@article{MTMT:34854961,
	title = {Secondary use of health data in te EU: Exploring the legal challanges of the upcoming European Health Data Space Regulation in light of the findings of the TEHDAS project},
	url = {https://m2.mtmt.hu/api/publication/34854961},
	author = {Davidovics, Krisztina and Kovács, Réka and Gaál, Péter},
	doi = {10.53020/IME-2024-KSZ-101},
	journal-iso = {IME},
	journal = {IME},
	volume = {23},
	unique-id = {34854961},
	issn = {1588-6387},
	abstract = {Arguably, big data, data processing with advanced ICT solutions and data sharing were accelerated during the end of the 2010s, also fuelled by the COVID-19 pandemic. This latter can be reasonably considered a booster in health care for data-driven digital solutions and regulations, which led to issues concerning both primary and secondary use of digital (electronic) health data. There is an ongoing and comprehensive regulatory effort within the European Union to address the evoked challenges. Regarding the healthcare sector, the European Health Data Space Regulation can be considered a flagship legislation. The main ambition of the European Commission is, on the one hand, to create a common space where natural persons can easily control their electronic health data and, on the other hand, to make it possible for researchers, innovators and policymakers to use these health data sets for common societal purposes in a trusted and secure way based on a specific cross-border digital infrastructure. A European Union project, the Joint Action Towards the European Health Data Space (TEHDAS) has been initiated to support the establishment of the EHDS as regards the secondary use of data. Our analysis identified two important topics: legislative barriers to the secondary use of health data and challenges for citizens’ empowerment, including data altruism. The legal complexity of the ongoing strategic legislative initiatives within the EU poses several challenges for future application. Firstly, there can be a terminological issue based on the lack of a common definition of secondary use of data. Secondly, the regulation of the Member States adjusted to their national health and data utilisation systems can be diverse. Both of these may hinder the desired EU-level harmonisation regarding data-sharing. In this context, the division of regulatory competencies related to health care and the chosen legal basis can be decisive. Overall, the EHDS might be a regulation that can challenge the current legal paradigm of competence distribution among the EU and the Member States regarding digital transition, including data usage in health care. As for the citizens’ empowerment, the goal of an EU-wide ecosystem of health data utilisation requires individuals who are aware of the economic value of their health data and, via practising altruism, want to use these data also for the common good. Specific provisions of the EHDS, such as the right to data portability or the option for opt-out, are definitely for the empowerment of citizens. But, these can also reduce the potential health care-related benefits of data utilisation at both, individual and population level. Altogether, a concert of requirements should be fulfilled for meaningful citizens’ participation, engagement, and practice of data altruism, supported by the complex interplay of the relevant regulations.},
	year = {2024},
	eissn = {1789-9974},
	pages = {5-15},
	orcid-numbers = {Davidovics, Krisztina/0000-0001-6081-3028; Kovács, Réka/0000-0003-4138-527X; Gaál, Péter/0000-0002-6815-9021}
}

@article{MTMT:34854898,
	title = {„Egészségpart” mobil nyári szűrő- és egészség-edukációs programsorozat: a 2021–2023. évek között megvalósult programok értékelése},
	url = {https://m2.mtmt.hu/api/publication/34854898},
	author = {Pénzes, Melinda and Mikesy, Gergely and Kenesei-Kalló, Andrea Dóra and Jóni, András Dániel and Lengyel, Lívia and Bertókné Tamás, Renáta and Árváné Egri, Csilla and Gál, Veronika and Joó, Tamás},
	doi = {10.53020/IME-2024-106},
	journal-iso = {IME},
	journal = {IME},
	volume = {23},
	unique-id = {34854898},
	issn = {1588-6387},
	abstract = {Számos országban az ún. mobil egészségklinikák egyrészt az egészségműveltséget javító, figyelemfelhívó és egészségedukációs mozgó platformként működnek, másrészt a daganatok- és más nem fertőző betegségek szűrésében is közreműködnek. A 2021-ben indított „Egészségpart” programsorozatunk célja a Balatonnál nyaraló, elsősorban munkaképes korú, magyar felnőtt lakosság számára ingyenes szűrések, életmód-tanácsadás és egészség-edukáció biztosítása a betegségek korai felismerése és az egészségműveltség javítása érdekében.Tanulmányunk célja a 2021–2023. évek nyári hónapjaiban, Balaton-parti településeken megvalósult, „Helybe visszük a szűrővizsgálatokat” szűrőprogramhoz kapcsolódó „Egészségpart” programsorozat értékelése