and are very grateful to all participants for their time and participation in this study. AB - Neuro­cog­nitive aging and the associated brain diseases impose a major social and economic burden. Therefore, substantial efforts have been put into revealing the lifestyle, the neurobiological and the genetic underpinnings of healthy neurocognitive aging. However, these studies take place almost exclusively in a limited number of highly-developed countries. Thus, it is an important open question to what extent their findings may generalize to neurocognitive aging in other, not yet investigated regions. The purpose of the Hungarian Longitudinal Study of Healthy Brain Aging (HuBA) is to collect multi-modal longitudinal data on healthy neurocognitive aging to address the data gap in this field in Central and Eastern Europe..We adapted the Australian Ima­ging, Biomarkers and Lifestyle (AIBL) study of aging study protocol to local circumstances and collected demographic, lifestyle, men­tal and physical health, medication and medical history related information as well as re­cor­ded a series of magnetic resonance imaging (MRI) data. In addition, participants were al­so offered to participate in the collection of blood samples to assess circulating in­flam­matory biomarkers as well as a sleep study aimed at evaluating the general sleep quality based on multi-day collection of subjective sleep questionnaires and whole-night elec­troencephalographic (EEG) data..Baseline data collection has al­ready been accomplished for more than a hundred participants and data collection in the se­condsession is on the way. The collected data might reveal specific local trends or could also indicate the generalizability of previous findings. Moreover, as the HuBA protocol al­so offers a sleep study designed for tho­rough characterization of participants’ sleep quality and related factors, our extended multi-modal dataset might provide a base for incorporating these measures into healthy and clinical aging research. .Besides its straightforward na­tional benefits in terms of health ex­pen­di­ture, we hope that this Hungarian initiative could provide results valid for the whole Cent­ral and Eastern European region and could also promote aging and Alzheimer’s disease research in these countries.. LA - English DB - MTMT ER - TY - CHAP AU - Felletár, Fanni AU - Yang, Zijian Győző AU - Babarczy, Anna ED - Berend, Gábor ED - Gosztolya, Gábor ED - Vincze, Veronika TI - Az egészség jele a szöveg EGÉSZsége? - Szövegkoherencia borderline személyiségzavarban T2 - XX. Magyar Számítógépes Nyelvészeti Konferencia PB - Szegedi Tudományegyetem CY - online kiadás SN - 9789633069738 PY - 2024 SP - 201 EP - 214 PG - 14 UR - https://m2.mtmt.hu/api/publication/34560795 ID - 34560795 LA - Hungarian DB - MTMT ER -