TY - JOUR AU - Radványi, Lilla AU - Balázs, Viktória Lilla AU - Kocsis, Béla AU - Csikós, Eszter AU - Ángyán, Virág Diána AU - Szabó, Péter AU - Biró, Viktória AU - Kocsis, Marianna AU - Farkas, Ágnes TI - Antibacterial activity of Hungarian varietal honeys against respiratory pathogens as a function of storage time JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 14 PY - 2024 IS - 1 PG - 12 SN - 2045-2322 DO - 10.1038/s41598-024-60961-3 UR - https://m2.mtmt.hu/api/publication/34836449 ID - 34836449 N1 - Export Date: 15 May 2024 AB - Today, antibiotic therapies that previously worked well against certain bacteria due to their natural sensitivity, are becoming less effective. Honey has been proven to inhibit the biofilm formation of some respiratory bacteria, however few data are available on how the storage time affects the antibacterial effect. The activity of black locust, goldenrod, linden and sunflower honeys from three consecutive years (2020, 2021, 2022) was analyzed in 2022 against Gram-negative (Haemophilus influenzae, H. parainfluenzae, Pseudomonas aeruginosa) and Gram-positive (Streptococcus pneumoniae) bacteria using in vitro microbiological methods. After determining the physicochemical parameters of honey, broth microdilution was applied to determine the minimum inhibitory concentration of each honey type against each bacterium, and crystal violet assay was used to test their antibiofilm effect. The possible mechanism of action was explored with membrane degradation test, while structural changes were illustrated with scanning electron microscopy. Honeys stored for one or two years were darker than fresh honeys, while older honeys had significantly lower antibacterial activity. The most remarkable inhibitory effect was exerted by linden and sunflower honeys, and P. aeruginosa proved to be the most resistant bacterium. Based on our results, honey intended for medicinal purposes should be used as fresh as possible during a treatment. LA - English DB - MTMT ER - TY - CONF AU - Mérész, Balázs AU - Bosnyák, Inez AU - Molitor, Dorottya AU - Kocsis, Béla AU - Borbásné Farkas, Kornélia AU - Reglődi, Dóra AU - Atlasz, Tamás AU - Váczy, Alexandra ED - Kovács, Bettina ED - Glázer-Kniesz, Adrienn ED - Tislér, Ádám TI - Potential new treatment target in bacterial keratitis T2 - Absztraktkötet: XII. Interdiszciplináris Doktorandusz Konferencia = Book of Abstract: XII. Interdisciplinary Doctoral Conference PB - Pécsi Tudományegyetem Doktorandusz Önkormányzat C1 - Pécs SN - 9789636262457 PY - 2024 SP - 154 EP - 154 PG - 1 UR - https://m2.mtmt.hu/api/publication/34826025 ID - 34826025 LA - English DB - MTMT ER - TY - JOUR AU - Dang, Nga Phuong AU - Petrich, Chris AU - Pasztor, Dorina AU - Schneider, György AU - Calay, Rajnish Kaur TI - Shewanella baltica in a Microbial Fuel Cell for Sensing of Biological Oxygen Demand (BOD) of Wastewater JF - ANALYTICAL LETTERS J2 - ANAL LETT PY - 2024 PG - 13 SN - 0003-2719 DO - 10.1080/00032719.2024.2341087 UR - https://m2.mtmt.hu/api/publication/34824870 ID - 34824870 N1 - Department of Cold Climate Technology, SINTEF Narvik, Narvik, Norway Department of Medical Microbiology and Immunology, University of Pécs, Medical School, Pécs, Hungary UiT–The Arctic University of Norway, Tromso, Norway Export Date: 6 May 2024 CODEN: ANALB Correspondence Address: Dang, N.P.; Department of Cold Climate Technology, Norway; email: nga.dang@sintef.no AB - Geobacter and Shewanella are the most characterized electroactive bacteria genera. Unlike genus Geobacter that is strictly anaerobic, Shewanella can grow under both oxic and anoxic environments and is capable of metabolizing a wider substrate range. In the present study, the use of strain Shewanella baltica 20 in MFC-based biosensor for BOD monitoring is reported. The S. baltica strain 20 was isolated from river sediment in Hungary. The bacterium could form a biofilm, oxidized glucose, and transferred electrons to produce current when they were enriched on the anode in an air cathode microbial fuel cell (MFC). The tested MFC system demonstrated linearity in the current response to glucose from 50 to 300 mg/L. The electrical efficiency was determined from the polarization curve using the method of Varying Circuit Resistance (VCR) with an external load probed from 10 ohm to 220 k ohm. The maximum power production was 1.2 mW/m2 at an external load of 40 k ohm. Studying the effect of external resistors on the MFC performance showed that the MFC reached higher saturation for 500 mg/L of glucose at lower resistances of 100 and 470 ohm, in comparison to 300 mg/L at 1000 ohm. The results show that the response of the MFC can potentially be tuned by adjusting the external load. Our preliminary study suggests that Shewanella baltica strain 20 may be used for online monitoring of BOD (biological oxygen demand) in wastewater. LA - English DB - MTMT ER - TY - CHAP AU - Bátai, István AU - Kerényi, Mónika ED - Vámos, Zoltán TI - Antimikróbás kezelés T2 - Súlyos baleseti agysérültek ellátása PB - Medicina Könyvkiadó CY - Budapest SN - 9789632269177 PY - 2024 SP - 190 EP - 191 PG - 2 UR - https://m2.mtmt.hu/api/publication/34823736 ID - 34823736 LA - Hungarian DB - MTMT ER - TY - CONF AU - Koloh, Regina AU - Farkas, Ágnes AU - Balázs, Viktória Lilla AU - Kocsis, Béla ED - Kovács, Bettina ED - Glázer-Kniesz, Adrienn ED - Tislér, Ádám TI - A gesztenyeméz biofilm képződést gátló hatása T2 - Absztraktkötet: XII. Interdiszciplináris Doktorandusz Konferencia = Book of Abstract: XII. Interdisciplinary Doctoral Conference PB - Pécsi Tudományegyetem Doktorandusz Önkormányzat C1 - Pécs SN - 9789636262457 PY - 2024 SP - 87 EP - 87 PG - 1 UR - https://m2.mtmt.hu/api/publication/34814487 ID - 34814487 LA - Hungarian DB - MTMT ER - TY - CONF AU - Nagy, Anett AU - Ormai, Edit AU - Horváth, Györgyi AU - Kocsis, Béla AU - Balázs, Viktória Lilla ED - Kovács, Bettina ED - Glázer-Kniesz, Adrienn ED - Tislér, Ádám TI - Mi az evidenciaalapú megközelítés alapján megítélt összefüggés a Pseudomonas aeruginosa baktérium és a kakukkfű illóolaj között? T2 - Absztraktkötet: XII. Interdiszciplináris Doktorandusz Konferencia = Book of Abstract: XII. Interdisciplinary Doctoral Conference PB - Pécsi Tudományegyetem Doktorandusz Önkormányzat C1 - Pécs SN - 9789636262457 PY - 2024 SP - 86 EP - 86 PG - 1 UR - https://m2.mtmt.hu/api/publication/34814458 ID - 34814458 LA - Hungarian DB - MTMT ER - TY - CONF AU - Ángyán, Virág Diána AU - Farkas, Ágnes AU - Kocsis, Béla AU - Radványi, Lilla ED - Kovács, Bettina ED - Glázer-Kniesz, Adrienn ED - Tislér, Ádám TI - Hársméz, levendula illóolaj és kombinációjuk antibakteriális aktivitása T2 - Absztraktkötet: XII. Interdiszciplináris Doktorandusz Konferencia = Book of Abstract: XII. Interdisciplinary Doctoral Conference PB - Pécsi Tudományegyetem