bemeneti- (partnerség, humánerőforrás), folyamat- (aktivitások – szűrés és egészség-edukáció) és kimeneti (résztvevők száma és szociodemográfiai jellemzői) indikátorok alapján, leíró statisztikai elemzéssel.A három év során 13 „Egészségpart” nap valósult meg, átlagosan napi 18–31 humánerőforrás jelenléte és bővülő szakmai partnerségek mellett. A programaktivitások közül nem mindegyik volt jelen mindhárom évben, de összességében a szűrő- és egészség-edukációs aktivitások száma évről évre bővült (maximum 15, illetve 8 aktivitás). A szociodemográfiai adatokkal regisztrált résztvevők száma n=727–906 között alakult, átlagéletkoruk kissé 50 év feletti, a nők részvételi aránya 60% körüli volt, legnagyobb arányban minden évben a 45–64 éves korcsoport vett részt. A kiindulási évhez képest jelentősen emelkedett a >65 évesek érdeklődése a program iránt. A Balaton-környéki lakosok részvételi aránya az első évhez képest (27%) jelentősen megemelkedett a harmadik évre (53%).Az „Egészségpart” program komplex értékelése elengedhetetlen annak érdekében, hogy a későbbiekben fejlesztendő területek a programtervezésben és -megvalósításban azonosíthatókká váljanak. A résztvevők esetenként változó összetételére és igényeire dinamikus reagálás szükséges, valamint elengedhetetlen a szakmai partnerségek akár évről-évre történő felülvizsgálata és humánerőforrás allokálásának átgondolása.},
	year = {2024},
	eissn = {1789-9974},
	pages = {39-48},
	orcid-numbers = {Pénzes, Melinda/0000-0001-7396-4028; Mikesy, Gergely/0009-0009-7077-4806; Kenesei-Kalló, Andrea Dóra/0009-0007-9229-1683; Jóni, András Dániel/0000-0002-9397-487X; Lengyel, Lívia/0000-0001-7464-1829; Joó, Tamás/0000-0002-3551-6125}
}

@article{MTMT:34854873,
	title = {Az újraélesztési lánc fejlesztésének lehetőségei - egy országos adatokra épülő kutatás tanulságai},
	url = {https://m2.mtmt.hu/api/publication/34854873},
	author = {Mikesy, Gergely and Belicza, Éva and Sinka Lászlóné Adamik, Erika},
	doi = {10.53020/IME-2024-104},
	journal-iso = {IME},
	journal = {IME},
	volume = {23},
	unique-id = {34854873},
	issn = {1588-6387},
	abstract = {Bevezetés: A kórházi körülmények között bekövetkező szívhalál alapvetően gyakori eseménynek minősül. Az okok feltérképezése segíthet a megelőzésben, mert bár vannak olyan kórképek, amelyek esetében a kórházi körülmények között fellépő hirtelen szívmegálláskor esetén tökéletesen végrehajtott reanimáció sem hozhat pozitív eredményt, törekedni kell arra, hogy az újraélesztési folyamat megfelelő módon történjen, ne függhessen annak szervezettségétől a beteg túlélési esélye.Célkitűzés: Célunk, hogy felhívjuk a figyelmet az egészségügyi intézményekben végzett újraélesztések eredményességének növelési lehetőségeire.Módszer: A témában készült kutatás, valamint az azóta a NEVES rendszerbe érkezett adatok feldolgozása alapján mutatunk be összefüggéseket, illetve szakirodalmi- és intézményi jógyakorlatok bemutatásán keresztül igyekszünk fejlesztési javaslatokat bemutatni.Eredmények: Felmérésünk szerint hazánkban a kórházi körülmények között bekövetkezett szívhalálok reanimációinak során jelentős intézményi, osztályos, és eszköz rendelkezésre állási különbségek fedezhetők fel. Érdemes minden intézménynek saját felmérést készíteni tehát, viszont az az adatokból, és a bevont szakértők véleménye alapján is látszik, hogy az oktatásban, és a kommunikációs fejlesztések terén is több hazai intézményben lehetne újításokat bevezetni.Megbeszélés: Az intézményi szintű eredményesség javulásának egyik fontos kritériuma az ellátási feltételek megfelelőségének biztosítása, ugyanakkor az eszközös, és humán erőforrás fejlesztések, az újraélesztés, valamint az újraélesztési lánc működésének oktatása, valamint az intézményi kommunikáció javítása is a kórházak eredményességét javíthatják. Következtetés: Az újraélesztési lánc intézményi működése egy nagyon komplex folyamat, ahol a jól működő gyakorlat nem mindig párosul a sikeres újraélesztésekkel. Jelen közlemény célja az, hogy bemutassa az újraélesztési lánc esetleges hibás működése mögött meghúzódó okokat, és ezekre adekvát megoldási javaslatokat, működő jógyakorlatokat mutasson meg.},
	year = {2024},
	eissn = {1789-9974},
	pages = {25-33},
	orcid-numbers = {Mikesy, Gergely/0009-0009-7077-4806; Belicza, Éva/0000-0002-2472-1318; Sinka Lászlóné Adamik, Erika/0000-0003-2235-0434}
}

@article{MTMT:34854861,
	title = {Az intézményválasztás döntési háttere és páciensmotivációja a magánfinanszírozású nagyízületi protetikai műtétek esetében},
	url = {https://m2.mtmt.hu/api/publication/34854861},
	author = {Lengyel, Lívia and Lám, Judit},
	doi = {10.53020/IME-2024-103},
	journal-iso = {IME},
	journal = {IME},
	volume = {23},
	unique-id = {34854861},
	issn = {1588-6387},
	abstract = {Bevezetés A térdprotézis-műtéti páciensek klinikai eredményekkel kapcsolatos elvárásait megismerendő, valamint egy e célra fejlesztett nemzetközi mérőeszköz hazai statisztikai validálása céljából indítottunk kutatást 2023-ban. A kutatás egy részében azt is vizsgáltuk, milyen tényezők játszanak szerepet a magánintézményt választó páciensek döntésében.Módszerek A kutatás nulladik fázisában a kérdőívet pilot tesztnek vettettük alá mind csípő-, mind térdprotézis-műtéti páciensek körében. A válaszadókat az online térben, közösségi médiában rekrutáltuk tematikus betegcsoportokban, 2023 júliusa és szeptembere között.Eredmények A minta nagysága 393 fő, melynek 23,15%-a választott a csípő- vagy térdprotézis-műtétre magánkórházat. Jelen tanulmányban ennek a 91, magánkórházat választó páciensnek a motivációját, intézményválasztásának hátterét mutatjuk be. A műtéti helyszín kiválasztásánál az ortopéd sebész személye a leginkább befolyásoló tényező, a magánkórházat választók 87%-a először az operatőrről dönt.Következtetések Az ortopéd orvos szerepe mellett nem elhanyagolható, milyen információhoz jut hozzá a beteg, legyen az akár állami -, akár magánműtét. A hiteles, a beteg egészségértéséhez illeszkedő széleskörű tájékoztatás mellett a megalapozott döntéshez szükség lenne transzparenciára, mindkét szektor minőségi indikátorainak bemutatására.},
	year = {2024},
	eissn = {1789-9974},
	pages = {18-24},
	orcid-numbers = {Lengyel, Lívia/0000-0001-7464-1829; Lám, Judit/0000-0001-9621-1563}
}

@article{MTMT:34847239,
	title = {Intra-community link formation and modularity in ultracold growing hyperbolic networks},
	url = {https://m2.mtmt.hu/api/publication/34847239},
	author = {Balogh, Gáspár Sámuel and Palla, Gergely},
	doi = {10.1016/j.physa.2024.129784},
	journal-iso = {PHYSICA A},
	journal = {PHYSICA A - STATISTICAL MECHANICS AND ITS APPLICATIONS},
	volume = {642},
	unique-id = {34847239},
	issn = {0378-4371},
	year = {2024},
	eissn = {1873-2119},
	orcid-numbers = {Balogh, Gáspár Sámuel/0000-0003-3417-2655; Palla, Gergely/0000-0002-3406-4200}
}

@inbook{MTMT:34836887,
	title = {A megújulás záloga},
	url = {https://m2.mtmt.hu/api/publication/34836887},
	author = {Nyitrai, Imre},
	booktitle = {Szociális törvény 30},
	unique-id = {34836887},
	year = {2024},
	pages = {65-75},
	orcid-numbers = {Nyitrai, Imre/0000-0002-3159-1611}
}

@article{MTMT:34833220,
	title = {Autopsy findings in cancer patients infected with SARS-CoV-2 show a milder presentation of COVID-19 compared to non-cancer patients.},
	url = {https://m2.mtmt.hu/api/publication/34833220},
	author = {Kocsmár, Éva and Kocsmár, Ildikó and Elamin, Flóra and Pápai, Laura and Jakab, Ákos and Várkonyi, Tibor and Glasz, Tibor and Rácz, Gergely and Pesti, Adrián István and Danics, Krisztina and Kiss, András and Röst, Gergely and Belicza, Éva and Schaff, Zsuzsa and Lotz, Gábor},
	doi = {10.1007/s11357-024-01163-7},
	journal-iso = {GEROSCIENCE},
	journal = {GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE)},
	unique-id = {34833220},
	issn = {2509-2715},
	abstract = {COVID-19, caused by SARS-CoV-2, manifests with differing severity across distinct patient subgroups, with outcomes influenced by underlying comorbidities such as cancer, which may cause functional and compositional alterations of the immune system during tumor progression. We aimed to investigate the association of SARS-CoV-2 infection and its complications with cancer in a large autopsy series and the role of COVID-19 in the fatal sequence leading to death. A total of 2641 adult autopsies were investigated, 539 of these were positive for SARS-CoV-2. Among the total number of patients analyzed, 829 had active cancer. Overall, the cohort included 100 patients who simultaneously had cancer and SARS-CoV-2 infection. The course of COVID-19 was less severe in cancer patients, including a significantly lower incidence of viral and bacterial pneumonia, occurring more frequently as a contributory disease or coexisting morbidity, or as SARS-CoV-2 positivity without viral disease. SARS-CoV-2 positivity was more frequent among non-metastatic than metastatic cancer cases, and in specific tumor types including hematologic malignancies. COVID-19 was more frequently found to be directly involved in the fatal sequence in patients undergoing active anticancer therapy, but less frequently in perioperative status, suggesting that the underlying malignancy and consequent surgery are more important factors leading to death perioperatively than viral disease. The course of COVID-19 in cancer patients was milder and balanced during the pandemic. This may be due to relative immunosuppressed status, and the fact that even early/mild viral infections can easily upset their condition, leading to death from their underlying cancer or its complications.},
	keywords = {CANCER; pathology; Autopsy; pneumonia; COVID-19; SARS-CoV-2},
	year = {2024},
	eissn = {2509-2723},