Doktorandusz Önkormányzat C1 - Pécs SN - 9789636262457 PY - 2024 SP - 85 EP - 85 PG - 1 UR - https://m2.mtmt.hu/api/publication/34814440 ID - 34814440 LA - Hungarian DB - MTMT ER - TY - CONF AU - Ormai, Edit AU - Kocsis, Béla AU - Böszörményi, Andrea AU - Horváth, Györgyi AU - Balázs, Viktória Lilla ED - Kovács, Bettina ED - Glázer-Kniesz, Adrienn ED - Tislér, Ádám TI - Nozokomiális patogének és a szegfűszeg illóolaj kapcsolatának bemutatása evidenciaalapú megközelítésben T2 - Absztraktkötet: XII. Interdiszciplináris Doktorandusz Konferencia = Book of Abstract: XII. Interdisciplinary Doctoral Conference PB - Pécsi Tudományegyetem Doktorandusz Önkormányzat C1 - Pécs SN - 9789636262457 PY - 2024 SP - 83 EP - 83 PG - 1 UR - https://m2.mtmt.hu/api/publication/34814410 ID - 34814410 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Nörenberg, Jasper Maximilian AU - Vida, P. AU - Bösmeier, I. AU - Forró, B. AU - Nörenberg, A. AU - Buda, Á. AU - Simon, Diána AU - Erdő-Bonyár, Szabina AU - Jáksó, Pál AU - Kovács, Kálmán András AU - Mikó, Éva AU - Berki, Tímea AU - Mezősi, Emese AU - Barakonyi, Alíz TI - Decidual γδT cells of early human pregnancy produce angiogenic and immunomodulatory proteins while also possessing cytotoxic potential JF - FRONTIERS IN IMMUNOLOGY J2 - FRONT IMMUNOL VL - 15 PY - 2024 PG - 12 SN - 1664-3224 DO - 10.3389/fimmu.2024.1382424 UR - https://m2.mtmt.hu/api/publication/34796888 ID - 34796888 N1 - Journal Article; Research Support, Non-U.S. Gov't LA - English DB - MTMT ER - TY - JOUR AU - Balázs, Benigna AU - Boros, Ákos AU - Pankovics, Péter AU - Nagy, Gábor AU - Szekeres, Sándor AU - Urbán, Péter AU - Reuter, Gábor TI - Detection and complete genome characterization of a genogroup X (GX) sapovirus (family Caliciviridae) from a golden jackal (Canis aureus) in Hungary JF - ARCHIVES OF VIROLOGY J2 - ARCH VIROL VL - 169 PY - 2024 IS - 5 PG - 8 SN - 0304-8608 DO - 10.1007/s00705-024-06034-2 UR - https://m2.mtmt.hu/api/publication/34796272 ID - 34796272 N1 - Funding Agency and Grant Number: National Research, Development and Innovation Office [NKFIH FK134311]; University of Pecs Funding text: Funding was provided by the National Research, Development and Innovation Office (NKFIH FK134311).Open access funding provided by University of Pecs. AB - In this study, a novel genotype of genogroup X (GX) sapovirus (family Caliciviridae ) was detected in the small intestinal contents of a golden jackal ( Canis aureus ) in Hungary and characterised by viral metagenomics and next-generation sequencing techniques. The complete genome of the detected strain, GX/Dömsöd/DOCA-11/2020/HUN (PP105600), is 7,128 nt in length. The ORF1- and ORF2-encoded viral proteins (NSP, VP1, and VP2) have 98%, 95%, and 88% amino acid sequence identity to the corresponding proteins of genogroup GX sapoviruses from domestic pigs, but the nucleic acid sequence identity values for their genes are significantly lower (83%, 77%, and 68%). During an RT-PCR-based epidemiological investigation of additional jackal and swine samples, no other GX strains were detected, but a GXI sapovirus strain, GXI/Tótfalu/WBTF-10/2012/HUN (PP105601), was identified in a faecal sample from a wild boar ( Sus scrofa ). We report the detection of members of two likely underdiagnosed groups of sapoviruses (GX and GXI) in a golden jackal and, serendipitously, in a wild boar in Europe. LA - English DB - MTMT ER -