	orcid-numbers = {Várkonyi, Tibor/0000-0002-8126-3982; Glasz, Tibor/0000-0003-2947-2733; Pesti, Adrián István/0000-0001-6706-6221; Danics, Krisztina/0000-0002-3694-5706; Kiss, András/0000-0002-7453-3163; Röst, Gergely/0000-0001-9476-3284; Belicza, Éva/0000-0002-2472-1318; Schaff, Zsuzsa/0000-0002-6429-8059; Lotz, Gábor/0000-0002-6921-8978}
}

@article{MTMT:34826914,
	title = {Does sensation-seeking behavior influence the patterns of flavored e-cigarette use? A cross-sectional study among Indonesian adolescents and young adults},
	url = {https://m2.mtmt.hu/api/publication/34826914},
	author = {Bigwanto, Mouhamad and Pénzes, Melinda and Urbán, Róbert},
	doi = {10.1186/s12889-024-18626-3},
	journal-iso = {BMC PUBLIC HEALTH},
	journal = {BMC PUBLIC HEALTH},
	volume = {24},
	unique-id = {34826914},
	issn = {1471-2458},
	year = {2024},
	eissn = {1471-2458},
	orcid-numbers = {Bigwanto, Mouhamad/0000-0002-8436-5140; Pénzes, Melinda/0000-0001-7396-4028; Urbán, Róbert/0000-0002-2058-5937}
}

@article{MTMT:34820174,
	title = {National strategies for knowledge translation in health policy-making: A scoping review of grey literature},
	url = {https://m2.mtmt.hu/api/publication/34820174},
	author = {Babarczy, Balázs and Scarlett, Julia and Sharma, Tarang and Gaál, Péter and Szécsényi-Nagy, Balázs and Kuchenmüller, Tanja},
	doi = {10.1186/s12961-023-01089-0},
	journal-iso = {HEALTH RES POLICY SY},
	journal = {HEALTH RESEARCH POLICY AND SYSTEMS},
	volume = {22},
	unique-id = {34820174},
	issn = {1478-4505},
	year = {2024},
	eissn = {1478-4505},
	orcid-numbers = {Gaál, Péter/0000-0002-6815-9021; Szécsényi-Nagy, Balázs/0000-0001-8016-8679}
}

@article{MTMT:34803496,
	title = {Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021. a systematic analysis for the Global Burden of Disease Study 2021},
	url = {https://m2.mtmt.hu/api/publication/34803496},
	author = {Ferrari, Alize J and Santomauro, Damian Francesco and Aali, Amirali and Abate, Yohannes Habtegiorgis and Abbafati, Cristiana and Abbastabar, Hedayat and Abd ElHafeez, Samar and Abdelmasseh, Michael and Abd-Elsalam, Sherief and Abdollahi, Arash and Abdullahi, Auwal and Abegaz, Kedir Hussein and Abeldaño Zuñiga, Roberto Ariel and Aboagye, Richard Gyan and Abolhassani, Hassan and Abreu, Lucas Guimarães and Abualruz, Hasan and Abu-Gharbieh, Eman and Abu-Rmeileh, Niveen ME and Ackerman, Ilana N and Addo, Isaac Yeboah and Addolorato, Giovanni and Adebiyi, Akindele Olupelumi and Adepoju, Abiola Victor and Adewuyi, Habeeb Omoponle and Afyouni, Shadi and Afzal, Saira and Afzal, Sina and Agodi, Antonella and Ahmad, Aqeel and Ahmad, Danish and Ahmad, Firdos and Ahmad, Shahzaib and Ahmed, Ali and Ahmed, Luai A and Ahmed, Muktar Beshir and Ajami, Marjan and Akinosoglou, Karolina and Akkaif, Mohammed Ahmed and Al Hasan, Syed Mahfuz and Alalalmeh, Samer O and Al-Aly, Ziyad and Albashtawy, Mohammed and Aldridge, Robert W and Alemu, Meseret Desalegn and Alemu, Yihun Mulugeta and Alene, Kefyalew Addis and Al-Gheethi, Adel Ali Saeed and Alharrasi, Maryam and Alhassan, Robert Kaba and Ali, Mohammed Usman and Ali, Rafat and Ali, Syed Shujait Shujait and Alif, Sheikh Mohammad and Aljunid, Syed Mohamed and Al-Marwani, Sabah and Almazan, Joseph Uy and Alomari, Mahmoud A and Al-Omari, Basem and Altaany, Zaid and Alvis-Guzman, Nelson and Alvis-Zakzuk, Nelson J and Alwafi, Hassan and Al-Wardat, Mohammad Sami and Al-Worafi, Yaser Mohammed and Aly, Safwat and Alzoubi, Karem H and Amare, Azmeraw T and Amegbor, Prince M and Ameyaw, Edward Kwabena and Amin, Tarek Tawfik and Amindarolzarbi, Alireza and Amiri, Sohrab and Amugsi, Dickson A and Ancuceanu, Robert and Anderlini, Deanna and Anderson, David B and Andrade, Pedro Prata and Andrei, Catalina Liliana and Ansari, Hossein and Antony, Catherine M and Anwar, Saleha and Anwar, Sumadi Lukman and Anwer, Razique and Anyanwu, Philip Emeka and Arab, Juan Pablo and Arabloo, Jalal and Arafat, Mosab and Araki, Daniel T and Aravkin, Aleksandr Y and Arkew, Mesay and Armocida, Benedetta and Arndt, Michael Benjamin and Arooj, Mahwish and Artamonov, Anton A and Aruleba, Raphael Taiwo and Arumugam, Ashokan and Ashbaugh, Charlie and Ashemo, Mubarek Yesse and Ashraf, Muhammad and Asika, Marvellous O and Askari, Elaheh and Astell-Burt, Thomas and Athari, Seyyed Shamsadin and Atorkey, Prince and Atout, Maha Moh'd Wahbi and Atreya, Alok and Aujayeb, Avinash and Ausloos, Marcel and Avan, Abolfazl and Awotidebe, Adedapo Wasiu and Awuviry-Newton, Kofi and Ayala Quintanilla, Beatriz Paulina and Ayuso-Mateos, Jose L and Azadnajafabad, Sina and Azevedo, Rui M S and Babu, Abraham Samuel and Badar, Muhammad and Badiye, Ashish D and Baghdadi, Soroush and Bagheri, Nasser and Bah, Sulaiman and Bai, Ruhai and Baker, Jennifer L and Bakkannavar, Shankar M and Bako, Abdulaziz T and Balakrishnan, Senthilkumar and Bam, Kiran and Banik, Palash Chandra and Barchitta, Martina and Bardhan, Mainak and Bardideh, Erfan and Barker-Collo, Suzanne Lyn and Barqawi, Hiba Jawdat and Barrow, Amadou and Barteit, Sandra and Barua, Lingkan and Bashiri Aliabadi, Somaye and Basiru, Afisu and Basu, Sanjay and Basu, Saurav and Bathini, Prapthi Persis and Batra, Kavita and Baune, Bernhard T and Bayileyegn, Nebiyou Simegnew and Behnam, Babak and Behnoush, Amir Hossein and Beiranvand, Maryam and Bejarano Ramirez, Diana Fernanda and Bell, Michelle L and Bello, Olorunjuwon Omolaja and Beloukas, Apostolos and Bensenor, Isabela M and Berezvai, Zombor and Bernabe, Eduardo and Bernstein, Robert S and Bettencourt, Paulo J G and Bhagavathula, Akshaya Srikanth and Bhala, Neeraj and Bhandari, Dinesh and Bhargava, Ashish and Bhaskar, Sonu and Bhat, Vivek and Bhatti, Gurjit Kaur and Bhatti, Jasvinder Singh and Bhatti, Manpreet S and Bhatti, Rajbir and Bhutta, Zulfiqar A and Bikbov, Boris and Bishai, Jessica Devin and Bisignano, Catherine and Bitra, Veera R and Bjørge, Tone and Bodolica, Virginia and Bodunrin, Aadam Olalekan and Bogale, Eyob Ketema and Bonakdar Hashemi, Milad and Bonny, Aime and Bora Basara, Berrak and Borhany, Hamed and Boxe, Christopher and Brady, Oliver J and Bragazzi, Nicola Luigi and Braithwaite, Dejana and Brant, Luisa C and Brauer, Michael and Breitner, Susanne and Brenner, Hermann and Brown, Julie and Brugha, Traolach and Bulamu, Norma B and Buonsenso, Danilo and Burkart, Katrin and Burns, Richard A and Busse, Reinhard and Bustanji, Yasser and Butt, Zahid A and Byun, Justin and Caetano dos Santos, Florentino Luciano and Calina, Daniela and Cámera, Luis Alberto and Campos-Nonato, Ismael R and Cao, Chao and Capodici, Angelo and Carr, Sinclair and Carreras, Giulia and Carugno, Andrea and Carvalho, Márcia and Castaldelli-Maia, Joao Mauricio and Castañeda-Orjuela, Carlos A and Castelpietra, Giulio and Catapano, Alberico L and Cattaruzza, Maria Sofia and Caye, Arthur and Cegolon, Luca and Cembranel, Francieli and Cenderadewi, Muthia and Cerin, Ester and Chakraborty, Promit Ananyo and Chan, Jeffrey Shi Kai and Chan, Raymond N C and Chandika, Rama Mohan and Chandrasekar, Eeshwar K and Charalampous, Periklis and Chattu, Vijay Kumar and Chatzimavridou-Grigoriadou, Victoria and Chen, Angela W and Chen, An-Tian and Chen, Catherine S and Chen, Haowei and Chen, Nathalie M and Cheng, Esther T W and Chimed-Ochir, Odgerel and Chimoriya, Ritesh and Ching, Patrick R and Cho, William C S and Choi, Sungchul and Chong, Bryan and Chong, Yuen Yu and Choudhari, Sonali Gajanan and Chowdhury, Rajiv and Christensen, Steffan Wittrup McPhee and Chu, Dinh-Toi and Chukwu, Isaac Sunday and Chung, Eric and Chung, Eunice and Chutiyami, Muhammad and Claassens, Mareli M and Cogen, Rebecca M and Columbus, Alyssa and Conde, Joao and Cortesi, Paolo Angelo and Cousin, Ewerton and Criqui, Michael H and Cruz-Martins, Natália and Dadras, Omid and Dai, Siyu and Dai, Xiaochen and Dai, Zhaoli and Dalaba, Maxwell Ayindenaba and 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Ikramullah and Khan, Maseer and Khan, Moien AB and Khanmohammadi, Shaghayegh and Khatab, Khaled and Khatami, Fatemeh and Khatatbeh, Moawiah Mohammad and Khater, Amir M and Khayat Kashani, Hamid Reza and Khidri, Feriha Fatima and Khodadoust, Elaheh and Khormali, Moein and Khorrami, Zahra and Kifle, Zemene Demelash and Kim, Min Seo and Kimokoti, Ruth W and Kisa, Adnan and Kisa, Sezer and Knudsen, Ann Kristin Skrindo and Kocarnik, Jonathan M and Kochhar, Sonali and Koh, Hyun Yong and Kolahi, Ali-Asghar and Kompani, Farzad and Koren, Gerbrand and Korzh, Oleksii and Kosen, Soewarta and Koulmane Laxminarayana, Sindhura Lakshmi and Krishan, Kewal and Krishna, Varun and Krishnamoorthy, Vijay and Kuate Defo, Barthelemy and Kuddus, Md Abdul and Kuddus, Mohammed and Kuitunen, Ilari and Kulkarni, Vishnutheertha and Kumar, Manasi and Kumar, Nithin and Kumar, Rakesh and Kurmi, Om P and Kusuma, Dian and Kyu, Hmwe Hmwe and La Vecchia, Carlo and Lacey, Ben and Ladan, Muhammad Awwal and Laflamme, Lucie and Lafranconi, Alessandra and Lahariya, Chandrakant and Lai, Daphne Teck Ching and Lal, Dharmesh Kumar and Lalloo, Ratilal and Lallukka, Tea and Lan, Qing and Lan, Tuo and Landires, Iván and Lanfranchi, Francesco and Langguth, Berthold and Laplante-Lévesque, Ariane and Larijani, Bagher and Larsson, Anders O and Lasrado, Savita and Lauriola, Paolo and Le, Huu-Hoai and Le, Long Khanh Dao and Le, Nhi Huu Hanh and Le, Trang Diep Thanh and Leasher, Janet L and Ledda, Caterina and Lee, Munjae and Lee, Paul H and Lee, Sang-woong and Lee, Seung Won and Lee, Wei-Chen and Lee, Yo Han and LeGrand, Kate E and Lenzi, Jacopo and Leong, Elvynna and Leung, Janni and Li, Ming-Chieh and Li, Wei and Li, Xiaopan and Li, Yichong and Li, Yongze and Lim, Lee-Ling and Lim, Stephen S and Lindstrom, Megan and Linn, Shai and Liu, Gang and Liu, Runben and Liu, Shiwei and Liu, Wei and Liu, Xiaofeng and Liu, Xuefeng and Llanaj, Erand and Lo, Chun-Han and López-Bueno, Rubén and Loreche, Arianna Maever and 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Bogdan and Odetokun, Ismail A and O'Donnell, Martin James and Oguntade, Ayodipupo Sikiru and Oguta, James Odhiambo and Okati-Aliabad, Hassan and Okeke, Sylvester Reuben and Okekunle, Akinkunmi Paul and Okonji, Osaretin Christabel and Olagunju, Andrew T and Olasupo, Omotola O and Olatubi, Matthew Idowu and Oliveira, Gláucia Maria Moraes and Olufadewa, Isaac Iyinoluwa and Olusanya, Bolajoko Olubukunola and Olusanya, Jacob Olusegun and Omar, Hany A and Omer, Goran Latif and Omonisi, Abidemi E Emmanuel and Onie, Sandersan and Onwujekwe, Obinna E and Ordak, Michal and Orish, Verner N and Ortega-Altamirano, Doris V and Ortiz, Alberto and Ortiz-Brizuela, Edgar and Osman, Wael M S and Ostroff, Samuel M and Osuagwu, Uchechukwu Levi and Otoiu, Adrian and Otstavnov, Nikita and Otstavnov, Stanislav S and Ouyahia, Amel and Ouyang, Guoqing and Owolabi, Mayowa O and P A, Mahesh Padukudru and Padron-Monedero, Alicia and Padubidri, Jagadish Rao and Palladino, Claudia and Pan, Feng and Pandi-Perumal, Seithikurippu R and Pangaribuan, Helena Ullyartha and Panos, Georgios D and Panos, Leonidas D and Pantea Stoian, Anca Mihaela and Pardhan, Shahina and Parikh, Romil R and Pashaei, Ava and Pasovic, Maja and Passera, Roberto and Patel, Jay and Patel, Sangram Kishor and Patil, Shankargouda and Patoulias, Dimitrios and Patthipati, Venkata Suresh and Pawar, Shrikant and Pazoki Toroudi, Hamidreza and Pease, Spencer A and Peden, Amy E and Pedersini, Paolo and Peng, Minjin and Pensato, Umberto and Pepito, Veincent Christian Filipino and Peprah, Emmanuel K and Peprah, Prince and Perdigão, João and Pereira, Maria Odete and Perianayagam, Arokiasamy and Perico, Norberto and Pesudovs, Konrad and Petermann-Rocha, Fanny Emily and Petri, William A and Pham, Hoang Tran and Philip, Anil K and Phillips, Michael R and Pigeolet, Manon and Pigott, David M and Pillay, Julian David and Piracha, Zahra Zahid and Pirouzpanah, Saeed and Plass, Dietrich and Plotnikov, Evgenii and Poddighe, Dimitri and Polinder, Suzanne and Postma, Maarten J and Pourtaheri, Naeimeh and Prada, Sergio I and Pradhan, Pranil Man Singh and Prakash, V and Prasad, Manya and Prates, Elton Junio Sady and Priscilla, Tina and Pritchett, Natalie and Puri, Pooja and Puvvula, Jagadeesh and Qasim, Nameer Hashim and Qattea, Ibrahim and Qazi, Asma Saleem and Qian, Gangzhen and Rabiee Rad, Mehrdad and Radhakrishnan, Raghu Anekal and Radhakrishnan, Venkatraman and Raeisi Shahraki, Hadi and Rafferty, Quinn and Raggi, Alberto and Raghav, Pankaja Raghav and Rahim, Md Jillur and Rahman, Md Mosfequr and Rahman, Mohammad Hifz Ur and Rahman, Mosiur and Rahman, Muhammad Aziz and Rahmani, Shayan and Rahmanian, Mohammad and Rahmawaty, Setyaningrum and Rajaa, Sathish and Ramadan, Mahmoud Mohammed and Ramasamy, Shakthi Kumaran and Ramasubramani, Premkumar and Ramazanu, Sheena and Rana, Kritika and Ranabhat, Chhabi Lal and Rancic, Nemanja and Rane, Amey and Rao, Chythra R and Rao, Kumuda and Rao, Mithun and Rao, Sowmya J and Rashidi, 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Setoguchi, Soko and Seylani, Allen and Shadid, Jamileh and Shafie, Mahan and Shah, Humaira and Shah, Nilay S and Shah, Pritik A and Shahbandi, Ataollah and Shahid, Samiah and Shahid, Wajeehah and Shahwan, Moyad Jamal and Shaikh, Masood Ali and Shakeri, Alireza and Shalash, Ali S and Sham, Sunder and Shamim, Muhammad Aaqib and Shamshirgaran, Mohammad Ali and Shamsi, Mohammad Anas and Shanawaz, Mohd and Shankar, Abhishek and Shannawaz, Mohammed and Sharath, Medha and Sharifan, Amin and Sharifi-Rad, Javad and Sharma, Manoj and Sharma, Rajesh and Sharma, Saurab and Sharma, Ujjawal and Sharma, Vishal and Shastry, Rajesh P and Shavandi, Amin and Shayan, Amir Mehdi and Shayan, Maryam and Shehabeldine, Amr Mohamed Elsayed and Shetty, Pavanchand H and Shibuya, Kenji and Shifa, Jemal Ebrahim and Shiferaw, Desalegn and Shiferaw, Wondimeneh Shibabaw and Shigematsu, Mika and Shiri, Rahman and Shitaye, Nebiyu Aniley and Shittu, Aminu and Shivakumar, K M and Shivarov, Velizar and Shokati Eshkiki, Zahra and Shool, Sina and Shrestha, Sunil and Shuval, Kerem and Sibhat, Migbar Mekonnen and Siddig, Emmanuel Edwar and Sigfusdottir, Inga Dora and Silva, Diego Augusto Santos and Silva, João Pedro and Silva, Luís Manuel Lopes Rodrigues and Silva, Soraia and Simpson, Colin R and Singal, Anjali and Singh, Abhinav and Singh, Balbir Bagicha and Singh, Harmanjit and Singh, Jasvinder A and Singh, Mahendra and Singh, Paramdeep and Skou, Søren T and Sleet, David A and Slepak, Erica Leigh N and Solanki, Ranjan and Soliman, Sameh S M and Song, Suhang and Song, Yimeng and Sorensen, Reed J D and Soriano, Joan B and Soyiri, Ireneous N and Spartalis, Michael and Sreeramareddy, Chandrashekhar T and Stark, Benjamin A and Starodubova, Antonina V and Stein, Caroline and Stein, Dan J and Steiner, Caitlyn and Steiner, Timothy J and Steinmetz, Jaimie D and Steiropoulos, Paschalis and Stockfelt, Leo and Stokes, Mark A and Subedi, Narayan Subedi and Subramaniyan, Vetriselvan and Suemoto, Claudia Kimie and Suleman, Muhammad and Suliankatchi Abdulkader, Rizwan and Sultana, Abida and Sundström, Johan and Swain, Chandan Kumar and Szarpak, Lukasz and Tabaee Damavandi, Payam and Tabarés-Seisdedos, Rafael and Tabatabaei Malazy, Ozra and Tabatabaeizadeh, Seyed-Amir and Tabatabai, Shima and Tabche, Celine and Tabish, Mohammad and Tadakamadla, Santosh Kumar and Taheri Abkenar, Yasaman and Taheri Soodejani, Moslem and Taherkhani, Amir and Taiba, Jabeen and Talaat, Iman M and Talukder, Ashis and Tampa, Mircea and Tamuzi, Jacques Lukenze and Tan, Ker-Kan and Tandukar, Sarmila and Tang, Haosu and Tavakoli Oliaee, Razieh and Tavangar, Seyed Mohammad and Teimoori, Mojtaba and Temsah, Mohamad-Hani and Teramoto, Masayuki and Thangaraju, Pugazhenthan and Thankappan, Kavumpurathu Raman and Thapar, Rekha and Thayakaran, Rasiah and Thirunavukkarasu, Sathish and Thomas, Nihal and Thomas, Nikhil Kenny and Thum, Chern Choong Chern and Tichopad, Ales and Ticoalu, Jansje Henny Vera and Tillawi, Tala and Tiruye, Tenaw Yimer and Tobe-Gai, Ruoyan and Tonelli, Marcello and Topor-Madry, Roman and Torre, Anna E and Touvier, Mathilde and Tovani-Palone, Marcos Roberto and Tran, Jasmine T and Tran, Mai Thi Ngoc and Tran, Nghia Minh and Tran, Ngoc-Ha and Trico, Domenico and Tromans, Samuel Joseph and Truyen, Thien Tan Tri Tai and Tsatsakis, Aristidis and Tsegay, Guesh Mebrahtom and Tsermpini, Evangelia Eirini and Tumurkhuu, Munkhtuya and Tyrovolas, Stefanos and Udoh, Arit and Umair, Muhammad and Umakanthan, Srikanth and Umar, Tungki Pratama and Undurraga, Eduardo A and Unim, Brigid and Unnikrishnan, Bhaskaran and Unsworth, Carolyn Anne and Upadhyay, Era and Urso, Daniele and Usman, Jibrin Sammani and Vahabi, Seyed Mohammad and Vaithinathan, Asokan Govindaraj and Van den Eynde, Jef and Varga, Orsolya and Varma, Ravi Prasad and Vart, Priya and Vasankari, Tommi Juhani and Vasic, Milena and Vaziri, Siavash and Vellingiri, Balachandar and Venketasubramanian, Narayanaswamy and Veroux, Massimiliano and Verras, Georgios-Ioannis and Vervoort, Dominique and Villafañe, Jorge Hugo and Violante, Francesco S and Vlassov, Vasily and Vollset, Stein Emil and Volovat, Simona Ruxandra and Vongpradith, Avina and Waheed, Yasir and Wang, Cong and Wang, Fang and Wang, Ning and Wang, Shu and Wang, Yanzhong and Wang, Yuan-Pang and Ward, Paul and Wassie, Emebet Gashaw and Weaver, Marcia R and Weerakoon, Kosala Gayan and Weintraub, Robert G and Weiss, Daniel J and Weldemariam, Abrha Hailay and Wells, Katherine M and Wen, Yi Feng and Whisnant, Joanna L and Whiteford, Harvey A and Wiangkham, Taweewat and Wickramasinghe, Dakshitha Praneeth and Wickramasinghe, Nuwan Darshana and Wilandika, Angga and Wilkerson, Caroline and Willeit, Peter and Wimo, Anders and Woldegebreal, Demewoz H and Wolf, Axel Walter and Wong, Yen Jun and Woolf, Anthony D and Wu, Chenkai and Wu, Felicia and Wu, Xinsheng and Wu, Zenghong and Wulf Hanson, Sarah and Xia, Yanjie and Xiao, Hong and Xu, Xiaoyue and Xu, Yvonne Yiru and Yadav, Lalit and Yadollahpour, Ali and Yaghoubi, Sajad and Yamagishi, Kazumasa and Yang, Lin and Yano, Yuichiro and Yao, Yao and Yaribeygi, Habib and Yazdanpanah, Mohammad Hosein and Ye, Pengpeng and Yehualashet, Sisay Shewasinad and Yesuf, Subah Abderehim and Yezli, Saber and Yiğit, Arzu and Yiğit, Vahit and Yigzaw, Zeamanuel Anteneh and Yismaw, Yazachew and Yon, Dong Keon and Yonemoto, Naohiro and Younis, Mustafa Z and Yu, Chuanhua and Yu, Yong and Yusuf, Hadiza and Zahid, Mondal Hasan and Zakham, Fathiah and Zaki, Leila and Zaki, Nazar and Zaman, Burhan Abdullah and Zamora, Nelson and Zand, Ramin and Zandieh, Ghazal G Z and Zar, Heather J and Zarrintan, Armin and Zastrozhin, Mikhail Sergeevich and Zhang, Haijun and Zhang, Ning and Zhang, Yunquan and Zhao, Hanqing and Zhong, Chenwen and Zhong, Panliang and Zhou, Juexiao and Zhu, Zhaohua and Ziafati, Makan and Zielińska, Magdalena and Zimsen, Stephanie R M and Zoladl, Mohammad and Zumla, Alimuddin and Zyoud, Samer H and Vos, Theo and Murray, Christopher J L},
	doi = {10.1016/S0140-6736(24)00757-8},
	journal-iso = {LANCET},
	journal = {LANCET},
	unique-id = {34803496},
	issn = {0140-6736},
	abstract = {Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate more rigorous monitoring of progress towards national and international health targets, such as the Sustainable Development Goals. For three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has filled that need. A global network of collaborators contributed to the production of GBD 2021 by providing, reviewing, and analysing all available data. GBD estimates are updated routinely with additional data and refined analytical methods. GBD 2021 presents, for the first time, estimates of health loss due to the COVID-19 pandemic.The GBD 2021 disease and injury burden analysis estimated years lived with disability (YLDs), years of life lost (YLLs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries using 100 983 data sources. Data were extracted from vital registration systems, verbal autopsies, censuses, household surveys, disease-specific registries, health service contact data, and other sources. YLDs were calculated by multiplying cause-age-sex-location-year-specific prevalence of sequelae by their respective disability weights, for each disease and injury. YLLs were calculated by multiplying cause-age-sex-location-year-specific deaths by the standard life expectancy at the age that death occurred. DALYs were calculated by summing YLDs and YLLs. HALE estimates were produced using YLDs per capita and age-specific mortality rates by location, age, sex, year, and cause. 95% uncertainty intervals (UIs) were generated for all final estimates as the 2·5th and 97·5th percentiles values of 500 draws. Uncertainty was propagated at each step of the estimation process. Counts and age-standardised rates were calculated globally, for seven super-regions, 21 regions, 204 countries and territories (including 21 countries with subnational locations), and 811 subnational locations, from 1990 to 2021. Here we report data for 2010 to 2021 to highlight trends in disease burden over the past decade and through the first 2 years of the COVID-19 pandemic.Global DALYs increased from 2·63 billion (95% UI 2·44-2·85) in 2010 to 2·88 billion (2·64-3·15) in 2021 for all causes combined. Much of this increase in the number of DALYs was due to population growth and ageing, as indicated by a decrease in global age-standardised all-cause DALY rates of 14·2% (95% UI 10·7-17·3) between 2010 and 2019. Notably, however, this decrease in rates reversed during the first 2 years of the COVID-19 pandemic, with increases in global age-standardised all-cause DALY rates since 2019 of 4·1% (1·8-6·3) in 2020 and 7·2% (4·7-10·0) in 2021. In 2021, COVID-19 was the leading cause of DALYs globally (212·0 million [198·0-234·5] DALYs), followed by ischaemic heart disease (188·3 million [176·7-198·3]), neonatal disorders (186·3 million [162·3-214·9]), and stroke (160·4 million [148·0-171·7]). However, notable health gains were seen among other leading communicable, maternal, neonatal, and nutritional (CMNN) diseases. Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47·8% (43·3-51·7) and for diarrhoeal diseases decreased by 47·0% (39·9-52·9). Non-communicable diseases contributed 1·73 billion (95% UI 1·54-1·94) DALYs in 2021, with a decrease in age-standardised DALY rates since 2010 of 6·4% (95% UI 3·5-9·5). Between 2010 and 2021, among the 25 leading Level 3 causes, age-standardised DALY rates increased most substantially for anxiety disorders (16·7% [14·0-19·8]), depressive disorders (16·4% [11·9-21·3]), and diabetes (14·0% [10·0-17·4]). Age-standardised DALY rates due to injuries decreased globally by 24·0% (20·7-27·2) between 2010 and 2021, although improvements were not uniform across locations, ages, and sexes. Globally, HALE at birth improved slightly, from 61·3 years (58·6-63·6) in 2010 to 62·2 years (59·4-64·7) in 2021. However, despite this overall increase, HALE decreased by 2·2% (1·6-2·9) between 2019 and 2021.Putting the COVID-19 pandemic in the context of a mutually exclusive and collectively exhaustive list of causes of health loss is crucial to understanding its impact and ensuring that health funding and policy address needs at both local and global levels through cost-effective and evidence-based interventions. A global epidemiological transition remains underway. Our findings suggest that prioritising non-communicable disease prevention and treatment policies, as well as strengthening health systems, continues to be crucially important. The progress on reducing the burden of CMNN diseases must not stall; although global trends are improving, the burden of CMNN diseases remains unacceptably high. Evidence-based interventions will help save the lives of young children and mothers and improve the overall health and economic conditions of societies across the world. Governments and multilateral organisations should prioritise pandemic preparedness planning alongside efforts to reduce the burden of diseases and injuries that will strain resources in the coming decades.Bill & Melinda Gates Foundation.},
	year = {2024},
	eissn = {1474-547X},
	orcid-numbers = {Joó, Tamás/0000-0002-3551-6125; Lám, Judit/0000-0001-9621-1563; Palicz, Tamás Gyula/0000-0003-3676-2878}
}